-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108, 2005.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
38349038425
-
'Westernizing' women's risks? Breast cancer in lower-income countries
-
Porter P: 'Westernizing' women's risks? Breast cancer in lower-income countries. N Engl J Med 358: 213-216, 2008.
-
(2008)
N Engl J Med
, vol.358
, pp. 213-216
-
-
Porter, P.1
-
3
-
-
38449096482
-
Breast cancer in 2007 incidence risk assessment and risk reduction strategies
-
Joanne L: Breast cancer in 2007 incidence risk assessment and risk reduction strategies. Clin J Oncol Nurs 11: 619-622, 2007.
-
(2007)
Clin J Oncol Nurs
, vol.11
, pp. 619-622
-
-
Joanne, L.1
-
4
-
-
37849035252
-
Taxane-based combinations as adjuvant chemotherapy of early breast cancer: A meta-analysis of randomized trials
-
De Laurentiis M, Cancello G, D'Agostino D, et al: Taxane-based combinations as adjuvant chemotherapy of early breast cancer: a meta-analysis of randomized trials. J Clin Oncol 26: 44-53, 2008.
-
(2008)
J Clin Oncol
, vol.26
, pp. 44-53
-
-
De Laurentiis, M.1
Cancello, G.2
D'Agostino, D.3
-
5
-
-
42249083269
-
Weekly paclitaxel in the adjuvant treatment of breast cancer
-
Sparano JA, Wang M, Martino S, et al: Weekly paclitaxel in the adjuvant treatment of breast cancer. N Engl J Med 358: 1663-1671, 2008.
-
(2008)
N Engl J Med
, vol.358
, pp. 1663-1671
-
-
Sparano, J.A.1
Wang, M.2
Martino, S.3
-
7
-
-
0030946109
-
Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosphila and yeast Ipl1
-
Kimura M, Kotani S, Hattori T, et al: Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosphila and yeast Ipl1. J Biol Chem 272: 13766-13771, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 13766-13771
-
-
Kimura, M.1
Kotani, S.2
Hattori, T.3
-
8
-
-
0037117408
-
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis
-
Berdnik D and Knoblich JA: Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr Biol 12: 640-647, 2002.
-
(2002)
Curr Biol
, vol.12
, pp. 640-647
-
-
Berdnik, D.1
Knoblich, J.A.2
-
9
-
-
0037017398
-
Drosophila Aurora a kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
-
Giet R, McLean D, Descamps S, Lee MJ, Raff JW, Prigent C and Glover DM: Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J Cell Biol 156: 437-451, 2002.
-
(2002)
J Cell Biol
, vol.156
, pp. 437-451
-
-
Giet, R.1
McLean, D.2
Descamps, S.3
Lee, M.J.4
Raff, J.W.5
Prigent, C.6
Glover, D.M.7
-
10
-
-
0035945342
-
Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans
-
Hannak E, Kirkham M, Hyman AA and Oegema K: Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. J Cell Biol 155: 1109-1116, 2001.
-
(2001)
J Cell Biol
, vol.155
, pp. 1109-1116
-
-
Hannak, E.1
Kirkham, M.2
Hyman, A.A.3
Oegema, K.4
-
11
-
-
0032100685
-
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
-
Bischoff JR, Anderson L, Zhu Y, et al: A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. EMBO J 17: 3052-3065, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 3052-3065
-
-
Bischoff, J.R.1
Anderson, L.2
Zhu, Y.3
-
12
-
-
14944338969
-
Aurora kinases: Therapeutic potential
-
Montembault E and Prigent C: Aurora kinases: therapeutic potential. Drugs Future 30: 29, 2005.
-
(2005)
Drugs Future
, vol.30
, pp. 29
-
-
Montembault, E.1
Prigent, C.2
-
13
-
-
51649095478
-
Expression of Aurora a (but not Aurora B) is predictive of survival in breast cancer
-
Nadler Y, Camp RL, Schwartz C, Rimm DL, Kluger HM and Kluger Y: Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer. Clin Cancer Res 14: 4455-4462, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4455-4462
-
-
Nadler, Y.1
Camp, R.L.2
Schwartz, C.3
Rimm, D.L.4
Kluger, H.M.5
Kluger, Y.6
-
14
-
-
6044248871
-
Therapeutic potential of RNA interference
-
Mario Stevenson: Therapeutic potential of RNA interference. N Engl J Med 351: 1772-1777, 2004.
