Molecular cloning and functional expression of the alpha-scorpion toxin BotIII: Pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels

Peptides

Volumn 25, Issue 2, 2004, Pages 151-161

  Benkhadir, Khadija ^a   Kharrat, Riadh ^a   Cestèle, Sandrine ^b   Mosbah, Amor ^b   Rochat, Hervé ^b   El Ayeb, Mohamed ^a   Karoui, Habib ^a  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b CNRS   (France)

Author keywords

BotIII; Natural BotIII neurotoxin from the scorpion Buthus occitanus tunetanus with a carboxyl amidated C terminal extremity; RBotIII OH

Indexed keywords

ALPHA TOXIN; PEPTIDE DERIVATIVE; SCORPION VENOM; VOLTAGE GATED SODIUM CHANNEL;

AMIDATION; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EXON; GENE MUTATION; GENE SEQUENCE; INTRON; MALE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR BINDING; SEQUENCE ANALYSIS; TOXICITY TESTING;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; ION CHANNEL GATING; MALE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RATS; RATS, WISTAR; SCORPION VENOMS; SCORPIONS; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM CHANNELS;

BUTHUS OCCITANUS; BUTHUS OCCITANUS TUNETANUS; MAMMALIA; SCORPIONES;

EID: 1942420685     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2004.01.009     Document Type: Article

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