Interaction of biodegradable nanoparticles with intestinal cells: The effect of surface hydrophilicity

International Journal of Pharmaceutics

Volumn 390, Issue 1, 2010, Pages 45-52

  Gaumet, M ^a,b   Gurny, R ^a   Delie, F ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Biodegradable polymers; Caco 2 cells; Cellular uptake; Chitosan; Fluorescence spectroscopy; Nanoparticles; Surface hydrophilicity

Indexed keywords

CHITOSAN; FLUORESCENT DYE; NANOPARTICLE; POLYGLACTIN; POLYMER; 3,3'-DIOCTADECYLOXACARBOCYANINE; BIOMATERIAL; CARBOCYANINE; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ADSORPTION; APICAL MEMBRANE; ARTICLE; BIODEGRADABILITY; CELL NUCLEUS; CELL STRAIN CACO 2; CELLULAR DISTRIBUTION; CENTRIFUGATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EMULSION; EVAPORATION; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; HYDROPHILICITY; INTESTINE CELL; MOLECULAR INTERACTION; PARTICLE SIZE; PRIORITY JOURNAL; CACO 2 CELL LINE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; FLUORESCENCE MICROSCOPY; INTESTINE MUCOSA; INTRACELLULAR SPACE; METABOLISM; SCANNING ELECTRON MICROSCOPY; STATIC ELECTRICITY; SURFACE PROPERTY;

BIOCOMPATIBLE MATERIALS; CACO-2 CELLS; CARBOCYANINES; CELL SURVIVAL; CHITOSAN; FLUORESCENT DYES; HUMANS; INTESTINAL MUCOSA; INTRACELLULAR SPACE; LACTIC ACID; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; NANOPARTICLES; PARTICLE SIZE; POLYGLYCOLIC ACID; STATIC ELECTRICITY; SURFACE PROPERTIES;

EID: 77951257204     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.10.008     Document Type: Article

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