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Volumn 61, Issue 3, 2010, Pages 324-336

Effects of phenylethyl isothiocyanate and its metabolite on cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells

Author keywords

Apoptosis; Cell cycle; N acetylcysteine conjugate; Phenylethyl isothiocyanate; Prostate cancer

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; GLUCONASTURTIIN; GLUCOSINOLATE; ISOTHIOCYANIC ACID DERIVATIVE; PHENETHYL ISOTHIOCYANATE; PLANT EXTRACT;

EID: 77951496270     PISSN: 09637486     EISSN: 14653478     Source Type: Journal    
DOI: 10.3109/09637481003639092     Document Type: Article
Times cited : (31)

References (36)
  • 1
    • 1442347508 scopus 로고    scopus 로고
    • American Cancer Society., Atlanta, GA: National Home Office
    • American Cancer Society. 2004. Cancer facts and figures. Atlanta, GA: National Home Office. pp 1-56.
    • (2004) Cancer Facts and Figures , pp. 1-56
  • 2
    • 33646816025 scopus 로고    scopus 로고
    • Bisphosphonate induces apoptosis and inhibits pro-osteoclastic gene expression in prostate cancer cells
    • Asahi H, Mizokami A, Miwa S, Keller ET, Koshida K, Namiki M. 2006. Bisphosphonate induces apoptosis and inhibits pro-osteoclastic gene expression in prostate cancer cells. Int J Urol 13:593-600.
    • (2006) Int J Urol , vol.13 , pp. 593-600
    • Asahi, H.1    Mizokami, A.2    Miwa, S.3    Keller, E.T.4    Koshida, K.5    Namiki, M.6
  • 3
    • 33746268096 scopus 로고    scopus 로고
    • Cytostatic activity of paclitaxel in coronary artery smooth muscle cells is mediated through transient mitotic arrest followed by permanent post-mitotic arrest: Comparison with cancer cells
    • Blagosklonny MV, Demidenko ZN, Giovino M, Szynal C, Donskoy E, Herrmann RA, Barry JJ, Whalen AM. 2006. Cytostatic activity of paclitaxel in coronary artery smooth muscle cells is mediated through transient mitotic arrest followed by permanent post-mitotic arrest: Comparison with cancer cells. Cell Cycle 5:1574-1579.
    • (2006) Cell Cycle , vol.5 , pp. 1574-1579
    • Blagosklonny, M.V.1    Demidenko, Z.N.2    Giovino, M.3    Szynal, C.4    Donskoy, E.5    Herrmann, R.A.6    Barry, J.J.7    Whalen, A.M.8
  • 4
    • 65949086045 scopus 로고    scopus 로고
    • Atg5 regulates phenethyl isothiocyanate-induced autophagic and apototic cell death in human prostate cancer cells
    • Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, Jiang Y, Singh SV. 2009. Atg5 regulates phenethyl isothiocyanate-induced autophagic and apototic cell death in human prostate cancer cells. Cancer Res 69:3704-3712.
    • (2009) Cancer Res , vol.69 , pp. 3704-3712
    • Bommareddy, A.1    Hahm, E.R.2    Xiao, D.3    Powolny, A.A.4    Fisher, A.L.5    Jiang, Y.6    Singh, S.V.7
  • 5
    • 33644675196 scopus 로고    scopus 로고
    • Role of diet in prostate cancer development and progression
    • Chan JM, Gann PH, Giovannucci EL. 2005. Role of diet in prostate cancer development and progression. J Clin Oncol 23:8152-8160.
    • (2005) J Clin Oncol , vol.23 , pp. 8152-8160
    • Chan, J.M.1    Gann, P.H.2    Giovannucci, E.L.3
  • 6
    • 0037131419 scopus 로고    scopus 로고
    • Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase
    • Chen YR, Han J, Kori R, Kong AN, Tan TH. 2002. Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase. J Biol Chem 277:39334-39342.
    • (2002) J Biol Chem , vol.277 , pp. 39334-39342
    • Chen, Y.R.1    Han, J.2    Kori, R.3    Kong, A.N.4    Tan, T.H.5
  • 7
    • 0034202404 scopus 로고    scopus 로고
    • Modulation of growth of human prostate cancer cells by the N-acetylcysteine conjugate of phenethyl isothiocyanate
    • Chiao JW, Chung F, Krzeminski J, Amin S, Arshad R, Ahmed T, Conaway CC. 2000. Modulation of growth of human prostate cancer cells by the N-acetylcysteine conjugate of phenethyl isothiocyanate. Int J Oncol 16:1215-1219.
    • (2000) Int J Oncol , vol.16 , pp. 1215-1219
    • Chiao, J.W.1    Chung, F.2    Krzeminski, J.3    Amin, S.4    Arshad, R.5    Ahmed, T.6    Conaway, C.C.7
  • 9
    • 0035987188 scopus 로고    scopus 로고
