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Volumn 239, Issue 5, 2010, Pages 1365-1377

Lipid transport and signaling in Caenorhabditis elegans

Author keywords

Caenorhabditis elegans; Cholesterol; Dafachronic acid; Dauer formation; Daumone; Defecation; Germline; LDL; Lipid; Lipid signaling; Lipoprotein; Polyunsaturated fatty acids; PUFA; Reverse cholesterol transport; Sperm motility; Vitellogenin

Indexed keywords

FATTY ACID DERIVATIVE; LINOLEIC ACID; LIPOPROTEIN; PHEROMONE; POLYUNSATURATED FATTY ACID; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UBIQUINONE;

EID: 77951593598     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22234     Document Type: Review
Times cited : (25)

References (100)
  • 1
    • 0035806626 scopus 로고    scopus 로고
    • Effect of statin therapy on C-reactive protein levels: The pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study
    • Albert MA, Danielson E, Rifai N, Ridker PM. 2001. Effect of statin therapy on Creactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study. JAMA 286:64-70. (Pubitemid 32606333)
    • (2001) Journal of the American Medical Association , vol.286 , Issue.1 , pp. 64-70
    • Albert, M.A.1    Danielson, E.2    Rifai, N.3    Ridker, P.M.4
  • 2
    • 0034659485 scopus 로고    scopus 로고
    • Daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans
    • Antebi A, Yeh WH, Tait D, Hedgecock EM, Riddle DL. 2000. daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans. Genes Dev 14:1512-1527. (Pubitemid 30421843)
    • (2000) Genes and Development , vol.14 , Issue.12 , pp. 1512-1527
    • Antebi, A.1    Yeh, W.-H.2    Tait, D.3    Hedgecock, E.M.4    Riddle, D.L.5
  • 3
    • 38449083079 scopus 로고    scopus 로고
    • Obesity and the regulation of fat metabolism
    • Ashrafi K. 2007. Obesity and the regulation of fat metabolism. WormBook:1-20.
    • (2007) WormBook , pp. 1-20
    • Ashrafi, K.1
  • 4
    • 64249129511 scopus 로고    scopus 로고
    • Nuclear hormone receptor regulation of micro-RNAs controls developmental progression
    • Bethke A, Fielenbach N, Wang Z, Mangelsdorf DJ, Antebi A. 2009. Nuclear hormone receptor regulation of micro-RNAs controls developmental progression. Science 324:95-98.
    • (2009) Science , vol.324 , pp. 95-98
    • Bethke, A.1    Fielenbach, N.2    Wang, Z.3    Mangelsdorf, D.J.4    Antebi, A.5
  • 5
    • 34547876124 scopus 로고    scopus 로고
    • The physiological and molecular regulation of lipoprotein assembly and secretion
    • DOI 10.1039/b700706j
    • Blasiole DA, Davis RA, Attie AD. 2007. The physiological and molecular regulation of lipoprotein assembly and secretion. Mol Biosyst 3:608-619. (Pubitemid 47258227)
    • (2007) Molecular BioSystems , vol.3 , Issue.9 , pp. 608-619
    • Blasiole, D.A.1    Davis, R.A.2    Attie, A.D.3
  • 7
    • 33748523825 scopus 로고    scopus 로고
    • What keeps C. elegans regular: The genetics of defecation
    • DOI 10.1016/j.tig.2006.08.006, PII S0168952506002642
    • Branicky R, Hekimi S. 2006. What keeps C. elegans regular: the genetics of defecation. Trends Genet 22:571-579. (Pubitemid 44374130)
    • (2006) Trends in Genetics , vol.22 , Issue.10 , pp. 571-579
    • Branicky, R.1    Hekimi, S.2
  • 8
    • 0035675987 scopus 로고    scopus 로고
    • Phenotypic and suppressor analysis of defecation in clk-1 mutants reveals that reaction to changes in temperature is an active process in Caenorhabditis elegans
    • Branicky R, Shibata Y, Feng J, Hekimi S. 2001. Phenotypic and suppressor analysis of defecation in clk-1 mutants reveals that reaction to changes in temperature is an active process in Caenorhabditis elegans. Genetics 159:997-1006. (Pubitemid 34033446)
    • (2001) Genetics , vol.159 , Issue.3 , pp. 997-1006
    • Branicky, R.1    Shibata, Y.2    Feng, J.3    Hekimi, S.4
  • 9
    • 49649122219 scopus 로고    scopus 로고
    • The many intersecting pathways underlying apolipoprotein B secretion and degradation
    • Brodsky JL, Fisher EA. 2008. The many intersecting pathways underlying apolipoprotein B secretion and degradation. Trends Endocrinol Metab 19:254-259.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 254-259
    • Brodsky, J.L.1    Fisher, E.A.2
  • 10
    • 44349147323 scopus 로고    scopus 로고
    • MEC-2 and MEC-6 in the Caenorhabditis elegans sensory mechanotransduction complex: Auxiliary subunits that enable channel activity
    • DOI 10.1085/jgp.200709910
    • Brown AL, Liao Z, Goodman MB. 2008. MEC-2 and MEC-6 in the Caenorhabditis elegans sensory mechanotransduction complex: auxiliary subunits that enable channel activity. J Gen Physiol 131:605-616. (Pubitemid 351749200)
    • (2008) Journal of General Physiology , vol.131 , Issue.6 , pp. 605-616
    • Brown, A.L.1    Liao, Z.2    Goodman, M.B.3
  • 11
    • 33846671059 scopus 로고    scopus 로고
    • MTP inhibition as a treatment for dyslipidaemias: Time to deliver or empty promises?
