메뉴 건너뛰기




Volumn 1190, Issue , 2010, Pages 86-96

Ellagic acid and polyphenolics present in walnut kernels inhibit in vitro human peripheral blood mononuclear cell proliferation and alter cytokine production

Author keywords

Ellagic acid; Juglans regia; Nut allergy; Polyphenolics; Walnut

Indexed keywords

CYTOKINE; ELLAGIC ACID; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHYTOHEMAGGLUTININ; POLYPHENOL DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA;

EID: 77950203508     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.05259.x     Document Type: Conference Paper
Times cited : (34)

References (69)
  • 1
    • 0026654541 scopus 로고
    • A possible protective effect of nut consumption on risk of coronary heart disease. the Adventist Health Study
    • Fraser, G.E. et al. 1992. A possible protective effect of nut consumption on risk of coronary heart disease. The Adventist Health Study. Arch. Intern. Med. 152: 1416-1424.
    • (1992) Arch. Intern. Med. , vol.152 , pp. 1416-1424
    • Fraser, G.E.1
  • 2
    • 0032517536 scopus 로고    scopus 로고
    • Frequent nut consumption and risk of coronary heart disease in women: Prospective cohort study
    • Hu, F.B. et al. 1998. Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study. Brit. Med. J. 317: 1341-1345.
    • (1998) Brit. Med. J. , vol.317 , pp. 1341-1345
    • Hu, F.B.1
  • 3
    • 0032839428 scopus 로고    scopus 로고
    • Nut consumption, vegetarian diets, ischemic heart disease risk, and all-cause mortality: Evidence from epidemiologic studies
    • Sabate, J. 1999. Nut consumption, vegetarian diets, ischemic heart disease risk, and all-cause mortality: evidence from epidemiologic studies. Am. J. Clin. Nutr. 70: 500S-503S.
    • (1999) Am. J. Clin. Nutr. , vol.70
    • Sabate, J.1
  • 4
    • 0028259008 scopus 로고
    • Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol
    • Abbey, M. et al. 1994. Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol. Am. J. Clin. Nutr. 59: 995-999.
    • (1994) Am. J. Clin. Nutr. , vol.59 , pp. 995-999
    • Abbey, M.1
  • 5
    • 0034603714 scopus 로고    scopus 로고
    • Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial
    • Zambon, D. et al. 2000. Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial. Ann. Intern. Med. 132: 538-546.
    • (2000) Ann. Intern. Med. , vol.132 , pp. 538-546
    • Zambon, D.1
  • 6
    • 0027473816 scopus 로고
    • Effects of walnuts on serum lipid levels and blood pressure in normal men
    • Sabate, J. et al. 1993. Effects of walnuts on serum lipid levels and blood pressure in normal men.N.Engl. J.Med. 328: 603-607.
    • (1993) N.Engl J.Med. , vol.328 , pp. 603-607
    • Sabate, J.1
  • 7
    • 0031976063 scopus 로고    scopus 로고
    • Adiet rich inwalnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects
    • Chisholm,A. et al. 1998.Adiet rich inwalnuts favourably influences plasma fatty acid profile in moderately hyperlipidaemic subjects. Eur. J. Clin. Nutr. 52: 12-16.
    • (1998) Eur. J. Clin. Nutr. , vol.52 , pp. 12-16
    • Chisholma1
  • 8
    • 9444251094 scopus 로고    scopus 로고
    • Including walnuts in a lowfat/ modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes
    • Tapsell, L.C. et al. 2004. Including walnuts in a lowfat/ modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes. Diabetes Care 27: 2777-2783.
    • (2004) Diabetes Care , vol.27 , pp. 2777-2783
    • Tapsell, L.C.1
  • 9
    • 65549087042 scopus 로고    scopus 로고
    • Nuts and novel biomarkers of cardiovascular disease
    • Ros, E. 2009. Nuts and novel biomarkers of cardiovascular disease. Am. J. Clin. Nutr. 89: 16495-16565.
