Retinal axon response to ephrin-As shows a graded, concentration-dependent transition from growth promotion to inhibition

Neuron

Volumn 42, Issue 5, 2004, Pages 717-730

  Hansen, Michael J ^a   Dallal, Gerard E ^b   Flanagan, John G ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN A2; EPHRIN A5;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETINA NERVE CELL; SIGNAL TRANSDUCTION; TOPOGRAPHY;

ANIMALS; AXONS; BLOTTING, WESTERN; BODY PATTERNING; BRAIN MAPPING; CELL LINE; CHICK EMBRYO; DIAGNOSTIC IMAGING; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; EPHRIN-A2; EPHRIN-A5; EPHRINS; FIBROBLASTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH CONES; HUMANS; IN SITU HYBRIDIZATION; KIDNEY; NEURAL INHIBITION; NEURAL NETWORKS (COMPUTER); RATS; RETINA; SUPERIOR COLLICULUS; TIME FACTORS; TRANSFECTION; VISUAL PATHWAYS;

EID: 2942534978     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2004.05.009     Document Type: Article

References (40)

1. Baier H., Bonhoeffer F. Axon guidance by gradients of a target-derived component. Science. 255:1992;472-475
2. Braisted J.E., McLaughlin T., Wang H.U., Friedman G.C., Anderson D.J., O'Leary D.D. Graded and lamina-specific distributions of ligands of EphB receptor tyrosine kinases in the developing retinotectal system. Dev. Biol. 191:1997;14-28
3. Brown A., Yates P.A., Burrola P., Ortuno D., Vaidya A., Jessell T.M., Pfaff S.L., O'Leary D.D., Lemke G. Topographic mapping from the retina to the midbrain is controlled by relative but not absolute levels of EphA receptor signaling. Cell. 102:2000;77-88
4. Cheng H.J., Nakamoto M., Bergemann A.D., Flanagan J.G. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell. 82:1995;371-381
5. Cohen-Cory S., Fraser S.E. Effects of brain-derived neurotrophic factor on optic axon branching and remodeling in vivo. Nature. 378:1995;192-196
6. Drescher U., Kremoser C., Handwerker C., Loschinger J., Noda M., Bonhoeffer F. In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases. Cell. 82:1995;359-370
7. Feldheim D.A., Vanderhaeghen P., Hansen M.J., Frisén J., Lu Q., Barbacid M., Flanagan J.G. Topographic guidance labels in a sensory projection to the forebrain. Neuron. 21:1998;1303-1313
8. Feldheim D.A., Kim Y.I., Bergemann A.D., Frisén J., Barbacid M., Flanagan J.G. Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping. Neuron. 25:2000;563-574
9. Feldheim D.A., Nakamoto M., Osterfield M., Gale N.W., DeChiara T.M., Rohatgi R., Yancopoulos G.D., Flanagan J.G. Loss-of-function analysis of EphA receptors in retinotectal mapping. J. Neurosci. 24:2004;2542-2550
10. Flanagan J.G., Vanderhaeghen P. The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci. 21:1998;309-345
11. Frisén J., Yates P.A., McLaughlin T., Friedman G.C., O'Leary D.D.M., Barbacid M. Ephrin-A5 (AL-1/RAGS) is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system. Neuron. 20:1998;235-243
12. Gao P.P., Yue Y., Cerretti D.P., Dreyfus C., Zhou R. Ephrin-dependent growth and pruning of hippocampal axons. Proc. Natl. Acad. Sci. USA. 96:1999;4073-4077
13. Gierer A. Model for the retino-tectal projection. Proc. R. Soc. Lond. B Biol. Sci. 218:1983;77-93
14. Goodhill G.J., Richards L.J. Retinotectal maps. molecules, models and misplaced data Trends Neurosci. 22:1999;529-534
15. Hattori M., Osterfield M., Flanagan J.G. Regulated cleavage of a contact-mediated axon repellent. Science. 289:2000;1360-1365
16. Hindges R., McLaughlin T., Genoud N., Henkemeyer M., O'Leary D.D. EphB forward signaling controls directional branch extension and arborization required for dorsal-ventral retinotopic mapping. Neuron. 35:2002;475-487
17. Holmberg J., Frisén J. Ephrins are not only unattractive. Trends Neurosci. 25:2002;239-243
18. Holmberg J., Clarke D.L., Frisén J. Regulation of repulsion versus adhesion by different splice forms of an Eph receptor. Nature. 408:2000;203-206
