-
1
-
-
57549097072
-
Autophagy: A target for therapeutic interventions in myocardial pathophysiology
-
Halapas A, Armakolas A, Koutsilieris M. Autophagy: a target for therapeutic interventions in myocardial pathophysiology. Expert Opin Ther Targets 2008;12:1509-1522
-
(2008)
Expert Opin Ther Targets
, vol.12
, pp. 1509-1522
-
-
Halapas, A.1
Armakolas, A.2
Koutsilieris, M.3
-
2
-
-
48149111341
-
Gamma-IFN-induciblelysosomal thiol reductase modulates acidic proteases and HLA class II antigen processing in melanoma
-
Goldstein OG, Hajiaghamohseni LM, Amria S, et al. Gamma-IFN- induciblelysosomal thiol reductase modulates acidic proteases and HLA class II antigen processing in melanoma. Cancer Immunol Immunother 2008;57:1461-1470
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1461-1470
-
-
Goldstein, O.G.1
Hajiaghamohseni, L.M.2
Amria, S.3
-
3
-
-
52949091163
-
Zinc signalling and subcellular distribution: Emerging targets in type 2 diabetes
-
Mocchegiani E, Giacconi R, Malavolta M. Zinc signalling and subcellular distribution: emerging targets in type 2 diabetes. Trends Mol Med 2008;14:419-428
-
(2008)
Trends Mol Med
, vol.14
, pp. 419-428
-
-
Mocchegiani, E.1
Giacconi, R.2
Malavolta, M.3
-
4
-
-
35648950010
-
New concepts in antimalarial use and mode of action in dermatology
-
Kalia S, Dutz JP. New concepts in antimalarial use and mode of action in dermatology. Dermatol Ther 2007;20:160-174
-
(2007)
Dermatol Ther
, vol.20
, pp. 160-174
-
-
Kalia, S.1
Dutz, J.P.2
-
5
-
-
73449120372
-
Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: A systematic review
-
Ruiz-Irastorza G, Ramos-Casals M, Brito-Zeron P, Khamashta MA. Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review. Ann Rheum Dis 2010;69:20-28
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 20-28
-
-
Ruiz-Irastorza, G.1
Ramos-Casals, M.2
Brito-Zeron, P.3
Khamashta, M.A.4
-
6
-
-
0016255812
-
Protein degradation in cultured cells.II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1
-
Wibo M, Poole B. Protein degradation in cultured cells.II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1. J Cell Biol 1974;63:430-440
-
(1974)
J Cell Biol
, vol.63
, pp. 430-440
-
-
Wibo, M.1
Poole, B.2
-
7
-
-
4243052029
-
Chloroquine blood concentrations and molecular markers of chloroquine-resistant Plasmodium falciparum in febrile children in northern Ghana
-
Ehrhardt S, Mockenhaupt FP, Eggelte TA, et al. Chloroquine blood concentrations and molecular markers of chloroquine-resistant Plasmodium falciparum in febrile children in northern Ghana. Trans R Soc Trop Med Hyg 2003;97:697-701
-
(2003)
Trans R Soc Trop Med Hyg
, vol.97
, pp. 697-701
-
-
Ehrhardt, S.1
Mockenhaupt, F.P.2
Eggelte, T.A.3
-
8
-
-
9144224186
-
Hydroxychloroquine for the prevention of acute graft-versus-host disease after unrelated donor transplantation
-
Khoury H, Trinkaus K, Zhang MJ, et al. Hydroxychloroquine for the prevention of acute graft-versus-host disease after unrelated donor transplantation. Biol Blood Marrow Transplant 2003;9:714-721
-
(2003)
Biol Blood Marrow Transplant
, vol.9
, pp. 714-721
-
-
Khoury, H.1
Trinkaus, K.2
Zhang, M.J.3
-
10
-
-
39449101201
-