    • (2009) Am. J. Clin. Nutr. , vol.89 , pp. 16495-16565
    • Ros, E.1
  • 10
    • 0034145133 scopus 로고    scopus 로고
    • Pecans lower lowdensity lipoprotein cholesterol in people with normal lipid levels
    • Morgan,W.A.,& B.J.Clayshulte. 2000. Pecans lower lowdensity lipoprotein cholesterol in people with normal lipid levels. J. Am. Diet. Assoc. 100: 312-318.
    • (2000) J. Am. Diet. Assoc. , vol.100 , pp. 312-318
    • Morgan, W.A.1    Clayshulte, B.J.2
  • 11
    • 0032764677 scopus 로고    scopus 로고
    • Hazelnut supplementation enhances plasma antioxidant potential and lowers plasma cholesterol levels
    • Durak, I. et al. 1999. Hazelnut supplementation enhances plasma antioxidant potential and lowers plasma cholesterol levels. Clin. Chim. Acta 284: 113-115.
    • (1999) Clin. Chim. Acta , vol.284 , pp. 113-115
    • Durak, I.1
  • 12
    • 0032865975 scopus 로고    scopus 로고
    • Associations between diet and cancer, ischemic heart disease, and all-cause mortality in non- Hispanic white California Seventh-day Adventists
    • Fraser, G.E. 1999. Associations between diet and cancer, ischemic heart disease, and all-cause mortality in non- Hispanic white California Seventh-day Adventists. Am. J. Clin. Nutr. 70: 2S-538S.
    • (1999) Am. J. Clin. Nutr. , vol.70
    • Fraser, G.E.1
  • 13
    • 0032856278 scopus 로고    scopus 로고
    • Nuts and their bioactive constituents: Effects on serum lipids and other factors that affect disease risk
    • Kris-Etherton, P.M. et al. 1999. Nuts and their bioactive constituents: effects on serum lipids and other factors that affect disease risk. Am. J. Clin. Nutr. 70: 504S- 511S.
    • (1999) Am. J. Clin. Nutr. , vol.70
    • Kris-Etherton, P.M.1
  • 14
    • 0035163718 scopus 로고    scopus 로고
    • Walnut polyphenolics inhibit in vitro human plasma and LDL oxidation
    • Anderson, K.J. et al. 2001.Walnut polyphenolics inhibit in vitro human plasma and LDL oxidation. J. Nutr. 131: 2837-2842.
    • (2001) J. Nutr. , vol.131 , pp. 2837-2842
    • Anderson, K.J.1
  • 15
    • 0026651085 scopus 로고
    • Wine, alcohol, platelets, and the French paradox for coronary heart disease
    • Renaud, S. & M. de Lorgeril. 1992. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 339: 1523-1526.
    • (1992) Lancet , vol.339 , pp. 1523-1526
    • Renaud, S.1    De Lorgeril, M.2
  • 16
    • 0029868401 scopus 로고    scopus 로고
    • Dietary flavonoids, antioxidant vitamins, and incidence of stroke: The Zutphen study
    • Keli, S.O. et al. 1996. Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study. Arch. Intern. Med. 156: 637-642.
    • (1996) Arch. Intern. Med. , vol.156 , pp. 637-642
    • Keli, S.O.1
  • 17
    • 0028925089 scopus 로고
    • Flavonoid intake and longterm risk of coronary heart disease and cancer in the seven countries study
    • Hertog, M.G. et al. 1995. Flavonoid intake and longterm risk of coronary heart disease and cancer in the seven countries study. Arch. Intern. Med. 155: 381-386.
    • (1995) Arch. Intern. Med. , vol.155 , pp. 381-386
    • Hertog, M.G.1
  • 18
    • 38049080705 scopus 로고    scopus 로고
    • Dietary flavonoid intake and breast cancer survival among women on Long Island
    • Fink, B.N. et al. 2007. Dietary flavonoid intake and breast cancer survival among women on Long Island. Cancer Epidmiol. Biomarkers Prev. 16: 2285-2292.
