Beyond disgust: Impaired recognition of negative emotions prior to diagnosis in Huntington's disease

Brain

Volumn 130, Issue 7, 2007, Pages 1732-1744

  Johnson, Shannon A ^a,k   Stout, Julie C ^a,l   Solomon, Andrea C ^a   Langbehn, Douglas R ^b   Aylward, Elizabeth H ^c   Cruce, Christina B ^a   Ross, Christopher A ^d   Nance, Martha ^e   Kayson, Elise ^f   Julian Baros, Elaine ^f   Hayden, Michael R ^g   Kieburtz, Karl ^h   Guttman, Mark ⁱ   Oakes, David ^h   Shoulson, Ira ^f   Beglinger, Leigh ^j   Duff, Kevin ^j   Penziner, Elizabeth ^j   Paulsen, Jane S ^j  

^a INDIANA UNIVERSITY   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e HENNEPIN COUNTY MEDICAL CENTER   (United States)

^f UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^g UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^h UNIVERSITY OF ROCHESTER   (United States)

ⁱ UNIVERSITY OF TORONTO   (Canada)

^j UNIVERSITY OF IOWA   (United States)

^k DALHOUSIE UNIVERSITY   (Canada)

^l MONASH UNIVERSITY   (Australia)

more..

Author keywords

Disgust; Emotion recognition; Predict HD; Presymptomatic Huntington's disease; Striatum

Indexed keywords

ADULT; ANGER; ARTICLE; BASAL GANGLION; BRAIN ATROPHY; BRAIN SIZE; COMPUTER ASSISTED DIAGNOSIS; CONTROLLED STUDY; CORPUS STRIATUM; DIAGNOSTIC ACCURACY; DISEASE COURSE; EMOTION; FEAR; FEMALE; HUMAN; HUNTINGTON CHOREA; INSULA; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RESEARCH; MENTAL TASK; PRIORITY JOURNAL; RECOGNITION; TASK PERFORMANCE; CLINICAL TRIAL; FACIAL EXPRESSION; METHODOLOGY; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PATTERN RECOGNITION; PERCEPTION; PHOTOSTIMULATION; PSYCHOLOGICAL ASPECT; REACTION TIME;

ADULT; ANGER; CORPUS STRIATUM; DISEASE PROGRESSION; EMOTIONS; FACIAL EXPRESSION; FEAR; FEMALE; HUMANS; HUNTINGTON DISEASE; MAGNETIC RESONANCE IMAGING; MALE; PATTERN RECOGNITION, VISUAL; PHOTIC STIMULATION; REACTION TIME; RECOGNITION (PSYCHOLOGY); SOCIAL PERCEPTION;

EID: 34447620858     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awm107     Document Type: Article

References (49)

