-
1
-
-
0034534704
-
Baicalin, the predominant flavones glucuronide of Scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form
-
Akao T, Kawabata K, Yanagisawa E, Ishihara K, Mizuhara Y, Wakui Y, Sakashita Y, Kobashi K. (2000). Baicalin, the predominant flavones glucuronide of Scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form. J Pharmacy Pharmacol 52:1563-1568
-
(2000)
J Pharmacy Pharmacol
, vol.52
, pp. 1563-1568
-
-
Akao, T.1
Kawabata, K.2
Yanagisawa, E.3
Ishihara, K.4
Mizuhara, Y.5
Wakui, Y.6
Sakashita, Y.7
Kobashi, K.8
-
2
-
-
21644436299
-
Enteric excretion of baicalein, a flavones of Scutellariae radix, via glucuronidation in rat: Involvement of multidrug resistanceassociated protein 2
-
Akao T, Sakashita Y, Hanada M, Goto H, Shimada Y, Teresawa K. (2004). Enteric excretion of baicalein, a flavones of Scutellariae radix, via glucuronidation in rat: involvement of multidrug resistanceassociated protein 2. Pharmaceut Res 21:2120-2126
-
(2004)
Pharmaceut Res
, vol.21
, pp. 2120-2126
-
-
Akao, T.1
Sakashita, Y.2
Hanada, M.3
Goto, H.4
Shimada, Y.5
Teresawa, K.6
-
3
-
-
73449105433
-
Hepatic contribution to a marked increase in the plasma concentration of baicalin after oral administration of its aglycone, baicalein, in multidrug resistance-associated protein 2-deficient rat
-
Akao T, Sato K, Hanada M. (2009). Hepatic contribution to a marked increase in the plasma concentration of baicalin after oral administration of its aglycone, baicalein, in multidrug resistance-associated protein 2-deficient rat. Biol Pharmaceut Bull 32:2079-2082
-
(2009)
Biol Pharmaceut Bull
, vol.32
, pp. 2079-2082
-
-
Akao, T.1
Sato, K.2
Hanada, M.3
-
4
-
-
70349768928
-
Artemisinin-a possible CYP2B6 probe substrate?
-
Asimus S, Ashton M. (2009). Artemisinin-a possible CYP2B6 probe substrate? Biopharmaceut Drug Disposit 30:265-275
-
(2009)
Biopharmaceut Drug Disposit
, vol.30
, pp. 265-275
-
-
Asimus, S.1
Ashton, M.2
-
5
-
-
67649960169
-
Influence of the cytochrome P450 2B6 genotype on population pharmacokinetics of efavirenz in human immunodeficiency virus patients
-
Cabrera SE, Santos D, Valverde MP, Domínguez-Gil A, Gonzalez F, Luna G, Garcia MJ. (2009). Influence of the cytochrome P450 2B6 genotype on population pharmacokinetics of efavirenz in human immunodeficiency virus patients. Antimicrob Agent Chemother 53:2791-2798
-
(2009)
Antimicrob Agent Chemother
, vol.53
, pp. 2791-2798
-
-
Cabrera, S.E.1
Santos, D.2
Valverde, M.P.3
Domínguez-Gil, A.4
Gonzalez, F.5
Luna, G.6
Garcia, M.J.7
-
6
-
-
68249092793
-
The role of pH in the glucuronidation of raloxifene, mycophenolic acid and ezetimibe
-
Chang JH, Yoo P, Lee T, Klopf W, Takao D. (2009). The role of pH in the glucuronidation of raloxifene, mycophenolic acid and ezetimibe. Mol Pharmacol 6:1216-1227
-
(2009)
Mol Pharmacol
, vol.6
, pp. 1216-1227
-
-
Chang, J.H.1
Yoo, P.2
Lee, T.3
Klopf, W.4
Takao, D.5
-
8
-
-
62549121605
-
Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation
-
Fan L, Wang JC, Jiang F, Tan ZR, Chen Y, Li Q, Zhang W, Wang G, Lei HP, Hu DL, Wang D, Zhou HH. (2009). Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation. Eur J Clin Pharmacol 65:403-409
