Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: In vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat

Molecular Pharmacology

Volumn 59, Issue 3, 2001, Pages 627-635

  Funk, Christoph ^a   Ponelle, Christiane ^a   Scheuermann, Gerd ^a   Pantze, Michael ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; BILE SALT; DRUG METABOLITE; TAUROCHOLIC ACID; TROGLITAZONE; TROGLITAZONE SULFATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CHOLESTASIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INTRAHEPATIC BILE DUCT; LIVER TOXICITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0035126136     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.3.627     Document Type: Article

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