Transfer of lipophilic markers from PLGA and polystyrene nanoparticles to Caco-2 monolayers mimics particle uptake

Pharmaceutical Research

Volumn 19, Issue 5, 2002, Pages 595-601

  Pietzonka, P ^a,b   Rothen Rutishauser, B ^a   Langguth, P ^c   Wunderli Allenspach, H ^a   Walter, E ^a   Merkle, H P ^a  

^a ETH ZURICH   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Caco 2 cells; Drug release; Fluorescence; Nanoparticle; Particle uptake

Indexed keywords

LIPOSOME; NANOPARTICLE; POLYGLACTIN; POLYSTYRENE; FLUORESCENT DYE; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER; POLYSTYRENE DERIVATIVE;

ARTICLE; CELL LABELING; CELLULAR DISTRIBUTION; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DIFFUSION; DISPERSION; EVALUATION; FLUORESCENCE; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LIPOPHILICITY; MOLECULAR MIMICRY; PHASE SEPARATION; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; TRANSPORT KINETICS; CELL STRAIN CACO 2; IN VITRO STUDY; METABOLISM; NANOTECHNOLOGY; PARTICLE SIZE; PERMEABILITY; SCANNING ELECTRON MICROSCOPY; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CACO-2 CELLS; DIFFUSION; FLUORESCENT DYES; HUMAN; IN VITRO; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; NANOTECHNOLOGY; PARTICLE SIZE; PERMEABILITY; POLYGLYCOLIC ACID; POLYMERS; POLYSTYRENES; SUPPORT, NON-U.S. GOV'T; HUMANS;

EID: 0036001389     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015393710253     Document Type: Article

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