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 403-409
-
-
Fan, L.1
Wang, J.C.2
Jiang, F.3
Tan, Z.R.4
Chen, Y.5
Li, Q.6
Zhang, W.7
Wang, G.8
Lei, H.P.9
Hu, D.L.10
Wang, D.11
Zhou, H.H.12
-
9
-
-
39449122141
-
The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1
-
Fan L, Zhang W, Guo D, Tan ZR, Xu P, Li Q, Liu YZ, Zhang L, He TY, Hu DL, Wang D, Zhou HH. (2008). The effect of herbal medicine baicalin on pharmacokinetics of rosuvastatin, substrate of organic anion-transporting polypeptide 1B1. Clin Pharmacol Therapeut 83:471-476
-
(2008)
Clin Pharmacol Therapeut
, vol.83
, pp. 471-476
-
-
Fan, L.1
Zhang, W.2
Guo, D.3
Tan, Z.R.4
Xu, P.5
Li, Q.6
Liu, Y.Z.7
Zhang, L.8
He, T.Y.9
Hu, D.L.10
Wang, D.11
Zhou, H.H.12
-
10
-
-
33845207780
-
Gradient high-performance liquid chromatography for the simultaneous determination of chlorogenic acid and baicalin in plasma and its application in the study of pharmacokinetics in rats
-
Gao R, Zheng Q, Gong T, Fu Y, Deng L, Zhang ZR. (2007). Gradient high-performance liquid chromatography for the simultaneous determination of chlorogenic acid and baicalin in plasma and its application in the study of pharmacokinetics in rats. J Pharmaceut Biomed Anal 43:335-340
-
(2007)
J Pharmaceut Biomed Anal
, vol.43
, pp. 335-340
-
-
Gao, R.1
Zheng, Q.2
Gong, T.3
Fu, Y.4
Deng, L.5
Zhang, Z.R.6
-
11
-
-
0032750323
-
Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi
-
Gao Z, Huang K, Yang X, Xu H. (1999). Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Biochimica Biophysics Acta 1472:643-650
-
(1999)
Biochimica Biophysics Acta
, vol.1472
, pp. 643-650
-
-
Gao, Z.1
Huang, K.2
Yang, X.3
Xu, H.4
-
12
-
-
1342344756
-
Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (ZETIA)
-
DOI 10.1124/dmd.32.3.314
-
Ghosal A, Hapangama N, Yuan Y, Achanfuo-Yeboah J, Iannucci R, Chowdhury S, Alton K, Patrick JE, Zbaida S. (2004). Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). Drug Metab Disposit 32:314-320 (Pubitemid 38263889)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.3
, pp. 314-320
-
-
Ghosal, A.1
Hapangama, N.2
Yuan, Y.3
Achanfuo-Yeboah, J.4
Iannucci, R.5
Chowdhury, S.6
Alton, K.7
Patrick, J.E.8
Zbaida, S.9
-
13
-
-
70449370069
-
Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet
-
Guo HX, Liu DH, Ma Y, Liu JF, Wang Y, Du ZY, Wang X, Shen JK, Peng HL. (2009). Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet. Acta Pharmacologica Sinica 30:1505-1512.
-
(2009)
Acta Pharmacologica Sinica
, vol.30
, pp. 1505-1512
-
-
Guo, H.X.1
Liu, D.H.2
Ma, Y.3
Liu, J.F.4
Wang, Y.5
Du, Z.Y.6
Wang, X.7
Shen, J.K.8
Peng, H.L.9
-
14
-
-
53249087817
-
Determination of baicalin in rat cerebrospinal fluid and blood using microdialysis coupled with ultra-performance liquid chromatography-tandem mass spectrometry
-
Huang H, Zhang Y, Yang R, Tang X. (2008). Determination of baicalin in rat cerebrospinal fluid and blood using microdialysis coupled with ultra-performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Tech Biomed Life Sci 874:77-83.
