-
2
-
-
0036229397
-
Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse
-
DOI 10.1046/j.1440-1746.2002.02662.x
-
Wang M, Gorrell MD, Abbott CA, Jaggi R, Marguet D, Dickinson RG. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol 2002; 17: 66-71. (Pubitemid 34304389)
-
(2002)
Journal of Gastroenterology and Hepatology
, vol.17
, Issue.1
, pp. 66-71
-
-
Wang, M.1
Gorrell, M.D.2
Abbott, C.A.3
Jaggi, R.4
Marguet, D.5
Dickinson, R.G.6
-
3
-
-
0028090694
-
Immunotoxicity of nitrobenzene in female B6C3F1 mice
-
Burns LA, Bradley SG, White KLJ et al. Immunotoxicity of nitrobenzene in female B6C3F1 mice. Drug Chem Toxicol 1994; 17: 271-315. (Pubitemid 24367329)
-
(1994)
Drug and Chemical Toxicology
, vol.17
, Issue.3
, pp. 271-315
-
-
Burns, L.A.1
Bradley, S.G.2
White Jr., K.L.3
McCay, J.A.4
Fuchs, B.A.5
Stern, M.6
Brown, R.D.7
Musgrove, D.L.8
Holsapple, M.P.9
Luster, M.I.10
Munson, A.E.11
-
5
-
-
0036639817
-
Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate
-
DOI 10.1016/S0006-2952(02)01015-8, PII S0006295202010158
-
Bode KA, Donner MG, Leier I, Keppler D. Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate. Biochem Pharmacol 2002; 64: 151-158. (Pubitemid 34775185)
-
(2002)
Biochemical Pharmacology
, vol.64
, Issue.1
, pp. 151-158
-
-
Bode, K.A.1
Donner, M.G.2
Leier, I.3
Keppler, D.4
-
6
-
-
0035036050
-
The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: A potential mechanism for hepatic adverse reactions
-
DOI 10.1067/mcp.2001.114667
-
Fattinger K, Funk C, Pantze M et al. The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions. Clin Pharmacol Ther 2001; 69: 223-231. (Pubitemid 32382504)
-
(2001)
Clinical Pharmacology and Therapeutics
, vol.69
, Issue.4
, pp. 223-231
-
-
Fattinger, K.1
Funk, C.2
Pantze, M.3
Weber, C.4
Reichen, J.5
Stieger, B.6
Meier, P.J.7
-
7
-
-
0035126136
-
Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: In vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat
-
Funk C, Ponelle C, Scheuermann G, Pantze M. Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat. Mol Pharmacol 2001; 59: 627-635. (Pubitemid 32179943)
-
(2001)
Molecular Pharmacology
, vol.59
, Issue.3
, pp. 627-635
-
-
Funk, C.1
Ponelle, C.2
Scheuermann, G.3
Pantze, M.4
-
8
-
-
34248562942
-
Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1) by bosentan: A mechanism for species differences in hepatotoxicity
-
Leslie EM, Watkins PB, Kim RB, Brouwer KL. Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1) by bosentan: a mechanism for species differences in hepatotoxicity. J Pharmacol Exp Ther 2007; 321: 1170-1178.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 1170-1178
-
-
Leslie, E.M.1
Watkins, P.B.2
Kim, R.B.3
Brouwer, K.L.4
-
9
-
-
0034930107
-
Thiazolidinediones and liver toxicity
-
Scheen AJ. Thiazolidinediones and liver toxicity. Diabetes Metab 2001; 27: 305-313.
-
(2001)
Diabetes Metab
, vol.27
, pp. 305-313
-
-
Scheen, A.J.1
-
10
-
-
33846532456
-
Effects of bosentan, an edothelin receptor antagonist, on bile salt export pump and multidrug resistance-associated protein 2
-
DOI 10.1002/bdd.527
-
Mano Y, Usui T, Kamimura H. Effects of bosentan, an endothelin receptor antagonist, on bile salt export pump and multidrug resistance-associated protein 2. Biopharm Drug Dispos 2007; 28: 13-18. (Pubitemid 46165160)
-
(2007)
Biopharmaceutics and Drug Disposition
, vol.28
, Issue.1
, pp. 13-18
-
-
Mano, Y.1
Usui, T.2
Kamimura, H.3
-
11
-
-
33747838057
-
+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs
-
DOI 10.1124/dmd.105.008748
-
Mita S, Suzuki H, Akita H et al. Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs. Drug Metab Dispos 2006; 34: 1575-1581. (Pubitemid 44285400)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.9
, pp. 1575-1581
-
-
Mita, S.1
Suzuki, H.2
Akita, H.3
Hayashi, H.4
Onuki, R.5
Hofmann, A.F.6
Sugiyama, Y.7
-
12
-
-
33644910207
-
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
-
Zelcer N, van deWetering K, deWaart R et al. Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. J Hepatol 2006; 44: 768-775.
