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Volumn 6, Issue 4, 2010, Pages 195-213

Transplantation of adipose tissue and stem cells: Role in metabolism and disease

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Indexed keywords

RECOMBINANT LEPTIN;

EID: 77950296018     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2010.20     Document Type: Review
Times cited : (258)

References (197)
  • 1
    • 0030989520 scopus 로고    scopus 로고
    • Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study
    • Carey, v. J. et al. Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses' Health Study. Am. J. Epidemiol. 145, 614-619 (1997).
    • (1997) Am. J. Epidemiol. , vol.145 , pp. 614-619
    • Carey, V.J.1
  • 2
    • 15744387573 scopus 로고    scopus 로고
    • Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men
    • wang, Y., Rimm, e. B., Stampfer, M. J., willett, w. C. &Hu, F. B. Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am. J. Clin. Nutr. 81, 555-563 (2005).
    • (2005) Am. J. Clin. Nutr. , vol.81 , pp. 555-563
    • Wang, Y.1    Rimm, E.B.2    Stampfer, M.J.3    Willett, W.C.4    Hu, F.B.5
  • 3
    • 41649097735 scopus 로고    scopus 로고
    • Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: Sixteen years of follow-up in US women
    • Zhang, C., Rexrode, K. M., van Dam, R. M., Li, T. Y. &Hu, F. B. Abdominal obesity and the risk of all-cause, cardiovascular, and cancer mortality: sixteen years of follow-up in US women. Circulation 117, 1658-1667 (2008).
    • (2008) Circulation , vol.117 , pp. 1658-1667
    • Zhang, C.1    Rexrode, K.M.2    Van Dam, R.M.3    Li, T.Y.4    Hu, F.B.5
  • 4
    • 0034255069 scopus 로고    scopus 로고
    • Adiposity and mortality in men
    • Baik, I. et al. Adiposity and mortality in men. Am. J. Epidemiol. 152, 264-271 (2000).
    • (2000) Am. J. Epidemiol , vol.152 , pp. 264-271
    • Baik, I.1
  • 5
    • 56249131806 scopus 로고    scopus 로고
    • General and abdominal adiposity and risk of death in europe
    • Pischon, T. et al. General and abdominal adiposity and risk of death in europe. N. Engl. J. Med. 359, 2105-2120 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 2105-2120
    • Pischon, T.1
  • 6
    • 0036179818 scopus 로고    scopus 로고
    • A pilot study of long-term effects of a novel obesity treatment: Omentectomy in connection with adjustable gastric banding
    • Thorne, A., Lonnqvist, F., Apelman, J., Hellers, G. &Arner, P. A pilot study of long-term effects of a novel obesity treatment: omentectomy in connection with adjustable gastric banding. Int. J. Obes. Relat. Metab. Disord. 26, 193-199 (2002).
    • (2002) Int. J. Obes. Relat. Metab. Disord. , vol.26 , pp. 193-199
    • Thorne, A.1    Lonnqvist, F.2    Apelman, J.3    Hellers, G.4    Arner, P.5
  • 7
    • 0344301899 scopus 로고    scopus 로고
    • Effect of lipectomy on growth and development of hyperinsulinemia and hyperlipidemia in the Zucker rat
    • Liszka, T. G., Dellon, A. L., Im, M., Angel, M. F. &Plotnick, L. effect of lipectomy on growth and development of hyperinsulinemia and hyperlipidemia in the Zucker rat. Plast. Reconstr. Surg. 102, 1122-1127 (1998).
    • (1998) Plast. Reconstr. Surg. , vol.102 , pp. 1122-1127
    • Liszka, T.G.1    Dellon, A.L.2    Im, M.3    Angel, M.F.4    Plotnick, L.5
  • 8
    • 69949106011 scopus 로고    scopus 로고
    • Role of visceral adipose tissue in aging
    • Huffman, D. M. &Barzilai, N. Role of visceral adipose tissue in aging. Biochim. Biophys. Acta 1790, 1117-1123 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 1117-1123
    • Huffman, D.M.1    Barzilai, N.2
  • 9
    • 63049111105 scopus 로고    scopus 로고
    • Greater omentectomy improves insulin sensitivity in nonobese dogs
    • Lottati, M., Kolka, C. M., Stefanovski, D., Kirkman, e. L. &Bergman, R. N. Greater omentectomy improves insulin sensitivity in nonobese dogs. Obesity 17, 674-680 (2009).
    • (2009) Obesity , vol.17 , pp. 674-680
    • Lottati, M.1    Kolka, C.M.2    Stefanovski, D.3    Kirkman, E.L.4    Bergman, R.N.5
  • 10
    • 43449113550 scopus 로고    scopus 로고
    • Visceral adipose tissue modulates mammalian longevity
    • Muzumdar, R. et al. visceral adipose tissue modulates mammalian longevity. Aging Cell 7, 438-440 (2008).
    • (2008) Aging Cell , vol.7 , pp. 438-440
    • Muzumdar, R.1
  • 11
    • 0031087638 scopus 로고    scopus 로고
    • Relationship of anterior and posterior subcutaneous abdominal fat to insulin sensitivity in nondiabetic men
    • Misra, A. et al. Relationship of anterior and posterior subcutaneous abdominal fat to insulin sensitivity in nondiabetic men. Obes. Res. 5, 93-99 (1997).
    • (1997) Obes. Res. , vol.5 , pp. 93-99
    • Misra, A.1
  • 12
    • 0038811794 scopus 로고    scopus 로고
    • Associations of hip and thigh circumferences independent of waist circumference with the incidence of type 2 diabetes: The Hoorn Study
    • Snijder, M. B. et al. Associations of hip and thigh circumferences independent of waist circumference with the incidence of type 2 diabetes: the Hoorn Study. Am. J. Clin. Nutr. 77, 1192-1197 (2003).
    • (2003) Am. J. Clin. Nutr. , vol.77 , pp. 1192-1197
    • Snijder, M.B.1
  • 13
    • 85047696871 scopus 로고    scopus 로고
    • Glucose uptake and insulin action in human adipose tissue--influence of BMI, anatomical depot and body fat distribution
    • Stolic, M. et al. Glucose uptake and insulin action in human adipose tissue--influence of BMI, anatomical depot and body fat distribution. Int. J. Obes. Relat. Metab. Disord. 26, 17-23 (2002).
    • (2002) Int. J. Obes. Relat. Metab. Disord. , vol.26 , pp. 17-23
    • Stolic, M.1
  • 14
    • 0037382301 scopus 로고    scopus 로고
    • Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women
    • Tanko, L. B., Bagger, Y. Z., Alexandersen, P., Larsen, P. J. &Christiansen, C. Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women. Circulation 107, 1626-1631 (2003).
    • (2003) Circulation , vol.107 , pp. 1626-1631
    • Tanko, L.B.1    Bagger, Y.Z.2    Alexandersen, P.3    Larsen, P.J.4    Christiansen, C.5
  • 15
    • 2942526828 scopus 로고    scopus 로고
    • Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
    • Klein, S. et al. Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N. Engl. J. Med. 350, 2549-2557 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 2549-2557
    • Klein, S.1
  • 16
    • 43349096393 scopus 로고    scopus 로고
    • The effects of liposuction removal of subcutaneous abdominal fat on lipid metabolism are independent of insulin sensitivity in normal-overweight individuals
    • Ybarra, J. et al. The effects of liposuction removal of subcutaneous abdominal fat on lipid metabolism are independent of insulin sensitivity in normal-overweight individuals. Obes. Surg. 18, 408-414 (2008).
    • (2008) Obes. Surg. , vol.18 , pp. 408-414
    • Ybarra, J.1
  • 17
    • 33750596340 scopus 로고    scopus 로고
    • Fat depot-specific characteristics are retained in strains derived from single human preadipocytes
    • Tchkonia, T. et al. Fat depot-specific characteristics are retained in strains derived from single human preadipocytes. Diabetes 55, 2571-2578 (2006).
    • (2006) Diabetes , vol.55 , pp. 2571-2578
    • Tchkonia, T.1
  • 18
    • 33846032618 scopus 로고    scopus 로고
    • Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns
    • Tchkonia, T. et al. Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns. Am. J. Physiol. Endocrinol. Metab. 292, e298-e307 (2007).
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.292
    • Tchkonia, T.1
  • 19
    • 0032908594 scopus 로고    scopus 로고
    • Insulin regulation of regional free fatty acid metabolism
    • Meek, S. e., Nair, K. S. &Jensen, M. D. Insulin regulation of regional free fatty acid metabolism. Diabetes 48, 10-14 (1999).
    • (1999) Diabetes , vol.48 , pp. 10-14
    • Meek, S.E.1    Nair, K.S.2    Jensen, M.D.3
  • 20
    • 0038341767 scopus 로고    scopus 로고
    • Do regional differences in adipocyte biology provide new pathophysiological insights?
    • Lafontan, M. &Berlan, M. Do regional differences in adipocyte biology provide new pathophysiological insights? Trends Pharmacol. Sci. 24, 276-283 (2003).
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 276-283
    • Lafontan, M.1    Berlan, M.2
  • 21
    • 58149528712 scopus 로고    scopus 로고
    • Advances in adipose tissue metabolism
    • Lafontan, M. Advances in adipose tissue metabolism. Int. J. Obes. 32 (Suppl. 7), S39-S51 (2008).
    • (2008) Int. J. Obes. , vol.32 , Issue.SUPPL. 7
    • Lafontan, M.1
  • 22
    • 0032793212 scopus 로고    scopus 로고
    • Regional postprandial fatty acid metabolism in different obesity phenotypes
    • Guo, Z., Hensrud, D. D., Johnson, C. M. &Jensen, M. D. Regional postprandial fatty acid metabolism in different obesity phenotypes. Diabetes 48, 1586-1592 (1999).