Hypoglycaemia induced by hydroxychloroquine in a non-diabetic patient treated for RA
-
Cansu DU, Korkmaz C. Hypoglycaemia induced by hydroxychloroquine in a non-diabetic patient treated for RA. Rheumatology 2008;47:378-379
-
(2008)
Rheumatology
, vol.47
, pp. 378-379
-
-
Cansu, D.U.1
Korkmaz, C.2
-
11
-
-
0036175209
-
The effectiveness of hydroxychloroquine in patients with type 2 diabetes mellitus who are refractory to sulfonylureas-a randomized trial
-
Gerstein HC, Thorpe KE, Taylor DW, Haynes RB. The effectiveness of hydroxychloroquine in patients with type 2 diabetes mellitus who are refractory to sulfonylureas-a randomized trial. Diabetes Res Clin Pract 2002;55:209-219
-
(2002)
Diabetes Res Clin Pract
, vol.55
, pp. 209-219
-
-
Gerstein, H.C.1
Thorpe, K.E.2
Taylor, D.W.3
Haynes, R.B.4
-
12
-
-
0033224414
-
Effects of chloroquine on insulin sensitivity in insulin-resistant rats
-
Li C, Zhang S, Shu C. Effects of chloroquine on insulin sensitivity in insulin-resistant rats. Zhonghua Yi Xue Za Zhi Natl Med J China 1999;79:867-869
-
(1999)
Zhonghua Yi Xue Za Zhi Natl Med J China
, vol.79
, pp. 867-869
-
-
Li, C.1
Zhang, S.2
Shu, C.3
-
13
-
-
0029990745
-
Hydroxychloroquine use in the Baltimore Lupus Cohort: Effects on lipids, glucose and thrombosis
-
Petri M. Hydroxychloroquine use in the Baltimore Lupus Cohort: effects on lipids, glucose and thrombosis. Lupus Suppl 1996;1:S16-22
-
(1996)
Lupus Suppl
, vol.1
-
-
Petri, M.1
-
14
-
-
0027481309
-
Effects of chloroquine on the dyslipidemia of non-insulin dependent diabetes mellitus
-
Powrie JK, Shojaee-Moradic F, Watts GF, et al. Effects of chloroquine on the dyslipidemia of non-insulin dependent diabetes mellitus. Metabolism 1993;42:415-419
-
(1993)
Metabolism
, vol.42
, pp. 415-419
-
-
Powrie, J.K.1
Shojaee-Moradic, F.2
Watts, G.F.3
-
15
-
-
0032892589
-
Hypoglycemia induced by hydroxychloroquine in a type 2 diabetic treated for polyarthritis
-
Shojana K, Koehler BF, Elliot T. Hypoglycemia induced by hydroxychloroquine in a type 2 diabetic treated for polyarthritis. J Rheumatol 1999;1:195-196
-
(1999)
J Rheumatol
, vol.1
, pp. 195-196
-
-
Shojana, K.1
Koehler, B.F.2
Elliot, T.3
-
16
-
-
0030011150
-
The use of chloroquine and hydroxychloroquine for non-infectious diseases other than rheumatoid arthritis or lupus: A critical review
-
Wallace DJ. The use of chloroquine and hydroxychloroquine for non-infectious diseases other than rheumatoid arthritis or lupus: a critical review. Lupus Suppl 1996;1:S59-64
-
(1996)
Lupus Suppl
, vol.1
-
-
Wallace, D.J.1
-
18
-
-
43049156331
-
Cardiovascular risk in rheumatoid arthritis: Effects of anti-TNF drugs
-
Avouac J, Allanore Y. Cardiovascular risk in rheumatoid arthritis: effects of anti-TNF drugs. Expert Opin Pharmacother 2008;9:1121-1128
-
(2008)
Expert Opin Pharmacother
, vol.9
, pp. 1121-1128
-
-
Avouac, J.1
Allanore, Y.2
-
19
-
-
42649134835
-
The implication of proinflammatory cytokines in type 2 diabetes
-
Guest CB, Park MJ, Johnson DR, Freund GG. The implication of proinflammatory cytokines in type 2 diabetes. Front Biosci 2008;13:5187-5194
-
(2008)
Front Biosci
, vol.13
, pp. 5187-5194
-
-
Guest, C.B.1
Park, M.J.2
Johnson, D.R.3
