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Volumn 24, Issue 1, 2008, Pages 48-50

Chemoprevention of colorectal cancer: Why all the confusion?

Author keywords

Chemoprevention; Colorectal cancer; Fiber; Folate

Indexed keywords

ANTINEOPLASTIC AGENT; FOLIC ACID;

EID: 36549065804     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOG.0b013e3282f31d36     Document Type: Review
Times cited : (8)

References (13)
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    • Cole BF, Boron JA, Sandler RS, et al. Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA 2007; 297:2351-2359. Prospective randomized trial demonstrating that folic acid supplementation in patients with a previous history of colorectal adenomas does not reduce future colorectal adenoma risk, and in fact may increase the risk of colorectal neoplasia.
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    • Mason JB, Dickstein A, Jacques PF, et al. A temporal association between folic acid, fortification and an increase in colorectal cancer rates may be illuminating important biological principles: a hypothesis. Cancer Epidemiol Biomarkers Prev 2007; 16:1325-1329. This article asks the question 'Could dietary folic acid fortification alter the incidence of colorectal cancer in the population in an adverse fashion?'
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    • Baron JA, Sandler RS, Bresalier RS, et al. A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. Gastroenterology 2006; 131:1674-1682. This prospective randomized trial demonstrates a significant reduction in new adenomas in individuals taking a cyclooxygenase-2 inhibitor compared with placebo, but with an increased risk of adverse cardiovascular and gastrointestinal events.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.