    • (1999) Diabetes , vol.48 , pp. 1586-1592
    • Guo, Z.1    Hensrud, D.D.2    Johnson, C.M.3    Jensen, M.D.4
  • 23
    • 55949114663 scopus 로고    scopus 로고
    • Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: Visceral adipose tissue production and liver metabolism
    • Girard, J. &Lafontan, M. Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: visceral adipose tissue production and liver metabolism. Diabetes Metab. 34, 439-445 (2008).
    • (2008) Diabetes Metab. , vol.34 , pp. 439-445
    • Girard, J.1    Lafontan, M.2
  • 24
    • 33746449629 scopus 로고    scopus 로고
    • The metabolic syndrome is frequent in Klinefelter's syndrome and is associated with abdominal obesity and hypogonadism
    • Bojesen, A. et al. The metabolic syndrome is frequent in Klinefelter's syndrome and is associated with abdominal obesity and hypogonadism. Diabetes Care 29, 1591-1598 (2006).
    • (2006) Diabetes Care , vol.29 , pp. 1591-1598
    • Bojesen, A.1
  • 25
    • 7044250697 scopus 로고    scopus 로고
    • Direct effects of sex steroid hormones on adipose tissues and obesity
    • Mayes, J. S. &watson, G. H. Direct effects of sex steroid hormones on adipose tissues and obesity. Obes. Rev. 5, 197-216 (2004).
    • (2004) Obes. Rev. , vol.5 , pp. 197-216
    • Mayes, J.S.1    Watson, G.H.2
  • 26
    • 64649104155 scopus 로고    scopus 로고
    • Sex and depot differences in adipocyte insulin sensitivity and glucose metabolism
    • Macotela, Y., Boucher, J., Tran, T. T. &Kahn, C. R. Sex and depot differences in adipocyte insulin sensitivity and glucose metabolism. Diabetes 58, 803-812 (2009).
    • (2009) Diabetes , vol.58 , pp. 803-812
    • MacOtela, Y.1    Boucher, J.2    Tran, T.T.3    Kahn, C.R.4
  • 29
    • 33750042898 scopus 로고    scopus 로고
    • Complex actions of sex steroids in adipose tissue, the cardiovascular system, and brain: Insights from basic science and clinical studies
    • Turgeon, J. L., Carr, M. C., Maki, P. M., Mendelsohn, M. e. &wise, P. M. Complex actions of sex steroids in adipose tissue, the cardiovascular system, and brain: Insights from basic science and clinical studies. Endocr. Rev. 27, 575-605 (2006).
    • (2006) Endocr. Rev. , vol.27 , pp. 575-605
    • Turgeon, J.L.1    Carr, M.C.2    Maki, P.M.3    Mendelsohn, M.E.4    Wise, P.M.5
  • 30
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi, T. et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7, 941-946 (2001).
    • (2001) Nat. Med. , vol.7 , pp. 941-946
    • Yamauchi, T.1
  • 31
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg, A. H., Combs, T. P., Du, X., Brownlee, M. &Scherer, P. e. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat. Med. 7, 947-953 (2001).
    • (2001) Nat. Med. , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 32
    • 0037135523 scopus 로고    scopus 로고
    • Disruption of adiponectin causes insulin resistance and neointimal formation
    • Kubota, N. et al. Disruption of adiponectin causes insulin resistance and neointimal formation. J. Biol. Chem. 277, 25863-25866 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 25863-25866
    • Kubota, N.1
  • 33
    • 39849088585 scopus 로고    scopus 로고
    • Is there any association between subcutaneous adipose tissue area and plasma total and high molecular weight adiponectin levels?
    • Fujikawa, R., Ito, C., Nakashima, R., Orita, Y. &Ohashi, N. Is there any association between subcutaneous adipose tissue area and plasma total and high molecular weight adiponectin levels? Metabolism 57, 506-510 (2008).
    • (2008) Metabolism , vol.57 , pp. 506-510
    • Fujikawa, R.1    Ito, C.2    Nakashima, R.3    Orita, Y.4    Ohashi, N.5
  • 34
    • 67650475976 scopus 로고    scopus 로고
    • Visceral and subcutaneous adiposity and adiponectin in middle-aged Japanese men: The eRA JUMP study
    • Nakamura, Y. et al. visceral and subcutaneous adiposity and adiponectin in middle-aged Japanese men: the eRA JUMP study. Obesity 17, 1269-1273 (2009).
    • (2009) Obesity , vol.17 , pp. 1269-1273
    • Nakamura, Y.1
  • 35
    • 37149051275 scopus 로고    scopus 로고
    • Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training
    • Bluher, M. et al. Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training. Diabetes Care 30, 3110-3115 (2007).
    • (2007) Diabetes Care , vol.30 , pp. 3110-3115
    • Bluher, M.1
  • 36
    • 34848872799 scopus 로고    scopus 로고
    • Obesity-associated improvements in metabolic profile through expansion of adipose tissue
    • Kim, J. Y. et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 117, 2621-2637 (2007).
    • (2007) J. Clin. Invest. , vol.117 , pp. 2621-2637
    • Kim, J.Y.1
  • 37
    • 0036134187 scopus 로고    scopus 로고
    • Resistin and obesity-associated insulin resistance
    • Steppan, C. M. &Lazar, M. A. Resistin and obesity-associated insulin resistance. Trends Endocrinol. Metab. 13, 18-23 (2002).
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 18-23
    • Steppan, C.M.1    Lazar, M.A.2
  • 38
    • 22944434929 scopus 로고    scopus 로고
    • Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
    • Yang, Q. et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 436, 356-362 (2005).
    • (2005) Nature , vol.436 , pp. 356-362
    • Yang, Q.1
  • 39
    • 0036090282 scopus 로고    scopus 로고
    • Increased resistin gene and protein expression in human abdominal adipose tissue
    • McTernan, P. G. et al. Increased resistin gene and protein expression in human abdominal adipose tissue. J. Clin. Endocrinol. Metab. 87, 2407-2410 (2002).
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 2407-2410
    • McTernan, P.G.1
  • 40
    • 34347233419 scopus 로고    scopus 로고
    • Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass
    • Kloting, N. et al. Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass. Cell Metab. 6, 79-87 (2007).
    • (2007) Cell Metab. , vol.6 , pp. 79-87
    • Kloting, N.1
  • 41
    • 33646271627 scopus 로고    scopus 로고
    • Evidence for a role of developmental genes in the origin of obesity and body fat distribution
    • Gesta, S. et al. evidence for a role of developmental genes in the origin of obesity and body fat distribution. Proc. Natl Acad. Sci. USA 103, 6676-6681 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 6676-6681
    • Gesta, S.1
  • 42
    • 34347353314 scopus 로고    scopus 로고
    • The generation of adipocytes by the neural crest
    • Billon, N. et al. The generation of adipocytes by the neural crest. Development 134, 2283-2292 (2007).
    • (2007) Development , vol.134 , pp. 2283-2292
    • Billon, N.1
  • 43
    • 6344260341 scopus 로고    scopus 로고
    • A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men
    • vohl, M. C. et al. A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men. Obes. Res. 12, 1217-1222 (2004).
    • (2004) Obes. Res. , vol.12 , pp. 1217-1222
    • Vohl, M.C.1
  • 44
    • 7044262828 scopus 로고    scopus 로고
    • A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
    • Yeo, G. S. et al. A de novo mutation affecting human TrkB associated with severe obesity and developmental delay. Nat. Neurosci. 7, 1187-1189 (2004).
    • (2004) Nat. Neurosci. , vol.7 , pp. 1187-1189
    • Yeo, G.S.1
  • 45
    • 62249144948 scopus 로고    scopus 로고
    • MicroRNA expression in human omental and subcutaneous adipose tissue
    • Kloting, N. et al. MicroRNA expression in human omental and subcutaneous adipose tissue. PLoS One 4, e4699 (2009).
    • (2009) PLoS One , vol.4
    • Kloting, N.1
  • 46
    • 21244474452 scopus 로고    scopus 로고
    • Adipose tissues as an ancestral immune organ: Site-specific change in obesity
    • Caspar-Bauguil, S. et al. Adipose tissues as an ancestral immune organ: site-specific change in obesity. FEBS Lett. 579, 3487-3492 (2005).
    • (2005) FEBS Lett. , vol.579 , pp. 3487-3492
    • Caspar-Bauguil, S.1
  • 47
    • 33745234778 scopus 로고    scopus 로고
    • Weight-dependent changes of immune system in adipose tissue: Importance of leptin
    • Caspar-Bauguil, S. et al. weight-dependent changes of immune system in adipose tissue: importance of leptin. Exp. Cell. Res. 312, 2195-2202 (2006).
    • (2006) Exp. Cell. Res. , vol.312 , pp. 2195-2202
    • Caspar-Bauguil, S.1
  • 48
    • 70349150518 scopus 로고    scopus 로고
    • Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissue
    • O'Rourke, R. w. et al. Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissue. Int. J. Obes. 33, 978-990 (2009).
    • (2009) Int. J. Obes. , vol.33 , pp. 978-990
    • O'Rourke, R.W.1
  • 49
    • 17844393870 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): Implication of macrophages resident in the at
    • Bruun, J. M., Lihn, A. S., Pedersen, S. B. &Richelsen, B. Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT. J. Clin. Endocrinol. Metab. 90, 2282-2289 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 2282-2289
    • Bruun, J.M.1    Lihn, A.S.2    Pedersen, S.B.3    Richelsen, B.4
  • 50
    • 0033853610 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity
    • Alessi, M. C. et al. Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. Diabetes 49, 1374-1380 (2000).
    • (2000) Diabetes , vol.49 , pp. 1374-1380
    • Alessi, M.C.1
  • 51
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
    • Fried, S. K., Bunkin, D. A. &Greenberg, A. S. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J. Clin. Endocrinol. Metab. 83, 847-850 (1998).