    • (2007) Cancer Epidmiol. Biomarkers Prev. , vol.16 , pp. 2285-2292
    • Fink, B.N.1
  • 19
    • 51749116013 scopus 로고    scopus 로고
    • Flavonoid intake and the risk of ischaemic stroke and CVD mortality in middle-aged Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study
    • Murso, J. et al. 2008. Flavonoid intake and the risk of ischaemic stroke and CVD mortality in middle-aged Finnish men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Br. J. Nutr. 100: 890-895.
    • (2008) Br. J. Nutr. , vol.100 , pp. 890-895
    • Murso, J.1
  • 20
    • 0031721802 scopus 로고    scopus 로고
    • Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance
    • Bravo, L. 1998. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutr. Rev. 56: 317-333.
    • (1998) Nutr. Rev. , vol.56 , pp. 317-333
    • Bravo, L.1
  • 21
    • 38549136863 scopus 로고    scopus 로고
    • Polyphenolic polyphenols - Just antioxidants ormuch more?
    • Stevenson, D.E. & R.D. Hurst. 2007. Polyphenolic polyphenols - just antioxidants ormuch more? Cell Mol. Life Sci. 64: 2900-2916.
    • (2007) Cell Mol. Life Sci. , vol.64 , pp. 2900-2916
    • Stevenson, D.E.1    Hurst, R.D.2
  • 22
    • 37349062384 scopus 로고    scopus 로고
    • Polyphenols and inflammation: Basic interactions
    • Biesalski, H.K. 2007. Polyphenols and inflammation: basic interactions. Curr. Opin. Clin. Nutr. Metab. Care 10: 724-728.
    • (2007) Curr. Opin. Clin. Nutr. Metab. Care , vol.10 , pp. 724-728
    • Biesalski, H.K.1
  • 23
    • 34047122018 scopus 로고    scopus 로고
    • Further fatalities caused by anaphylactic reactions to food, 2001-2006
    • Bock, S.A., A. Munoz-Furlong, & H.A. Sampson. 2007. Further fatalities caused by anaphylactic reactions to food, 2001-2006. J. Allergy Clin. Immunol. 119: 1016-1018.
    • (2007) J. Allergy Clin. Immunol. , vol.119 , pp. 1016-1018
    • Bock, S.A.1    Munoz-Furlong, A.2    Sampson, H.A.3
  • 25
    • 0033980351 scopus 로고    scopus 로고
    • Tumor necrosis factor in myocardial hypertrophy and ischaemia-an anti-apoptotic perspective
    • Sack, M.N., R.M. Smith, & L.H. Opie. 2000. Tumor necrosis factor in myocardial hypertrophy and ischaemia-an anti-apoptotic perspective. Cardiovasc. Res. 45: 688-695.
    • (2000) Cardiovasc. Res. , vol.45 , pp. 688-695
    • Sack, M.N.1    Smith, R.M.2    Opie, L.H.3
  • 26
    • 33947460027 scopus 로고
    • The polyphenolic constituents of the pellicle of the walnut (Juglans regia)
    • Jurd, L. 1956. The polyphenolic constituents of the pellicle of the walnut (Juglans regia). J. Am. Chem. Soc. 78: 3445-3448.
    • (1956) J. Am. Chem. Soc. , vol.78 , pp. 3445-3448
    • Jurd, L.1
  • 27
    • 0000353241 scopus 로고
    • The isolation of a new ellagitannin fromthe pellicle of the walnut
    • Jurd, L. 1958. The isolation of a new ellagitannin fromthe pellicle of the walnut. J. Am. Chem. Soc. 80: 2249-2252.
    • (1958) J. Am. Chem. Soc. , vol.80 , pp. 2249-2252
    • Jurd, L.1
  • 28
    • 12744274888 scopus 로고    scopus 로고
    • Chemoprotection against Nnitrosomethylbenzylamine- induced mutation in the rat esophagus
    • de Boer, J.G. et al. 2004. Chemoprotection against Nnitrosomethylbenzylamine- induced mutation in the rat esophagus. Nutr. Cancer 50: 168-173.
