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Volumn 20, Issue 5, 2010, Pages 315-326

Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk

Author keywords

Colorectal adenoma; Diet; Gene environment interactions; Pharmacogenetics; Polymorphism; Xenobiotic metabolizing enzymes

Indexed keywords

ACYLTRANSFERASE; CYTOCHROME P450; CYTOCHROME P450 2C9; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); XENOBIOTIC AGENT;

EID: 77951499044     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3283395c6a     Document Type: Article
Times cited : (42)

References (72)
  • 1
    • 0028618531 scopus 로고
    • Epidemiology of colorectal adenomas
    • Peipins LA, Sandler RS. Epidemiology of colorectal adenomas. Epidemiol Rev 1994; 16:273-297.
    • (1994) Epidemiol Rev , vol.16 , pp. 273-297
    • Peipins, L.A.1    Sandler, R.S.2
  • 2
  • 9
    • 53349127456 scopus 로고    scopus 로고
    • Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer
    • Lightfoot TJ, Barrett JH, Bishop T, Northwood EL, Smith G, Wilkie MJ, et al. Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer. Cancer Epidemiol Biomarkers Prev 2008; 17:2421-2430.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2421-2430
    • Lightfoot, T.J.1    Barrett, J.H.2    Bishop, T.3    Northwood, E.L.4    Smith, G.5    Wilkie, M.J.6
  • 10
    • 3042783575 scopus 로고    scopus 로고
    • A critical review of the bioavailability of glucosinolates and related compounds
    • DOI 10.1039/b204039p
    • Holst B, Williamson G. A critical review of the bioavailability of glucosinolates and related compounds. Nat Prod Rep 2004; 21:425-447. (Pubitemid 38865722)
    • (2004) Natural Product Reports , vol.21 , Issue.3 , pp. 425-447
    • Holst, B.1    Williamson, G.2
  • 12
    • 60249083986 scopus 로고    scopus 로고
    • Fruit and vegetable intakes are associated with lower risk of colorectal adenomas
    • Wu H, Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Smalley WE, et al. Fruit and vegetable intakes are associated with lower risk of colorectal adenomas. J Nutr 2009; 139:340-344.
    • (2009) J Nutr , vol.139 , pp. 340-344
    • Wu, H.1    Dai, Q.2    Shrubsole, M.J.3    Ness, R.M.4    Schlundt, D.5    Smalley, W.E.6
  • 15
    • 0036847404 scopus 로고    scopus 로고
    • Effect of white versus red meat on endogenous N-nitrosation in the human colon and further evidence of a dose response
    • Bingham SA, Hughes R, Cross AJ. Effect of white versus red meat on endogenous N-nitrosation in the human colon and further evidence of a dose response. J Nutr 2002; 132:3522S-3525S. (Pubitemid 35315831)
    • (2002) Journal of Nutrition , vol.132 , Issue.11 SUPPL.
    • Bingham, S.A.1    Hughes, R.2    Cross, A.J.3
  • 16
    • 0038521317 scopus 로고    scopus 로고
    • Haem, not protein or inorganic iron, is responsible for endogenous intestinal N-nitrosation arising from red meat
    • Cross AJ, Pollock JR, Bingham SA. Haem, not protein or inorganic iron, is responsible for endogenous intestinal N-nitrosation arising from red meat. Cancer Res 2003; 63:2358-2360.
    • (2003) Cancer Res , vol.63 , pp. 2358-2360
    • Cross, A.J.1    Pollock, J.R.2    Bingham, S.A.3
  • 18
    • 0034056019 scopus 로고    scopus 로고
    • Nutrition and dietary carcinogens
    • Sugimura T. Nutrition and dietary carcinogens. Carcinogenesis 2000; 21:387-395. (Pubitemid 30137924)
    • (2000) Carcinogenesis , vol.21 , Issue.3 , pp. 387-395
    • Sugimura, T.1
  • 22
    • 77953637456 scopus 로고    scopus 로고
    • Lifestyle factors obesity and the risk of colorectal adenomas in EPIC-Heidelberg
    • [Epub ahead of print]
    • Hermann S, Rohrmann S, Linseisen J. Lifestyle factors, obesity and the risk of colorectal adenomas in EPIC-Heidelberg. Cancer Causes Control 2009 [Epub ahead of print]
    • (2009) Cancer Causes Control
    • Hermann, S.1    Rohrmann, S.2    Linseisen, J.3
  • 23
    • 70350020289 scopus 로고    scopus 로고
    • Gene-smoking interaction on colorectal adenoma and cancer risk: Review and meta-analysis
    • Raimondi S, Botteri E, Iodice S, Lowenfels AB, Maisonneuve P. Gene-smoking interaction on colorectal adenoma and cancer risk: review and meta-analysis. Mutat Res 2009; 670:6-14.