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 52
    • 0348048487 scopus 로고    scopus 로고
    • Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue
    • Bruun, J. M. et al. Higher production of IL-8 in visceral vs. subcutaneous adipose tissue. Implication of nonadipose cells in adipose tissue. Am. J. Physiol. Endocrinol. Metab. 286, e8-e13 (2004).
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.286
    • Bruun, J.M.1
  • 53
    • 14644419628 scopus 로고    scopus 로고
    • Adipose tissue is a regulated source of interleukin-10
    • Juge-Aubry, C. e. et al. Adipose tissue is a regulated source of interleukin-10. Cytokine 29, 270-274 (2005).
    • (2005) Cytokine , vol.29 , pp. 270-274
    • Juge-Aubry, C.E.1
  • 54
    • 0036309971 scopus 로고    scopus 로고
    • Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists
    • Sewter, C. P., Blows, F., vidal-Puig, A. &O'Rahilly, S. Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists. Diabetes 51, 718-723 (2002).
    • (2002) Diabetes , vol.51 , pp. 718-723
    • Sewter, C.P.1    Blows, F.2    Vidal-Puig, A.3    O'Rahilly, S.4
  • 55
    • 0034750654 scopus 로고    scopus 로고
    • Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation--double-blind placebo-controlled trial
    • Nakamura, T. et al. Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation--double-blind placebo-controlled trial. Diabetes Res. Clin. Pract. 54, 181-190 (2001).
    • (2001) Diabetes Res. Clin. Pract. , vol.54 , pp. 181-190
    • Nakamura, T.1
  • 56
    • 50649102114 scopus 로고    scopus 로고
    • Subcutaneous abdominal adipose tissue subcompartments: Potential role in rosiglitazone effects
    • walker, G. e. et al. Subcutaneous abdominal adipose tissue subcompartments: potential role in rosiglitazone effects. Obesity 16, 1983-1991 (2008).
    • (2008) Obesity , vol.16 , pp. 1983-1991
    • Walker, G.E.1
  • 57
    • 72049127515 scopus 로고    scopus 로고
    • Mechanisms of adipose tissue redistribution with rosiglitazone treatment in various adipose depots
    • Kang, J. G. et al. Mechanisms of adipose tissue redistribution with rosiglitazone treatment in various adipose depots. Metabolism 59, 46-53 (2010).
    • (2010) Metabolism , vol.59 , pp. 46-53
    • Kang, J.G.1
  • 58
    • 56049087969 scopus 로고    scopus 로고
    • Adiponectin secretion and response to pioglitazone is depot dependent in cultured human adipose tissue
    • Phillips, S. A., Ciaraldi, T. P., Oh, D. K., Savu, M. K. &Henry, R. R. Adiponectin secretion and response to pioglitazone is depot dependent in cultured human adipose tissue. Am. J. Physiol. Endocrinol. Metab. 295, e842-e850 (2008).
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295
    • Phillips, S.A.1    Ciaraldi, T.P.2    Oh, D.K.3    Savu, M.K.4    Henry, R.R.5
  • 59
    • 33751181461 scopus 로고    scopus 로고
    • Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes
    • Bodles, A. M. et al. Pioglitazone increases secretion of high-molecular-weight adiponectin from adipocytes. Am. J. Physiol. Endocrinol. Metab. 291, e1100-e1105 (2006).
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.291
    • Bodles, A.M.1
  • 60
    • 0028865142 scopus 로고
    • Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
    • Kopecky, J., Clarke, G., enerback, S., Spiegelman, B. &Kozak, L. P. expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity. J. Clin. Invest. 96, 2914-2923 (1995).
    • (1995) J. Clin. Invest. , vol.96 , pp. 2914-2923
    • Kopecky, J.1    Clarke, G.2    Enerback, S.3    Spiegelman, B.4    Kozak, L.P.5
  • 61
    • 58749091645 scopus 로고    scopus 로고
    • UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality
    • Feldmann, H. M., Golozoubova, v., Cannon, B. &Nedergaard, J. UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab. 9, 203-209 (2009).
    • (2009) Cell Metab. , vol.9 , pp. 203-209
    • Feldmann, H.M.1    Golozoubova, V.2    Cannon, B.3    Nedergaard, J.4
  • 62
    • 41749106457 scopus 로고    scopus 로고
    • Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality
    • Swoap, S. J. et al. vagal tone dominates autonomic control of mouse heart rate at thermoneutrality. Am. J. Physiol. Heart Circ. Physiol. 294, H1581-H1588 (2008).
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294
    • Swoap, S.J.1
  • 63
    • 0027731309 scopus 로고
    • Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
    • Lowell, B. B. et al. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue. Nature 366, 740-742 (1993).
    • (1993) Nature , vol.366 , pp. 740-742
    • Lowell, B.B.1
  • 64
    • 0015332110 scopus 로고
    • The distribution of brown adipose tissue in the human
    • Heaton, J. M. The distribution of brown adipose tissue in the human. J. Anat. 112, 35-39 (1972).
    • (1972) J. Anat. , vol.112 , pp. 35-39
    • Heaton, J.M.1
  • 65
    • 0026562272 scopus 로고
    • Analysis of uncoupling protein and its mRNA in adipose tissue deposits of adult humans
    • Garruti, G. &Ricquier, D. Analysis of uncoupling protein and its mRNA in adipose tissue deposits of adult humans. Int. J. Obes. Relat. Metab. Disord. 16, 383-390 (1992).
    • (1992) Int. J. Obes. Relat. Metab. Disord. , vol.16 , pp. 383-390
    • Garruti, G.1    Ricquier, D.2
  • 66
    • 0027456304 scopus 로고
    • Immunohistochemical detection of human brown adipose tissue uncoupling protein in an autopsy series
    • Kortelainen, M. L., Pelletier, G., Ricquier, D. &Bukowiecki, L. J. Immunohistochemical detection of human brown adipose tissue uncoupling protein in an autopsy series. J. Histochem. Cytochem. 41, 759-764 (1993).
    • (1993) J. Histochem. Cytochem. , vol.41 , pp. 759-764
    • Kortelainen, M.L.1    Pelletier, G.2    Ricquier, D.3    Bukowiecki, L.J.4
  • 67
    • 64349095231 scopus 로고    scopus 로고
    • Cold-activated brown adipose tissue in healthy men
    • Marken Lichtenbelt, w. D. et al. Cold-activated brown adipose tissue in healthy men. N. Engl. J. Med. 360, 1500-1508 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 1500-1508
    • Marken Lichtenbelt, W.D.1
  • 69
    • 64349105205 scopus 로고    scopus 로고
    • Identification and importance of brown adipose tissue in adult humans
    • Cypess, A. M. et al. Identification and importance of brown adipose tissue in adult humans. N. Engl. J. Med. 360, 1509-1517 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 1509-1517
    • Cypess, A.M.1
  • 70
    • 64349123664 scopus 로고    scopus 로고
    • Functional brown adipose tissue in healthy adults
    • virtanen, K. A. et al. Functional brown adipose tissue in healthy adults. N. Engl. J. Med. 360, 1518-1525 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 1518-1525
    • Virtanen, K.A.1
  • 71
    • 70349334680 scopus 로고    scopus 로고
    • The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue
    • Zingaretti, M. C. et al. The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue. FASEB J. 23, 3113-3120 (2009).
    • (2009) FASEB J. , vol.23 , pp. 3113-3120
    • Zingaretti, M.C.1
  • 72
    • 67650242165 scopus 로고    scopus 로고
    • High incidence of metabolically active brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
    • Saito, M. et al. High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 58, 1526-1531 (2009).
    • (2009) Diabetes , vol.58 , pp. 1526-1531
    • Saito, M.1
  • 73
    • 0030717887 scopus 로고    scopus 로고
    • Uncoupling protein gene: Quantification of expression levels in adipose tissues of obese and non-obese humans
    • Oberkofler, H. et al. Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans. J. Lipid Res. 38, 2125-2133 (1997).
    • (1997) J. Lipid Res. , vol.38 , pp. 2125-2133
    • Oberkofler, H.1
  • 74
    • 33751199972 scopus 로고    scopus 로고
    • The adipose organ of Sv129 mice contains a prevalence of brown adipocytes and shows plasticity after cold exposure
    • Murano, I., Zingaretti, C. M. &Cinti, S. The adipose organ of Sv129 mice contains a prevalence of brown adipocytes and shows plasticity after cold exposure. Adipocytes 1, 121-130 (2005).
    • (2005) Adipocytes , vol.1 , pp. 121-130
    • Murano, I.1    Zingaretti, C.M.2    Cinti, S.3
  • 75
    • 70350443275 scopus 로고    scopus 로고
    • Transdifferentiation properties of adipocytes in the adipose organ
    • Cinti, S. Transdifferentiation properties of adipocytes in the adipose organ. Am. J. Physiol. Endocrinol. Metab. 297, e977-e986 (2009).
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297
    • Cinti, S.1
  • 76
    • 0026075907 scopus 로고
    • Convertible adipose tissue in mice
    • Loncar, D. Convertible adipose tissue in mice. Cell Tissue Res. 266, 149-161 (1991).
    • (1991) Cell Tissue Res. , vol.266 , pp. 149-161
    • Loncar, D.1
  • 77
    • 0027051199 scopus 로고
    • Occurrence of brown adipocytes in rat white adipose tissue: Molecular and morphological characterization
    • Cousin, B. et al. Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. J. Cell Sci. 103, 931-942 (1992).
    • (1992) J. Cell Sci. , vol.103 , pp. 931-942
    • Cousin, B.1
  • 78
    • 50049127055 scopus 로고    scopus 로고
    • New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
    • Tseng, Y. H. et al. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature 454, 1000-1004 (2008).
    • (2008) Nature , vol.454 , pp. 1000-1004
    • Tseng, Y.H.1
  • 79
    • 34347326271 scopus 로고    scopus 로고
    • Transcriptional control of brown fat determination by PRDM16
    • Seale, P. et al. Transcriptional control of brown fat determination by PRDM16. Cell Metab. 6, 38-54 (2007).