Freund, G.G.4
-
20
-
-
47149096915
-
Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity
-
Heilbronn LK, Campbell LV. Adipose tissue macrophages, low grade inflammation and insulin resistance in human obesity. Curr Pharm Des 2008;14:1225-1230
-
(2008)
Curr Pharm des
, vol.14
, pp. 1225-1230
-
-
Heilbronn, L.K.1
Campbell, L.V.2
-
21
-
-
58149092981
-
Autophagy and acute pancreatitis: A novel autophagy theory for trypsinogen activation
-
Ohmuraya M, Yamamura K. Autophagy and acute pancreatitis: a novel autophagy theory for trypsinogen activation. Autophagy 2008;4:1060-1062
-
(2008)
Autophagy
, vol.4
, pp. 1060-1062
-
-
Ohmuraya, M.1
Yamamura, K.2
-
22
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 1997;389:610-614
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
23
-
-
34447257725
-
Hydroxychloroquine and risk of diabetes in patients with rheumatoid arthritis
-
Wasko MC, Hubert HB, Lingala VB, et al. Hydroxychloroquine and risk of diabetes in patients with rheumatoid arthritis. JAMA 298:187-193
-
JAMA
, vol.298
, pp. 187-193
-
-
Wasko, M.C.1
Hubert, H.B.2
Lingala, V.B.3
-
24
-
-
0033867178
-
Potential role of TNF-alpha in the pathogenesis of insulin resistance and type-2 diabetes
-
Moller DE. Potential role of TNF-alpha in the pathogenesis of insulin resistance and type-2 diabetes. Trends Endocrinol Metab 2000;11:212-217
-
(2000)
Trends Endocrinol Metab
, vol.11
, pp. 212-217
-
-
Moller, D.E.1
-
25
-
-
34147126829
-
The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk
-
Popa C, Netea MG, van Riel PL, et al. The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res 2007;48:751-762
-
(2007)
J Lipid Res
, vol.48
, pp. 751-762
-
-
Popa, C.1
Netea, M.G.2
Van Riel, P.L.3
-
26
-
-
0035180207
-
Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha mediated hepatocyte apoptosis and liver injury: Implications for therapeutic applications
-
Guicciardi ME, Miyoshi H, Bronk SF, Gores GJ. Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications. Am J Pathol 2001;159:2045-2054
-
(2001)
Am J Pathol
, vol.159
, pp. 2045-2054
-
-
Guicciardi, M.E.1
Miyoshi, H.2
Bronk, S.F.3
Gores, G.J.4
-
28
-
-
70449455395
-
Oral antidiabetic agents: Anti-atherosclerotic properties beyond glucose lowering?
-
Papanas N, Maltezos E. Oral antidiabetic agents: anti-atherosclerotic properties beyond glucose lowering? Curr Pharm Des 2009;15:3179-3192
-
(2009)
Curr Pharm des
, vol.15
, pp. 3179-3192
-
-
Papanas, N.1
Maltezos, E.2
-
29
-
-
29244469922
-
A practical guide to arylbiguanides: Synthesis and structural characterization
-
LeBel O, Maris T, Duval H, Wuest JD. A practical guide to arylbiguanides: synthesis and structural characterization Can J Chem 2005;83:615-625
-
(2005)
Can J Chem
, vol.83
, pp. 615-625
-
-
Lebel, O.1
Maris, T.2
Duval, H.3
Wuest, J.D.4
-
30
-
-
0142065613
-
Chemistry and structure--activity relationships of biguanides
-
Prugnard E, Noel M. Chemistry and structure--activity relationships of biguanides. Handb Exp Pharmacol 1995;119:263-282
-
(1995)
Handb Exp Pharmacol
, vol.119
, pp. 263-282
-
-
Prugnard, E.1
Noel, M.2
-
32
-
-
50649103962
-
Metal compounds for the treatment of parasitic diseases
-