    • (2004) Nutr. Cancer , vol.50 , pp. 168-173
    • De Boer, J.G.1
  • 29
    • 34547749420 scopus 로고    scopus 로고
    • Effects of various plant polyphenols on bladder carcinogen benzidine-induced mutagenicity
    • Makena, P.S.&K.T.Chung. 2007. Effects of various plant polyphenols on bladder carcinogen benzidine-induced mutagenicity. Food Chem. Toxicol. 45: 1899-1909.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 1899-1909
    • Makena, P.S.1    Chung, K.T.2
  • 30
    • 0041709308 scopus 로고    scopus 로고
    • Low concentrations of querceting and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis inMOLT-4 human leukemia cells
    • Mertens-Talcott, S.U. et al. 2003. Low concentrations of querceting and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis inMOLT-4 human leukemia cells. J. Nutr. 133: 2669-2674.
    • (2003) J. Nutr. , vol.133 , pp. 2669-2674
    • Mertens-Talcott, S.U.1
  • 31
    • 40449114156 scopus 로고    scopus 로고
    • Walnut extract (Juglans regia L.) and its component ellagic acid exhibit antiinflammatory activity in human aorta endothelial cells and osteoblastic activity in the cell line KS483
    • Papoutsi, Z. et al. 2008. Walnut extract (Juglans regia L.) and its component ellagic acid exhibit antiinflammatory activity in human aorta endothelial cells and osteoblastic activity in the cell line KS483.Br. J. Nutr. 99: 715-722.
    • (2008) Br. J. Nutr. , vol.99 , pp. 715-722
    • Papoutsi, Z.1
  • 32
    • 10044262012 scopus 로고    scopus 로고
    • In vitro anti-proliferative activities of ellagic acid
    • Losso, J.N. et al. 2004. In vitro anti-proliferative activities of ellagic acid. J. Nutr. Biochem. 15: 672-678.
    • (2004) J. Nutr. Biochem. , vol.15 , pp. 672-678
    • Losso, J.N.1
  • 33
    • 64749108144 scopus 로고    scopus 로고
    • Effect of ellagic acid on proliferation, cell adhesion and apoptosis in SH-SY5Y human neuroblastoma cells
    • Fjaeraa, C. & E. Nanberg. 2009. Effect of ellagic acid on proliferation, cell adhesion and apoptosis in SH-SY5Y human neuroblastoma cells. Biomed. Pharmacother. 63: 254-261.
    • (2009) Biomed. Pharmacother. , vol.63 , pp. 254-261
    • Fjaeraa, C.1    Nanberg, E.2
  • 34
    • 0031750552 scopus 로고    scopus 로고
    • Plasma concentrations and urinary excretion of the antioxidant flavonols quercetin and kaempferol as biomarkers for dietary intake
    • de Vries, J.H. et al. 1998. Plasma concentrations and urinary excretion of the antioxidant flavonols quercetin and kaempferol as biomarkers for dietary intake. Am. J. Clin. Nutr. 68: 60-65.
    • (1998) Am. J. Clin. Nutr. , vol.68 , pp. 60-65
    • De Vries, J.H.1
  • 35
    • 0032937777 scopus 로고    scopus 로고
    • The bioavailability of non-nutrient plant factors: Dietary flavonoids and phyto-oestrogens
    • Wiseman, H. 1999. The bioavailability of non-nutrient plant factors: dietary flavonoids and phyto-oestrogens. Proc. Nutr. Soc. 58: 139-146.
    • (1999) Proc. Nutr. Soc. , vol.58 , pp. 139-146
    • Wiseman, H.1
  • 36
    • 0032923360 scopus 로고    scopus 로고
    • P53/p21(WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells
    • Narayanan, B.A. et al. 1999. p53/p21(WAF1/CIP1) expression and its possible role in G1 arrest and apoptosis in ellagic acid treated cancer cells. Cancer Lett. 136: 215-221.
    • (1999) Cancer Lett , vol.136 , pp. 215-221
    • Narayanan, B.A.1
  • 37
    • 0035059765 scopus 로고    scopus 로고
    • IGF-II down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid
    • Narayanan, B.A., & G.G. Re. 2001. IGF-II down regulation associated cell cycle arrest in colon cancer cells exposed to phenolic antioxidant ellagic acid. Anticancer Res. 21: 359-364.