-
(2008)
J Chromatogr B Analyt Tech Biomed Life Sci
, vol.874
, pp. 77-83
-
-
Huang, H.1
Zhang, Y.2
Yang, R.3
Tang, X.4
-
15
-
-
0034025809
-
Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines
-
Ikemoto S, Sugimura K, Yoshida N, Yasumoto R, Wada S, Yamamoto K, Kishimoto T. (2000). Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. Urology 55:951-955
-
(2000)
Urology
, vol.55
, pp. 951-955
-
-
Ikemoto, S.1
Sugimura, K.2
Yoshida, N.3
Yasumoto, R.4
Wada, S.5
Yamamoto, K.6
Kishimoto, T.7
-
16
-
-
17644374513
-
Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2
-
Itoh T, itagaki S, Sumi Y, Hirano T, Takemoto I, Iseki K. (2005). Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2. Cancer Chemother Pharmacol 55:420-424
-
(2005)
Cancer Chemother Pharmacol
, vol.55
, pp. 420-424
-
-
Itoh, T.1
Itagaki, S.2
Sumi, Y.3
Hirano, T.4
Takemoto, I.5
Iseki, K.6
-
17
-
-
0345167010
-
Hepatoprotective effect of baicalin, a major flavones from Scutellaria radix, on acetaminophen-induced liver injury in mice
-
Jang SI, Kim HJ, Hwang KM, Jekal SJ, Pae HO, Choi BM, Yun YG, Kwon TO, Chung HT, Kim YC. (2003). Hepatoprotective effect of baicalin, a major flavones from Scutellaria radix, on acetaminophen-induced liver injury in mice. Immunopharmacol Immunotoxicol 25:585-594
-
(2003)
Immunopharmacol Immunotoxicol
, vol.25
, pp. 585-594
-
-
Jang, S.I.1
Kim, H.J.2
Hwang, K.M.3
Jekal, S.J.4
Pae, H.O.5
Choi, B.M.6
Yun, Y.G.7
Kwon, T.O.8
Chung, H.T.9
Kim, Y.C.10
-
18
-
-
18844431909
-
Species- and disposition model-dependent metabolism of raloxifene in gut and liver: Role of UGT1A10
-
Jeong EJ, Liu Y, Lin H, Hu M. (2005). Species- and disposition model-dependent metabolism of raloxifene in gut and liver: role of UGT1A10. Drug Metab Disposit 33:785-794
-
(2005)
Drug Metab Disposit
, vol.33
, pp. 785-794
-
-
Jeong, E.J.1
Liu, Y.2
Lin, H.3
Hu, M.4
-
19
-
-
33751330657
-
Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma
-
Kim YH, Jeong DW, Paek IB, Ji HY, Kim YC, Sohn DH, Lee HS. (2006). Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. J Chromatogr B Analyt Tech Biomed Life Sci 844:261-267
-
(2006)
J Chromatogr B Analyt Tech Biomed Life Sci
, vol.844
, pp. 261-267
-
-
Kim, Y.H.1
Jeong, D.W.2
Paek, I.B.3
Ji, H.Y.4
Kim, Y.C.5
Sohn, D.H.6
Lee, H.S.7
-
20
-
-
0032005662
-
Baicalin, an inhibitor of HIV-1 production in vitro
-
Kitamura K, Honda M, Yoshizaki H, Yamamoto S, Nakane H, Fukushima M, Ono K, Tokunga T. (1998). Baicalin, an inhibitor of HIV-1 production in vitro. Antiviral Res 37:131-140
-
(1998)
Antiviral Res
, vol.37
, pp. 131-140
-
-
Kitamura, K.1
Honda, M.2
Yoshizaki, H.3
Yamamoto, S.4
Nakane, H.5
Fukushima, M.6
Ono, K.7
Tokunga, T.8
-
21
-
-
32644486652
-
HPLC with electrochemical detection to examine the pharmacokinetics of baicalin and baicalein in rat plasma after oral administration of a Kampo medicine
-
Kotani A, Kojima S, Hakamata H, Kusu F. (2006). HPLC with electrochemical detection to examine the pharmacokinetics of baicalin and baicalein in rat plasma after oral administration of a Kampo medicine. Analyt Biochem 350:99-104.