    • Isothiocyanates as cancer chemo-preventive agents: Their biological activities and metabolism in rodents and humans
    • Conaway CC, Yang YM, Chung FL. 2002. Isothiocyanates as cancer chemo-preventive agents: Their biological activities and metabolism in rodents and humans. Curr Drug Metab 3:233-255.
    • (2002) Curr Drug Metab , vol.3 , pp. 233-255
    • Conaway, C.C.1    Yang, Y.M.2    Chung, F.L.3
  • 10
    • 24944480252 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogenesis in A/J mice
    • Conaway CC, Wang CX, Pittman B, Yang YM, Schwartz JE, Tian D, Mclntee EJ, Hecht SS, Chung FL. 2005. Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogenesis in A/J mice. Cancer Res 65:8548-8557.
    • (2005) Cancer Res , vol.65 , pp. 8548-8557
    • Conaway, C.C.1    Wang, C.X.2    Pittman, B.3    Yang, Y.M.4    Schwartz, J.E.5    Tian, D.6    McLntee, E.J.7    Hecht, S.S.8    Chung, F.L.9
  • 11
    • 0032512820 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibits the expression of cyclin dependent kinase 6 and induce a G1 cell cycle arrest of human cancer cells independent of estrogen receptor signaling
    • Cover CM, Hsieh SJ, Tran SH, Hallden G, Kim GS, Bjeldanes LF, Firestone GL. 1998. Indole-3-carbinol inhibits the expression of cyclin dependent kinase 6 and induce a G1 cell cycle arrest of human cancer cells independent of estrogen receptor signaling. J Biol Chem 273:3838-3847.
    • (1998) J Biol Chem , vol.273 , pp. 3838-3847
    • Cover, C.M.1    Hsieh, S.J.2    Tran, S.H.3    Hallden, G.4    Kim, G.S.5    Bjeldanes, L.F.6    Firestone, G.L.7
  • 15
    • 33645283870 scopus 로고    scopus 로고
    • BID as a double agent in cell life and death
    • Gross A. 2006. BID as a double agent in cell life and death. Cell Cycle 5:582-584.
    • (2006) Cell Cycle , vol.5 , pp. 582-584
    • Gross, A.1
  • 16
    • 0141888260 scopus 로고    scopus 로고
    • Evaluation of urinary N-acetyl cysteinyl allyl isothiocyanate as a biomarker for intake and bioactivity of Brussels sprouts
    • Hwang E, Jeffery EH. 2003. Evaluation of urinary N-acetyl cysteinyl allyl isothiocyanate as a biomarker for intake and bioactivity of Brussels sprouts. Food Chem Toxicol 41:1817-1825.
    • (2003) Food Chem Toxicol , vol.41 , pp. 1817-1825
    • Hwang, E.1    Jeffery, E.H.2
  • 17
    • 33751116940 scopus 로고    scopus 로고
    • Phenylethyl isothiocyanate and its N-acetylcysteine conjugate suppress the metastasis of SK-Hep1 human hepatoma cells
    • Hwang E, Lee HJ. 2006. Phenylethyl isothiocyanate and its N-acetylcysteine conjugate suppress the metastasis of SK-Hep1 human hepatoma cells. J Nutr Biochem 17:837-846.
    • (2006) J Nutr Biochem , vol.17 , pp. 837-846
    • Hwang, E.1    Lee, H.J.2
  • 18
    • 33644659892 scopus 로고    scopus 로고
    • Effects of MEK1 and PI3K inhibitors on allyl-, benzyl- and phenylethyl-isothiocyanate-induced G2/M arrest and cell death in Caco-2 cells
    • Jakubikova J, Sedlak J, Bacon J, Goldson A, Bao Y. 2005. Effects of MEK1 and PI3K inhibitors on allyl-, benzyl- and phenylethyl-isothiocyanate-induced G2/M arrest and cell death in Caco-2 cells. Int J Oncol 27:1449-1458.
    • (2005) Int J Oncol , vol.27 , pp. 1449-1458
    • Jakubikova, J.1    Sedlak, J.2    Bacon, J.3    Goldson, A.4    Bao, Y.5
  • 19
    • 0036149122 scopus 로고    scopus 로고
    • Attenuation of tubular apoptosis by blockade of the rennin-angiotensin system in diabetic Ren-2 rats
    • Kelly DJ, Cox AJ, Tolcos M, Cooper ME, Wikinson-Berka JL, Gilbert RE. 2002. Attenuation of tubular apoptosis by blockade of the rennin-angiotensin system in diabetic Ren-2 rats. Kidney Int 61:31-39.
    • (2002) Kidney Int , vol.61 , pp. 31-39
    • Kelly, D.J.1    Cox, A.J.2    Tolcos, M.3    Cooper, M.E.4    Wikinson-Berka, J.L.5    Gilbert, R.E.6
  • 20
    • 3142710318 scopus 로고    scopus 로고
    • Cruciferous vegetables and prostate cancer risk: Confounding by PSA screening
    • Kristal AR, Stanford JL. 2004. Cruciferous vegetables and prostate cancer risk: Confounding by PSA screening. Cancer Epidemiol. Biomarkers Prev 13:1265.
    • (2004) Cancer Epidemiol. Biomarkers Prev , vol.13 , pp. 1265
    • Kristal, A.R.1    Stanford, J.L.2
  • 21
