Positions under positive selection-key for selectivity and potency of scorpion α-toxins

Molecular Biology and Evolution

Volumn 27, Issue 5, 2010, Pages 1025-1034

  Weinberger, Hagar ^a   Moran, Yehu ^a   Gordon, Dalia ^a   Turkov, Michael ^a   Kahn, Roy ^a   Gurevitz, Michael ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Positive selection; Scorpion alpha toxins; Toxin selectivity

Indexed keywords

ALPHA TOXIN; COMPLEMENTARY DNA; POLYPEPTIDE; SCORPION VENOM; VOLTAGE GATED SODIUM CHANNEL;

AMINO ACID SUBSTITUTION; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC SELECTION; GENETIC VARIABILITY; MAXIMUM LIKELIHOOD METHOD; MOLECULAR CLONING; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENETIC TREE; PHYLOGENY; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SCORPION; SEQUENCE ANALYSIS; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; ANIMALS; BASE SEQUENCE; EVOLUTION, MOLECULAR; INSECTS; ION CHANNEL GATING; LIKELIHOOD FUNCTIONS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; PHYLOGENY; RATS; SCORPION VENOMS; SCORPIONS; SELECTION, GENETIC; SODIUM CHANNELS;

BUTHIDAE; HEXAPODA; LEIURUS QUINQUESTRIATUS; LEIURUS QUINQUESTRIATUS HEBRAEUS; MAMMALIA; SCORPIONES;

EID: 77951610835     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msp310     Document Type: Article

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