-
(2006)
J Hepatol
, vol.44
, pp. 768-775
-
-
Zelcer, N.1
Van DeWetering, K.2
DeWaart, R.3
-
13
-
-
46449108452
-
Cellular accumulation of cholyl-glycylamido-fluorescein in sandwich-cultured rat hepatocytes: Kinetic characterization, transport mechanisms, and effect of human immunodeficiency virus protease inhibitors
-
DOI 10.1124/dmd.107.019398
-
Ye ZW, Augustijns P, Annaert P. Cellular accumulation of cholyl-glycylamido-fluorescein in sandwich-cultured rat hepatocytes: kinetic characterization, transport mechanisms, and effect of human immunodeficiency virus protease inhibitors. Drug Metab Dispos 2008; 36: 1315-1321. (Pubitemid 351929316)
-
(2008)
Drug Metabolism and Disposition
, vol.36
, Issue.7
, pp. 1315-1321
-
-
Ye, Z.-W.1
Augustijns, P.2
Annaert, P.3
-
14
-
-
77951062167
-
Species-specific interaction of HIV protease inhibitors with accumulation of cholyl-glycylamido-fluorescein (CGamF) in sandwich-cultured hepatocytes
-
in press
-
Ye ZW, Van Pelt J, Camus S, Snoeys J, Augustijns P, Annaert P. Species-specific interaction of HIV protease inhibitors with accumulation of cholyl-glycylamido-fluorescein (CGamF) in sandwich-cultured hepatocytes. J Pharm Sci 2009; (in press).
-
(2009)
J Pharm Sci
-
-
Ye, Z.W.1
Van Pelt, J.2
Camus, S.3
Snoeys, J.4
Augustijns, P.5
Annaert, P.6
-
15
-
-
48949097660
-
Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel
-
Hammer SM, Eron JJJ, Reiss P et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel. JAMA 2008; 300: 555-570.
-
(2008)
JAMA
, vol.300
, pp. 555-570
-
-
Hammer, S.M.1
Eron, J.J.J.2
Reiss, P.3
-
16
-
-
33748487397
-
Hepatotoxicity and antiretroviral therapy with protease inhibitors: A review
-
DOI 10.1016/j.dld.2006.01.020, PII S1590865806000211
-
Bruno R, Sacchi P, Maiocchi L, Patruno S, Filice G. Hepatotoxicity and antiretroviral therapy with protease inhibitors: A review. Dig Liver Dis 2006; 38: 363-373. (Pubitemid 44356213)
-
(2006)
Digestive and Liver Disease
, vol.38
, Issue.6
, pp. 363-373
-
-
Bruno, R.1
Sacchi, P.2
Maiocchi, L.3
Patruno, S.4
Filice, G.5
-
17
-
-
0030869269
-
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
-
DOI 10.1056/NEJM199709113371102
-
Gulick RM, Mellors JW, Havlir D et al. Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 1997; 337: 734-739. (Pubitemid 27417972)
-
(1997)
New England Journal of Medicine
, vol.337
, Issue.11
, pp. 734-739
-
-
Gulick, R.M.1
Mellors, J.W.2
Havlir, D.3
Eron, J.J.4
Gonzalez, C.5
McMahon, D.6
Richman, D.D.7
Valentine, F.T.8
Jonas, L.9
Meibohm, A.10
Emini, E.A.11
Chodakewitz, J.A.12
Deutsch, P.13
Holder, D.14
Schleif, W.A.15
Condra, J.H.16
-
18
-
-
33845495422
-
Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia
-
DOI 10.1097/QAD.0b013e328011d7c1, PII 0000203020070102000005
-
Rodriguez-Novoa S, Martin-Carbonero L, Barreiro P et al. Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia. AIDS 2007; 21: 41-46. (Pubitemid 44912535)
-
(2007)
AIDS
, vol.21
, Issue.1
, pp. 41-46
-
-
Rodriguez-Novoa, S.1
Martin-Carbonero, L.2
Barreiro, P.3
Gonzalez-Pardo, G.4
Jimenez-Nacher, I.5
Gonzalez-Lahoz, J.6
Soriano, V.7
-
19
-
-
1542327562
-
Drug-induced liver injury associated with antiretroviral therapy that includes HIV-1 protease inhibitors
-
Sulkowski MS. Drug-induced liver injury associated with antiretroviral therapy that includes HIV-1 protease inhibitors. Clin Infect Dis 2004; 38(Suppl 2): S90-S97.