  • 23
    • 33644858631 scopus 로고    scopus 로고
    • CDK activation by non-cyclin proteins
    • Nebreda AR. 2006. CDK activation by non-cyclin proteins. Curr Opin Cell Biol 18:192-198.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 192-198
    • Nebreda, A.R.1
  • 25
    • 33644830944 scopus 로고    scopus 로고
    • Targeting the cell cycle: A new approach to cancer therapy
    • Schwartz GK, Shah MA. 2005. Targeting the cell cycle: A new approach to cancer therapy. J Clin Oncol 23:9408-9421.
    • (2005) J Clin Oncol , vol.23 , pp. 9408-9421
    • Schwartz, G.K.1    Shah, M.A.2
  • 26
    • 33645802169 scopus 로고    scopus 로고
    • Cyclin-dependent kinase pathways as targets for cancer treatment
    • Shapiro GI. 2006. Cyclin-dependent kinase pathways as targets for cancer treatment. J Clin Oncol 24: 1770-1783.
    • (2006) J Clin Oncol , vol.24 , pp. 1770-1783
    • Shapiro, G.I.1
  • 27
    • 0036581949 scopus 로고    scopus 로고
    • Phytochemicals as cell cycle modulators: A less toxic approach in halting human cancer
    • Singh RP. Dhanakakshmi S, Agarwal R. 2002. Phytochemicals as cell cycle modulators: A less toxic approach in halting human cancer. Cell Cycle 1:156-161.
    • (2002) Cell Cycle , vol.1 , pp. 156-161
    • Singh, R.P.1    Dhanakakshmi, S.2    Agarwal, R.3
  • 28
    • 4544311831 scopus 로고    scopus 로고
    • Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells
    • Srivastava SK, Singh SV. 2004. Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells. Carcinogenesis 25:1701-1709.
    • (2004) Carcinogenesis , vol.25 , pp. 1701-1709
    • Srivastava, S.K.1    Singh, S.V.2
  • 29
    • 33644928489 scopus 로고    scopus 로고
    • BCL2 family of apoptosis-regulated genes: Functions and clinical implications in cancer
    • Thomadaki H, Scorilas A. 2006. BCL2 family of apoptosis-regulated genes: Functions and clinical implications in cancer. Crit Rev Clin Lab Sci 43:1-67.
    • (2006) Crit Rev Clin Lab Sci , vol.43 , pp. 1-67
    • Thomadaki, H.1    Scorilas, A.2
  • 30
    • 7944237475 scopus 로고    scopus 로고
    • Dietary isothiocyanates inhibit Caco-2 cell proliferation and induce G2/M phase cell cycle arrest, DNA damage, and G2/M checkpoint activation
    • Visaniji JM, Duthie SJ, Pirie L, Thompson DG, Padfield PJ. 2004. Dietary isothiocyanates inhibit Caco-2 cell proliferation and induce G2/M phase cell cycle arrest, DNA damage, and G2/M checkpoint activation. J Nutr 134:3121-3126.
    • (2004) J Nutr , vol.134 , pp. 3121-3126
    • Visaniji, J.M.1    Duthie, S.J.2    Pirie, L.3    Thompson, D.G.4    Padfield, P.J.5
  • 32
    • 1642460754 scopus 로고    scopus 로고
    • Angiotensin II and cell cycle regulation
    • Wolf G, Wenzel UO. 2004. Angiotensin II and cell cycle regulation. Hypertention 43:693-698.
    • (2004) Hypertention , vol.43 , pp. 693-698
    • Wolf, G.1    Wenzel, U.O.2
  • 33
    • 0037972262 scopus 로고    scopus 로고
    • Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis
    • Xiao D, Srivastava SK, Lew KL, Zeng Y, Hershberger P, Johnson CS, Trump DL, Singh SV. 2003. Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis. Carcinogenesis 24:891-897.
    • (2003) Carcinogenesis , vol.24 , pp. 891-897
    • Xiao, D.1    Srivastava, S.K.2    Lew, K.L.3    Zeng, Y.4    Hershberger, P.5    Johnson, C.S.6    Trump, D.L.7    Singh, S.V.8
  • 34
    • 21744455695 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells
    • Xiao D, Choi S, Lee YJ, Singh SV. 2005. Role of mitogen-activated protein kinases in phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells. Mol Carcinog 43:130-140.
    • (2005) Mol Carcinog , vol.43 , pp. 130-140
    • Xiao, D.1    Choi, S.2    Lee, Y.J.3    Singh, S.V.4
  • 35
    • 1942534018 scopus 로고    scopus 로고
    • Regulation of apoptosis proteins in cancer cells by ubiquitin
    • Zhang HG, Wang J, Yang X, Hsu HC, Mountz JD. 2004. Regulation of apoptosis proteins in cancer cells by ubiquitin. Oncogene 23:2009-2015.
    • (2004) Oncogene , vol.23 , pp. 2009-2015
    • Zhang, H.G.1    Wang, J.2    Yang, X.3    Hsu, H.C.4    Mountz, J.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.