-
(2006)
Analyt Biochem
, vol.350
, pp. 99-104
-
-
Kotani, A.1
Kojima, S.2
Hakamata, H.3
Kusu, F.4
-
22
-
-
0038382966
-
Urinary pharmacokinetics of baicalein, wogonin, and their glycosides after oral administration of Scutellariae radix in humans
-
Lai MY, Hsiu SL, Chen CC, Hou YC, Chao PD. (2003). Urinary pharmacokinetics of baicalein, wogonin, and their glycosides after oral administration of Scutellariae radix in humans. Biol Pharmaceut Bull 26:79-83.
-
(2003)
Biol Pharmaceut Bull
, vol.26
, pp. 79-83
-
-
Lai, M.Y.1
Hsiu, S.L.2
Chen, C.C.3
Hou, Y.C.4
Chao, P.D.5
-
23
-
-
1542344492
-
Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis
-
Lai MY, Hsiu SL, Hou YC, Tsai SY, Chao PD. (2004). Significant decrease of cyclosporine bioavailability in rats caused by a decoction of the roots of Scutellaria baicalensis. Planta Medica 70:132-137
-
(2004)
Planta Medica
, vol.70
, pp. 132-137
-
-
Lai, M.Y.1
Hsiu, S.L.2
Hou, Y.C.3
Tsai, S.Y.4
Chao, P.D.5
-
24
-
-
0344642935
-
Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats
-
Lai MY, Hsiu SL, Tsai SY, Hou YC, Chao PD. (2003). Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats. J Pharmacy Pharmacol 55:205-209
-
(2003)
J Pharmacy Pharmacol
, vol.55
, pp. 205-209
-
-
Lai, M.Y.1
Hsiu, S.L.2
Tsai, S.Y.3
Hou, Y.C.4
Chao, P.D.5
-
25
-
-
33846571368
-
Effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers
-
Lau YY, Huang Y, Frassetto L, Benet LZ. (2007). Effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers. Clin Pharmacol Therapeut 81:194-204.
-
(2007)
Clin Pharmacol Therapeut
, vol.81
, pp. 194-204
-
-
Lau, Y.Y.1
Huang, Y.2
Frassetto, L.3
Benet, L.Z.4
-
26
-
-
70350437658
-
Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenisis pathway
-
Lee H, Kang R, Hahn Y, Yang Y, Kim SS, Cho SH, Chung SI, Yoon Y. (2009). Antiobesity effect of baicalin involves the modulations of proadipogenic and antiadipogenic regulators of the adipogenisis pathway. Phytother Res 23:1615-1623
-
(2009)
Phytother Res
, vol.23
, pp. 1615-1623
-
-
Lee, H.1
Kang, R.2
Hahn, Y.3
Yang, Y.4
Kim, S.S.5
Cho, S.H.6
Chung, S.I.7
Yoon, Y.8
-
27
-
-
49949100063
-
Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers
-
Levesque E, Benoit-Biancamano MO, Delage R, Couture F, Guillemette C. (2008). Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers. Pharmacogenomics 9:869-879
-
(2008)
Pharmacogenomics
, vol.9
, pp. 869-879
-
-
Levesque, E.1
Benoit-Biancamano, M.O.2
Delage, R.3
Couture, F.4
Guillemette, C.5
-
28
-
-
74549193938
-
Increased oral AUC of baicalin in streptozotocin-induced diabetic rats due to the increased activity of intestinal beta-glucuronidase
-
Liu L, Deng YX, Liang Y, Pang XY, Liu XD, Liu YW, Yang JS, Xie L, Wang GJ. (2010). Increased oral AUC of baicalin in streptozotocin-induced diabetic rats due to the increased activity of intestinal beta-glucuronidase. Planta Medica 76:70-75
-
(2010)
Planta Medica
, vol.76
, pp. 70-75
-
-
Liu, L.1
Deng, Y.X.2
Liang, Y.3
Pang, X.Y.4
Liu, X.D.5
Liu, Y.W.6
Yang, J.S.7
Xie, L.8
Wang, G.J.9
-
29
-
-
70449115222
-
Effects of labrasol on the corneal drug delivery of baicalin
-
Liu Z, Zhang X, Li J, Liu R, Shu L, Jin J. (2009). Effects of labrasol on the corneal drug delivery of baicalin. Drug Del 16:399-404.