    • (2009) Mutat Res , vol.670 , pp. 6-14
    • Raimondi, S.1    Botteri, E.2    Iodice, S.3    Lowenfels, A.B.4    Maisonneuve, P.5
  • 24
    • 0025992864 scopus 로고
    • Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
    • Guengerich FP, Shimada T. Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chem Res Toxicol 1991; 4:391-407.
    • (1991) Chem Res Toxicol , vol.4 , pp. 391-407
    • Guengerich, F.P.1    Shimada, T.2
  • 28
    • 0027999623 scopus 로고
    • Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps
    • Lang NP, Butler MA, Massengill J, Lawson M, Stotts RC, Hauer-Jensen M, et al. Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps. Cancer Epidemiol Biomarkers Prev 1994; 3:675-682. (Pubitemid 24377961)
    • (1994) Cancer Epidemiology Biomarkers and Prevention , vol.3 , Issue.8 , pp. 675-682
    • Lang, N.P.1    Butler, M.A.2    Massengill, J.3    Lawson, M.4    Craig Stotts, R.5    Hauer-Jensen, M.6    Kadlubar, F.F.7
  • 29
    • 0030587544 scopus 로고    scopus 로고
    • Allelic variants of human cytochrome P450 2C9: Baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms
    • Haining RL, Hunter AP, Veronese ME, Trager WF, Rettie AE. Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms. Arch Biochem Biophys 1996; 333:447-458.
    • (1996) Arch Biochem Biophys , vol.333 , pp. 447-458
    • Haining, R.L.1    Hunter, A.P.2    Veronese, M.E.3    Trager, W.F.4    Rettie, A.E.5
  • 30
    • 7844247934 scopus 로고    scopus 로고
    • 359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes
    • DOI 10.1097/00008571-199810000-00001
    • Takahashi H, Kashima T, Nomoto S, Iwade K, Tainaka H, Shimizu T, et al. Comparisons between in-vitro and in-vivo metabolism of (S)-warfarin: catalytic activities of cDNA-expressed CYP2C9, its Leu359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes. Pharmacogenetics 1998; 8:365-373. (Pubitemid 28475300)
    • (1998) Pharmacogenetics , vol.8 , Issue.5 , pp. 365-373
    • Takahashi, H.1    Kashima, T.2    Nomoto, S.3    Iwade, K.4    Tainaka, H.5    Shimizu, T.6    Nomizo, Y.7    Muramoto, N.8    Kimura, S.9    Echizen, H.10
  • 31
    • 13544249943 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
    • DOI 10.1038/sj.tpj.6500285
    • Ingelman-Sundberg M. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J 2005; 5:6-13. (Pubitemid 40220611)
    • (2005) Pharmacogenomics Journal , vol.5 , Issue.1 , pp. 6-13
    • Ingelman-Sundberg, M.1
  • 32
    • 33747179265 scopus 로고    scopus 로고
    • Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology
    • DOI 10.2174/138920006778017786
    • Bolt HM, Thier R. Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology. Curr Drug Metab 2006; 7:613-628. (Pubitemid 44226589)
    • (2006) Current Drug Metabolism , vol.7 , Issue.6 , pp. 613-628
    • Bolt, H.M.1    Thier, R.2
  • 39
    • 0030888570 scopus 로고    scopus 로고
    • Pilot phase studies on the accuracy of dietary intake measurements in the EPIC project: Overall evaluation of results European prospective investigation into cancer and nutrition
    • Kaaks R, Slimani N, Riboli E. Pilot phase studies on the accuracy of dietary intake measurements in the EPIC project: overall evaluation of results. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 1997; 26 (Suppl 1):S26-S36.
    • (1997) Int J Epidemiol , vol.26 , Issue.SUPPL. 1
    • Kaaks, R.1    Slimani, N.2    Riboli, E.3
  • 40
    • 0030686545 scopus 로고    scopus 로고
    • United Kingdom women's cohort study steering group. Using crosscheck questions to address the problem of mis-reporting of specific food groups on food frequency questionnaires
    • Calvert C, Cade J, Barrett JH, Woodhouse A, UKWCS Steering Group. United Kingdom Women's Cohort Study Steering Group. Using crosscheck questions to address the problem of mis-reporting of specific food groups on Food Frequency Questionnaires. Eur J Clin Nutr 1997; 51:708-712.