    • (2001) Anticancer Res. , vol.21 , pp. 359-364
    • Narayanan, B.A.1    Re, G.G.2
  • 38
    • 0000359845 scopus 로고
    • Colorimetry of total phenolics with phosphomalybdic-phosphotungstic acid reagents
    • Singleton, V.L. & J.A. Rossi. 1965. Colorimetry of total phenolics with phosphomalybdic-phosphotungstic acid reagents. Am. J. Enol. Vitic. 16: 144-158.
    • (1965) Am. J. Enol. Vitic. , vol.16 , pp. 144-158
    • Singleton, V.L.1    Rossi, J.A.2
  • 39
    • 0023991088 scopus 로고
    • Proteinbinding capacity of microquantities of tannins
    • Dawra, R.K., H.P. Makkar, & B. Singh. 1988. Proteinbinding capacity of microquantities of tannins. Anal. Biochem. 170: 50-53.
    • (1988) Anal. Biochem. , vol.170 , pp. 50-53
    • Dawra, R.K.1    Makkar, H.P.2    Singh, B.3
  • 40
    • 0031846740 scopus 로고    scopus 로고
    • Cloning and sequencing of a gene encoding a 2S albumin seed storage protein precursor from English walnut (Juglans regia) - A major food allergen
    • Teuber, S.S., A.M. Dandekar, et al. 1998. Cloning and sequencing of a gene encoding a 2S albumin seed storage protein precursor from English walnut (Juglans regia) - a major food allergen. J. Allergy Clin. Immunol. 101: 807-814.
    • (1998) J. Allergy Clin. Immunol. , vol.101 , pp. 807-814
    • Teuber, S.S.1    Dandekar, A.M.2
  • 41
    • 0033406009 scopus 로고    scopus 로고
    • Identification and cloning of a complementaryDNA encoding a vicilin-like proprotein, Jug r 2, from English walnut kernel (Juglans regia), a major food allergen
    • Teuber, S.S. et al. 1999. Identification and cloning of a complementaryDNA encoding a vicilin-like proprotein, Jug r 2, from English walnut kernel (Juglans regia), a major food allergen. J. Allergy Clin. Immunol. 104: 1311-1320.
    • (1999) J. Allergy Clin. Immunol. , vol.104 , pp. 1311-1320
    • Teuber, S.S.1
  • 42
    • 33751209784 scopus 로고    scopus 로고
    • Jug r 4, a legumin group food allergen from walnut (Juglans regia Cv. Chandler)
    • Wallowitz, M. et al. 2006. Jug r 4, a legumin group food allergen from walnut (Juglans regia Cv. Chandler). J. Agric. Food Chem. 54: 8369-8375.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 8369-8375
    • Wallowitz, M.1
  • 43
    • 0021989459 scopus 로고
    • Inhibition of mast cell histamine release by flavonoids and biflavonoids
    • Amellal, M. et al. 1985. Inhibition of mast cell histamine release by flavonoids and biflavonoids. Planta Med. 1: 16-20.
    • (1985) Planta Med. , vol.1 , pp. 16-20
    • Amellal, M.1
  • 44
    • 0030985591 scopus 로고    scopus 로고
    • Effect of tea polyphenols on histamine release from rat basophilic leukemia (RBL- 2H3) cells: The structure-inhibitory activity relationship
    • Matsuo, N. et al. 1997. Effect of tea polyphenols on histamine release from rat basophilic leukemia (RBL- 2H3) cells: the structure-inhibitory activity relationship. Allergy 52: 58-64.
    • (1997) Allergy , vol.52 , pp. 58-64
    • Matsuo, N.1
  • 45
    • 0025352195 scopus 로고
    • Cellular control of IgE induction by a polyphenol-rich compound. Preferential activation of Th2 cells
    • Baum, C.G. et al. 1990. Cellular control of IgE induction by a polyphenol-rich compound. Preferential activation of Th2 cells. J. Immunol. 145: 779-784.