-
(2004)
Clin Infect Dis
, vol.38
, Issue.SUPPL. 2
-
-
Sulkowski, M.S.1
-
20
-
-
33747627385
-
Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes
-
DOI 10.1124/jpet.106.102657
-
McRae MP, Lowe CM, Tian X et al. Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes. J Pharmacol Exp Ther 2006; 318: 1068-1075. (Pubitemid 44268312)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.318
, Issue.3
, pp. 1068-1075
-
-
McRae, M.P.1
Lowe, C.M.2
Tian, X.3
Bourdet, D.L.4
Ho, R.H.5
Leake, B.F.6
Kim, R.B.7
Brouwer, K.L.R.8
Kashuba, A.D.M.9
-
21
-
-
34250863207
-
Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor
-
DOI 10.1016/j.ijpharm.2007.02.036, PII S0378517307002037
-
Agarwal S, Pal D, Mitra AK. Both P-gp and MRP2 mediate transport of lopinavir, a protease inhibitor. Int J Pharm 2007; 339: 139-147. (Pubitemid 46977600)
-
(2007)
International Journal of Pharmaceutics
, vol.339
, Issue.1-2
, pp. 139-147
-
-
Agarwal, S.1
Pal, D.2
Mitra, A.K.3
-
22
-
-
0037159933
-
Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs
-
Huisman MT, Smit JW, Crommentuyn KM et al. Multidrug resistance protein 2 (MRP2) transports HIV protease inhibitors, and transport can be enhanced by other drugs. AIDS 2002; 16: 2295-2301.
-
(2002)
AIDS
, vol.16
, pp. 2295-2301
-
-
Huisman, M.T.1
Smit, J.W.2
Crommentuyn, K.M.3
-
23
-
-
0034822280
-
P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes
-
Annaert PP, Turncliff RZ, Booth CL, Thakker DR, Brouwer KL. P-glycoprotein-mediated in vitro biliary excretion in sandwich-cultured rat hepatocytes. Drug Metab Dispos 2001; 29: 1277-1283.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1277-1283
-
-
Annaert, P.P.1
Turncliff, R.Z.2
Booth, C.L.3
Thakker, D.R.4
Brouwer, K.L.5
-
24
-
-
0032815251
-
Biliary excretion in primary rat hepatocyte cultured in a collagen- Sandwich configuration
-
Liu X, LeCluyse EL, Brouwer KR et al. Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration. Am J Physiol 1999; 277: G12-G21. (Pubitemid 29352640)
-
(1999)
American Journal of Physiology - Gastrointestinal and Liver Physiology
, vol.277
, Issue.1
-
-
Liu, X.1
Lecluyse, E.L.2
Brouwer, K.R.3
Gan, L.-S.L.4
Lemasters, J.J.5
Stieger, B.6
Meier, P.J.7
Brouwer, K.L.R.8
-
25
-
-
0032589267
-
2+ modulation to evaluate biliary excretion in sandwich- Cultured rat hepatocytes
-
Liu X, LeCluyse EL, Brouwer KR, Lightfoot RM, Lee JI, Brouwer KL. Use of Ca2+ modulation to evaluate biliary excretion in sandwich-cultured rat hepatocytes. J Pharmacol Exp Ther 1999; 289: 1592-1599. (Pubitemid 29246695)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.289
, Issue.3
, pp. 1592-1599
-
-
Liu, X.1
Lecluyse, E.L.2
Brouwer, K.R.3
Lightfoot, R.M.4
Lee, J.I.5
Brouwer, K.L.R.6
-
26
-
-
33646490327
-
Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwichcultured rat hepatocytes
-
Turncliff RZ, Tian X, Brouwer KL. Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwichcultured rat hepatocytes. Biochem Pharmacol 2006; 71: 1520-1529.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1520-1529
-
-
Turncliff, R.Z.1
Tian, X.2
Brouwer, K.L.3
-
27
-
-
0028904919
-
Characterization of uptake and hydrolysis of fluorescein diacetate and carboxyfluorescein diacetate by intracellular esterases in Saccharomyces cerevisiae, which result in accumulation of fluorescent product
-
Breeuwer P, Drocourt JL, Bunschoten N, Zwietering MH, Rombouts FM, Abee T. Characterization of uptake and hydrolysis of fluorescein diacetate and carboxyfluorescein diacetate by intracellular esterases in Saccharomyces cerevisiae, which result in accumulation of fluorescent product. Appl Environ Microbiol 1995; 61: 1614-1619.