    • (2007) Cell Metab. , vol.6 , pp. 38-54
    • Seale, P.1
  • 80
    • 33847768085 scopus 로고    scopus 로고
    • Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
    • Almind, K., Manieri, M., Sivitz, w. I., Cinti, S. &Kahn, C. R. ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice. Proc. Natl Acad. Sci. USA 104, 2366-2371 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 2366-2371
    • Almind, K.1    Manieri, M.2    Sivitz, W.I.3    Cinti, S.4    Kahn, C.R.5
  • 81
    • 55049135857 scopus 로고    scopus 로고
    • A reservoir of brown adipocyte progenitors in human skeletal muscle
    • Crisan, M. et al. A reservoir of brown adipocyte progenitors in human skeletal muscle. Stem Cells 26, 2425-2433 (2008).
    • (2008) Stem Cells , vol.26 , pp. 2425-2433
    • Crisan, M.1
  • 82
    • 50049122271 scopus 로고    scopus 로고
    • PRDM16 controls a brown fat/ skeletal muscle switch
    • Seale, P. et al. PRDM16 controls a brown fat/ skeletal muscle switch. Nature 454, 961-967 (2008).
    • (2008) Nature , vol.454 , pp. 961-967
    • Seale, P.1
  • 83
    • 34248372084 scopus 로고    scopus 로고
    • Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
    • Timmons, J. A. et al. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc Natl Acad. Sci. USA 104, 4401-4406 (2007).
    • (2007) Proc Natl Acad. Sci. USA , vol.104 , pp. 4401-4406
    • Timmons, J.A.1
  • 84
    • 33845977987 scopus 로고    scopus 로고
    • Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat
    • Xue, B. et al. Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fat. J. Lipid Res. 48, 41-51 (2007).
    • (2007) J. Lipid Res. , vol.48 , pp. 41-51
    • Xue, B.1
  • 85
    • 8444220078 scopus 로고    scopus 로고
    • Physiological uptake of [18F]fluorodeoxyglucose in the neck and upper chest region: Are there predictive characteristics?
    • Sturkenboom, M. G., Franssen, e. J., Berkhof, J. &Hoekstra, O. S. Physiological uptake of [18F]fluorodeoxyglucose in the neck and upper chest region: are there predictive characteristics? Nucl. Med. Commun. 25, 1109-1111 (2004).
    • (2004) Nucl. Med. Commun. , vol.25 , pp. 1109-1111
    • Sturkenboom, M.G.1    Franssen, E.J.2    Berkhof, J.3    Hoekstra, O.S.4
  • 86
    • 67651166870 scopus 로고    scopus 로고
    • The importance of brown adipose tissue
    • Timmons, J. A. &Pedersen, B. K. The importance of brown adipose tissue. N. Engl. J. Med. 361, 415-416 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 415-416
    • Timmons, J.A.1    Pedersen, B.K.2
  • 88
    • 67651149754 scopus 로고    scopus 로고
    • The importance of brown adipose tissue
    • Jacene, H. A. &wahl, R. L. The importance of brown adipose tissue. N. Engl. J. Med. 361, 417-418 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 417-418
    • Jacene, H.A.1    Wahl, R.L.2
  • 89
    • 67651176110 scopus 로고    scopus 로고
    • The importance of brown adipose tissue
    • Lee, P., Ho, K. K. &Fulham, M. J. The importance of brown adipose tissue. N. Engl. J. Med. 361, 418 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 418
    • Lee, P.1    Ho, K.K.2    Fulham, M.J.3
  • 90
    • 0001969684 scopus 로고
    • Fetttransplantation. Bericht uber die verhandlungen der Deutschen Gesellschaft fur Chirurgie [German]
    • Neuber, F. Fetttransplantation. Bericht uber die verhandlungen der Deutschen Gesellschaft fur Chirurgie [German]. Zentralbl. Chir. 22, 66 (1893).
    • (1893) Zentralbl. Chir. , vol.22 , pp. 66
    • Neuber, F.1
  • 91
    • 0029083965 scopus 로고
    • Long-term survival of fat transplants: Controlled demonstrations
    • Coleman, S. R. Long-term survival of fat transplants: controlled demonstrations. Aesthetic Plast. Surg. 19, 421-425 (1995).
    • (1995) Aesthetic Plast. Surg. , vol.19 , pp. 421-425
    • Coleman, S.R.1
  • 92
    • 0038088362 scopus 로고
    • The growth and development capability of transplanted fat tissue stores in rats [German]
    • Hausberger, F. X. The growth and development capability of transplanted fat tissue stores in rats [German]. Virchows Arch. Pathol. Anat. Physiol. Klin. Med. 302, 640-656 (1938).
    • (1938) Virchows Arch. Pathol. Anat. Physiol. Klin. Med. , vol.302 , pp. 640-656
    • Hausberger, F.X.1
  • 93
    • 0001656978 scopus 로고
    • Quantitative studies on the development of autotransplants of immature adipose tissue of rats
    • Hausberger, F. X. Quantitative studies on the development of autotransplants of immature adipose tissue of rats. Anat. Rec. 122, 507-515 (1955).
    • (1955) Anat. Rec. , vol.122 , pp. 507-515
    • Hausberger, F.X.1
  • 94
    • 0018662833 scopus 로고
    • Electron microscopical studies on the genesis of white adipocytes: Differentiation of immature pericytes into adipocytes in transplanted preadipose tissue
    • Iyama, K., Ohzono, K. &Usuku, G. electron microscopical studies on the genesis of white adipocytes: differentiation of immature pericytes into adipocytes in transplanted preadipose tissue. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. 31, 143-155 (1979).
    • (1979) Virchows Arch. B Cell Pathol. Incl. Mol. Pathol. , vol.31 , pp. 143-155
    • Iyama, K.1    Ohzono, K.2    Usuku, G.3
  • 95
    • 0017578251 scopus 로고
    • Adipose tissue: Contributions of nature and nurture to the obesity of an obese mutant mouse (ob/ob)
    • Ashwell, M., Meade, C. J., Medawar, P. &Sowter, C. Adipose tissue: contributions of nature and nurture to the obesity of an obese mutant mouse (ob/ob). Proc. R. Soc. Lond. B Biol. Sci. 195, 343-353 (1977).
    • (1977) Proc. R. Soc. Lond. B Biol. Sci. , vol.195 , pp. 343-353
    • Ashwell, M.1    Meade, C.J.2    Medawar, P.3    Sowter, C.4
  • 96
    • 0019445497 scopus 로고
    • Obesity: Can some fat cells enlarge while others are shrinking?
    • Ashwell, M. &Meade, C. J. Obesity: can some fat cells enlarge while others are shrinking? Lipids 16, 475-478 (1981).
    • (1981) Lipids , vol.16 , pp. 475-478
    • Ashwell, M.1    Meade, C.J.2
  • 97
    • 0021062044 scopus 로고
    • Fatty acid composition of triglycerides from adipose tissue transplanted between obese and lean mice
    • enser, M. &Ashwell, M. Fatty acid composition of triglycerides from adipose tissue transplanted between obese and lean mice. Lipids 18, 776-780 (1983).
    • (1983) Lipids , vol.18 , pp. 776-780
    • Enser, M.1    Ashwell, M.2
  • 99
    • 0346455763 scopus 로고    scopus 로고
    • Autologous fat transplants influence compensatory white adipose tissue mass increases after lipectomy
    • Lacy, e. L. &Bartness, T. J. Autologous fat transplants influence compensatory white adipose tissue mass increases after lipectomy. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R61-R70 (2004).
    • (2004) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.286
    • Lacy, E.L.1    Bartness, T.J.2
  • 100
    • 23044481097 scopus 로고    scopus 로고
    • Effects of white adipose tissue grafts on total body fat and cellularity are dependent on graft type and location
    • Lacy, e. L. &Bartness, T. J. effects of white adipose tissue grafts on total body fat and cellularity are dependent on graft type and location. Am. J. Physiol. Regul. Integr. Comp. Physiol. 289, R380-R388 (2005).
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.289
    • Lacy, E.L.1    Bartness, T.J.2
  • 101
    • 0018575815 scopus 로고
    • Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line
    • Green, H. &Kehinde, O. Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line. J. Cell. Physiol. 101, 169-171 (1979).
    • (1979) J. Cell. Physiol. , vol.101 , pp. 169-171
    • Green, H.1    Kehinde, O.2
  • 102
    • 0030982940 scopus 로고    scopus 로고
    • Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes
    • Mandrup, S., Loftus, T. M., MacDougald, O. A., Kuhajda, F. P. &Lane, M. D. Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes. Proc. Natl Acad. Sci. USA 94, 4300-4305 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 4300-4305
    • Mandrup, S.1    Loftus, T.M.2    MacDougald, O.A.3    Kuhajda, F.P.4    Lane, M.D.5
  • 103
    • 0021964298 scopus 로고
    • Characterization of ouabain-resistant mutants of the preadipocyte Ob17 clonal line. Adipose conversion in vitro and in vivo
    • Gaillard, D., Poli, P. &Negrel, R. Characterization of ouabain-resistant mutants of the preadipocyte Ob17 clonal line. Adipose conversion in vitro and in vivo. Exp. Cell Res. 156, 513-527 (1985).
    • (1985) Exp. Cell Res. , vol.156 , pp. 513-527
    • Gaillard, D.1    Poli, P.2    Negrel, R.3
  • 104
    • 0345900899 scopus 로고    scopus 로고
    • Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis
    • Fukumura, D. et al. Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis. Circ. Res. 93, e88-e97 (2003).
    • (2003) Circ. Res. , vol.93
    • Fukumura, D.1
  • 105
    • 0032723310 scopus 로고    scopus 로고
    • Reconstituted basement membrane potentiates in vivo adipogenesis of 3T3-F442A cells
    • Kawaguchi, N. et al. Reconstituted basement membrane potentiates in vivo adipogenesis of 3T3-F442A cells. Cytotechnology 31, 215-220 (1999).