    • Burnett JR, Watts GF. 2007. MTP inhibition as a treatment for dyslipidaemias: time to deliver or empty promises? Expert Opin Ther Targets 11:181-189.
    • (2007) Expert Opin Ther Targets , vol.11 , pp. 181-189
    • Burnett, J.R.1    Watts, G.F.2
  • 12
    • 34250760886 scopus 로고    scopus 로고
    • Small-molecule pheromones that control dauer development in Caenorhabditis elegans
    • DOI 10.1038/nchembio.2007.3, PII NCHEMBIO20073
    • Butcher RA, FujitaM, Schroeder FC, Clardy J. 2007. Small-molecule pheromones that control dauer development in Caenorhabditis elegans. Nat ChemBiol 3:420-422. (Pubitemid 46956322)
    • (2007) Nature Chemical Biology , vol.3 , Issue.7 , pp. 420-422
    • Butcher, R.A.1    Fujita, M.2    Schroeder, F.C.3    Clardy, J.4
  • 16
    • 0033180210 scopus 로고    scopus 로고
    • Fluoxetine-resistant mutants in C. elegans define a novel family of transmembrane proteins
    • DOI 10.1016/S1097-2765(00)80362-7
    • Choy RK, Thomas JH. 1999. Fluoxetine-resistant mutants in C. elegans define a novel family of transmembrane proteins. Mol Cell 4:143-152. (Pubitemid 29456883)
    • (1999) Molecular Cell , vol.4 , Issue.2 , pp. 143-152
    • Choy, R.K.M.1    Thomas, J.H.2
  • 17
    • 33644787031 scopus 로고    scopus 로고
    • Fluoxetine-resistance genes in Caenorhabditis elegans function in the intestine and may act in drug transport
    • Choy RK, Kemner JM, Thomas JH. 2006. Fluoxetine-resistance genes in Caenorhabditis elegans function in the intestine and may act in drug transport. Genetics 172:885-892.
    • (2006) Genetics , vol.172 , pp. 885-892
    • Choy, R.K.1    Kemner, J.M.2    Thomas, J.H.3
  • 18
    • 0032483556 scopus 로고    scopus 로고
    • Natural variation in a neuropeptide Y receptor homolog modifies social behavior and food response in C. elegans
    • de Bono M, Bargmann CI. 1998. Natural variation in a neuropeptide Y receptor homolog modifies social behavior and food response in C. elegans. Cell 94:679-689.
    • (1998) Cell , vol.94 , pp. 679-689
    • De Bono, M.1    Bargmann, C.I.2
  • 19
    • 69849109122 scopus 로고    scopus 로고
    • Update on strategies to increase HDL quantity and function
    • Duffy D, Rader DJ. 2009. Update on strategies to increase HDL quantity and function. Nat Rev Cardiol 6:455-463.
    • (2009) Nat Rev Cardiol , vol.6 , pp. 455-463
    • Duffy, D.1    Rader, D.J.2
  • 20
    • 69649094479 scopus 로고    scopus 로고
    • Caenorhabditis elegans pheromones regulate multiple complex behaviors
    • Edison AS. 2009. Caenorhabditis elegans pheromones regulate multiple complex behaviors. Curr Opin Neurobiol 19:378-388.