    • (1990) J. Immunol. , vol.145 , pp. 779-784
    • Baum, C.G.1
  • 46
    • 0033668110 scopus 로고    scopus 로고
    • Antiallergic effect of apple polyphenols on the allergic model mouse
    • Akiyama, H. et al. 2000. Antiallergic effect of apple polyphenols on the allergic model mouse. Biol. Pharm. Bull. 23: 1370-1373.
    • (2000) Biol. Pharm. Bull. , vol.23 , pp. 1370-1373
    • Akiyama, H.1
  • 47
    • 0033928261 scopus 로고    scopus 로고
    • Persimmon leaf extract and astragalin inhibit development of dermatitis and IgE elevation in NC/Nga mice
    • Kotani, M., M. Matsumoto, et al. 2000. Persimmon leaf extract and astragalin inhibit development of dermatitis and IgE elevation in NC/Nga mice. J. Allergy Clin. Immunol. 106: 159-166.
    • (2000) J. Allergy Clin. Immunol. , vol.106 , pp. 159-166
    • Kotani, M.1    Matsumoto, M.2
  • 48
    • 0031831628 scopus 로고    scopus 로고
    • Differential regulation of the Janus kinase-STAT pathway and biologic function of IL-13 in primary humanNKandTcells: A comparative study with IL-4
    • Yu, C.R., R.A. Kirken, et al. 1998. Differential regulation of the Janus kinase-STAT pathway and biologic function of IL-13 in primary humanNKandTcells: a comparative study with IL-4. J. Immunol. 161: 218-227.
    • (1998) J. Immunol. , vol.161 , pp. 218-227
    • Yu, C.R.1    Kirken, R.A.2
  • 49
    • 0033051613 scopus 로고    scopus 로고
    • Differential regulation of antigen-induced IL-4 and IL-13 generation from T lymphocytes by IFN-alpha
    • Essayan,D.M.,G.Krishnaswamy, et al. 1999. Differential regulation of antigen-induced IL-4 and IL-13 generation from T lymphocytes by IFN-alpha. J. Allergy Clin. Immunol. 103: 451-457.
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 451-457
    • Essayan, D.M.1    Krishnaswamy, G.2
  • 50
    • 0033747340 scopus 로고    scopus 로고
    • Regulation of the IgE isotype switch: New insights on cytokine signals and the functions of epsilon germline transcripts
    • Oettgen,H.C. 2000. Regulation of the IgE isotype switch: new insights on cytokine signals and the functions of epsilon germline transcripts. Curr. Opin. Immunol. 12: 618-623.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 618-623
    • Oettgen, H.C.1
  • 51
    • 0035085623 scopus 로고    scopus 로고
    • Variations in serum levels of interleukin (IL)-1beta, IL-2, IL-6, and tumor necrosis factor-alpha during specific immunotherapy
    • De Amici, M., F. Puggioni, et al. 2001. Variations in serum levels of interleukin (IL)-1beta, IL-2, IL-6, and tumor necrosis factor-alpha during specific immunotherapy. Ann. Allergy Asthma Immunol. 86: 311-313.
    • (2001) Ann. Allergy Asthma Immunol. , vol.86 , pp. 311-313
    • De Amici, M.1    Puggioni, F.2
  • 52
    • 0027300847 scopus 로고
    • In vitro effects of natural plant polyphenols on the proliferation of normal and abnormal human lymphocytes and their secretions of interleukin-2
    • Devi, M.A. & N.P. Das. 1993. In vitro effects of natural plant polyphenols on the proliferation of normal and abnormal human lymphocytes and their secretions of interleukin-2. Cancer Lett. 69: 191-196.
    • (1993) Cancer Lett. , vol.69 , pp. 191-196
    • Devi, M.A.1    Das, N.P.2
  • 53
    • 0031149619 scopus 로고    scopus 로고
    • Polyphenols in chocolate, which have antioxidant activity, modulate immune functions in humans in vitro
    • Sanbongi, C., N. Suzuki & T. Sakane. 1997. Polyphenols in chocolate, which have antioxidant activity, modulate immune functions in humans in vitro. Cell Immunol. 177: 129-136.