-
(2009)
Drug Del
, vol.16
, pp. 399-404
-
-
Liu, Z.1
Zhang, X.2
Li, J.3
Liu, R.4
Shu, L.5
Jin, J.6
-
30
-
-
33847790184
-
Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats
-
Lu T, Song J, Huang F, Deng Y, Xie L, Wang G, Liu X. (2007). Comparative pharmacokinetics of baicalin after oral administration of pure baicalin, Radix scutellariae extract and Huang-Lian-Jie-Du-Tang to rats. J Ethnopharmacol 110:412-418
-
(2007)
J Ethnopharmacol
, vol.110
, pp. 412-418
-
-
Lu, T.1
Song, J.2
Huang, F.3
Deng, Y.4
Xie, L.5
Wang, G.6
Liu, X.7
-
31
-
-
34547178337
-
Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1: OATP2B1:and OATP1B3
-
Noe J, Portmann R, Brun ME, Funk C. (2007). Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1:OATP2B1:and OATP1B3. Drug Metab Disposit 35:1308-1314
-
(2007)
Drug Metab Disposit
, vol.35
, pp. 1308-1314
-
-
Noe, J.1
Portmann, R.2
Brun, M.E.3
Funk, C.4
-
32
-
-
53049109106
-
Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1
-
Oswald S, Konig J, Lutjohann D, Giessmann T, Kroemer HK, Rimmbach C, Rosskopf D, Fromm MF, Siegmund W. (2008). Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1. Pharmacogenet Gen 18:559-568
-
(2008)
Pharmacogenet Gen
, vol.18
, pp. 559-568
-
-
Oswald, S.1
Konig, J.2
Lutjohann, D.3
Giessmann, T.4
Kroemer, H.K.5
Rimmbach, C.6
Rosskopf, D.7
Fromm, M.F.8
Siegmund, W.9
-
33
-
-
0141619406
-
HPLC analyses and pharmacokinetic studies of baicalin and oxymatrine in rabbits
-
Qiu F, He ZG, Li HZ. (2003). HPLC analyses and pharmacokinetic studies of baicalin and oxymatrine in rabbits. Pharmazie 58:616-619
-
(2003)
Pharmazie
, vol.58
, pp. 616-619
-
-
Qiu, F.1
He, Z.G.2
Li, H.Z.3
-
34
-
-
33748155243
-
Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatographytandem mass spectrometry
-
Ran X, Liang Q, Luo G, Liu Q, Pan Y, Wang B, Pang C. (2006). Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatographytandem mass spectrometry. J Chromatogr B Analyt Tech Biomed Life Sci 842:22-27
-
(2006)
J Chromatogr B Analyt Tech Biomed Life Sci
, vol.842
, pp. 22-27
-
-
Ran, X.1
Liang, Q.2
Luo, G.3
Liu, Q.4
Pan, Y.5
Wang, B.6
Pang, C.7
-
35
-
-
49649084692
-
A study of the pharmacokinetic interaction of istradefylline, a novel therapeutic for Parkinson's disease, and atorvastatin
-
Rao N, Dvorchik B, Sussman N, Wang H, Yamamoto K, Mori A, Uchimura T, Chaikin P. (2008). A study of the pharmacokinetic interaction of istradefylline, a novel therapeutic for Parkinson's disease, and atorvastatin. J Clin Pharmacol 48:1092-1098
-
(2008)
J Clin Pharmacol
, vol.48
, pp. 1092-1098
-
-
Rao, N.1
Dvorchik, B.2
Sussman, N.3
Wang, H.4
Yamamoto, K.5
Mori, A.6
Uchimura, T.7
Chaikin, P.8
-
36
-
-
12244301218
-
Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes
-