    • (1997) Eur J Clin Nutr , vol.51 , pp. 708-712
    • Calvert, C.1    Cade, J.2    Barrett, J.H.3    Woodhouse, A.4
  • 41
    • 36549065804 scopus 로고    scopus 로고
    • Chemoprevention of colorectal cancer: Why all the confusion?
    • DOI 10.1097/MOG.0b013e3282f31d36, PII 0000157420080100000010
    • Bresalier RS. Chemoprevention of colorectal cancer: why all the confusion? Curr Opin Gastroenterol 2008; 24:48-50. (Pubitemid 350190897)
    • (2008) Current Opinion in Gastroenterology , vol.24 , Issue.1 , pp. 48-50
    • Bresalier, R.S.1
  • 42
    • 50149095987 scopus 로고    scopus 로고
    • Diet and cancer prevention: The roles of observation and experimentation
    • Martinez ME, Marshall JR, Giovannucci E. Diet and cancer prevention: the roles of observation and experimentation. Nat Rev Cancer 2008; 8:694-703.
    • (2008) Nat Rev Cancer , vol.8 , pp. 694-703
    • Martinez, M.E.1    Marshall, J.R.2    Giovannucci, E.3
  • 43
    • 0027370757 scopus 로고
    • Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer
    • Zhong S, Wyllie AH, Barnes D, Wolf CR, Spurr NK. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer. Carcinogenesis 1993; 14:1821-1824. (Pubitemid 23290894)
    • (1993) Carcinogenesis , vol.14 , Issue.9 , pp. 1821-1824
    • Zhong, S.1    Wyllie, A.H.2    Barnes, D.3    Wolf, C.R.4    Spurr, N.K.5
  • 44
    • 0035328829 scopus 로고    scopus 로고
    • CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk
    • Bigler J, Whitton J, Lampe JW, Fosdick L, Bostick RM, Potter JD. CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk. Cancer Res 2001; 61:3566-3569. (Pubitemid 32694961)
    • (2001) Cancer Research , vol.61 , Issue.9 , pp. 3566-3569
    • Bigler, J.1    Whitton, J.2    Lampe, J.W.3    Fosdick, L.4    Bostick, R.M.5    Potter, J.D.6
  • 45
    • 3543004770 scopus 로고    scopus 로고
    • A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma
    • Chan AT, Tranah GJ, Giovannucci EL, Hunter DJ, Fuchs CS. A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenoma. Clin Gastroenterol Hepatol 2004; 2:704-712.
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 704-712
    • Chan, A.T.1    Tranah, G.J.2    Giovannucci, E.L.3    Hunter, D.J.4    Fuchs, C.S.5
  • 47
    • 66149123253 scopus 로고    scopus 로고
    • Cytochrome P450 2C9 variants influence response to celecoxib for prevention of colorectal adenoma
    • e2121
    • Chan AT, Zauber AG, Hsu M, Breazna A, Hunter DJ, Rosenstein RB, et al. Cytochrome P450 2C9 variants influence response to celecoxib for prevention of colorectal adenoma. Gastroenterology 2009; 136:2127-2136. e2121.
    • (2009) Gastroenterology , vol.136 , pp. 2127-2136
    • Chan, A.T.1    Zauber, A.G.2    Hsu, M.3    Breazna, A.4    Hunter, D.J.5    Rosenstein, R.B.6
  • 48
    • 4143069198 scopus 로고    scopus 로고
    • CYP2C9 genotype as a predictor of drug disposition in humans
    • Lee CR. CYP2C9 genotype as a predictor of drug disposition in humans. Methods Find Exp Clin Pharmacol 2004; 26:463-472.
    • (2004) Methods Find Exp Clin Pharmacol , vol.26 , pp. 463-472
    • Lee, C.R.1
  • 49
    • 0027937066 scopus 로고
    • The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol
    • DOI 10.1002/mc.2940100307
    • Shou M, Korzekwa KR, Crespi CL, Gonzalez FJ, Gelboin HV. The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol. Mol Carcinog 1994; 10:159-168. (Pubitemid 24257511)
    • (1994) Molecular Carcinogenesis , vol.10 , Issue.3 , pp. 159-168
    • Shou, M.1    Korzekwa, K.R.2    Crespi, C.L.3    Gonzalez, F.J.4    Gelboin, H.V.5
  • 50
    • 70450245353 scopus 로고    scopus 로고
    • Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development
    • Zhou SF, Zhou ZW, Yang LP, Cai JP. Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem 2009; 16:3480-3675.