Fricker SP, Mosi RM, Cameron BR, et al. Metal compounds for the treatment of parasitic diseases. J Inorg Biochem 2008;102:1839-1845
-
(2008)
J Inorg Biochem
, vol.102
, pp. 1839-1845
-
-
Fricker, S.P.1
Mosi, R.M.2
Cameron, B.R.3
-
34
-
-
0142039130
-
Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agents
-
Sweeney D, Raymer ML, Lockwood TD. Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agents. Biochem Pharmacol 2003;66:663-677
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 663-677
-
-
Sweeney, D.1
Raymer, M.L.2
Lockwood, T.D.3
-
35
-
-
7044230857
-
Cys--His proteases are among the wired proteins of the cell
-
Lockwood TD. Cys--His proteases are among the wired proteins of the cell. Arch Biochem Biophys 2004;432:12-24
-
(2004)
Arch Biochem Biophys
, vol.432
, pp. 12-24
-
-
Lockwood, T.D.1
-
36
-
-
70449698491
-
Acute metformin overdose: Examining serum pH, lactate level, and metformin concentrations in survivors versus nonsurvivors: A systematic review of the literature
-
Dell'Aglio DM, Perino LJ, Kazzi Z, et al. Acute metformin overdose: examining serum pH, lactate level, and metformin concentrations in survivors versus nonsurvivors: a systematic review of the literature. Ann Emerg Med 2009;54:818-823
-
(2009)
Ann Emerg Med
, vol.54
, pp. 818-823
-
-
Dell'Aglio, D.M.1
Perino, L.J.2
Kazzi, Z.3
-
37
-
-
0033007118
-
Redox-dependent and redox-independent subcomponents of protein degradation in perfused myocardium
-
Lockwood TD. Redox-dependent and redox-independent subcomponents of protein degradation in perfused myocardium. Am J Physiol 1999;276:E945-954
-
(1999)
Am J Physiol
, vol.276
-
-
Lockwood, T.D.1
-
38
-
-
0027266012
-
Four proteolytic processes of myocardium, one insensitive to thiol reactive agents and thiol protease inhibitor
-
Thorne DP, Lockwood TD. Four proteolytic processes of myocardium, one insensitive to thiol reactive agents and thiol protease inhibitor. Am J Physiol 1993;265:E10-19
-
(1993)
Am J Physiol
, vol.265
-
-
Thorne, D.P.1
Lockwood, T.D.2
-
39
-
-
0023901026
-
Determination of zinc in biological samples by atomic absorption spectrometry
-
Falchuk KH, Hilt KL, Vallee BL. Determination of zinc in biological samples by atomic absorption spectrometry. Methods Enzymol 1988;158:422-434
-
(1988)
Methods Enzymol
, vol.158
, pp. 422-434
-
-
Falchuk, K.H.1
Hilt, K.L.2
Vallee, B.L.3
-
40
-
-
44949264223
-
Copper, chromium, manganese, iron, nickel, and zinc levels in biological samples of diabetes mellitus patients
-
Kazi TG, Afridi HI, Kazi N, et al. Copper, chromium, manganese, iron, nickel, and zinc levels in biological samples of diabetes mellitus patients. Biol Trace Elem Res 2008;122:1-18
-
(2008)
Biol Trace Elem Res
, vol.122
, pp. 1-18
-
-
Kazi, T.G.1
Afridi, H.I.2
Kazi, N.3
-
41
-
-
0020536226
-
Tissue zinc status of genetically diabetic and streptozotocin-induced diabetic mice
-
Levine AS, McClain CJ, Handwerger BS, et al. Tissue zinc status of genetically diabetic and streptozotocin-induced diabetic mice. Am J Clin Nutr 1983;37:382-386
-
(1983)
Am J Clin Nutr
, vol.37
, pp. 382-386
-
-
Levine, A.S.1
McClain, C.J.2
Handwerger, B.S.3
-
42
-
-
59149099932
-