19. Honda H. Topographic mapping in the retinotectal projection by means of complementary ligand and receptor gradients. a computer simulation study J. Theor. Biol. 192:1998;235-246
20. Klein R. Excitatory Eph receptors and adhesive ephrin ligands. Curr. Opin. Cell Biol. 13:2001;196-203
21. Mann F., Ray S., Harris W., Holt C. Topographic mapping in dorsoventral axis of the Xenopus retinotectal system depends on signaling through ephrin-B ligands. Neuron. 35:2002;461-473
22. Marston D.J., Dickinson S., Nobes C.D. Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion. Nat. Cell Biol. 5:2003;879-888
23. McLaughlin T., Hindges R., Yates P.A., O'Leary D.D. Bifunctional action of ephrin-B1 as a repellent and attractant to control bidirectional branch extension in dorsal-ventral retinotopic mapping. Development. 130:2003;2407-2418
24. Monnier P.P., Sierra A., Macchi P., Deitinghoff L., Andersen J.S., Mann M., Flad M., Hornberger M.R., Stahl B., Bonhoeffer F., Mueller B.K. RGM is a repulsive guidance molecule for retinal axons. Nature. 419:2002;392-395
25. Monschau B., Kremoser C., Ohta K., Tanaka H., Kaneko T., Yamada T., Handwerker C., Hornberger M.R., Loschinger J., Pasquale E.B., et al. Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons. EMBO J. 16:1997;1258-1267
26. Nakamoto M., Cheng H.J., Friedman G.C., McLaughlin T., Hansen M.J., Yoon C.H., O'Leary D.D., Flanagan J.G. Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo. Cell. 86:1996;755-766
27. Niederkofler V., Salie R., Sigrist M., Arber S. Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J. Neurosci. 24:2004;808-818
28. Osterfield M., Kirschner M.W., Flanagan J.G. Graded positional information. interpretation for both fate and guidance Cell. 113:2003;425-428
29. Prestige M.C., Willshaw D.J. On a role for competition in the formation of patterned neural connexions. Proc. R. Soc. Lond. B Biol. Sci. 190:1975;77-98
30. Rosentreter S.M., Davenport R.W., Loschinger J., Huf J., Jung J., Bonhoeffer F. Response of retinal ganglion cell axons to striped linear gradients of repellent guidance molecules. J. Neurobiol. 37:1998;541-562
31. Sperry R. Chemoaffinity in the orderly growth of nerve fiber patterns and connections. Proc. Natl. Acad. Sci. USA. 50:1963;703-710
32. Stein E., Lane A.A., Cerretti D.P., Schoecklmann H.O., Schroff A.D., Van Etten R.L., Daniel T.O. Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses. Genes Dev. 12:1998;667-678
33. Thanos S., Dutting D. Outgrowth and directional specificity of fibers from embryonic retinal transplants in the chick optic tectum. Brain Res. 429:1987;161-179
34. Walter J., Kern-Veits B., Huf J., Stolze B., Bonhoeffer F. Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro. Development. 101:1987;685-696
35. Weinl C., Drescher U., Lang S., Bonhoeffer F., Loschinger J. On the turning of Xenopus retinal axons induced by ephrin-A5. Development. 130:2003;1635-1643
36. Wilkinson D.G. Multiple roles of EPH receptors and ephrins in neural development. Nat. Rev. Neurosci. 2:2001;155-164
37. Winslow J.W., Moran P., Valverde J., Shih A., Yuan J.Q., Wong S.C., Tsai S.P., Goddard A., Henzel W.J., Hefti F., et al. Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation. Neuron. 14:1995;973-981
38. Yates P.A., Holub A.D., McLaughlin T., Sejnowski T.J., O'Leary D.D. Computational modeling of retinotopic map development to define contributions of EphA-ephrinA gradients, axon-axon interactions, and patterned activity. J. Neurobiol. 59:2004;95-113
39. Yu T.W., Bargmann C.I. Dynamic regulation of axon guidance. Nat. Neurosci. Suppl. 4:2001;1169-1176
40. Zhang J.H., Cerretti D.P., Yu T., Flanagan J.G., Zhou R. Detection of ligands in regions anatomically connected to neurons expressing the Eph receptor Bsk. potential roles in neuron-target interaction J. Neurosci. 16:1996;7182-7192