-
(2004)
N Engl J Med
, vol.351
, pp. 1772-1777
-
-
Stevenson, M.1
-
15
-
-
33748529639
-
RNAi therapy for neuro-degenerative diseases
-
Review
-
Boudreau RL and Davidson BL: RNAi therapy for neuro-degenerative diseases (Review). Curr Top Dev Biol 75: 73-92, 2006.
-
(2006)
Curr Top Dev Biol
, vol.75
, pp. 73-92
-
-
Boudreau, R.L.1
Davidson, B.L.2
-
16
-
-
33645139836
-
Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disorders
-
Campochiaro PA: Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disorders. Gene Ther 13: 559-562, 2006.
-
(2006)
Gene Ther
, vol.13
, pp. 559-562
-
-
Campochiaro, P.A.1
-
17
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee NS, Dohjima T, Bauer G, et al: Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 20, 500-505, 2002.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
-
18
-
-
16844366286
-
RNA interference targeting Aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells
-
Hata T, Furukawa T, Sunamura M, et al: RNA interference targeting Aurora kinase A suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells. Cancer Res 65: 2899-2905, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 2899-2905
-
-
Hata, T.1
Furukawa, T.2
Sunamura, M.3
-
19
-
-
70149113455
-
Improved therapeutic efficacy against murine carcinoma by combining honokiol with gene therapy of PNAS-4, a novel pro-apoptotic gene
-
Yuan Z, Liu H, Yan F, et al: Improved therapeutic efficacy against murine carcinoma by combining honokiol with gene therapy of PNAS-4, a novel pro-apoptotic gene. Cancer Sci 100: 1757-1766, 2009.
-
(2009)
Cancer Sci
, vol.100
, pp. 1757-1766
-
-
Yuan, Z.1
Liu, H.2
Yan, F.3
-
21
-
-
33846988313
-
Roles of aurora kinases in mitosis and tumorigenesis
-
Fu J, Bian M, Jiang Q and Zhang C: Roles of aurora kinases in mitosis and tumorigenesis. Mol Cancer Res 5: 1-10, 2007.
-
(2007)
Mol Cancer Res
, vol.5
, pp. 1-10
-
-
Fu, J.1
Bian, M.2
Jiang, Q.3
Zhang, C.4
-
22
-
-
0141429171
-
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
-
Hirota T, Kunitoku N, Sasayama T, et al: Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 114: 585-598, 2003.
-
(2003)
Cell
, vol.114
, pp. 585-598
-
-
Hirota, T.1
Kunitoku, N.2
Sasayama, T.3
-
23
-
-
0037135979
-
Human TPX2 is required for targeting Aurora-A kinase to the spindle
-
Kufer TA, Silljé HH, Körner R, Gruss OJ, Meraldi P and Nigg EA: Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol 158: 617-623, 2002.
-
(2002)
J Cell Biol
, vol.158
, pp. 617-623
-
-
Kufer, T.A.1
Silljé, H.H.2
Körner, R.3
Gruss, O.J.4
Meraldi, P.5
Nigg, E.A.6
-
24
-
-
50849139592
-
Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells
-
Katayama H, Sasai K, Kloc M, Brinkley BR and Sen S: Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells. Cell Cycle 7: 2691-2704, 2008.