    • (1999) Cytotechnology , vol.31 , pp. 215-220
    • Kawaguchi, N.1
  • 106
    • 4644222744 scopus 로고    scopus 로고
    • Generation of mature fat pads in vitro and in vivo utilizing 3-D long-term culture of 3T3-L1 preadipocytes
    • Fischbach, C. et al. Generation of mature fat pads in vitro and in vivo utilizing 3-D long-term culture of 3T3-L1 preadipocytes. Exp. Cell Res. 300, 54-64 (2004).
    • (2004) Exp. Cell Res. , vol.300 , pp. 54-64
    • Fischbach, C.1
  • 107
    • 0035988185 scopus 로고    scopus 로고
    • Alterations of insulin sensitivity by the implantation of 3T3-L1 cells in nude mice. A role for TNF-alpha?
    • Shibasaki, M. et al. Alterations of insulin sensitivity by the implantation of 3T3-L1 cells in nude mice. A role for TNF-alpha? Diabetologia 45, 518-526 (2002).
    • (2002) Diabetologia , vol.45 , pp. 518-526
    • Shibasaki, M.1
  • 108
    • 0020076459 scopus 로고
    • In vivo development of adipose tissue following implantation of lipid-depleted cultured adipocyte
    • Tavassoli, M. In vivo development of adipose tissue following implantation of lipid-depleted cultured adipocyte. Exp. Cell Res. 137, 55-62 (1982).
    • (1982) Exp. Cell Res. , vol.137 , pp. 55-62
    • Tavassoli, M.1
  • 109
    • 0020324362 scopus 로고
    • Complete differentiation in vivo of implanted cultured adipocyte precursors from adult rats
    • van, R. L. &Roncari, D. A. Complete differentiation in vivo of implanted cultured adipocyte precursors from adult rats. Cell Tissue Res. 225, 557-566 (1982).
    • (1982) Cell Tissue Res. , vol.225 , pp. 557-566
    • Van R., L.1    Roncari, D.A.2
  • 110
    • 0042839279 scopus 로고    scopus 로고
    • In vivo tracking of rat preadipocytes after autologous transplantation
    • Rieck, B. &Schlaak, S. In vivo tracking of rat preadipocytes after autologous transplantation. Ann. Plast. Surg. 51, 294-300 (2003).
    • (2003) Ann. Plast. Surg. , vol.51 , pp. 294-300
    • Rieck, B.1    Schlaak, S.2
  • 111
    • 40849100149 scopus 로고    scopus 로고
    • In vivo adipose tissue regeneration by adipose-derived stromal cells isolated from GFP transgenic mice
    • Mizuno, H. et al. In vivo adipose tissue regeneration by adipose-derived stromal cells isolated from GFP transgenic mice. Cells Tissues Organs 187, 177-185 (2008).
    • (2008) Cells Tissues Organs , vol.187 , pp. 177-185
    • Mizuno, H.1
  • 112
    • 66149125610 scopus 로고    scopus 로고
    • Preadipocyte transplantation: An in vivo study of direct leptin signaling on adipocyte morphogenesis and cell size
    • Guo, K., Mogen, J., Struzzi, S. &Zhang, Y. Preadipocyte transplantation: an in vivo study of direct leptin signaling on adipocyte morphogenesis and cell size. Am. J. Physiol. Regul. Integr. Comp. Physiol. 296, R1339-R1347 (2009).
    • (2009) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.296
    • Guo, K.1    Mogen, J.2    Struzzi, S.3    Zhang, Y.4
  • 113
    • 3843146095 scopus 로고    scopus 로고
    • A novel preadipocyte cell line established from mouse adult mature adipocytes
    • Yagi, K., Kondo, D., Okazaki, Y. &Kano, K. A novel preadipocyte cell line established from mouse adult mature adipocytes. Biochem. Biophys. Res. Commun. 321, 967-974 (2004).
    • (2004) Biochem. Biophys. Res. Commun. , vol.321 , pp. 967-974
    • Yagi, K.1    Kondo, D.2    Okazaki, Y.3    Kano, K.4
  • 114
    • 0038657944 scopus 로고    scopus 로고
    • Measurement in vivo of the survival rate in autologous adipocyte transplantation
    • Rieck, B. &Schlaak, S. Measurement in vivo of the survival rate in autologous adipocyte transplantation. Plast. Reconstr. Surg. 111, 2315-2323 (2003).
    • (2003) Plast. Reconstr. Surg. , vol.111 , pp. 2315-2323
    • Rieck, B.1    Schlaak, S.2
  • 115
    • 0027081550 scopus 로고
    • Brown adipose tissue: Magnetic resonance imaging and ultrastructural studies after transplantation in syngeneic rats
    • Dellagiacoma, G. et al. Brown adipose tissue: magnetic resonance imaging and ultrastructural studies after transplantation in syngeneic rats. Transplant. Proc. 24, 2986 (1992).
    • (1992) Transplant. Proc. , vol.24 , pp. 2986
    • Dellagiacoma, G.1
  • 116
    • 0024600201 scopus 로고
    • Experimental implantation of adipose tissue fragments
    • Smahel, J. experimental implantation of adipose tissue fragments. Br. J. Plast. Surg. 42, 207-211 (1989).
    • (1989) Br. J. Plast. Surg. , vol.42 , pp. 207-211
    • Smahel, J.1
  • 117
    • 0021076038 scopus 로고
    • Development of interscapular brown adipose tissue in the hamster. II - Differentiation of transplants in the anterior chamber of the eye: Role of the sympathetic innervation
    • Nechad, M. &Olson, L. Development of interscapular brown adipose tissue in the hamster. II - Differentiation of transplants in the anterior chamber of the eye: role of the sympathetic innervation. Biol. Cell 48, 167-174 (1983).
    • (1983) Biol. Cell , vol.48 , pp. 167-174
    • Nechad, M.1    Olson, L.2
  • 118
    • 0013883433 scopus 로고
    • Morphological differentiation of implanted brown and white fats
    • Ferren, L. Morphological differentiation of implanted brown and white fats. Trans. Kans. Acad. Sci. 69, 350-353 (1966).
    • (1966) Trans. Kans. Acad. Sci. , vol.69 , pp. 350-353
    • Ferren, L.1
  • 119
    • 0022972074 scopus 로고
    • Brown adipose tissue: Contributions of nature and nurture to the obesity of an obese mutant mouse (ob/ob)
    • Ashwell, M., wells, C. &Dunnett, S. B. Brown adipose tissue: contributions of nature and nurture to the obesity of an obese mutant mouse (ob/ob). Int. J. Obes. 10, 355-373 (1986).
    • (1986) Int. J. Obes. , vol.10 , pp. 355-373
    • Ashwell, M.1    Wells, C.2    Dunnett, S.B.3
  • 120
    • 0022578158 scopus 로고
    • Adipose tissue triacylglycerol fatty acids of obese and lean mice: In situ and in transplants
    • Roberts, J. L., Ashwell, M. &enser, M. Brown adipose tissue triacylglycerol fatty acids of obese and lean mice: in situ and in transplants. Lipids 21, 195-201 (1986).
    • (1986) Lipids , vol.21 , pp. 195-201
    • Roberts, J.L.1    Ashwell, M.2    Brown, E.M.3
  • 121
    • 67349228443 scopus 로고    scopus 로고
    • Lipodystrophies: Disorders of adipose tissue biology
    • Garg, A. &Agarwal, A. K. Lipodystrophies: disorders of adipose tissue biology. Biochim. Biophys. Acta 1791, 507-513 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 507-513
    • Garg, A.1    Agarwal, A.K.2
  • 122
    • 0033965557 scopus 로고    scopus 로고
    • Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice
    • Gavrilova, O. et al. Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. J. Clin. Invest. 105, 271-278 (2000).
    • (2000) J. Clin. Invest. , vol.105 , pp. 271-278
    • Gavrilova, O.1
  • 123
    • 0034708580 scopus 로고    scopus 로고
    • Mechanism of insulin resistance in A-ZIP/F-1 fatless mice
    • Kim, J. K. et al. Mechanism of insulin resistance in A-ZIP/F-1 fatless mice. J. Biol. Chem. 275, 8456-8460 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 8456-8460
    • Kim, J.K.1
  • 124
    • 0036724616 scopus 로고    scopus 로고
    • Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy
    • Colombo, C. et al. Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy. Diabetes 51, 2727-2733 (2002).
    • (2002) Diabetes , vol.51 , pp. 2727-2733
    • Colombo, C.1
  • 125
    • 0037148928 scopus 로고    scopus 로고
    • Leptin-replacement therapy for lipodystrophy
    • Oral, e. A. et al. Leptin-replacement therapy for lipodystrophy. N. Engl. J. Med. 346, 570-578 (2002).
    • (2002) N. Engl. J. Med. , vol.346 , pp. 570-578
    • Oral, E.A.1
  • 126
    • 0031965266 scopus 로고    scopus 로고
    • Leptin regulates proinflammatory immune responses
    • Loffreda, S. et al. Leptin regulates proinflammatory immune responses. FASEB J. 12, 57-65 (1998).
    • (1998) FASEB J. , vol.12 , pp. 57-65
    • Loffreda, S.1
  • 127
    • 0035816639 scopus 로고    scopus 로고
    • Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
    • Yamagishi, S. I. et al. Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. J. Biol. Chem. 276, 25096-25100 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 25096-25100
    • Yamagishi, S.I.1
  • 128
    • 0038481184 scopus 로고    scopus 로고
    • Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:Diacylglycerol acyltransferase 1
    • Chen, H. C., Jensen, D. R., Myers, H. M., eckel, R. H. &Farese, R. v. Jr. Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase 1. J. Clin. Invest. 111, 1715-1722 (2003).