    • (2009) Curr Opin Neurobiol , vol.19 , pp. 378-388
    • Edison, A.S.1
  • 21
    • 15944426129 scopus 로고    scopus 로고
    • Requirement of sterols in the life cycle of the nematode Caenorhabditis elegans
    • Entchev EV, Kurzchalia TV. 2005. Requirement of sterols in the life cycle of the nematode Caenorhabditis elegans. Semin Cell Dev Biol 16:175-182.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 175-182
    • Entchev, E.V.1    Kurzchalia, T.V.2
  • 23
    • 0035656274 scopus 로고    scopus 로고
    • A Hormonal Signaling Pathway Influencing C. elegans Metabolism, Reproductive Development, and Life Span
    • DOI 10.1016/S1534-5807(01)00085-5, PII S1534580701000855
    • Gerisch B, Weitzel C, Kober-Eisermann C, Rottiers V, Antebi A. 2001. A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. Dev Cell 1:841-851. (Pubitemid 33586137)
    • (2001) Developmental Cell , vol.1 , Issue.6 , pp. 841-851
    • Gerisch, B.1    Weitzel, C.2    Kober-Eisermann, C.3    Rottiers, V.4    Antebi, A.5
  • 25
    • 13844257281 scopus 로고    scopus 로고
    • Lipophilic regulator of a developmental switch in Caenorhabditis elegans
    • Gill MS, Held JM, Fisher AL, Gibson BW, Lithgow GJ. 2004. Lipophilic regulator of a developmental switch in Caenorhabditis elegans. Aging Cell 3:413-421.
    • (2004) Aging Cell , vol.3 , pp. 413-421
    • Gill, M.S.1    Held, J.M.2    Fisher, A.L.3    Gibson, B.W.4    Lithgow, G.J.5
  • 26
    • 0034192430 scopus 로고    scopus 로고
    • Nhr-25, the Caenorhabditis elegans ortholog of ftz-f1, is required for epidermal and somatic gonad development
    • Gissendanner CR, Sluder AE. 2000. nhr-25, the Caenorhabditis elegans ortholog of ftz-f1, is required for epidermal and somatic gonad development. Dev Biol 221:259-272.
    • (2000) Dev Biol , vol.221 , pp. 259-272
    • Gissendanner, C.R.1    Sluder, A.E.2
  • 27
    • 38449107943 scopus 로고    scopus 로고
    • Mechanosensation
    • Goodman MB. 2006. Mechanosensation. WormBook:1-14.
    • (2006) WormBook , pp. 1-14
    • Goodman, M.B.1
  • 28
    • 0032734242 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte
    • Grant B, Hirsh D. 1999. Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte. Mol Biol Cell 10:4311-4326.
    • (1999) Mol Biol Cell , vol.10 , pp. 4311-4326
    • Grant, B.1    Hirsh, D.2
  • 29
    • 6944250394 scopus 로고    scopus 로고
    • The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
    • Grigorenko AP, Moliaka YK, Soto MC, Mello CC, Rogaev EI. 2004. The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins. Proc Natl Acad Sci U S A 101:14955-14960.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14955-14960
    • Grigorenko, A.P.1    Moliaka, Y.K.2    Soto, M.C.3    Mello, C.C.4    Rogaev, E.I.5
  • 30
    • 38549152194 scopus 로고    scopus 로고
    • Principles of bioactive lipid signalling: Lessons from sphingolipids
    • Hannun YA, Obeid LM. 2008. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol 9:139-150.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 139-150
    • Hannun, Y.A.1    Obeid, L.M.2
  • 31
    • 0028898579 scopus 로고
    • Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans
    • Hara M, Han M. 1995. Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans. Proc Natl Acad Sci U S A 92:3333-3337.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3333-3337
    • Hara, M.1    Han, M.2
  • 32
    • 33746320419 scopus 로고    scopus 로고
    • DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid
    • DOI 10.1111/j.1474-9726.2006.00218.x
    • Held JM, White MP, Fisher AL, Gibson BW, Lithgow GJ, Gill MS. 2006. DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid. Aging Cell 5:283-291. (Pubitemid 44103243)
    • (2006) Aging Cell , vol.5 , Issue.4 , pp. 283-291
    • Held, J.M.1    White, M.P.2    Fisher, A.L.3    Gibson, B.W.4    Lithgow, G.J.5    Gill, M.S.6
  • 34
    • 38449105152 scopus 로고    scopus 로고
    • Dauer
    • Hu PJ. 2007. Dauer. WormBook:1-19.