Shen YC, Chiou WF, Chou YC, Chen CF. (2003). Mechanisms in mediating the anti-inflammatory effects of baicalin and baicalein in human leukocytes. Eur J Pharmacol 465:171-181
-
(2003)
Eur J Pharmacol
, vol.465
, pp. 171-181
-
-
Shen, Y.C.1
Chiou, W.F.2
Chou, Y.C.3
Chen, C.F.4
-
37
-
-
0033794615
-
Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin
-
Shieh DE, Liu LT, Lin CC. (2000). Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res 20:2861-2865
-
(2000)
Anticancer Res
, vol.20
, pp. 2861-2865
-
-
Shieh, D.E.1
Liu, L.T.2
Lin, C.C.3
-
38
-
-
71549131614
-
Efflux transporter-mediated interactions with atorvastatin-interesting findings with multiple substrates: Istradefylline, verapamil, and rifampicin
-
Srinivas NR. (2009). Efflux transporter-mediated interactions with atorvastatin-interesting findings with multiple substrates: istradefylline, verapamil, and rifampicin. J Clin Pharmacol 49:1492-1493
-
(2009)
J Clin Pharmacol
, vol.49
, pp. 1492-1493
-
-
Srinivas, N.R.1
-
39
-
-
33745024058
-
Investigation of the absorption mechanisms of baicalin and baicalein in rats
-
Taiming L, Xueha J. (2006). Investigation of the absorption mechanisms of baicalin and baicalein in rats. J Pharmaceut Sci 95:1326-1333
-
(2006)
J Pharmaceut Sci
, vol.95
, pp. 1326-1333
-
-
Taiming, L.1
Xueha, J.2
-
40
-
-
33750725432
-
Determination of human plasma protein binding of baicalin by ultrafiltration and highperformance liquid chromatography
-
Tang Y, Zhu H, Zhang Y, Huang C. (2006). Determination of human plasma protein binding of baicalin by ultrafiltration and highperformance liquid chromatography. Biomed Chromatogr 20:1116-1119
-
(2006)
Biomed Chromatogr
, vol.20
, pp. 1116-1119
-
-
Tang, Y.1
Zhu, H.2
Zhang, Y.3
Huang, C.4
-
41
-
-
77954750709
-
Multiple therapeutic effects of adjunctive baicalin therapy in experimental bacterial meningitis
-
DOI:10.1007/s10753-009-9172-9
-
Tang YJ, Zhou FW, Luo ZQ, Li XZ, Yan HM, Wang MJ, Huang FR, and Yue SJ. (2009). Multiple therapeutic effects of adjunctive baicalin therapy in experimental bacterial meningitis. Inflammation [DOI:10.1007/s10753-009-9172-9].
-
(2009)
Inflammation
-
-
Tang, Y.J.1
Zhou, F.W.2
Luo, Z.Q.3
Li, X.Z.4
Yan, H.M.5
Wang, M.J.6
Huang, F.R.7
Yue, S.J.8
-
42
-
-
67349111280
-
Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen
-
Teksin ZS, Lee IJ, Nemieboka NN, Othman AA, Upreti VV, Hassan HE, Syed SS, Prisinzano TE, Eddington ND. (2009). Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen. Eur J Pharmaceut Biopharmaceut 72:471-477
-
(2009)
Eur J Pharmaceut Biopharmaceut
, vol.72
, pp. 471-477
-
-
Teksin, Z.S.1
Lee, I.J.2
Nemieboka, N.N.3
Othman, A.A.4
Upreti, V.V.5
Hassan, H.E.6
Syed, S.S.7
Prisinzano, T.E.8
Eddington, N.D.9
-
43
-
-
39749195431
-
Role of CYP2B6 in stereoselective human methadone metabolism
-