    • (2003) J. Clin. Invest. , vol.111 , pp. 1715-1722
    • Chen, H.C.1    Jensen, D.R.2    Myers, H.M.3    Eckel, R.H.4    Farese Jr. R., V.5
  • 129
    • 22544449911 scopus 로고    scopus 로고
    • Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility
    • Klebanov, S., Astle, C. M., DeSimone, O., Ablamunits, v. &Harrison, D. e. Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility. J. Endocrinol. 186, 203-211 (2005).
    • (2005) J. Endocrinol. , vol.186 , pp. 203-211
    • Klebanov, S.1    Astle, C.M.2    Desimone, O.3    Ablamunits, V.4    Harrison, D.E.5
  • 130
    • 34047130209 scopus 로고    scopus 로고
    • Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice
    • Sennello, J. A., Fayad, R., Pini, M., Gove, M. e. &Fantuzzi, G. Transplantation of wild-type white adipose tissue normalizes metabolic, immune and inflammatory alterations in leptin-deficient ob/ob mice. Cytokine 36, 261-266 (2006).
    • (2006) Cytokine , vol.36 , pp. 261-266
    • Sennello, J.A.1    Fayad, R.2    Pini, M.3    Gove, M.E.4    Fantuzzi, G.5
  • 131
    • 33845979159 scopus 로고    scopus 로고
    • Combined leptin actions on adipose tissue and hypothalamus are required to deplete adipocyte fat in lean rats: Implications for obesity treatment
    • Park, B. H. et al. Combined leptin actions on adipose tissue and hypothalamus are required to deplete adipocyte fat in lean rats: implications for obesity treatment. J. Biol. Chem. 281, 40283-40291 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 40283-40291
    • Park, B.H.1
  • 132
    • 33847637510 scopus 로고    scopus 로고
    • Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue
    • Konrad, D., Rudich, A. &Schoenle, e. J. Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue. Diabetologia 50, 833-839 (2007).
    • (2007) Diabetologia , vol.50 , pp. 833-839
    • Konrad, D.1    Rudich, A.2    Schoenle, E.J.3
  • 133
    • 0014950773 scopus 로고
    • Insulin responsiveness and lipid synthesis in human fat cells of different sizes: Effect of the incubation medium
    • Smith, U. Insulin responsiveness and lipid synthesis in human fat cells of different sizes: effect of the incubation medium. Biochim. Biophys. Acta 218, 417-423 (1970).
    • (1970) Biochim. Biophys. Acta , vol.218 , pp. 417-423
    • Smith, U.1
  • 134
    • 42649144463 scopus 로고    scopus 로고
    • Beneficial effects of subcutaneous fat transplantation on metabolism
    • Tran, T. T., Yamamoto, Y., Gesta, S. &Kahn, C. R. Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab. 7, 410-420 (2008).
    • (2008) Cell Metab. , vol.7 , pp. 410-420
    • Tran, T.T.1    Yamamoto, Y.2    Gesta, S.3    Kahn, C.R.4
  • 135
    • 41849094743 scopus 로고    scopus 로고
    • Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment
    • Hocking, S. L., Chisholm, D. J. &James, D. e. Studies of regional adipose transplantation reveal a unique and beneficial interaction between subcutaneous adipose tissue and the intra-abdominal compartment. Diabetologia 51, 900-902 (2008).
    • (2008) Diabetologia , vol.51 , pp. 900-902
    • Hocking, S.L.1    Chisholm, D.J.2    James, D.E.3
  • 136
    • 70649109834 scopus 로고    scopus 로고
    • Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism
    • Schulz, T. J. &Tseng, Y. H. emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism. Cytokine Growth Factor Rev. 20, 523-531 (2009).
    • (2009) Cytokine Growth Factor Rev. , vol.20 , pp. 523-531
    • Schulz, T.J.1    Tseng, Y.H.2
  • 137
    • 69349088117 scopus 로고    scopus 로고
    • Initiation of myoblast to brown fat switch by a PRDM16-C/eBP-beta transcriptional complex
    • Kajimura, S. et al. Initiation of myoblast to brown fat switch by a PRDM16-C/eBP-beta transcriptional complex. Nature 460, 1154-1158 (2009).
    • (2009) Nature , vol.460 , pp. 1154-1158
    • Kajimura, S.1
  • 138
    • 18744373595 scopus 로고    scopus 로고
    • Human adipose tissue is a source of multipotent stem cells
    • Zuk, P. A. et al. Human adipose tissue is a source of multipotent stem cells. Mol. Biol. Cell 13, 4279-4295 (2002).
    • (2002) Mol. Biol. Cell , vol.13 , pp. 4279-4295
    • Zuk, P.A.1
  • 139
    • 34248332602 scopus 로고    scopus 로고
    • Adiposederived stem cells for regenerative medicine
    • Gimble, J. M., Katz, A. J. &Bunnell, B. A. Adiposederived stem cells for regenerative medicine. Circ. Res. 100, 1249-1260 (2007).
    • (2007) Circ. Res. , vol.100 , pp. 1249-1260
    • Gimble, J.M.1    Katz, A.J.2    Bunnell, B.A.3
  • 140
    • 34147107634 scopus 로고    scopus 로고
    • Concise review: Adipose tissue-derived stromal cells--basic and clinical implications for novel cell-based therapies
    • Schaffler, A. &Buchler, C. Concise review: adipose tissue-derived stromal cells--basic and clinical implications for novel cell-based therapies. Stem Cells 25, 818-827 (2007).
    • (2007) Stem Cells , vol.25 , pp. 818-827
    • Schaffler, A.1    Buchler, C.2
  • 141
    • 10744222119 scopus 로고    scopus 로고
    • Plasticity of human adipose lineage cells toward endothelial cells: Physiological and therapeutic perspectives
    • Planat-Benard, v. et al. Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives. Circulation 109, 656-663 (2004).
    • (2004) Circulation , vol.109 , pp. 656-663
    • Planat-Benard, V.1
  • 142
    • 53549130485 scopus 로고    scopus 로고
    • White fat progenitor cells reside in the adipose vasculature
    • Tang, w. et al. white fat progenitor cells reside in the adipose vasculature. Science 322, 583-586 (2008).
    • (2008) Science , vol.322 , pp. 583-586
    • Tang, W.1
  • 143
    • 53549134683 scopus 로고    scopus 로고
    • Identification of white adipocyte progenitor cells in vivo
    • Rodeheffer, M. S., Birsoy, K. &Friedman, J. M. Identification of white adipocyte progenitor cells in vivo. Cell 135, 240-249 (2008).
    • (2008) Cell , vol.135 , pp. 240-249
    • Rodeheffer, M.S.1    Birsoy, K.2    Friedman, J.M.3
  • 144
    • 70350228797 scopus 로고    scopus 로고
    • Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat diet
    • Joe, A. w., Yi, L., even, Y., vogl, A. w. &Rossi, F. M. Depot-specific differences in adipogenic progenitor abundance and proliferative response to high-fat diet. Stem Cells 27, 2563-2570 (2009).
    • (2009) Stem Cells , vol.27 , pp. 2563-2570
    • Joe, A.W.1    Yi, L.2    Even, Y.3    Vogl, A.W.4    Rossi, F.M.5
  • 145
    • 33751168064 scopus 로고    scopus 로고
    • Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue
    • Izadpanah, R. et al. Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue. J. Cell Biochem. 99, 1285-1297 (2006).
    • (2006) J. Cell Biochem. , vol.99 , pp. 1285-1297
    • Izadpanah, R.1
  • 146
    • 35848934162 scopus 로고    scopus 로고
    • Direct comparison of human mesenchymal stem cells derived from adipose tissues and bone marrow in mediating neovascularization in response to vascular ischemia
    • Kim, Y. et al. Direct comparison of human mesenchymal stem cells derived from adipose tissues and bone marrow in mediating neovascularization in response to vascular ischemia. Cell Physiol. Biochem. 20, 867-876 (2007).
    • (2007) Cell Physiol. Biochem. , vol.20 , pp. 867-876
    • Kim, Y.1
  • 147
    • 34548442823 scopus 로고    scopus 로고
    • Comparison of mesenchymal stem cells from different tissues to suppress T-cell activation
    • Keyser, K. A., Beagles, K. e. &Kiem, H. P. Comparison of mesenchymal stem cells from different tissues to suppress T-cell activation. Cell Transplant. 16, 555-562 (2007).
    • (2007) Cell Transplant. , vol.16 , pp. 555-562
    • Keyser, K.A.1    Beagles, K.E.2    Kiem, H.P.3
  • 148
    • 40949099450 scopus 로고    scopus 로고
    • Cell specific differences between human adipose-derived and mesenchymalstromal cells despite similar differentiation potentials
    • Noel, D. et al. Cell specific differences between human adipose-derived and mesenchymalstromal cells despite similar differentiation potentials. Exp. Cell Res. 314, 1575-1584 (2008).
    • (2008) Exp. Cell Res. , vol.314 , pp. 1575-1584
    • Noel, D.1
  • 149
    • 33744929131 scopus 로고    scopus 로고
    • Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates
    • Yoshimura, K. et al. Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. J. Cell Physiol. 208, 64-76 (2006).
    • (2006) J. Cell Physiol. , vol.208 , pp. 64-76
    • Yoshimura, K.1
  • 150
    • 37849018186 scopus 로고    scopus 로고
    • Cell-assisted lipotransfer for cosmetic breast augmentation: Supportive use of adipose-derived stem/stromal cells
    • Yoshimura, K. et al. Cell-assisted lipotransfer for cosmetic breast augmentation: supportive use of adipose-derived stem/stromal cells. Aesthetic Plast. Surg. 32, 48-55 (2008).