Albumin as a zinc carrier: Properties of its high-affinity zinc-binding site
-
Lu J, Stewart AJ, Sadler PJ, et al. Albumin as a zinc carrier: properties of its high-affinity zinc-binding site. Biochem Soc Trans 2008;36(Pt 6):1317-1321
-
(2008)
Biochem Soc Trans
, vol.36
, Issue.PART 6
, pp. 1317-1321
-
-
Lu, J.1
Stewart, A.J.2
Sadler, P.J.3
-
43
-
-
33746888208
-
Inhibitors of cathepsin B
-
Frlan R, Gobec S. Inhibitors of cathepsin B. Curr Med Chem 2006;13:2309-2327
-
(2006)
Curr Med Chem
, vol.13
, pp. 2309-2327
-
-
Frlan, R.1
Gobec, S.2
-
44
-
-
21344456357
-
Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: Inhibitory effect of metformin
-
Li L, Mamputu JC, Wiernsperger N, Renier G. Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: inhibitory effect of metformin. Diabetes 2005;54:2227-2234
-
(2005)
Diabetes
, vol.54
, pp. 2227-2234
-
-
Li, L.1
Mamputu, J.C.2
Wiernsperger, N.3
Renier, G.4
-
45
-
-
47949098831
-
Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages
-
Ha SD, Martins A, Khazaie K, et al. Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages. J Immunol 2008;181:690-697
-
(2008)
J Immunol
, vol.181
, pp. 690-697
-
-
Ha, S.D.1
Martins, A.2
Khazaie, K.3
-
46
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangk W, Lerch MM, Brandt-Nedelev B, et al. Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest 2000;106:773-781
-
(2000)
J Clin Invest
, vol.106
, pp. 773-781
-
-
Halangk, W.1
Lerch, M.M.2
Brandt-Nedelev, B.3
-
47
-
-
26444591985
-
Cathepsin L is essential for onset of autoimmune diabetes in NOD mice
-
Maehr R, Mintern JD, Herman AE, et al. Cathepsin L is essential for onset of autoimmune diabetes in NOD mice. Clin Invest 2005;115:2934-2943
-
(2005)
Clin Invest
, vol.115
, pp. 2934-2943
-
-
Maehr, R.1
Mintern, J.D.2
Herman, A.E.3
-
49
-
-
67349150186
-
Autophagy in human type 2 diabetes pancreatic beta cells
-
Masini M, Bugliani M, Lupi R, et al. Autophagy in human type 2 diabetes pancreatic beta cells. Diabetologia 2009;52:1083-1086
-
(2009)
Diabetologia
, vol.52
, pp. 1083-1086
-
-
Masini, M.1
Bugliani, M.2
Lupi, R.3
-
50
-
-
33751210335
-
Responsiveness of parasite Cys His proteases to iron redox
-
Lockwood TD. Responsiveness of parasite Cys His proteases to iron redox. Parasitol Res 2006;100:175-181
-
(2006)
Parasitol Res
, vol.100
, pp. 175-181
-
-
Lockwood, T.D.1
-
51
-
-
66149094205
-
Death receptor 5. internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines
-
Akazawa Y, Mott JL, Bronk SF, et al. Death receptor 5. internalization is required for lysosomal permeabilization by TRAIL in malignant liver cell lines. Gastroenterology 2009;136:2365-2376
-
(2009)
Gastroenterology
, vol.136
, pp. 2365-2376
-
-
Akazawa, Y.1
Mott, J.L.2
Bronk, S.F.3
-
52
-
-
22544442744
-
The cathepsin B death pathway contributes to TNF plus IFN-gamma-mediated human endothelial injury
-
Li JH, Pober JS. The cathepsin B death pathway contributes to TNF plus IFN-gamma-mediated human endothelial injury. J Immunol 2005;175:1858-1866
-
(2005)
J Immunol
, vol.175
, pp. 1858-1866
-
-
Li, J.H.1
Pober, J.S.2
-
53
-
-
70349263383
-
Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells
-