    • (1997) Cell Immunol. , vol.177 , pp. 129-136
    • Sanbongi, C.1    Suzuki, N.2    Sakane, T.3
  • 54
    • 0033868284 scopus 로고    scopus 로고
    • Cocoa procyanidins and human cytokine transcription and secretion
    • Mao, T., J. van deWater, et al. 2000. Cocoa procyanidins and human cytokine transcription and secretion. J.Nutr. 130: 2093S-2099S.
    • (2000) J.Nutr. , vol.130
    • Mao, T.1    De W.J.Van2
  • 56
    • 0022585016 scopus 로고
    • The effects of flavonoids on human lymphocyte proliferative responses
    • Mookerjee, B.K., T.P. Lee, et al. 1986. The effects of flavonoids on human lymphocyte proliferative responses. Prog. Clin. Biol. Res. 213: 511-520.
    • (1986) Prog. Clin. Biol. Res. , vol.213 , pp. 511-520
    • Mookerjee, B.K.1    Lee, T.P.2
  • 57
    • 0033031943 scopus 로고    scopus 로고
    • Immunosuppressive and anti-inflammatory effects of methanolic extract and the polyacetylene isolated from Bidens pilosa L
    • Pereira, R.L., T. Ibrahim, et al. 1999. Immunosuppressive and anti-inflammatory effects of methanolic extract and the polyacetylene isolated from Bidens pilosa L. Immunopharmacol 43: 31-37.
    • (1999) Immunopharmacol , vol.43 , pp. 31-37
    • Pereira, R.L.1    Ibrahim, T.2
  • 58
    • 0024446740 scopus 로고
    • Effects of synthetic and naturally occurring flavonoids on mitogen-induced proliferation of human peripheral-blood lymphocytes
    • Hirano, T., K. Oka, et al. 1989. Effects of synthetic and naturally occurring flavonoids on mitogen-induced proliferation of human peripheral-blood lymphocytes. Life Sci. 45: 1407-1411.
    • (1989) Life Sci. , vol.45 , pp. 1407-1411
    • Hirano, T.1    Oka, K.2
  • 59
    • 0028158941 scopus 로고
    • Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture
    • Namgoong, S.Y., K.H. Son, et al. 1994. Effects of naturally occurring flavonoids on mitogen-induced lymphocyte proliferation and mixed lymphocyte culture. Life Sci. 54: 313-320.
    • (1994) Life Sci. , vol.54 , pp. 313-320
    • Namgoong, S.Y.1    Son, K.H.2
  • 60
    • 0026759517 scopus 로고
    • Tannins as selective inhibitors of protein kinase C
    • Kashiwada,Y.,G.Nonaka, et al. 1992.Tannins as selective inhibitors of protein kinase C. Bioorg. Med. Chem. Lett. 2: 239-244.
    • (1992) Bioorg. Med. Chem. Lett. , vol.2 , pp. 239-244
    • Kashiwada, Y.1    Nonaka, G.2
  • 61
    • 0027958628 scopus 로고
    • New hexahydroxybiphenyl derivatives as inhibitors of protein kinase C
    • Kashiwada, Y., L. Huang, et al. 1994. New hexahydroxybiphenyl derivatives as inhibitors of protein kinase C. J. Med. Chem. 37: 195-200.
    • (1994) J. Med. Chem. , vol.37 , pp. 195-200
    • Kashiwada, Y.1    Huang, L.2
  • 62
    • 0022494569 scopus 로고
    • The sheep erythrocyte receptor and both alpha and beta chains of the human T-lymphocyte antigen receptor bind the mitogenic lectin (phytohaemagglutinin) from Phaseolus vulgaris
    • Leca, G., L. Boumsell, et al. 1986. The sheep erythrocyte receptor and both alpha and beta chains of the human T-lymphocyte antigen receptor bind the mitogenic lectin (phytohaemagglutinin) from Phaseolus vulgaris. Scand. J. Immunol. 23: 535-544.