    • (2008) Aesthetic Plast. Surg. , vol.32 , pp. 48-55
    • Yoshimura, K.1
  • 151
    • 64049104052 scopus 로고    scopus 로고
    • Expanded adipose-derived stem cells for the treatment of complex perianal fistula: A phase II clinical trial
    • Garcia-Olmo, D. et al. expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial. Dis. Colon Rectum 52, 79-86 (2009).
    • (2009) Dis. Colon Rectum , vol.52 , pp. 79-86
    • Garcia-Olmo, D.1
  • 152
    • 73949123818 scopus 로고    scopus 로고
    • Adipose tissue-derived stem cells: Characterization and potential for cardiovascular repair
    • Madonna, R., Geng, Y. J. &De Caterina, R. Adipose tissue-derived stem cells: characterization and potential for cardiovascular repair. Arterioscler. Thromb. Vasc. Biol. 29, 1723-1729 (2009).
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 1723-1729
    • Madonna, R.1    Geng, Y.J.2    De Caterina, R.3
  • 153
    • 70349739571 scopus 로고    scopus 로고
    • Dedifferentiated fat cells convert to cardiomyocyte phenotype and repair infarcted cardiac tissue in rats
    • Jumabay, M. et al. Dedifferentiated fat cells convert to cardiomyocyte phenotype and repair infarcted cardiac tissue in rats. J. Mol. Cell. Cardiol. 47, 565-575 (2009).
    • (2009) J. Mol. Cell. Cardiol. , vol.47 , pp. 565-575
    • Jumabay, M.1
  • 155
    • 70349580508 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Innovative therapeutic tools for rheumatic diseases
    • Djouad, F., Bouffi, C., Ghannam, S., Noel, D. &Jorgensen, C. Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat. Rev. Rheumatol. 5, 392-399 (2009).
    • (2009) Nat. Rev. Rheumatol. , vol.5 , pp. 392-399
    • Djouad, F.1    Bouffi, C.2    Ghannam, S.3    Noel, D.4    Jorgensen, C.5
  • 156
    • 20244381685 scopus 로고    scopus 로고
    • Immunomodulatory effect of human adipose tissue-derived adult stem cells: Comparison with bone marrow mesenchymal stem cells
    • Puissant, B. et al. Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparison with bone marrow mesenchymal stem cells. Br. J. Haematol. 129, 118-129 (2005).
    • (2005) Br. J. Haematol. , vol.129 , pp. 118-129
    • Puissant, B.1
  • 157
    • 33750559121 scopus 로고    scopus 로고
    • Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease
    • Yanez, R. et al. Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease. Stem Cells 24, 2582-2591 (2006).
    • (2006) Stem Cells , vol.24 , pp. 2582-2591
    • Yanez, R.1
  • 158
    • 60449093316 scopus 로고    scopus 로고
    • Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
    • Gonzalez-Rey, e. et al. Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis. Gut 58, 929-939 (2009).
    • (2009) Gut , vol.58 , pp. 929-939
    • Gonzalez-Rey, E.1
  • 159
    • 73349117464 scopus 로고    scopus 로고
    • MiR-21 regulates adipogenic differentiation through the modulation of tgf-beta signaling in mesenchymal stem cells derived from human adipose tissue
    • Kim, Y. J., Hwang, S. J., Bae, Y. C. &Jung, J. S. miR-21 regulates adipogenic differentiation through the modulation of tgf-beta signaling in mesenchymal stem cells derived from human adipose tissue. Stem Cells 27, 3093-3102 (2009).
    • (2009) Stem Cells , vol.27 , pp. 3093-3102
    • Kim, Y.J.1    Hwang, S.J.2    Bae, Y.C.3    Jung, J.S.4
  • 160
    • 0030642286 scopus 로고    scopus 로고
    • Obese (ob) gene defects are rare in human obesity
    • Carlsson, B. et al. Obese (ob) gene defects are rare in human obesity. Obes. Res. 5, 30-35 (1997).
    • (1997) Obes. Res. , vol.5 , pp. 30-35
    • Carlsson, B.1
  • 161
    • 0032747280 scopus 로고    scopus 로고
    • Recombinant leptin for weight loss in obese and lean adults: A randomized, controlled, dose-escalation trial
    • Heymsfield, S. B. et al. Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial. JAMA 282, 1568-1575 (1999).
    • (1999) JAMA , vol.282 , pp. 1568-1575
    • Heymsfield, S.B.1
  • 162
    • 0022536596 scopus 로고
    • Uptake of glucose and release of fatty acids and glycerol by rat brown adipose tissue in vivo
    • Ma, S. w. &Foster, D. O. Uptake of glucose and release of fatty acids and glycerol by rat brown adipose tissue in vivo. Can. J. Physiol. Pharmacol. 64, 609-614 (1986).
    • (1986) Can. J. Physiol. Pharmacol. , vol.64 , pp. 609-614
    • Ma, S.W.1    Foster, D.O.2
  • 163
    • 46149086585 scopus 로고    scopus 로고
    • Central control of thermogenesis in mammals
    • Morrison, S. F., Nakamura, K. &Madden, C. J. Central control of thermogenesis in mammals. Exp. Physiol. 93, 773-797 (2008).
    • (2008) Exp. Physiol. , vol.93 , pp. 773-797
    • Morrison, S.F.1    Nakamura, K.2    Madden, C.J.3
  • 164
    • 0023277544 scopus 로고
    • Glucose metabolism in isolated brown adipocytes under beta-adrenergic stimulation. Quantitative contribution of glucose to total thermogenesis
    • Isler, D., Hill, H. P. &Meier, M. K. Glucose metabolism in isolated brown adipocytes under beta-adrenergic stimulation. Quantitative contribution of glucose to total thermogenesis. Biochem. J. 245, 789-793 (1987).
    • (1987) Biochem. J. , vol.245 , pp. 789-793
    • Isler, D.1    Hill, H.P.2    Meier, M.K.3
  • 166
    • 0020693920 scopus 로고
    • Luxuskonsumption, diet-induced thermogenesis and brown fat: The case in favour
    • Rothwell, N. J. &Stock, M. J. Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. Clin. Sci. 64, 19-23 (1983).
    • (1983) Clin. Sci. , vol.64 , pp. 19-23
    • Rothwell, N.J.1    Stock, M.J.2
  • 167
    • 18244386043 scopus 로고    scopus 로고
    • Expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo
    • Rossmeisl, M. et al. expression of the uncoupling protein 1 from the aP2 gene promoter stimulates mitochondrial biogenesis in unilocular adipocytes in vivo. Eur. J. Biochem. 269, 19-28 (2002).
    • (2002) Eur. J. Biochem. , vol.269 , pp. 19-28
    • Rossmeisl, M.1
  • 168
    • 0030754240 scopus 로고    scopus 로고
    • Preadipocyte function and aging: Links between age-related changes in cell dynamics and altered fat tissue function
    • Kirkland, J. L. &Dobson, D. e. Preadipocyte function and aging: links between age-related changes in cell dynamics and altered fat tissue function. J. Am. Geriatr. Soc. 45, 959-967 (1997).
    • (1997) J. Am. Geriatr. Soc. , vol.45 , pp. 959-967
    • Kirkland, J.L.1    Dobson, D.E.2
  • 169
    • 0034972714 scopus 로고    scopus 로고
    • Altered expression of C/eBP family members results in decreased adipogenesis with aging
    • Karagiannides, I. et al. Altered expression of C/eBP family members results in decreased adipogenesis with aging. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280, R1772-R1780 (2001).
    • (2001) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.280
    • Karagiannides, I.1
  • 170
    • 42549164595 scopus 로고    scopus 로고
    • Regional anatomic and age effects on cell function of human adipose-derived stem cells
    • Schipper, B. M., Marra, K. G., Zhang, w., Donnenberg, A. D. &Rubin, J. P. Regional anatomic and age effects on cell function of human adipose-derived stem cells. Ann. Plast. Surg. 60, 538-544 (2008).
    • (2008) Ann. Plast. Surg. , vol.60 , pp. 538-544
    • Schipper, B.M.1    Marra, K.G.2    Zhang, W.3    Donnenberg, A.D.4    Rubin, J.P.5
  • 171
    • 17144363265 scopus 로고    scopus 로고
    • Spontaneous human adult stem cell transformation
    • Rubio, D. et al. Spontaneous human adult stem cell transformation. Cancer Res. 65, 3035-3039 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 3035-3039
    • Rubio, D.1
  • 172
    • 77950188754 scopus 로고    scopus 로고
    • Induction of uncoupling protein-1 in mouse embryonic fibroblast-derived adipocytes by retinoic acid
    • doi:10.1038/oby.2009.330.
    • Mercader, J., Palou, A. &Luisa, B. M. Induction of uncoupling protein-1 in mouse embryonic fibroblast-derived adipocytes by retinoic acid. Obesity doi:10.1038/oby.2009.330.
    • Obesity
    • Mercader, J.1    Palou, A.2    Luisa, B.M.3
  • 173
    • 48549087683 scopus 로고    scopus 로고
    • Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis
    • Scheideler, M. et al. Comparative transcriptomics of human multipotent stem cells during adipogenesis and osteoblastogenesis. BMC Genomics 9, 340 (2008).
    • (2008) BMC Genomics , vol.9 , pp. 340
    • Scheideler, M.1
  • 174
    • 57749113504 scopus 로고    scopus 로고
    • Homing properties of adiposederived stem cells to intracerebral glioma and the effects of adenovirus infection
    • Lamfers, M. et al. Homing properties of adiposederived stem cells to intracerebral glioma and the effects of adenovirus infection. Cancer Lett. 274, 78-87 (2009).
    • (2009) Cancer Lett. , vol.274 , pp. 78-87
    • Lamfers, M.1
  • 175
    • 44249105593 scopus 로고    scopus 로고
    • Microbubbles in ultrasound-triggered drug and gene delivery
    • Hernot, S. &Klibanov, A. L. Microbubbles in ultrasound-triggered drug and gene delivery. Adv. Drug Deliv. Rev. 60, 1153-1166 (2008).