    • (2007) WormBook , pp. 1-19
    • Hu, P.J.1
  • 37
    • 0036333147 scopus 로고    scopus 로고
    • DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity
    • Jia K, Albert PS, Riddle DL. 2002. DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity. Development 129:221-231.
    • (2002) Development , vol.129 , pp. 221-231
    • Jia, K.1    Albert, P.S.2    Riddle, D.L.3
  • 38
    • 65349113758 scopus 로고    scopus 로고
    • IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans
    • Jo H, Shim J, Lee JH, Lee J, Kim JB. 2009. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab 9:440-448.
    • (2009) Cell Metab , vol.9 , pp. 440-448
    • Jo, H.1    Shim, J.2    Lee, J.H.3    Lee, J.4    Kim, J.B.5
  • 39
    • 67650305511 scopus 로고    scopus 로고
    • Caenorhabditis elegans as an emerging model for studying the basic biology of obesity
    • Jones KT, Ashra. K. 2009. Caenorhabditis elegans as an emerging model for studying the basic biology of obesity. Dis Model Mech 2:224-229.
    • (2009) Dis Model Mech , vol.2 , pp. 224-229
    • Jones, K.T.1    Ashra, K.2
  • 40
    • 68749099747 scopus 로고    scopus 로고
    • Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis
    • Joo HJ, Yim YH, Jeong PY, Jin YX, Lee JE, Kim H, Jeong SK, Chitwood DJ, Paik YK. 2009. Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis. Biochem J 422:61-71.
    • (2009) Biochem J , vol.422 , pp. 61-71
    • Joo, H.J.1    Yim, Y.H.2    Jeong, P.Y.3    Jin, Y.X.4    Lee, J.E.5    Kim, H.6    Jeong, S.K.7    Chitwood, D.J.8    Paik, Y.K.9
  • 42
    • 0345305760 scopus 로고    scopus 로고
    • Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans
    • Kamikura DM, Cooper JA. 2003. Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans. Genes Dev 17:2798-2811.
    • (2003) Genes Dev , vol.17 , pp. 2798-2811
    • Kamikura, D.M.1    Cooper, J.A.2
  • 43
    • 2942598255 scopus 로고    scopus 로고
    • The effects of complex I function and oxidative damage on lifespan and anesthetic sensitivity in Caenorhabditis elegans
    • Kayser EB, Sedensky MM, Morgan PG. 2004. The effects of complex I function and oxidative damage on lifespan and anesthetic sensitivity in Caenorhabditis elegans. Mech Ageing Dev 125:455-464.
    • (2004) Mech Ageing Dev , vol.125 , pp. 455-464
    • Kayser, E.B.1    Sedensky, M.M.2    Morgan, P.G.3
  • 44
    • 0020724305 scopus 로고
    • Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans
    • Kimble J, Sharrock WJ. 1983. Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans. Dev Biol 96:189-196.
    • (1983) Dev Biol , vol.96 , pp. 189-196
    • Kimble, J.1    Sharrock, W.J.2
  • 45
    • 0037274642 scopus 로고    scopus 로고
    • Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans
    • Kniazeva M, Sieber M, McCauley S, Zhang K, Watts JL, Han M. 2003. Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans. Genetics 163:159-169.
    • (2003) Genetics , vol.163 , pp. 159-169
    • Kniazeva, M.1    Sieber, M.2    McCauley, S.3    Zhang, K.4    Watts, J.L.5    Han, M.6
  • 46
    • 19344363119 scopus 로고    scopus 로고
    • Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development
    • Kniazeva M, Crawford QT, Seiber M, Wang CY, Han M. 2004. Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development. PLoS Biol 2:E257.
    • (2004) PLoS Biol , vol.2
    • Kniazeva, M.1    Crawford, Q.T.2    Seiber, M.3    Wang, C.Y.4    Han, M.5
  • 47
    • 48949087618 scopus 로고    scopus 로고
    • A branched-chain fatty acid is involved in post-embryonic growth control in parallel to the insulin receptor pathway and its biosynthesis is feedback-regulated in C. elegans
    • Kniazeva M, Euler T, Han M. 2008. A branched-chain fatty acid is involved in post-embryonic growth control in parallel to the insulin receptor pathway and its biosynthesis is feedback-regulated in C. elegans. Genes Dev 22:2102-2110.
    • (2008) Genes Dev , vol.22 , pp. 2102-2110
    • Kniazeva, M.1    Euler, T.2    Han, M.3
  • 48
    • 0031832801 scopus 로고    scopus 로고
    • CHR3: A Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting
    • Kostrouchova M, Krause M, Kostrouch Z, Rall JE. 1998. CHR3: a Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting. Development 125:1617-1626.
