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Volumn , Issue 10, 2010, Pages 1999-2007

Facile assembly of fused isoquinolines by gold(i)-catalyzed coupling-cyclization reactions between o-alkynylbenzaldehydes and aromatic amines containing tethered nucleophiles

Author keywords

Alkynes; Cyclization; Fused ring systems; Gold; Nitrogen heterocycles; Polycycles

Indexed keywords


EID: 77949823220     PISSN: 1434193X     EISSN: 10990690     Source Type: Journal    
DOI: 10.1002/ejoc.200901364     Document Type: Article
Times cited : (87)

References (78)
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    • For the X-ray crystal structure of 3c, see the Supporting Information.
    • For the X-ray crystal structure of 3c, see the Supporting Information.
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    • For the X-ray crystal structure of 3q, see the Supporting Information.
    • For the X-ray crystal structure of 3q, see the Supporting Information.
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    • note
    • We are thankful to one of the referees for their valuable suggestions. They suggested one way to determine the difference between the two mechanisms is to look into the phenyl group that has an electron-donating group at the ortho position. This should increase the steric bulkiness of the phenyl group and facilitate the formation, of the minium ion but slow down the 6re electrocyclization. Unfortunately, the present protocol is not applicable to the substrates bearing substituents at the ortho position of the phenyl rings.
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    • For the X-ray crystal structure of 3w, see the Supporting Information.
    • For the X-ray crystal structure of 3w, see the Supporting Information.
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    • The condensation is a catalyzed process, as can be judged by the outcome of the reaction mentioned in Table 1, Entry 11.
    • The condensation is a catalyzed process, as can be judged by the outcome of the reaction mentioned in Table 1, Entry 11.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.