    • (1986) Scand. J. Immunol. , vol.23 , pp. 535-544
    • Leca, G.1    Boumsell, L.2
  • 63
    • 0033953745 scopus 로고    scopus 로고
    • [8- (Diethylamino)octyl-3, 4,5-trimethoxybenzoate, HCl], the inhibitor of intracellular calcium mobilization, blocked mitogen-induced T cell proliferation by interfering with the sustained phase of protein kinase C activation
    • Kumar, S., & R. Chakrabarti. 2000. [8- (Diethylamino)octyl-3,4,5- trimethoxybenzoate, HCl], the inhibitor of intracellular calcium mobilization, blocked mitogen-induced T cell proliferation by interfering with the sustained phase of protein kinase C activation. J. Cell Biochem. 76: 539-547.
    • (2000) J. Cell Biochem. , vol.76 , pp. 539-547
    • Kumar, S.1    Chakrabarti, R.2
  • 64
    • 0029894304 scopus 로고    scopus 로고
    • RO 31- 8220, a novel protein kinase C inhibitor, inhibits early and late T cell activation events
    • Geiselhart, L., D.J. Conti & B.M. Freed. 1996. RO 31- 8220, a novel protein kinase C inhibitor, inhibits early and late T cell activation events. Transplantation 61: 1637-1642.
    • (1996) Transplantation , vol.61 , pp. 1637-1642
    • Geiselhart, L.1    Conti, D.J.2    Freed, B.M.3
  • 65
    • 0033784783 scopus 로고    scopus 로고
    • Regulation of cell proliferation, gene expression, production of cytokines, and cell cycle progression in primary human T lymphocytes by piperlactam S isolated from Piper kadsura
    • Kuo, Y.C., N.S. Yang, et al. 2000. Regulation of cell proliferation, gene expression, production of cytokines, and cell cycle progression in primary human T lymphocytes by piperlactam S isolated from Piper kadsura.Mol. Pharmacol. 58: 1057-1066.
    • (2000) Mol. Pharmacol. , vol.58 , pp. 1057-1066
    • Kuo, Y.C.1    Yang, N.S.2
  • 66
    • 0034599923 scopus 로고    scopus 로고
    • Suppression of IL-2 and IL-4 gene expression by nodularin through the reduced NF-AT binding activity
    • Yea, S. S.,H.M. Kim, et al. 2000. Suppression of IL-2 and IL-4 gene expression by nodularin through the reduced NF-AT binding activity. Toxicol. Lett. 114: 215-224.
    • (2000) Toxicol. Lett. , vol.114 , pp. 215-224
    • Yea, S.S.1    Kim, H.M.2
  • 67
    • 0025743920 scopus 로고
    • Protein kinase C regulates both production and secretion of interleukin 2
    • Modiano, J.F., R. Kolp, et al. 1991. Protein kinase C regulates both production and secretion of interleukin 2. J. Biol. Chem. 266: 10552-10561.
    • (1991) J. Biol. Chem. , vol.266 , pp. 10552-10561
    • Modiano, J.F.1    Kolp, R.2
  • 68
    • 0030834548 scopus 로고    scopus 로고
    • Linkage of protein kinase C-beta activation and intracellular interleukin-2 accumulation in human naive CD4 T cells
    • Hassan, J., E. Rainsford, & D.J. Reen. 1997. Linkage of protein kinase C-beta activation and intracellular interleukin-2 accumulation in human naive CD4 T cells. Immunology 92: 465-471.
    • (1997) Immunology , vol.92 , pp. 465-471
    • Hassan, J.1    Rainsford, E.2    Reen, D.J.3
  • 69
    • 0026033409 scopus 로고
    • Differential activation and inhibition of lymphocyte proliferation by modulators of protein kinase C: Diacylglycerols, "rationally designed"
    • Grove,D.S.,& A.M.Mastro. 1991. Differential activation and inhibition of lymphocyte proliferation by modulators of protein kinase C: diacylglycerols, "rationally designed" activators and inhibitors of protein kinase C. Exp. Cell Res. 193: 175-182.
    • (1991) Exp. Cell Res. , vol.193 , pp. 175-182
    • Grove, D.S.1    Mastro, A.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.