Li JH, D'Alessio A, Pober JS. Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells. Am J Pathol 2009;175:1124-1135
-
(2009)
Am J Pathol
, vol.175
, pp. 1124-1135
-
-
Li, J.H.1
D'Alessio, A.2
Pober, J.S.3
-
54
-
-
70349163894
-
Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe
-
Pratt MR, Sekedat MD, Chiang KP, Muir TW. Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe. Chem Biol 2009;16:1001-1012
-
(2009)
Chem Biol
, vol.16
, pp. 1001-1012
-
-
Pratt, M.R.1
Sekedat, M.D.2
Chiang, K.P.3
Muir, T.W.4
-
55
-
-
20444506408
-
Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism
-
Taha TA, Kitatani K, Bielawski J, et al. Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism. J Biol Chem 2005;280:17196-17202
-
(2005)
J Biol Chem
, vol.280
, pp. 17196-17202
-
-
Taha, T.A.1
Kitatani, K.2
Bielawski, J.3
-
56
-
-
65649145033
-
Role of cathepsin B-mediated apoptosis in fulminant hepatic failure in mice
-
Yan BZ, Wang W, Chen LY, et al. Role of cathepsin B-mediated apoptosis in fulminant hepatic failure in mice. World J Gastroenterol 2009;15:1231-1236
-
(2009)
World J Gastroenterol
, vol.15
, pp. 1231-1236
-
-
Yan, B.Z.1
Wang, W.2
Chen, L.Y.3
-
57
-
-
52049096824
-
Cystatins: Biochemical and structural properties, and medical relevance
-
Turk V, Stoka V, Turk D. Cystatins: biochemical and structural properties, and medical relevance. Front Biosci 2008;13:5406-5420
-
(2008)
Front Biosci
, vol.13
, pp. 5406-5420
-
-
Turk, V.1
Stoka, V.2
Turk, D.3
-
58
-
-
43349093939
-
Molecular background of EPM1-Unverricht-Lundborg disease
-
Joensuu T, Lehesjoki AE, Kopra O. Molecular background of EPM1-Unverricht-Lundborg disease. Epilepsia 2008;49:557-563
-
(2008)
Epilepsia
, vol.49
, pp. 557-563
-
-
Joensuu, T.1
Lehesjoki, A.E.2
Kopra, O.3
-
59
-
-
34247139737
-
Seizures, ataxia, and neuronal loss in cystatin B heterozygous mice
-
Kaasik A, Kuum M, Aonurm A, et al. Seizures, ataxia, and neuronal loss in cystatin B heterozygous mice. Epilepsia 2007;48:752-757
-
(2007)
Epilepsia
, vol.48
, pp. 752-757
-
-
Kaasik, A.1
Kuum, M.2
Aonurm, A.3
-
60
-
-
50349097188
-
Analysis of metal-binding proteins separated by non-denaturating gel electrophoresis using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS)
-
Becker JS, Mounicou S, Zoriy MV, et al. Analysis of metal-binding proteins separated by non-denaturating gel electrophoresis using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Talanta 2008;76:1183-1188
-
(2008)
Talanta
, vol.76
, pp. 1183-1188
-
-
Becker, J.S.1
Mounicou, S.2
Zoriy, M.V.3
-
61
-
-
58449134643
-
Autocatalytic processing of procathepsin B is triggered by proenzyme activity
-
Pungercar JR, Caglic D, Sajid M, et al. Autocatalytic processing of procathepsin B is triggered by proenzyme activity. FEBS J 2009;276:660-668
-
(2009)
FEBS J
, vol.276
, pp. 660-668
-
-
Pungercar, J.R.1
Caglic, D.2
Sajid, M.3
-
62
-
-
53049095258
-
Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B
-
Redzynia I, Ljunggren A, Abrahamson M, et al. Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J Biol Chem 2008;283:22815-22825
-
(2008)
J Biol Chem
, vol.283
, pp. 22815-22825
-
-
Redzynia, I.1
Ljunggren, A.2
Abrahamson, M.3
-
63
-
-
33747723380
-