-
(1995)
Appl Environ Microbiol
, vol.61
, pp. 1614-1619
-
-
Breeuwer, P.1
Drocourt, J.L.2
Bunschoten, N.3
Zwietering, M.H.4
Rombouts, F.M.5
Abee, T.6
-
28
-
-
61649125402
-
Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human
-
Choi MK, Kim H, Han YH, Song IS, Shim CK. Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human. Xenobiotica 2009; 39: 171-181.
-
(2009)
Xenobiotica
, vol.39
, pp. 171-181
-
-
Choi, M.K.1
Kim, H.2
Han, Y.H.3
Song, I.S.4
Shim, C.K.5
-
29
-
-
46449094523
-
Inhibitory effects of terpenoids on multidrug resistance-associated protein 2-and breast cancer resistance protein-mediated transport
-
DOI 10.1124/dmd.107.019513
-
Yoshida N, Takada T, Yamamura Y, Adachi I, Suzuki H, Kawakami J. Inhibitory effects of terpenoids on multidrug resistance-associated protein 2- and breast cancer resistance protein-mediated transport. Drug Metab Dispos 2008; 36: 1206-1211. (Pubitemid 351929333)
-
(2008)
Drug Metabolism and Disposition
, vol.36
, Issue.7
, pp. 1206-1211
-
-
Yoshida, N.1
Takada, T.2
Yamamura, Y.3
Adachi, I.4
Suzuki, H.5
Kawakami, J.6
-
30
-
-
63849091178
-
Multidrug resistance protein 2-mediated estradiol- 17beta-D-glucuronide transport potentiation: In vitro-in vivo correlation and species specificity
-
Heredi-Szabo K, Glavinas H, Kis E et al. Multidrug resistance protein 2-mediated estradiol- 17beta-D-glucuronide transport potentiation: in vitro-in vivo correlation and species specificity. Drug Metab Dispos 2009; 37: 794-801.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 794-801
-
-
Heredi-Szabo, K.1
Glavinas, H.2
Kis, E.3
-
32
-
-
0034000292
-
Regeneration and maintenance of bile canalicular networks in collagen-sandwiched hepatocytes
-
LeCluyse EL, Fix JA, Audus KL, Hochman JH. Regeneration and maintenance of bile canalicular networks in collagen-sandwiched hepatocytes. Toxicol In Vitro 2000; 14: 117-132.
-
(2000)
Toxicol in Vitro
, vol.14
, pp. 117-132
-
-
LeCluyse, E.L.1
Fix, J.A.2
Audus, K.L.3
Hochman, J.H.4
-
33
-
-
0031691798
-
Partial maintenance of taurocholate uptake by adult rat hepatocytes cultured in a collagen sandwich configuration
-
DOI 10.1023/A:1011994831139
-
Liu X, Brouwer KL, Gan LS et al. Partial maintenance of taurocholate uptake by adult rat hepatocytes cultured in a collagen sandwich configuration. Pharm Res 1998; 15: 1533-1539. (Pubitemid 28465738)
-
(1998)
Pharmaceutical Research
, vol.15
, Issue.10
, pp. 1533-1539
-
-
Liu, X.1
Brouwer, K.L.R.2
Gan, L.-S.L.3
Brouwer, K.R.4
Stieger, B.5
Meier, P.J.6
Audus, K.L.7
Lecluyse, E.L.8
-
34
-
-
10844279077
-
Effects of grapefruit juice and orange juice components on P-glycoprotein- And MRP2-mediated drug efflux
-
DOI 10.1038/sj.bjp.0706008
-
Honda Y, Ushigome F, Koyabu N et al. Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux. Br J Pharmacol 2004; 143: 856-864. (Pubitemid 39664844)
-
(2004)
British Journal of Pharmacology
, vol.143
, Issue.7
, pp. 856-864
-
-
Honda, Y.1
Ushigome, F.2
Koyabu, N.3
Morimoto, S.4
Shoyama, Y.5
Uchiumi, T.6
Kuwano, M.7
Ohtani, H.8
Sawada, Y.9
-
35
-
-
50249154146
-
Interaction of dipeptide prodrugs of saquinavir with multidrug resistance protein-2 (MRP-2): Evasion of MRP-2 mediated efflux
-
Jain R, Agarwal S, Mandava NK, Sheng Y, Mitra AK. Interaction of dipeptide prodrugs of saquinavir with multidrug resistance protein-2 (MRP-2): evasion of MRP-2 mediated efflux. Int J Pharm 2008; 362: 44-51.