    • (2009) Curr Med Chem , vol.16 , pp. 3480-3675
    • Zhou, S.F.1    Zhou, Z.W.2    Yang, L.P.3    Cai, J.P.4
  • 53
    • 0034053367 scopus 로고    scopus 로고
    • The cytochrome P450 2D6 (CYP2D6) gene polymorphism among breast and head and neck cancer patients
    • DOI 10.1016/S0009-8981(00)00221-7, PII S0009898100002217
    • Topic E, Stefanovic M, Ivanisevic AM, Petrinovic R, Curcic I. The cytochrome P450 2D6 (CYP2D6) gene polymorphism among breast and head and neck cancer patients. Clin Chim Acta 2000; 296:101-109. (Pubitemid 30243143)
    • (2000) Clinica Chimica Acta , vol.296 , Issue.1-2 , pp. 101-109
    • Topic, E.1    Stefanovic, M.2    Ivanisevic, A.M.3    Petrinovic, R.4    Curcic, I.5
  • 55
    • 10044240625 scopus 로고    scopus 로고
    • Genetic polymorphisms of CYP2D6, GSTM1, and GSTT1 genes and bladder cancer risk in North India
    • DOI 10.1016/j.cancergencyto.2004.04.001, PII S0165460804001694
    • Sobti RC, Al-Badran AI, Sharma S, Sharma SK, Krishan A, Mohan H. Genetic polymorphisms of CYP2D6, GSTM1, and GSTT1 genes and bladder cancer risk in North India. Cancer Genet Cytogenet 2005; 156:68-73. (Pubitemid 39601062)
    • (2005) Cancer Genetics and Cytogenetics , vol.156 , Issue.1 , pp. 68-73
    • Sobti, R.C.1    Al-Badran, A.I.2    Sharma, S.3    Sharma, S.K.4    Krishan, A.5    Mohan, H.6
  • 57
    • 8844228173 scopus 로고    scopus 로고
    • Habitual consumption of fruits and vegetables: Associations with human rectal glutathione S-transferase
    • DOI 10.1093/carcin/bgh238
    • Wark PA, Grubben MJ, Peters WH, Nagengast FM, Kampman E, Kok FJ, et al. Habitual consumption of fruits and vegetables: associations with human rectal glutathione S-transferase. Carcinogenesis 2004; 25:2135-2142. (Pubitemid 39534850)
    • (2004) Carcinogenesis , vol.25 , Issue.11 , pp. 2135-2142
    • Wark, P.A.1    Grubben, M.J.A.L.2    Peters, W.H.M.3    Nagengast, F.M.4    Kampman, E.5    Kok, F.J.6    Van't Veer, P.7
  • 59
    • 0036955117 scopus 로고    scopus 로고
    • CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: Comparison with aromatic/hydrophobic adduct formation
    • DOI 10.1093/carcin/23.12.1969
    • Alexandrov K, Cascorbi I, Rojas M, Bouvier G, Kriek E, Bartsch H. CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. Carcinogenesis 2002; 23:1969-1977. (Pubitemid 36104950)
    • (2002) Carcinogenesis , vol.23 , Issue.12 , pp. 1969-1977
    • Alexandrov, K.1    Cascorbi, I.2    Rojas, M.3    Bouvier, G.4    Kriek, E.5    Bartsch, H.6
  • 60
    • 65449190487 scopus 로고    scopus 로고
    • Interindividual differences in response to plant-based diets: Implications for cancer risk
    • Lampe JW. Interindividual differences in response to plant-based diets: implications for cancer risk. Am J Clin Nutr 2009; 89:1553S-1557S.
    • (2009) Am J Clin Nutr , vol.89
    • Lampe, J.W.1
  • 63
    • 0028901808 scopus 로고
    • Glutathione transferase (GSTM1) null genotype, smoking, and prevalence of colorectal adenomas
    • Lin HJ, Probst-Hensch NM, Ingles SA, Han CY, Lin BK, Lee DB, et al. Glutathione transferase (GSTM1) null genotype, smoking, and prevalence of colorectal adenomas. Cancer Res 1995; 55:1224-1226.