Totah RA, Sheffels P, Roberts T, Whittington D, Thummel K, Kharasch ED. (2008). Role of CYP2B6 in stereoselective human methadone metabolism. Anesthesiology 108:363-374
-
(2008)
Anesthesiology
, vol.108
, pp. 363-374
-
-
Totah, R.A.1
Sheffels, P.2
Roberts, T.3
Whittington, D.4
Thummel, K.5
Kharasch, E.D.6
-
44
-
-
34547212999
-
Bosentan is a substrate of human OATP1B1 and OATP1B3: Inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil
-
Treiber A, Schneiter R, Hausler S, Stieger B. (2007). Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil. Drug Metab Disposit 35:1400-1407
-
(2007)
Drug Metab Disposit
, vol.35
, pp. 1400-1407
-
-
Treiber, A.1
Schneiter, R.2
Hausler, S.3
Stieger, B.4
-
45
-
-
9744269966
-
Pharmacokinetics of baicalin in rats and its interactions with cyclosporine A, quinidine and SKF-525A: A microdialysis study
-
Tsai PL, Tsai TH. (2004). Pharmacokinetics of baicalin in rats and its interactions with cyclosporine A, quinidine and SKF-525A: a microdialysis study. Planta Medica 70:1069-1074
-
(2004)
Planta Medica
, vol.70
, pp. 1069-1074
-
-
Tsai, P.L.1
Tsai, T.H.2
-
46
-
-
33749453826
-
The functional role of CYP2B6 in human drug metabolism: Substrates and inhibitors in vitro, in vivo and in silico
-
Turpeinen M, Raunio H, Pelkonen O. (2006). The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico. Curr Drug Metab 7:705-714
-
(2006)
Curr Drug Metab
, vol.7
, pp. 705-714
-
-
Turpeinen, M.1
Raunio, H.2
Pelkonen, O.3
-
47
-
-
70350608018
-
Baicalin reduces mitochondrial damage in streptozotocin-induced diabetic Wistar rats
-
Waisundara VY, Hsu A, Tan BK, Hunag D. (2009). Baicalin reduces mitochondrial damage in streptozotocin-induced diabetic Wistar rats. Diabet Metab Res Rev 25:671-677
-
(2009)
Diabet Metab Res Rev
, vol.25
, pp. 671-677
-
-
Waisundara, V.Y.1
Hsu, A.2
Tan, B.K.3
Hunag, D.4
-
48
-
-
18844395901
-
Interaction of baicalin and baicalein with antibiotics in the gastrointestinal tract
-
Xing J, Chen X, Sun Y, Luan Y, Zhong D. (2005). Interaction of baicalin and baicalein with antibiotics in the gastrointestinal tract. J Pharmacy Pharmacol 57:743-750
-
(2005)
J Pharmacy Pharmacol
, vol.57
, pp. 743-750
-
-
Xing, J.1
Chen, X.2
Sun, Y.3
Luan, Y.4
Zhong, D.5
-
49
-
-
27644442245
-
Absorption and enterohepatic circulation of baicalin in rats
-
Xing J, Chen X, Zhong D. (2005). Absorption and enterohepatic circulation of baicalin in rats. Life Sci 78:140-146
-
(2005)
Life Sci
, vol.78
, pp. 140-146
-
-
Xing, J.1
Chen, X.2
Zhong, D.3
-
50
-
-
77954716992
-
Baicalin protects thymus of rats with severe acute pancreatitis
-
DOI:10.1007/s10753-009-9169-4
-
Xiping Z, Guanghua F, Jinxian H, Weihog W, Rujun X, Wei Z, Jing Y, Qijun Y, Meijuan Y, Qing W, Lini F. (2009a). Baicalin protects thymus of rats with severe acute pancreatitis. Inflammation [DOI:10.1007/s10753-009-9169-4].