    • (1998) Development , vol.125 , pp. 1617-1626
    • Kostrouchova, M.1    Krause, M.2    Kostrouch, Z.3    Rall, J.E.4
  • 49
    • 0035912840 scopus 로고    scopus 로고
    • Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans
    • Kostrouchova M, Krause M, Kostrouch Z, Rall JE. 2001. Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A 98:7360-7365.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 7360-7365
    • Kostrouchova, M.1    Krause, M.2    Kostrouch, Z.3    Rall, J.E.4
  • 51
    • 0344442921 scopus 로고    scopus 로고
    • The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans
    • Kuervers LM, Jones CL, O'Neil NJ, Baillie DL. 2003. The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans. Mol Genet Genomics 270:121-131.
    • (2003) Mol Genet Genomics , vol.270 , pp. 121-131
    • Kuervers, L.M.1    Jones, C.L.2    O'Neil, N.J.3    Baillie, D.L.4
  • 52
    • 0043198069 scopus 로고    scopus 로고
    • Why do worms need cholesterol?
    • Kurzchalia TV, Ward S. 2003. Why do worms need cholesterol? Nat Cell Biol 5:684-688.
    • (2003) Nat Cell Biol , vol.5 , pp. 684-688
    • Kurzchalia, T.V.1    Ward, S.2
  • 53
    • 65649122726 scopus 로고    scopus 로고
    • Lattices, rafts, and scaffolds: Domain regulation of receptor signaling at the plasma membrane
    • Lajoie P, Goetz JG, Dennis JW, Nabi IR. 2009. Lattices, rafts, and scaffolds: domain regulation of receptor signaling at the plasma membrane. J Cell Biol 185:381-385.
    • (2009) J Cell Biol , vol.185 , pp. 381-385
    • Lajoie, P.1    Goetz, J.G.2    Dennis, J.W.3    Nabi, I.R.4
  • 54
    • 54449091329 scopus 로고    scopus 로고
    • Early mitochondrial dysfunction in long-lived Mclk1+/- Mice
    • Lapointe J, Hekimi S. 2008. Early mitochondrial dysfunction in long-lived Mclk1+/- mice. J Biol Chem 283:26217-26227.
    • (2008) J Biol Chem , vol.283 , pp. 26217-26227
    • Lapointe, J.1    Hekimi, S.2
  • 55
    • 10344229417 scopus 로고    scopus 로고
    • NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways
    • Li J, Brown G, Ailion M, Lee S, Thomas JH. 2004. NCR-1 and NCR-2, the C. elegans homologs of the human Niemann-Pick type C1 disease protein, function upstream of DAF-9 in the dauer formation pathways. Development 131:5741-5752.
    • (2004) Development , vol.131 , pp. 5741-5752
    • Li, J.1    Brown, G.2    Ailion, M.3    Lee, S.4    Thomas, J.H.5
  • 57
    • 0034648768 scopus 로고    scopus 로고
    • Atherosclerosis
    • Lusis AJ. 2000. Atherosclerosis. Nature 407:233-241.
    • (2000) Nature , vol.407 , pp. 233-241
    • Lusis, A.J.1
  • 58
    • 4544296118 scopus 로고    scopus 로고
    • T-cell trafficking in asthma: Lipid mediators grease the way
    • Luster AD, Tager AM. 2004. T-cell trafficking in asthma: lipid mediators grease the way. Nat Rev Immunol 4: 711-724.
    • (2004) Nat Rev Immunol , vol.4 , pp. 711-724
    • Luster, A.D.1    Tager, A.M.2
  • 59
    • 0003042048 scopus 로고
    • Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits
    • Ma PT, Gil G, Sudhof TC, Bilheimer DW, Goldstein JL, Brown MS. 1986. Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits. Proc Natl Acad Sci U S A 83:8370-8374.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 8370-8374
    • Ma, P.T.1    Gil, G.2    Sudhof, T.C.3    Bilheimer, D.W.4    Goldstein, J.L.5    Brown, M.S.6
  • 61
    • 32544446633 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and neurotransmission in Caenorhabditis elegans
    • Marza E, Lesa GM. 2006. Polyunsaturated fatty acids and neurotransmission in Caenorhabditis elegans. Biochem Soc Trans 34:77-80.