1. Adolphs R. Neural systems for recognizing emotion. Curr Opin Neurobiol 2002; 12: 169-77.
2. Agresti A. Categorical data analysis. New York: Wiley; 1990. p. 322-4.
3. Aylward EH, Codori AM, Barta PE, Pearlson GD, Harris GJ, Brandt J. Basal ganglia volume and proximity to onset in presymptomatic Huntington disease. Arch Neurol 1996; 53: 1293-6.
4. Aylward EH, Codori AM, Rosenblatt A, Sherr M, Brandt J, Stine OC, et al. Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease. Mov Disord 2000; 15: 552-60.
5. Aylward EH, Li Q, Stine OC, Ranen N, Sherr M, Barta PE, et al. Longitudinal change in basal ganglia volume in patients with Huntington's disease. Neurology 1997; 48: 394-9.
6. Bartholomew DJ, Knott M. Polytomous data: latent trait models. Kendall's library of Statistics 7: latent variable models and factor analysis. 2nd edn., London: Arnold; 1999. p. 103-32.
7. Beck AT, Steer RA, Brown GK. Beck depression inventory-II: the psychological corporation; 1996..
8. Beglinger LJ, Nopoulos PC, Jorge RE, Langbehn DR, Mikos AE, Moser DJ, et al. White matter volume and cognitive dysfunction in early Huntington's disease. Cogn Behav Neurol 2005; 18: 102-7.
9. Benton AL, Sivan AB, Hamsher KD, Varney NR, Spreen O. Contributions to neuropsychological assessment. New York: Oxford University Press; 1994.
10. Calder A, Keane J, Manes F, Antoun N, Young AW. Impaired recognition and experience of disgust following brain injury. Nat Neurosci 2000; 3: 1077-8.
11. Calder A, Lawrence AD, Young AW. Neuropsychology of fear and loathing. Nat Rev Neurosci 2001; 2: 352-63.
12. Carlozzi N, Stout JC, Queller S, Solomon A, Duff K, Beglinger L, et al. Assessment of intellectual functioning in pre-diagnostic Huntington's disease. J Int Neuropsychol Soc 2007; 13(S1): 103.
13. Ekman P, Friesen WV. Pictures of facial affect. Palo Alto, CA: Consulting Psychological Press; 1976.
14. Feigin A, Ghilardi MF, Huang C, Ma Y, Carbon M, Guttman M, et al. Preclinical Huntington's disease: compensatory brain responses during learning. Ann Neurol 2006; 59: 53-9.
15. Gray JM, Young AW, Barker WA, Curtis A, Gibson D. Impaired recognition of disgust in Huntington's disease gene carriers. Brain 1997; 120: 2029-38.
16. Grober E, Sliwinski M. Development and validation of a model for estimating premorbid verbal intelligence in the elderly. J Clin Exp Neuropsychol 1991; 13: 933-49.
17. Haidt J, McCauley C, Rozin P. Individual differences in sensitivity to disgust: a scale sampling seven domains of disgust elicitors. Pers Individ Dif 1994; 16: 701-13.
18. Hennenlotter A, Schroeder U, Erhard P, Haslinger B, Stahl R, Weindl A, et al. Neural correlates associated with impaired disgust processing in pre-symptomatic Huntington's disease. Brain 2004; 127: 1446-53.
19. Huntington Study Group. Unified Huntington's Disease Rating Scale: reliability and consistency. Mov Disord 1996; 11: 136-42.
20. Johnston PJ, Katsikitis M, Carr VJ. A generalised deficit can account for problems in facial emotion recognition in schizophrenia. Biol Psychol 2001; 58: 203-27.
21. Kan Y, Mimura M, Kamijima K, Kawamura M. Recognition of emotion from moving facial and prosodic stimuli in depressed patients. J Neurol Neurosurg Psychiatry 2004; 75: 1667-71.
22. Katsikitis M. The classification of facial expressions of emotion. A multidimensional scaling approach. Perception 1997; 26: 613-26.
23. Kaufman L, Rousseeuw PJ. Finding groups in data: an introduction to cluster analysis. New York: Wiley; 1990.
24. Langbehn DR, Brinkman RR, Falush D, Paulsen JS, Hayden MR. International Huntington's Disease Collaborative Group. A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clin Genet 2004; 65: 267-77.
25. Langenecker SA, Bieliauskas LA, Rapport LJ, Zubieta J, Wilde EA, Berent S. Face emotion perception and executive functioning deficits in depression. J Clin Exp Neuropsychol 2005; 27: 320-33.
26. MacQueen J. Some methods for classification and analysis of multivariate observations. In: Le Cam LM, Neyman J, editors. Proceedings of the Fifth Berkeley Symposium on Mathematical Statistics and Probability. Vol. 1. Berkeley, California: University of California Press; 1967. p. 281-97.