Mammalian zinc transport, trafficking, and signals
-
Cousins RJ, Liuzzi JP, Lichten LA. Mammalian zinc transport, trafficking, and signals. J Biol Chem 2008;281:24085-24089
-
(2008)
J Biol Chem
, vol.281
, pp. 24085-24089
-
-
Cousins, R.J.1
Liuzzi, J.P.2
Lichten, L.A.3
-
65
-
-
49749124150
-
Intracellular zinc homeostasis and zinc signaling
-
Murakami M, Hirano T. Intracellular zinc homeostasis and zinc signaling. Cancer Sci 2008;99:1515-1522
-
(2008)
Cancer Sci
, vol.99
, pp. 1515-1522
-
-
Murakami, M.1
Hirano, T.2
-
67
-
-
54049156405
-
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel
-
Dong XP, Cheng X, Mills E, et al. The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel. Nature 2008;455:992-996
-
(2008)
Nature
, vol.455
, pp. 992-996
-
-
Dong, X.P.1
Cheng, X.2
Mills, E.3
-
68
-
-
0030763630
-
Chloroquine extends the lifetime of the activated insulin receptor complex in endosomes
-
Bevan AP, Krook A, Tikerpae J, et al. Chloroquine extends the lifetime of the activated insulin receptor complex in endosomes. J Biol Chem 1997;272:833-840
-
(1997)
J Biol Chem
, vol.272
, pp. 833-840
-
-
Bevan, A.P.1
Krook, A.2
Tikerpae, J.3
-
69
-
-
0021687736
-
In vivo chloroquine-induced inhibition of insulin degradation in a diabetic patient with severe insulin resistance
-
Blazar BR, Whitly CB, Kitabchi AE, et al. In vivo chloroquine-induced inhibition of insulin degradation in a diabetic patient with severe insulin resistance. Diabetes 1984;33:1133-1137
-
(1984)
Diabetes
, vol.33
, pp. 1133-1137
-
-
Blazar, B.R.1
Whitly, C.B.2
Kitabchi, A.E.3
-
70
-
-
24744459211
-
The pharmacology of the insulinomimetic effect of zinc complexes
-
Sakurai H, Adachi Y. The pharmacology of the insulinomimetic effect of zinc complexes. Biometals. 2005;8:319-323
-
(2005)
Biometals
, vol.8
, pp. 319-323
-
-
Sakurai, H.1
Adachi, Y.2
-
71
-
-
0032803011
-
Insulin-sparing effect of hydroxychloroquine in diabetic rats is concentration dependent
-
Emani J, Gerstein HC, Pasutto FM, Janmali F. Insulin-sparing effect of hydroxychloroquine in diabetic rats is concentration dependent. Can J Physiol Pharmacol 1999;77:118-123
-
(1999)
Can J Physiol Pharmacol
, vol.77
, pp. 118-123
-
-
Emani, J.1
Gerstein, H.C.2
Pasutto, F.M.3
Janmali, F.4
-
72
-
-
0036234949
-
In-vivo kinetics of 123 iodine-labelled insulin in skeletal muscle of patients with type-2 diabetes: Effects of metformin
-
Valensi P, Behar A, Cohen-Boulakia F, et al. In-vivo kinetics of 123 iodine-labelled insulin in skeletal muscle of patients with type-2 diabetes: effects of metformin. Diabet Metab 2002;28:95-103
-
(2002)
Diabet Metab
, vol.28
, pp. 95-103
-
-
Valensi, P.1
Behar, A.2
Cohen-Boulakia, F.3
-
75
-
-
4944243985
-
An expedient and facile one-step synthesis of a biguanide library by microwave irradiation coupled with simple product filtration. Inhibitors of dihydrofolate reductase
-
Mayer S, Daigle DM, Brown ED, et al. An expedient and facile one-step synthesis of a biguanide library by microwave irradiation coupled with simple product filtration. Inhibitors of dihydrofolate reductase. J Comb Chem 2004;6:776-782
-
(2004)
J Comb Chem
, vol.6
, pp. 776-782
-
-
Mayer, S.1
Daigle, D.M.2
Brown, E.D.3
|