-
(2008)
Cell Cycle
, vol.7
, pp. 2691-2704
-
-
Katayama, H.1
Sasai, K.2
Kloc, M.3
Brinkley, B.R.4
Sen, S.5
-
25
-
-
33751085368
-
Overexpression of aurora kinase a in mouse mammary epithelium induces genetic instability preceding mammary tumor formation
-
Wang X, Zhou YX, Qiao W, Tominaga Y, Ouchi M, Ouchi T and Deng CX: Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation. Oncogene 25: 7148-7158, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 7148-7158
-
-
Wang, X.1
Zhou, Y.X.2
Qiao, W.3
Tominaga, Y.4
Ouchi, M.5
Ouchi, T.6
Deng, C.X.7
-
26
-
-
53849129538
-
Down-regulation of Aurora-A overrides estrogen-mediated growth and chemoresistance in breast cancer cells
-
Lee HH, Zhu Y, Govindasamy KM and Gopalan G: Down-regulation of Aurora-A overrides estrogen-mediated growth and chemoresistance in breast cancer cells. Endocr Relat Cancer 15: 765-775, 2008.
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 765-775
-
-
Lee, H.H.1
Zhu, Y.2
Govindasamy, K.M.3
Gopalan, G.4
-
27
-
-
35748945448
-
The role of Aurora-A inhibitors in cancer therapy
-
Agnese V, Bazan V, Fiorentino FP, et al: The role of Aurora-A inhibitors in cancer therapy. Ann Oncol 18: vi47-vi52, 2007.
-
(2007)
Ann Oncol
, vol.18
-
-
Agnese, V.1
Bazan, V.2
Fiorentino, F.P.3
-
28
-
-
64349120831
-
Structure-based drug design of novel Aurora kinase a inhibitors: Structural basis for potency and specificity
-
Coumar MS, Leou JS, Shukla P, et al: Structure-based drug design of novel Aurora kinase A inhibitors: structural basis for potency and specificity. J Med Chem 52: 1050-1062, 2009.
-
(2009)
J Med Chem
, vol.52
, pp. 1050-1062
-
-
Coumar, M.S.1
Leou, J.S.2
Shukla, P.3
-
29
-
-
43949138612
-
Development and biological evaluation of a novel Aurora a kinase inhibitor pharmacophore modelling and virtual screening for identification of new Aurora-A kinase inhibitors
-
Deng XQ, Wang HY, Zhao YL, et al: Development and biological evaluation of a novel Aurora A kinase inhibitor pharmacophore modelling and virtual screening for identification of new Aurora-A kinase inhibitors. Chem Biol Drug Des 71: 533-539, 2008.
-
(2008)
Chem Biol Drug des
, vol.71
, pp. 533-539
-
-
Deng, X.Q.1
Wang, H.Y.2
Zhao, Y.L.3
-
30
-
-
0036245628
-
U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells
-
Miyagishi M and Taira K: U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol 20: 497-500, 2002.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 497-500
-
-
Miyagishi, M.1
Taira, K.2
-
31
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
Paul CP, Good PD, Winer I and Engelke DR: Effective expression of small interfering RNA in human cells. Nat Biotechnol 20: 505-508, 2002.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 505-508
-
-
Paul, C.P.1
Good, P.D.2
Winer, I.3
Engelke, D.R.4
-
32
-
-
21344457432
-
RNA interference: From gene silencing to gene-specific therapeutics
-
Leung RK and Whittaker PA: RNA interference: from gene silencing to gene-specific therapeutics. Pharmacol Ther 107: 222-239, 2005.
-
(2005)
Pharmacol Ther
, vol.107
, pp. 222-239
-
-
Leung, R.K.1
Whittaker, P.A.2
-
33
-
-
1342342857
-
Strategies for generation of an SiRNA expression library directed against the human genome
-
Miyagishi M and Taira K: Strategies for generation of an SiRNA expression library directed against the human genome. Oligonucleotides 13: 325-333, 2003.