    • (2006) Biochem Soc Trans , vol.34 , pp. 77-80
    • Marza, E.1    Lesa, G.M.2
  • 62
    • 41549169645 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling
    • Marza E, Long T, Saiardi A, Sumakovic M, Eimer S, Hall DH, Lesa GM. 2008. Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling. Mol Biol Cell 19:833-842.
    • (2008) Mol Biol Cell , vol.19 , pp. 833-842
    • Marza, E.1    Long, T.2    Saiardi, A.3    Sumakovic, M.4    Eimer, S.5    Hall, D.H.6    Lesa, G.M.7
  • 65
    • 28444476999 scopus 로고    scopus 로고
    • Membrane curvature and mechanisms of dynamic cell membrane remodelling
    • McMahon HT, Gallop JL. 2005. Membrane curvature and mechanisms of dynamic cell membrane remodelling. Nature 438:590-596.
    • (2005) Nature , vol.438 , pp. 590-596
    • McMahon, H.T.1    Gallop, J.L.2
  • 68
    • 58149339613 scopus 로고    scopus 로고
    • Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
    • Narbonne P, Roy R. 2009. Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457:210-214.
    • (2009) Nature , vol.457 , pp. 210-214
    • Narbonne, P.1    Roy, R.2
  • 70
    • 0042170293 scopus 로고    scopus 로고
    • SDF-9, a protein tyrosine phosphatase-like molecule, regulates the L3/dauer developmental decision through hormonal signaling in C. elegans
    • Ohkura K, Suzuki N, Ishihara T, Katsura I. 2003. SDF-9, a protein tyrosine phosphatase-like molecule, regulates the L3/dauer developmental decision through hormonal signaling in C. elegans. Development 130:3237-3248.
    • (2003) Development , vol.130 , pp. 3237-3248
    • Ohkura, K.1    Suzuki, N.2    Ishihara, T.3    Katsura, I.4
  • 71
    • 85047692761 scopus 로고    scopus 로고
    • Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production
    • Pan M, Cederbaum AI, Zhang YL, Ginsberg HN, Williams KJ, Fisher EA. 2004. Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production. J Clin Invest 113:1277-1287.
    • (2004) J Clin Invest , vol.113 , pp. 1277-1287
    • Pan, M.1    Cederbaum, A.I.2    Zhang, Y.L.3    Ginsberg, H.N.4    Williams, K.J.5    Fisher, E.A.6
  • 72
    • 65249110451 scopus 로고    scopus 로고
    • Caveolin-2 is required for apical lipid trafficking and suppresses basolateral recycling defects in the intestine of Caenorhabditis elegans
    • Parker S, Walker DS, Ly S, Baylis HA. 2009. Caveolin-2 is required for apical lipid trafficking and suppresses basolateral recycling defects in the intestine of Caenorhabditis elegans. Mol Biol Cell 20:1763-1771.
    • (2009) Mol Biol Cell , vol.20 , pp. 1763-1771
    • Parker, S.1    Walker, D.S.2    Ly, S.3    Baylis, H.A.4
  • 74
    • 48249142372 scopus 로고    scopus 로고
    • Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans
    • Patel DS, Fang LL, Svy DK, Ruvkun G, Li W. 2008. Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development in Caenorhabditis elegans. Development 135:2239-2249.
    • (2008) Development , vol.135 , pp. 2239-2249
    • Patel, D.S.1    Fang, L.L.2    Svy, D.K.3    Ruvkun, G.4    Li, W.5
  • 75
    • 16844382829 scopus 로고    scopus 로고
    • Pathological changes in acute coronary syndromes: The role of statin therapy in the modulation of inflammation, endothelial function and coagulation
    • Ray KK, Cannon CP. 2004. Pathological changes in acute coronary syndromes: the role of statin therapy in the modulation of inflammation, endothelial function and coagulation. J Thromb Thrombolysis 18:89-101.
    • (2004) J Thromb Thrombolysis , vol.18 , pp. 89-101
    • Ray, K.K.1    Cannon, C.P.2
  • 77
    • 0025879093 scopus 로고
    • Autonomy and nonautonomy of sex determination in triploid intersex mosaics of C. elegans
    • Schedin P, Hunter CP, Wood WB. 1991. Autonomy and nonautonomy of sex determination in triploid intersex mosaics of C. elegans. Development 112:863-879.
    • (1991) Development , vol.112 , pp. 863-879
    • Schedin, P.1    Hunter, C.P.2    Wood, W.B.3
  • 78
    • 0033147405 scopus 로고    scopus 로고
    • Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans
    • Scheel J, Srinivasan J, Honnert U, Henske A, Kurzchalia TV. 1999. Involvement of caveolin-1 in meiotic cell-cycle progression in Caenorhabditis elegans. Nat Cell Biol 1:127-129.