-
(2009)
Inflammation
-
-
Xiping, Z.1
Guanghua, F.2
Jinxian, H.3
Weihog, W.4
Rujun, X.5
Wei, Z.6
Jing, Y.7
Qijun, Y.8
Meijuan, Y.9
Qing, W.10
Lini, F.11
-
51
-
-
77950818766
-
Influence of baicalin on TNF-alpha mRNA, caspase-3 and P-selectin expression in pancreatic tissue if rats with severe acute pancreatitis
-
Xiping Z, Hua T, Jie Z, Li C, Yang C, Bei L, Qijun Y, Jing Y, Wengqin Y, Ninnin Z. (2009b). Influence of baicalin on TNF-alpha mRNA, caspase-3 and P-selectin expression in pancreatic tissue if rats with severe acute pancreatitis. Indian J Gastroenterology 28:131-135
-
(2009)
Indian J Gastroenterology
, vol.28
, pp. 131-135
-
-
Xiping, Z.1
Hua, T.2
Jie, Z.3
Li, C.4
Yang, C.5
Bei, L.6
Qijun, Y.7
Jing, Y.8
Wengqin, Y.9
Ninnin, Z.10
-
52
-
-
33744789710
-
Simultaneous determination of baicalin, rhein and berberine in rat plasma by column-switching high-performance liquid chromatography
-
Yi L, Jian-Ping G, Xu X, Lixin D. (2006). Simultaneous determination of baicalin, rhein and berberine in rat plasma by column-switching high-performance liquid chromatography. J Chromatogr B Analyt Tech Biomed Life Sci 838:50-55
-
(2006)
J Chromatogr B Analyt Tech Biomed Life Sci
, vol.838
, pp. 50-55
-
-
Yi, L.1
Jian-Ping, G.2
Xu, X.3
Lixin, D.4
-
53
-
-
58849097045
-
Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats
-
Yue J, Peng R, Chen J, Liu Y, Dong G. (2009). Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats. Pharmaceut Res 59:112-119
-
(2009)
Pharmaceut Res
, vol.59
, pp. 112-119
-
-
Yue, J.1
Peng, R.2
Chen, J.3
Liu, Y.4
Dong, G.5
-
54
-
-
33947687624
-
Effect of baicalin and berberine on transport of nimodipine on primary cultured, rat brain the microvascular endothelial cells
-
Zhang DM, Lu HY, Xie L, Liu XD. (2007). Effect of baicalin and berberine on transport of nimodipine on primary cultured, rat brain the microvascular endothelial cells. Acta Pharmacol Sinica 28:573-578
-
(2007)
Acta Pharmacol Sinica
, vol.28
, pp. 573-578
-
-
Zhang, D.M.1
Lu, H.Y.2
Xie, L.3
Liu, X.D.4
-
55
-
-
23744497186
-
Role of intestinal first-pass metabolism of baicalin in its absorption process
-
Zhang L, Lin G, Chang Q, Zuo Z. (2005). Role of intestinal first-pass metabolism of baicalin in its absorption process. Pharmaceut Res 22:1050-1058
-
(2005)
Pharmaceut Res
, vol.22
, pp. 1050-1058
-
-
Zhang, L.1
Lin, G.2
Chang, Q.3
Zuo, Z.4
-
56
-
-
70349925379
-
Effect of baicalin on inflammatory mediatory levels and microcirculation disturbance in rats with severe acute pancreatitis
-
Zhang X, Tain H, Wu C, Ye Q, Jiang X, Chen L, Cai Y, Xu R, Yuan W. (2009). Effect of baicalin on inflammatory mediatory levels and microcirculation disturbance in rats with severe acute pancreatitis. Pancreas 38:732-738
-
(2009)
Pancreas
, vol.38
, pp. 732-738
-
-
Zhang, X.1
Tain, H.2
Wu, C.3
Ye, Q.4
Jiang, X.5
Chen, L.6
Cai, Y.7
Xu, R.8
Yuan, W.9
-
57
-
-
72449183581
-
Ocular pharmacokinetic study on baicalin in lens of rabbits following intragastric administration
-
Zhiyan J, Zhengzhong B, Liange J, Shujie Z, Kai D, Hao C, Yongbin Y, Ping L. (2010). Ocular pharmacokinetic study on baicalin in lens of rabbits following intragastric administration. Graefes Archiv Clin Exp Opthalmol 248:59-63.
-
(2010)
Graefes Archiv Clin Exp Opthalmol
, vol.248
, pp. 59-63
-
-
Zhiyan, J.1
Zhengzhong, B.2
Liange, J.3
Shujie, Z.4
Kai, D.5
Hao, C.6
Yongbin, Y.7
Ping, L.8
-
58
-
-
74949106101
-
The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells
-
Zhou QM, Wang S, Zhang H, Lu YY, Wang XF, Motoo Y, Su SB. (2009). The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells. Acta Pharmacol Sinica 30:1648-1658
-
(2009)
Acta Pharmacol Sinica
, vol.30
, pp. 1648-1658
-
-
Zhou, Q.M.1
Wang, S.2
Zhang, H.3
Lu, Y.Y.4
Wang, X.F.5
Motoo, Y.6
Su, S.B.7
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