27. Mcullach P. Regression models for ordinal data. J R Stat Soc Ser B Method 1980; 42: 109-42.
28. Milders M, Crawford JR, Lamb A, Simpson SA. Differential deficits in expression recognition in gene-carriers and patients with Huntington's disease. Neuropsychologia 2003; 41: 1484-92.
29. Montagne B, Kessels RPC, Kammers MPM, Kingma E, de Haan EHF, Roos RAC, et al. Perception of emotional facial expressions at different intensities in early-symptomatic Huntington's disease. Eur Neurol 2006; 55: 151-4.
30. Muthen LK, Muthen BO. Mplus user's guide. Los Angeles: Muthen and Muthen; 2001.
31. Paulsen JS, Hayden M, Stout JC, Langbehn DR, Aylward E, Ross CA, et al. Preparing for preventive clinical trials: the Predict-HD study. Arch Neurol 2006a; 63: 883-90.
32. Paulsen JS, Magnotta VA, Mikos AE, Paulson HL, Penziner E, Andreasen NC, et al. Brain structure in preclinical Huntington's disease. Biol Psychiatry 2006b; 59: 57-63.
33. Paulsen JS, Zimbelman JL, Hinton SC, Langbehn DR, Leveroni CL, Benjamin ML, et al. fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's Disease. Am J Neuroradiol 2004; 25: 1715-21.
34. Peinemann A, Schuller S, Pohl C, Jahn T, Weindl A, Kassubek J. Executive dysfunction in early stages of Huntington's disease is associated with striatal and insular atrophy: a neuropsychological and voxel-based morphometric study. J Neurol Sci 2005; 239: 11-9.
35. Phillips ML, Young AW, Scott SK, Calder AJ, Andrew C, Giampietro V, et al. Neural responses to facial and vocal expressions of fear and disgust. Proc Biol Sci 1998; 265: 1809-17.
36. Phillips ML, Young AW, Senior C, Brammer M, Andrew C, Calder AJ, et al. A specific neural substrate for perceiving facial expressions of disgust. Nature 1997; 389: 495-8.
37. Reading SA, Dziorny AD, Peroutka LA, Schreiber M, Gourley LM, Yallapragada V, et al. Functional brain changes in presymptomatic Huntington's disease. Ann Neurol 2004; 55: 879-83.
38. Reading SA, Yassa MA, Bakker A, Dziorny AC, Gourley LM, Yallapragada V, et al. Regional white matter change in pre-symptomatic Huntington's disease: a diffusion tensor imaging study. Psychiatry Res 2005; 140: 55-62.
39. Rosas HD, Hevelone ND, Zaleta AK, Greve DN, Salat DH, Fischl B. Regional cortical thinning in preclinical Huntington disease and it relationship to cognition. Neurology 2005; 65: 745-7.
40. Rosas HD, Koroshetz WJ, Chen YI, Skeuse C, Vangel M, Cudkowicz ME, et al. Evidence for more widespread cerebral pathology in early HD: An MRI-based morphometric analysis. Neurology 2003; 60: 1615-20.
41. Shapira NA, Liu Y, He AG, Bradley MM, Lessig MC, James GA, et al. Brain activation by disgust-inducing pictures in obsessive-compulsive disorder. Biol Psychiatry 2003; 54: 751-6.
42. Sprengelmeyer R, Rausch M, Eysel UT, Przuntek H. Neural structures associated with recognition of facial expressions of basic emotions. Proc Biol Sci 1998; 265: 1927-31.
43. Sprengelmeyer R, Schroeder U, Young AW, Epplen JT. Disgust in preclinical Huntington's disease: A longitudinal study. Neuropsychologia 2006; 44: 518-33.
44. Sprengelmeyer R, Young AW, Calder AJ, Karnat A, Lange H, Homberg V, et al. Loss of disgust: perception of faces and emotions in Huntington's disease. Brain 1996; 119: 1647-65.
45. Sprengelmeyer R, Young AW, Pundt I, Sprengelmeyer A, Calder AJ, Berrios G, et al. Disgust implicated in obsessive-compulsive disorder. Proc Biol Sci 1997a; 264: 1767-73.
46. Sprengelmeyer R, Young AW, Sprengelmeyer A, Calder AJ, Rowland D, Perrett D, et al. Recognition of facial expressions: Selective impairment of specific emotions in Huntington's disease. Cogn Neuropsychol 1997b; 14: 839-79.
47. Surguladze S, Brammer MJ, Keedwell P, Giampietro V, Young AW, Travis MJ, et al. A differential pattern of neural response toward sad versus happy facial expressions in major depressive disorder. Biol Psychiatry 2005; 57: 201-9.
48. Thieben MJ, Duggins AJ, Good CD, Gomes L, Mahant N, Richards F, et al. The distribution of structural neuropathology in pre-clinical Huntington's disease. Brain 2002; 125: 1815-28.
49. Wang K, Hoosain R, Yang RM, Meng Y, Wang CQ. Impairment of recognition of disgust in Chinese with Huntington's or Wilson's disease. Neuropsychologia 2003; 41: 527-37.