    • (1999) Nat Cell Biol , vol.1 , pp. 127-129
    • Scheel, J.1    Srinivasan, J.2    Honnert, U.3    Henske, A.4    Kurzchalia, T.V.5
  • 79
    • 65449137994 scopus 로고    scopus 로고
    • More than a signal: Non-signaling properties of quorum sensing molecules
    • Schertzer JW, Boulette ML, Whiteley M. 2009. More than a signal: non-signaling properties of quorum sensing molecules. Trends Microbiol 17:189-195.
    • (2009) Trends Microbiol , vol.17 , pp. 189-195
    • Schertzer, J.W.1    Boulette, M.L.2    Whiteley, M.3
  • 80
    • 70149098254 scopus 로고    scopus 로고
    • P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans
    • Seamen E, Blanchette JM, Han M. 2009. P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans. PLoS Genet 5:e1000589.
    • (2009) PLoS Genet , vol.5
    • Seamen, E.1    Blanchette, J.M.2    Han, M.3
  • 82
    • 0345600235 scopus 로고    scopus 로고
    • Redox regulation of germline and vulval development in Caenorhabditis elegans
    • Shibata Y, Branicky R, Landaverde IO, Hekimi S. 2003. Redox regulation of germline and vulval development in Caenorhabditis elegans. Science 302:1779-1782.
    • (2003) Science , vol.302 , pp. 1779-1782
    • Shibata, Y.1    Branicky, R.2    Landaverde, I.O.3    Hekimi, S.4
  • 83
    • 65249119361 scopus 로고    scopus 로고
    • Lipid mediators in health and disease: Enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation
    • Shimizu T. 2009. Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation. Annu Rev Pharmacol Toxicol 49:123-150.
    • (2009) Annu Rev Pharmacol Toxicol , vol.49 , pp. 123-150
    • Shimizu, T.1
  • 84
    • 5444251227 scopus 로고    scopus 로고
    • Identification of C. elegans DAF-12-binding sites, response elements, and target genes
    • Shostak Y, Van Gilst MR, Antebi A, Yamamoto KR. 2004. Identification of C. elegans DAF-12-binding sites, response elements, and target genes. Genes Dev 18:2529-2544.
    • (2004) Genes Dev , vol.18 , pp. 2529-2544
    • Shostak, Y.1    Van Gilst, M.R.2    Antebi, A.3    Yamamoto, K.R.4
  • 85
    • 18144363262 scopus 로고    scopus 로고
    • Current biology of MTP: Implications for selective inhibition
    • Shoulders CC, Shelness GS. 2005. Current biology of MTP: implications for selective inhibition. Curr Top Med Chem 5:283-300.
    • (2005) Curr Top Med Chem , vol.5 , pp. 283-300
    • Shoulders, C.C.1    Shelness, G.S.2
  • 86
    • 0037022349 scopus 로고    scopus 로고
    • Evidence of a mate-finding cue in the hermaphrodite nematode Caenorhabditis elegans
    • Simon JM, Sternberg PW. 2002. Evidence of a mate-finding cue in the hermaphrodite nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A 99:1598-1603.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1598-1603
    • Simon, J.M.1    Sternberg, P.W.2
  • 87
    • 34547844237 scopus 로고    scopus 로고
    • Human NPC1L1 and NPC1 can functionally substitute for the ncr genes to promote reproductive development in C. elegans
    • Smith MM, Levitan DJ. 2007. Human NPC1L1 and NPC1 can functionally substitute for the ncr genes to promote reproductive development in C. elegans. Biochim Biophys Acta 1770:1345-1351.
    • (2007) Biochim Biophys Acta , vol.1770 , pp. 1345-1351
    • Smith, M.M.1    Levitan, D.J.2
  • 88
    • 33947190010 scopus 로고    scopus 로고
    • Molecular diversity and evolution of the large lipid transfer protein superfamily
    • Smolenaars MM, Madsen O, Rodenburg KW, Van der Horst DJ. 2007. Molecular diversity and evolution of the large lipid transfer protein superfamily. J Lipid Res 48:489-502.
    • (2007) J Lipid Res , vol.48 , pp. 489-502
    • Smolenaars, M.M.1    Madsen, O.2    Rodenburg, K.W.3    Van Der Horst, D.J.4
  • 89
    • 0021855740 scopus 로고
    • The Caenorhabditis elegans vitellogenin gene family includes a gene encoding a distantly related protein
    • Spieth J, Blumenthal T. 1985. The Caenorhabditis elegans vitellogenin gene family includes a gene encoding a distantly related protein. Mol Cell Biol 5:2495-2501.