-
(2008)
Int J Pharm
, vol.362
, pp. 44-51
-
-
Jain, R.1
Agarwal, S.2
Mandava, N.K.3
Sheng, Y.4
Mitra, A.K.5
-
36
-
-
2442638219
-
Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of saquinavir in Hep G2 cells
-
Su Y, Zhang X, Sinko PJ. Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of saquinavir in Hep G2 cells. Mol Pharm 2004; 1: 49-56.
-
(2004)
Mol Pharm
, vol.1
, pp. 49-56
-
-
Su, Y.1
Zhang, X.2
Sinko, P.J.3
-
37
-
-
0036839699
-
Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2)
-
DOI 10.1128/AAC.46.11.3456-3462.2002
-
Williams GC, Liu A, Knipp G, Sinko PJ. Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2). Antimicrob Agents Chemother 2002; 46: 3456-3462. (Pubitemid 35192911)
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, Issue.11
, pp. 3456-3462
-
-
Williams, G.C.1
Liu, A.2
Knipp, G.3
Sinko, P.J.4
-
38
-
-
42449083749
-
Differential roles of P-glycoprotein, multidrug resistance-associated protein 2, and CYP3A on saquinavir oral absorption in Sprague-Dawley rats
-
DOI 10.1124/dmd.107.017483
-
Usansky HH, Hu P, Sinko PJ. Differential roles of P-glycoprotein, multidrug resistance-associated protein 2, and CYP3A on saquinavir oral absorption in Sprague-Dawley rats. Drug Metab Dispos 2008; 36: 863-869. (Pubitemid 351574883)
-
(2008)
Drug Metabolism and Disposition
, vol.36
, Issue.5
, pp. 863-869
-
-
Usansky, H.H.1
Hu, P.2
Sinko, P.J.3
-
39
-
-
14344264538
-
P-glycoprotein and mutlidrug resistance-associated proteins limit the brain uptake of saquinavir in mice
-
DOI 10.1124/jpet.104.076216
-
Park S, Sinko PJ. P-glycoprotein and multidrug resistance-associated proteins limit the brain uptake of saquinavir in mice. J Pharmacol Exp Ther 2005; 312: 1249-1256. (Pubitemid 40293787)
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.312
, Issue.3
, pp. 1249-1256
-
-
Park, S.1
Sinko, P.J.2
-
40
-
-
56749117743
-
Lopinavir/ritonavir in the treatment of HIV-1 infection: A review
-
Chandwani A, Shuter J. Lopinavir/ritonavir in the treatment of HIV-1 infection: a review. Ther Clin Risk Manag 2008; 4: 1023-1033.