-
(2003)
Oligonucleotides
, vol.13
, pp. 325-333
-
-
Miyagishi, M.1
Taira, K.2
-
34
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas D, Lerner C, Burchard J, et al: Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol 23: 227-231, 2005.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
-
35
-
-
15444369907
-
Simple and efficient DNA vector-based RNAi systems in mammalian cells
-
Wu MT, Wu RH, Hung CF, Cheng TL, Tsai WH and Chang WT: Simple and efficient DNA vector-based RNAi systems in mammalian cells. Biochem Biophys Res Commun 330: 53-59, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.330
, pp. 53-59
-
-
Wu, M.T.1
Wu, R.H.2
Hung, C.F.3
Cheng, T.L.4
Tsai, W.H.5
Chang, W.T.6
-
37
-
-
37049000352
-
Enhancement of radiation response by inhibition of Aurora-A kinase using siRNA or a selective Aurora kinase inhibitor PHA680632 in p53-deficient cancer cells
-
Tao Y, Zhang P, Frascogna V, Lecluse Y, Auperin A, Bourhis J and Deutsch E: Enhancement of radiation response by inhibition of Aurora-A kinase using siRNA or a selective Aurora kinase inhibitor PHA680632 in p53-deficient cancer cells. Br J Cancer 97: 1664-1672, 2007.
-
(2007)
Br J Cancer
, vol.97
, pp. 1664-1672
-
-
Tao, Y.1
Zhang, P.2
Frascogna, V.3
Lecluse, Y.4
Auperin, A.5
Bourhis, J.6
Deutsch, E.7
-
38
-
-
39749106551
-
Aurora a kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells
-
Evans R, Naber C, Steffler T, et al: Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells. Leuk Lymphoma 49: 559-569, 2008.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 559-569
-
-
Evans, R.1
Naber, C.2
Steffler, T.3
-
39
-
-
33749605644
-
Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells
-
Yang H, He L, Kruk P, Nicosia SV and Cheng JQ: Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells. Int J Cancer 119: 2304-2312, 2006.
-
(2006)
Int J Cancer
, vol.119
, pp. 2304-2312
-
-
Yang, H.1
He, L.2
Kruk, P.3
Nicosia, S.V.4
Cheng, J.Q.5
-
40
-
-
33646154663
-
Overexpression of Aurora-A kinase promotes tumor cell proliferation and inhibits apoptosis in esophageal squamous cell carcinoma cell line
-
Wang XX, Liu R, Jin SQ, Fan FY and Zhan QM: Overexpression of Aurora-A kinase promotes tumor cell proliferation and inhibits apoptosis in esophageal squamous cell carcinoma cell line. Cell Res 16: 356-366, 2006.
-
(2006)
Cell Res
, vol.16
, pp. 356-366
-
-
Wang, X.X.1
Liu, R.2
Jin, S.Q.3
Fan, F.Y.4
Zhan, Q.M.5
-
41
-
-
71749103630
-
Comparative immunohistochemical analysis of aurora-A and aurora-B expression in human glioblastomas. Associations with proliferative activity and clinicopathological features
-
Samaras V, Stamatelli A, Samaras E, et al: Comparative immunohistochemical analysis of aurora-A and aurora-B expression in human glioblastomas. Associations with proliferative activity and clinicopathological features. Pathol Res Pract 205: 765-773, 2009.
-
(2009)
Pathol Res Pract
, vol.205
, pp. 765-773
-
-
Samaras, V.1
Stamatelli, A.2
Samaras, E.3
-
42
-
-
0032552426
-
Biodistribution and gene expression of lipid/plasmid complexes after systemic administration
-
Mahato RI, Anwer K, Tagliaferri F, et al: Biodistribution and gene expression of lipid/plasmid complexes after systemic administration. Hum Gene Ther 9: 2083-2099, 1998.
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2083-2099
-
-
Mahato, R.I.1
Anwer, K.2
Tagliaferri, F.3
-
43
-
-
38349178008
-
In vivo comparative study of lipid/DNA complexes with different in vitro serum stability: Effects on biodistribution and tumor accumulation
-
Zhang Y, Bradshaw-Pierce EL, Delille A, Gustafson DL and Anchordoquy TJ: In vivo comparative study of lipid/DNA complexes with different in vitro serum stability: Effects on biodistribution and tumor accumulation. J Pharm Sci 97: 237-250, 2008.
-
(2008)
J Pharm Sci
, vol.97
, pp. 237-250
-
-
Zhang, Y.1
Bradshaw-Pierce, E.L.2
Delille, A.3
Gustafson, D.L.4
Anchordoquy, T.J.5
|