    • (1985) Mol Cell Biol , vol.5 , pp. 2495-2501
    • Spieth, J.1    Blumenthal, T.2
  • 91
    • 33751426642 scopus 로고    scopus 로고
    • Genetic and molecular characterization of CLK-1/mCLK1, a conserved determinant of the rate of aging
    • Stepanyan Z, Hughes B, Cliche DO, Camp D, Hekimi S. 2006. Genetic and molecular characterization of CLK-1/mCLK1, a conserved determinant of the rate of aging. Exp Gerontol 41:940-951.
    • (2006) Exp Gerontol , vol.41 , pp. 940-951
    • Stepanyan, Z.1    Hughes, B.2    Cliche, D.O.3    Camp, D.4    Hekimi, S.5
  • 93
    • 0034192462 scopus 로고    scopus 로고
    • A model for niemann-pick type C disease in the nematode Caenorhabditis elegans
    • Sym M, Basson M, Johnson C. 2000. A model for niemann-pick type C disease in the nematode Caenorhabditis elegans. Curr Biol 10:527-530.
    • (2000) Curr Biol , vol.10 , pp. 527-530
    • Sym, M.1    Basson, M.2    Johnson, C.3
  • 94
    • 33845969893 scopus 로고    scopus 로고
    • CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice
    • Uchiyama S, Shimizu T, Shirasawa T. 2006. CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice. J Biol Chem 281:31713-31719.
    • (2006) J Biol Chem , vol.281 , pp. 31713-31719
    • Uchiyama, S.1    Shimizu, T.2    Shirasawa, T.3
  • 95
    • 55849101681 scopus 로고    scopus 로고
    • Fat metabolism links germline stem cells and longevity in C. elegans
    • Wang MC, O'Rourke EJ, Ruvkun G. 2008. Fat metabolism links germline stem cells and longevity in C. elegans. Science 322:957-960.
    • (2008) Science , vol.322 , pp. 957-960
    • Wang, M.C.1    O'Rourke, E.J.2    Ruvkun, G.3
  • 96
    • 63749112313 scopus 로고    scopus 로고
    • Fat synthesis and adiposity regulation in Caenorhabditis elegans
    • Watts JL. 2009. Fat synthesis and adiposity regulation in Caenorhabditis elegans. Trends Endocrinol Metab 20:58-65.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 58-65
    • Watts, J.L.1
  • 97
    • 33645902496 scopus 로고    scopus 로고
    • Dietary manipulation implicates lipid signaling in the regulation of germ cell maintenance in C. elegans
    • Watts JL, Browse J. 2006. Dietary manipulation implicates lipid signaling in the regulation of germ cell maintenance in C. elegans. Dev Biol 292:381-392.
    • (2006) Dev Biol , vol.292 , pp. 381-392
    • Watts, J.L.1    Browse, J.2
  • 98
    • 0037298195 scopus 로고    scopus 로고
    • Deficiencies in C20 polyunsaturated fatty acids cause behavioral and developmental defects in Caenorhabditis elegans fat-3 mutants
    • Watts JL, Phillips E, Griffing KR, Browse J. 2003. Deficiencies in C20 polyunsaturated fatty acids cause behavioral and developmental defects in Caenorhabditis elegans fat-3 mutants. Genetics 163:581-589.
    • (2003) Genetics , vol.163 , pp. 581-589
    • Watts, J.L.1    Phillips, E.2    Griffing, K.R.3    Browse, J.4
  • 99
    • 37249016870 scopus 로고    scopus 로고
    • A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of longlived mitochondrial mutants of Caenorhabditis elegans
    • Yang W, Li J, Hekimi S. 2007. A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of longlived mitochondrial mutants of Caenorhabditis elegans. Genetics 177:2063-2074.
    • (2007) Genetics , vol.177 , pp. 2063-2074
    • Yang, W.1    Li, J.2    Hekimi, S.3
  • 100
    • 0033000965 scopus 로고    scopus 로고
    • A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting
    • Yochem J, Tuck S, Greenwald I, Han M. 1999. A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting. Development 126:597-606.
    • (1999) Development , vol.126 , pp. 597-606
    • Yochem, J.1    Tuck, S.2    Greenwald, I.3    Han, M.4


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