Peroxisome proliferator-activated receptor δ is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart

Circulation Research

Volumn 106, Issue 5, 2010, Pages 911-919

  Wang, Peiyong ^a   Liu, Jian ^a   Li, Yuquan ^a   Wu, Sijie ^a   Luo, Jinwen ^a   Yang, Huan ^a   Subbiah, Ramasamy ^a   Chatham, John ^b   Zhelyabovska, Olga ^a   Yang, Qinglin ^a  

^a Department of Nutrition Sciences ^*  (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Antioxidants; Cardiac function; Mitochondrial biogenesis; PPAR

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; DNA; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PROTEIN; ANTIOXIDANT; GLUCOSE; MESSENGER RNA; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CELL PROTECTION; CONTROLLED STUDY; COPY NUMBER VARIATION; ENZYME METABOLISM; GLUCOSE OXIDATION; HEART; HEART MUSCLE CELL; HEART PERFORMANCE; HEART VENTRICLE HYPERTROPHY; LIPID METABOLISM; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR DOWN REGULATION; TRANSCRIPTION REGULATION; AGING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CARDIOMEGALY; CELL CULTURE; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART MITOCHONDRION; HOMEOSTASIS; METABOLISM; MOUSE; MOUSE MUTANT; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOLOGY;

AGING; ANIMALS; ANTIOXIDANTS; CARDIOMEGALY; CELLS, CULTURED; DNA, MITOCHONDRIAL; ENERGY METABOLISM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; HOMEOSTASIS; LIPID METABOLISM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; OXIDATION-REDUCTION; OXIDATIVE STRESS; PALMITIC ACID; PPAR DELTA; RNA, MESSENGER; SUPEROXIDE DISMUTASE; TRANSCRIPTION, GENETIC; VENTRICULAR DYSFUNCTION, LEFT;

EID: 77950874188     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.206185     Document Type: Article

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