    • (1995) Cancer Res , vol.55 , pp. 1224-1226
    • Lin, H.J.1    Probst-Hensch, N.M.2    Ingles, S.A.3    Han, C.Y.4    Lin, B.K.5    Lee, D.B.6
  • 64
    • 33845929583 scopus 로고    scopus 로고
    • Intervention with polyphenol-rich fruit juices results in an elevation of glutathione S-transferase P1 (hGSTP1) protein expression in human leucocytes of healthy volunteers
    • DOI 10.1002/mnfr.200600177
    • Hofmann T, Liegibel U, Winterhalter P, Bub A, Rechkemmer G, Pool-Zobel BL. Intervention with polyphenol-rich fruit juices results in an elevation of glutathione S-transferase P1 (hGSTP1) protein expression in human leucocytes of healthy volunteers. Mol Nutr Food Res 2006; 50:1191-1200. (Pubitemid 46032205)
    • (2006) Molecular Nutrition and Food Research , vol.50 , Issue.12 , pp. 1191-1200
    • Hofmann, T.1    Liegibel, U.2    Winterhalter, P.3    Bub, A.4    Rechkemmer, G.5    Pool-Zobel, B.L.6
  • 65
    • 34247621193 scopus 로고    scopus 로고
    • Effect of anthocyanin fractions from selected cultivars of Georgia-grown blueberries on apoptosis and phase II enzymes
    • DOI 10.1021/jf062915o
    • Srivastava A, Akoh CC, Fischer J, Krewer G. Effect of anthocyanin fractions from selected cultivars of Georgia-grown blueberries on apoptosis and phase II enzymes. J Agric Food Chem 2007; 55:3180-3185. (Pubitemid 46668332)
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , Issue.8 , pp. 3180-3185
    • Srivastava, A.1    Akoh, C.C.2    Fischer, J.3    Krewer, G.4
  • 66
    • 34047217405 scopus 로고    scopus 로고
    • Glutathione S-transferase phenotypes in relation to genetic variation and fruit and vegetable consumption in an endoscopy-based population
    • Tijhuis MJ, Visker MH, Aarts JM, Peters WH, Roelofs HM, den Camp LO, et al. Glutathione S-transferase phenotypes in relation to genetic variation and fruit and vegetable consumption in an endoscopy-based population. Carcinogenesis 2007; 28:848-857.
    • (2007) Carcinogenesis , vol.28 , pp. 848-857
    • Tijhuis, M.J.1    Visker, M.H.2    Aarts, J.M.3    Peters, W.H.4    Roelofs, H.M.5    Den Camp, L.O.6
  • 67
    • 0036848141 scopus 로고    scopus 로고
    • Meat consumption and meat preparation in relation to colorectal adenomas among sporadic and HNPCC family patients in NLD
    • DOI 10.1016/S0959-8049(02)00455-0, PII S0959804902004550
    • Voskuil DW, Kampman E, Grubben MJ, Kok FJ, Nagengast FM, Vasen HF, et al. Meat consumption and meat preparation in relation to colorectal adenomas among sporadic and HNPCC family patients in The Netherlands. Eur J Cancer 2002; 38:2300-2308. (Pubitemid 35346472)
    • (2002) European Journal of Cancer , vol.38 , Issue.17 , pp. 2300-2308
    • Voskuil, D.W.1    Kampman, E.2    Grubben, M.J.A.L.3    Kok, F.J.4    Nagengast, F.M.5    Vasen, H.F.A.6    Van 't Veer, P.7
  • 69
    • 0018866753 scopus 로고
    • False positive and negative hemoccult reactions on a normal diet and effect of diet restriction
    • Bassett ML, Goulston KJ. False positive and negative hemoccult reactions on a normal diet and effect of diet restriction. Aust N Z J Med 1980; 10:1-4.
    • (1980) Aust N Z J Med , vol.10 , pp. 1-4
    • Bassett, M.L.1    Goulston, K.J.2
  • 70
    • 0035866765 scopus 로고    scopus 로고
    • A case-control study of microsomal epoxide hydrolase, smoking, meat consumption, glutathione S-transferase M3, and risk of colorectal adenomas
    • Cortessis V, Siegmund K, Chen Q, Zhou N, Diep A, Frankl H, et al. A case-control study of microsomal epoxide hydrolase, smoking, meat consumption, glutathione S-transferase M3, and risk of colorectal adenomas. Cancer Res 2001; 61:2381-2385. (Pubitemid 32685809)
    • (2001) Cancer Research , vol.61 , Issue.6 , pp. 2381-2385
    • Cortessis, V.1    Siegmund, K.2    Chen, Q.3    Zhou, N.4    Diep, A.5    Frankl, H.6    Lee, E.7    Zhu, Q.-S.8    Haile, R.9    Levy, D.10
  • 72
    • 3242809821 scopus 로고    scopus 로고
    • Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Folow-up Study
    • DOI 10.1093/carcin/bgh126
    • Tranah GJ, Giovannucci E, Ma J, Fuchs C, Hankinson SE, Hunter DJ. Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up Study. Carcinogenesis 2004; 25:1211-1218. (Pubitemid 38968049)
    • (2004) Carcinogenesis , vol.25 , Issue.7 , pp. 1211-1218
    • Tranah, G.J.1    Giovannucci, E.2    Ma, J.3    Fuchs, C.4    Hankinson, S.E.5    Hunter, D.J.6


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