Flavonoid intake and the risk of ischaemic stroke and CVD mortality in middle-aged Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study

British Journal of Nutrition

Volumn 100, Issue 4, 2008, Pages 890-895

  Mursu, Jaakko ^a   Voutilainen, Sari ^a   Nurmi, Tarja ^a   Tuomainen, Tomi Pekka ^a   Kurl, Sudhir ^a   Salonen, Jukka T ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b Oy Jurilab Ltd   (Finland)

Author keywords

Cardiovascular disease; Cohort; Diet; Flavonoids; Kuopio ischaemic heart disease risk factor (KIHD) study; Middle aged men; Stroke

Indexed keywords

ALPHA TOCOPHEROL; FLAVAN 3 OL; FLAVAN DERIVATIVE; FLAVONE; FLAVONOID; FLAVONOL; FOLIC ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; UNCLASSIFIED DRUG;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DIETARY INTAKE; FAMILY HISTORY; FAT INTAKE; FINLAND; FOLLOW UP; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY; OXYGEN CONSUMPTION; POPULATION RESEARCH; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RISK FACTOR; RISK REDUCTION; SMOKING; SYSTOLIC BLOOD PRESSURE;

ANTHOCYANINS; CARDIOVASCULAR DISEASES; DIET; EUROPEAN CONTINENTAL ANCESTRY GROUP; FINLAND; FLAVANONES; FLAVONES; FLAVONOIDS; FLAVONOLS; HUMANS; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; RISK FACTORS; STROKE;

EID: 51749116013     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508945694     Document Type: Article

References (31)

1. Ness AR & Powles JW (1997) Fruit and vegetables, and cardiovascular disease: A review. Int J Epidemiol 26, 1-13.
2. Bravo L (1998) Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance. Nutr Rev 56, 317-333.
3. Geleijnse JM, Launer LJ, Van der Kuip DA, Hofman A & Witteman JC (2002) Inverse association of tea and flavonoid intakes with incident myocardial infarction: The Rotterdam Study. Am J Clin Nutr 75 880-886.
4. Hertog M, Sweetnam P, Fehily AM, Elwood PC & Kromhout D (1997) Antioxidant flavonols and ischemic heart disease in Welsh population of men: The Caerphilly study. Am J Clin Nutr 65, 1489-1494.
5. Hertog MG, Feskens EJ & Kromhout D (1997) Antioxidant flavonols and coronary heart disease risk. Lancet 349, 699.
6. Hertog MGL, Feskens EJM, Hollman PCH, Katan MB & Kromhout D (1993) Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen elderly study. Lancet 342, 1007-1011.
7. Knekt P, Järvinen R, Reunanen A & Maatela J (1996) Flavonoid intake and coronary mortality in Finland: A cohort study. Br Med J 312 478-481.
8. Youchum L, Kushi LH, Meyer K & Folsom AR (1999) Dietary flavonoid intake and risk of cardiovascular disease in postmenopausal women. Am J Epidemiol 149, 943-949.
9. Hirvonen T, Pietinen P, Virtanen MM-LO, Häkkinen S, Albanes D & Virtamo J (2001) Intake of flavonols and flavones and risk of coronary heart disease in male smokers. Epidemiology 12, 62-67.
10. Arts IC, Jacobs DRJ, Harnack LJ, Gross M & Folsom AR (2001) Dietary catechins in relation to coronary heart disease death among postmanopausal women. Epidemiology 12, 668-675.
11. Arts IC, Hollman PC, Feskens EJ, Bueno de Mesquita HB & Kromhout D (2001) Catechin intake might explain the inverse relation between tea consumption and ischemic heart disease: The Zutphen Elderly Study. Am J Clin Nutr 74, 227-232.
12. Knekt P, Kumpulainen J, Jarvinen R, Rissanen H, Heliovaara M, Reunanen A, Hakulinen T & Aromaa A (2002) Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 76, 560-568.
13. Sesso HD, Gaziano JM, Uu S & Buring JE (2003) Flavonoid intake and the risk of cardiovascular disease in women. Am J Clin Nutr 77, 1400-1408.
14. Rimm E, Katan M, Ascherio A, Stampfer MJ & Willet WC (1996) Relation between intake of flavonoids and risk of coronary heart disease in male health professionals. Ann Intern Med 125, 384-389.
15. Huxley RR & Neil HA (2003) The relation between dietary flavonol intake and coronary heart disease mortality: A meta-analysis of prospective cohort studies. Eur J Clin Nutr 57, 904-908.
16. Mink PJ, Scrafford CG, Barraj LM, Harnack L, Hong CP, Nettleton JA & Jacobs DRJ (2007) Flavonoid intake and cardiovascular disease mortality: a prospective study in postmenopausal women. Am J Clin Nutr 85 895-909.
17. Keli SO, Hertog MGL, Feskens EJM & Kromhout D (1996) Dietary flavonoids, antioxidant vitamins and incidence of stroke. Arch Intern Med 154, 637-642.
18. Hirvonen T, Virtamo J, Korhonen P, Albanes D & Pietinen P (2000) Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers. Stroke 31, 2301-2306.
19. Dwyer J & Peterson JJ (2002) Measuring flavonoid intake: Need for advanced tools. Public Health Nutr 5, 925-930.
20. US Department of Agriculture (2003) USDA database for the flavonoid content of selected foods. http://www.nal.usda.gov (accessed 12 August 2006).
21. Salonen JT (1988) Is there continuing need for longitudinal epidermiological research? The Kuopio Ischaemic Heart Disease Risk Factor Study. Ann Clin Res 20, 46-50.
22. Lakka TA, Laukkanen JA, Rauramaa R, Salonen R, Lakka H-M, Wan GA & Salonen JT (2001) Cardiorespiratory fitness and the progression of carotid atherosclerosis in middle-aged men. Ann Intern Med 134 12-20.
23. Tunstall-Pedoe H, Kuulasmaa K, Amouyel p, Arveiler D, Rajakangas AM & Pajak A (1904) Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation 90, 583-612.
24. Tuomilehto J, Rastenyte D, Sivenius J, et al. (1996) Ten-year trends in stroke incidence and mortality in the FINMONICA Stroke Study. Stroke 27, 825-832.
25. Kurtl S, Laukkanen JA, Niskanen L, Rauramaa R, Tuomainen TP, Sivenius J & Salonen JT (2005) Cardiac power during exercise and the risk of stroke in men. Stroke 36, 820-824.
26. Willet W & Stampfer M (1998) Implications of total energy intake for epidemiologic analyses. In Nutritional Epidemiology, pp. 273-301 [W Willet, editor]. New York: Oxford University Press.
27. Hodgson JM, Burke V & Puddey IB (2005) Acute effects of tea on fasting and postprandial vascular function and blood pressure in humans. J Hypertens 23, 47-54.
28. Vlachopoulos C, Aznaouridis K, Alexopoulos N, Economou E, Andreadou I & Stefanadis C (2005) Effect of dark chocolate on arterial function in healthy individuals. Am J Hypertens 18, 785-791.
29. Hayek T, Furhman B, Vaya J, Rosenblat M, Belinky P, Coleman R, Elis A & Aviram M (1997) Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation aggregation. Arterioscler Thromb Vasc Biol 17, 2744-2752.
30. Fuhrman B, Volkova N, Coleman R & Aviram M (2005) Grape powder polyphenols attenuate atherosclerosis development in apolipoprotein E deficient (E0) mice and reduce macrophage atherogenicity. J Nutr 135, 722-728.
31. Williamson G & Manach C (2005) Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies. Am J Clin Nutr 81, 243-255.