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1153-1166
    • Hernot, S.1    Klibanov, A.L.2
  • 176
    • 57349146702 scopus 로고    scopus 로고
    • Nonviral delivery of siRNA into mesenchymal stem cells by a combination of ultrasound and microbubbles
    • Otani, K. et al. Nonviral delivery of siRNA into mesenchymal stem cells by a combination of ultrasound and microbubbles. J. Control Release 133, 146-153 (2009).
    • (2009) J. Control Release , vol.133 , pp. 146-153
    • Otani, K.1
  • 177
    • 62249191413 scopus 로고    scopus 로고
    • Stem cell-mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury
    • Lee, S. w. et al. Stem cell-mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury. J. Orthop. Res. 27, 295-302 (2009).
    • (2009) J. Orthop. Res. , vol.27 , pp. 295-302
    • Lee, S.W.1
  • 178
    • 78951494233 scopus 로고    scopus 로고
    • Homing of adipose-derived stem cells to radiofrequency catheter ablated canine atrium and differentiation into cardiomyocyte-like cells
    • doi:10.1016/j.ijcard.2009.07.016.
    • Kim, U. et al. Homing of adipose-derived stem cells to radiofrequency catheter ablated canine atrium and differentiation into cardiomyocyte-like cells. Int. J. Cardiol. doi:10.1016/j.ijcard.2009.07.016.
    • Int. J. Cardiol.
    • Kim, U.1
  • 179
    • 64849112516 scopus 로고    scopus 로고
    • Adipose tissue-derived cells improve cardiac function following myocardial infarction
    • Schenke-Layland, K. et al. Adipose tissue-derived cells improve cardiac function following myocardial infarction. J. Surg. Res. 153, 217-223 (2009).
    • (2009) J. Surg. Res. , vol.153 , pp. 217-223
    • Schenke-Layland, K.1
  • 180
    • 70350211437 scopus 로고    scopus 로고
    • Thermosensitive injectable hyaluronic acid hydrogel for adipose tissue engineering
    • Tan, H. et al. Thermosensitive injectable hyaluronic acid hydrogel for adipose tissue engineering. Biomaterials 30, 6844-6853 (2009).
    • (2009) Biomaterials , vol.30 , pp. 6844-6853
    • Tan, H.1
  • 181
    • 20444402992 scopus 로고    scopus 로고
    • Adipose tissue engineering using mesenchymal stem cells attached to injectable PLGA spheres
    • Choi, Y. S., Park, S. N. &Suh, H. Adipose tissue engineering using mesenchymal stem cells attached to injectable PLGA spheres. Biomaterials 26, 5855-5863 (2005).
    • (2005) Biomaterials , vol.26 , pp. 5855-5863
    • Choi, Y.S.1    Park, S.N.2    Suh, H.3
  • 182
    • 77950023222 scopus 로고    scopus 로고
    • Comparison of readily available scaffolds for adipose tissue engineering using adiposederived stem cells
    • doi:10.1016/j.bjps.2009.01.069.
    • Itoi, Y., Takatori, M., Hyakusoku, H. &Mizuno, H. Comparison of readily available scaffolds for adipose tissue engineering using adiposederived stem cells. J. Plast. Reconstr. Aesthet. Surg. doi:10.1016/j.bjps.2009.01.069.
    • J. Plast. Reconstr. Aesthet. Surg.
    • Itoi, Y.1    Takatori, M.2    Hyakusoku, H.3    Mizuno, H.4
  • 183
    • 12144287799 scopus 로고    scopus 로고
    • Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells
    • Rehman, J. et al. Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells. Circulation 109, 1292-1298 (2004).
    • (2004) Circulation , vol.109 , pp. 1292-1298
    • Rehman, J.1
  • 184
    • 33846877870 scopus 로고    scopus 로고
    • VeGF gene therapy for the survival of transplanted fat tissue in nude mice
    • Yi, C. G. et al. veGF gene therapy for the survival of transplanted fat tissue in nude mice. J. Plast. Reconstr. Aesthet. Surg. 60, 272-278 (2007).
    • (2007) J. Plast. Reconstr. Aesthet. Surg. , vol.60 , pp. 272-278
    • Yi, C.G.1
  • 185
    • 58949086464 scopus 로고    scopus 로고
    • Transplantation of adiposederived stem cells overexpressing hHGF into cardiac tissue
    • Zhu, X. Y. et al. Transplantation of adiposederived stem cells overexpressing hHGF into cardiac tissue. Biochem. Biophys. Res. Commun. 379, 1084-1090 (2009).
    • (2009) Biochem. Biophys. Res. Commun. , vol.379 , pp. 1084-1090
    • Zhu, X.Y.1
  • 186
    • 69249149297 scopus 로고    scopus 로고
    • Locally delivered growth factor enhances the angiogenic efficacy of adipose-derived stromal cells transplanted to ischemic limbs
    • Bhang, S. H. et al. Locally delivered growth factor enhances the angiogenic efficacy of adipose-derived stromal cells transplanted to ischemic limbs. Stem Cells 27, 1976-1986 (2009).
    • (2009) Stem Cells , vol.27 , pp. 1976-1986
    • Bhang, S.H.1
  • 187
    • 58349089705 scopus 로고    scopus 로고
    • Effect of local, long-term delivery of platelet-derived growth factor (PDGF) on injected fat graft survival in severe combined immunodeficient (SCID) mice
    • Craft, R. O. et al. effect of local, long-term delivery of platelet-derived growth factor (PDGF) on injected fat graft survival in severe combined immunodeficient (SCID) mice. J. Plast. Reconstr. Aesthet. Surg. 62, 235-243 (2009).
    • (2009) J. Plast. Reconstr. Aesthet. Surg. , vol.62 , pp. 235-243
    • Craft, R.O.1
  • 188
    • 20044370822 scopus 로고    scopus 로고
    • The effect of interleukin-8 on the viability of injected adipose tissue in nude mice
    • Shoshani, O. et al. The effect of interleukin-8 on the viability of injected adipose tissue in nude mice. Plast. Reconstr. Surg. 115, 853-859 (2005).
    • (2005) Plast. Reconstr. Surg. , vol.115 , pp. 853-859
    • Shoshani, O.1
  • 189
    • 52149094789 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 improves the transplanted adipocyte survival in mice
    • Kuramochi, D. et al. Matrix metalloproteinase 2 improves the transplanted adipocyte survival in mice. Eur. J. Clin. Invest. 38, 752-759 (2008).
    • (2008) Eur. J. Clin. Invest. , vol.38 , pp. 752-759
    • Kuramochi, D.1
  • 190
    • 0026722013 scopus 로고
    • The effect of preoperative needle abrasion of the recipient site on survival of autologous free fat grafts in rats
    • Samdal, F., Skolleborg, K. C. &Berthelsen, B. The effect of preoperative needle abrasion of the recipient site on survival of autologous free fat grafts in rats. Scand. J. Plast. Reconstr. Surg. Hand Surg. 26, 33-36 (1992).
    • (1992) Scand. J. Plast. Reconstr. Surg. Hand Surg. , vol.26 , pp. 33-36
    • Samdal, F.1    Skolleborg, K.C.2    Berthelsen, B.3
  • 191
    • 70350434580 scopus 로고    scopus 로고
    • Human multipotent adiposederived stem cells differentiate into functional brown adipocytes
    • elabd, C. et al. Human multipotent adiposederived stem cells differentiate into functional brown adipocytes. Stem Cells 27, 2753-2760 (2009).
    • (2009) Stem Cells , vol.27 , pp. 2753-2760
    • Elabd, C.1
  • 192
    • 41149106402 scopus 로고    scopus 로고
    • The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: First randomized placebo-controlled study of myoblast transplantation
    • Menasche, P. et al. The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation. Circulation 117, 1189-1200 (2008).
    • (2008) Circulation , vol.117 , pp. 1189-1200
    • Menasche, P.1
  • 193
    • 67649993062 scopus 로고    scopus 로고
    • The BALANCe Study: Clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction
    • Yousef, M. et al. The BALANCe Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction. J. Am. Coll. Cardiol. 53, 2262-2269 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.53 , pp. 2262-2269
    • Yousef, M.1
  • 194
    • 71849111732 scopus 로고    scopus 로고
    • Long term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction. The ASTAMI randomized, controlled study
    • Beitnes, J. O. et al. Long term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction. The ASTAMI randomized, controlled study. Heart 95, 1983-1989 (2009).
    • (2009) Heart , vol.95 , pp. 1983-1989
    • Beitnes, J.O.1
  • 195
    • 33645743539 scopus 로고    scopus 로고
    • Intracoronary bone marrow cell transfer after myocardial infarction: Eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial
    • Meyer, G. P. et al. Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 113, 1287-1294 (2006).
    • (2006) Circulation , vol.113 , pp. 1287-1294
    • Meyer, G.P.1
  • 196
    • 45849112916 scopus 로고    scopus 로고
    • Adipose-derived stem cells: Isolation, expansion and differentiation
    • Bunnell, B. A., Flaat, M., Gagliardi, C., Patel, B. &Ripoll, C. Adipose-derived stem cells: isolation, expansion and differentiation. Methods 45, 115-120 (2008).
    • (2008) Methods , vol.45 , pp. 115-120
    • Bunnell, B.A.1    Flaat, M.2    Gagliardi, C.3    Patel, B.4    Ripoll, C.5
  • 197
    • 76749170645 scopus 로고    scopus 로고
    • Utility of transplantation in studying adipocyte biogenesis and function
    • doi:10.1016/j.mce.2009.08.022.
    • Zhang, Y. Utility of transplantation in studying adipocyte biogenesis and function. Mol. Cell. Endocrinol. doi:10.1016/j.mce.2009.08.022.
    • Mol. Cell. Endocrinol.
    • Zhang, Y.1


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