Suppression of IL-2 and IL-4 gene expression by nodularin through the reduced NF-AT binding activity

Toxicology Letters

Volumn 114, Issue 1-3, 2000, Pages 215-224

  Yea, Sung Su ^a   Kim, Hwan Mook ^b   Jeon, Young Jin ^b   Oh, Hee Mock ^b   Jeong, Hye Gwang ^c   Yang, Kyu Hwan ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Interleukin 2; Interleukin 4; NF AT; Nodularin; T lymphocytes

Indexed keywords

CONCANAVALIN A; CYCLOPEPTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; INTERLEUKIN 4; IONOMYCIN; MESSENGER RNA; NODULARIN; PHORBOL 13 ACETATE 12 MYRISTATE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYANOBACTERIUM; ELECTROPHORETIC MOBILITY; FEMALE; GENE EXPRESSION; IMMUNOTOXICITY; LYMPHOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; T LYMPHOCYTE;

ANIMALS; BACTERIAL TOXINS; BINDING, COMPETITIVE; CELLS, CULTURED; CONCANAVALIN A; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION; HOST CELL FACTOR C1; INTERLEUKIN-2; INTERLEUKIN-4; IONOMYCIN; LYMPHOCYTE ACTIVATION; MICE; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; OCTAMER TRANSCRIPTION FACTOR-1; PEPTIDES, CYCLIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN; T-LYMPHOCYTES; TETRADECANOYLPHORBOL ACETATE; THYMUS GLAND; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS;

CYANOBACTERIA; MURINAE;

EID: 0034599923     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00299-4     Document Type: Article

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