-
(2008)
Ther Clin Risk Manag
, vol.4
, pp. 1023-1033
-
-
Chandwani, A.1
Shuter, J.2
-
41
-
-
26944450008
-
Nelfinavir: A review of its use in the management of HIV infection
-
DOI 10.2165/00003495-200565150-00015
-
Perry CM, Frampton JE, McCormack PL, Siddiqui MA, Cvetkovic RS. Nelfinavir: a review of its use in the management of HIV infection. Drugs 2005; 65: 2209-2244. (Pubitemid 41478798)
-
(2005)
Drugs
, vol.65
, Issue.15
, pp. 2209-2244
-
-
Perry, C.M.1
Frampton, J.E.2
McCormack, P.L.3
Siddiqui, M.A.A.4
Cvetkovic, R.S.5
-
42
-
-
0032806043
-
Species differences in the transport activity for organic anions across the bile canalicular membrane
-
Ishizuka H, Konno K, Shiina T et al. Species differences in the transport activity for organic anions across the bile canalicular membrane. J Pharmacol Exp Ther 1999; 290: 1324-1330. (Pubitemid 29400276)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.290
, Issue.3
, pp. 1324-1330
-
-
Ishizuka, H.1
Konno, K.2
Shiina, T.3
Naganuma, H.4
Nishimura, K.5
Ito, K.6
Suzuki, H.7
Sugiyama, Y.8
-
43
-
-
33646230798
-
Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane
-
Shilling AD, Azam F, Kao J, Leung L. Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane. J Pharmacol Toxicol Methods 2006; 53: 186-197.
-
(2006)
J Pharmacol Toxicol Methods
, vol.53
, pp. 186-197
-
-
Shilling, A.D.1
Azam, F.2
Kao, J.3
Leung, L.4
-
44
-
-
13444250882
-
Functional analysis of dog multidrug resistance-associated protein 2 (Mrp2) in comparison with rat Mrp2
-
DOI 10.1124/dmd.104.002196
-
Ninomiya M, Ito K, Horie T. Functional analysis of dog multidrug resistance-associated protein 2 (Mrp2) in comparison with rat Mrp2. Drug Metab Dispos 2005; 33: 225-232. (Pubitemid 40216590)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.2
, pp. 225-232
-
-
Ninomiya, M.1
Ito, K.2
Horie, T.3
-
45
-
-
58149465922
-
Absolute difference of hepatobiliary transporter multidrug resistance-associated protein (MRP2/Mrp2) in liver tissues and isolated hepatocytes from rat, dog, monkey, and human
-
Li N, Zhang Y, Hua F, Lai Y. Absolute difference of hepatobiliary transporter multidrug resistance-associated protein (MRP2/Mrp2) in liver tissues and isolated hepatocytes from rat, dog, monkey, and human. Drug Metab Dispos 2009; 37: 66-73.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 66-73
-
-
Li, N.1
Zhang, Y.2
Hua, F.3
Lai, Y.4
-
46
-
-
0037963557
-
Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions
-
DOI 10.1074/jbc.M303515200
-
Bodo A, Bakos E, Szeri F, Varadi A, Sarkadi B. Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions. J Biol Chem 2003; 278: 23529-23537. (Pubitemid 36830172)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.26
, pp. 23529-23537
-
-
Bodso, A.1
Bakos, E.2
Szeri, F.3
Varadi, A.4
Sarkadi, B.5
-
47
-
-
0033936291
-
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export
-
Evers R, de Haas M, Sparidans R et al. Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export. Br J Cancer 2000; 83: 375-383. (Pubitemid 30453579)
-
(2000)
British Journal of Cancer
, vol.83
, Issue.3
, pp. 375-383
-
-
Evers, R.1
De Haas, M.2
Sparidans, R.3
Beijnen, J.4
Wielinga, P.R.5
Lankelma, J.6
Borst, P.7
-
48
-
-
0037666795
-
Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2)
-
DOI 10.1074/jbc.M303504200
-
Zelcer N, Huisman MT, Reid G et al. Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2). J Biol Chem 2003; 278: 23538-23544. (Pubitemid 36830173)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.26
, pp. 23538-23544
-
-
Zelcer, N.1
Huisman, M.T.2
Reid, G.3
Wielinga, P.4
Breedveld, P.5
Kuil, A.6
Knipscheer, P.7
Schellens, J.H.M.8
Schinkel, A.H.9
Borst, P.10
-
50
-
-
41549156918
-
Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2)
-
DOI 10.1124/dmd.107.019620
-
Zimmermann C, van de Wetering K, van de Steeg E, Wagenaar E, Vens C, Schinkel AH. Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2). Drug Metab Dispos 2008; 36: 631-640. (Pubitemid 351468367)
-
(2008)
Drug Metabolism and Disposition
, vol.36
, Issue.4
, pp. 631-640
-
-
Zimmermann, C.1
Van De Wetering, K.2
Van De Steeg, E.3
Wagenaar, E.4
Vens, C.5
Schinkel, A.H.6
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