MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain

Molecular and Cellular Neuroscience

Volumn 39, Issue 3, 2008, Pages 356-371

  Lindholm, Päivi ^a   Peränen, Johan ^a   Andressoo, Jaan Olle ^a   Kalkkinen, Nisse ^a   Kokaia, Zaal ^b   Lindvall, Olle ^b   Timmusk, Tõnis ^a,c   Saarma, Mart ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

^c TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

Author keywords

ARMET; CDNF; Dopaminergic; Expression; Immunohistochemistry; Ischemia; MANF; Status epilepticus

Indexed keywords

MESENCEPHALIC ASTROCYTE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NEUROTROPHIC FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN NERVE CELL; EPILEPTIC STATE; EXPERIMENTAL ANIMAL; GENE EXPRESSION; GRANULE CELL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAMMAL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PURKINJE CELL; RODENT;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; BRAIN ISCHEMIA; CELL LINE; CELL SURVIVAL; EMBRYO, MAMMALIAN; EPILEPSY; GENE EXPRESSION REGULATION; HUMANS; IN SITU HYBRIDIZATION; MICE; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; TISSUE DISTRIBUTION;

MAMMALIA; RODENTIA;

EID: 53849102168     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2008.07.016     Document Type: Article

References (44)

1. Airaksinen M.S., and Saarma M. The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci. 3 (2002) 383-394
2. Arenas E., Trupp M., Åkerud P., and Ibáñez C.F. GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo. Neuron 15 (1995) 1465-1473
3. Arvidsson A., Kokaia Z., Airaksinen M.S., Saarma M., and Lindvall O. Stroke induces widespread changes of gene expression for glial cell line-derived neurotrophic factor family receptors in the adult rat brain. Neuroscience 106 (2001) 27-41
4. Bespalov M.M., and Saarma M. GDNF family receptor complexes are emerging drug targets. Trends Pharmacol. Sci. 28 (2007) 68-74
5. Binder D.K., Croll S.D., Gall C.M., and Scharfman H.E. BDNF and epilepsy: too much of a good thing?. Trends Neurosci 24 (2001) 47-53
6. Burke R.E. Postnatal developmental programmed cell death in dopamine neurons. Ann. N. Y. Acad. Sci. 991 (2003) 69-79
7. Gash D.M., Zhang Z., Ovadia A., Cass W.A., Yi A., Simmerman L., Russell D., Martin D., Lapchak P.A., Collins F., Hoffer B.J., and Gerhardt G.A. Functional recovery in parkinsonian monkeys treated with GDNF. Nature 380 (1996) 252-255
8. Gill S.S., Patel N.K., Hotton G.R., O'Sullivan K., McCarter R., Bunnage M., Brooks D.J., Svendsen C.N., and Heywood P. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat. Med. 9 (2003) 589-595
9. Grondin R., Zhang Z., Yi A., Cass W.A., Maswood N., Andersen A.H., Elsberry D.D., Klein M.C., Gerhardt G.A., and Gash D.M. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain 125 (2002) 2191-201
10. Gustafsson E., Lindvall O., and Kokaia Z. Intraventricular infusion of TrkB-Fc fusion protein promotes ischemia-induced neurogenesis in adult rat dentate gyrus. Stroke 34 (2003) 2710-2715
11. Ernfors P., Bengzon J., Kokaia Z., Persson H., and Lindvall O. Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis. Neuron 7 (1991) 165-176
12. Hoffer B.J., Hoffman A., Bowenkamp K., Huettl P., Hudson J., Martin D., Lin L.F., and Gerhardt G.A. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neurosci. Lett. 182 (1994) 107-111
13. Huang E.J., and Reichardt L.F. Neurotrophins: roles in neuronal development and function. Annu. Rev. Neurosci. 24 (2001) 677-736
14. Jakubs K., Nanobashvili A., Bonde S., Ekdahl C.T., Kokaia Z., Kokaia M., and Lindvall O. Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability. Neuron 52 (2006) 1047-1059
15. Jin G., Omori N., Li F., Nagano I., Manabe Y., Shoji M., and Abe K. Protection against ischemic brain damage by GDNF affecting cell survival and death signals. Neurol. Res. 25 (2003) 249-253
16. Kearns C.M., and Gash D.M. GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo. Brain Res. 672 (1995) 104-111
17. Kokaia Z., and Lindvall O. Neurogenesis after ischaemic brain insults. Curr. Opin. Neurobiol. 13 (2003) 127-132
18. Kokaia Z., Airaksinen M.S., Nanobashvili A., Larsson E., Kujamäki E., Lindvall O., and Saarma M. GDNF family ligands and receptors are differentially regulated after brain insults in the rat. Eur. J. Neurosci. 11 (1999) 1202-1216
19. Kramer E.R., Aron L., Ramakers G.M., Seitz S., Zhuang X., Beyer K., Smidt M.P., and Klein R. Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol. 5 (2007) e39 doi:10.1371
20. Krieglstein K. Factors promoting survival of mesencephalic dopaminergic neurons. Cell. Tissue Res. 318 (2004) 73-80
21. Kuipers S.D., and Bramham C.R. Brain-derived neurotrophic factor mechanisms and function in adult synaptic plasticity: new insights and implications for therapy. Curr. Opin. Drug Discov. Devel. 9 (2006) 580-586
22. Lang A.E., Gill S., Patel N.K., Lozano A., Nutt J.G., Penn R., Brooks D.J., Hotton G., Moro E., Heywood P., Brodsky M.A., Burchiel K., Kelly P., Dalvi A., Scott B., Stacy M., Turner D., Wooten V.G., Elias W.J., Laws E.R., Dhawan V., Stoessl A.J., Matcham J., Coffey R.J., and Traub M. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann. Neurol. 59 (2006) 459-466
23. Lin L.F., Doherty D.H., Lile J.D., Bektesh S., and Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260 (1993) 1130-1132
24. Lindholm P., Voutilainen M.H., Laurén J., Peränen J., Leppänen V.M., Andressoo J.O., Lindahl M., Janhunen S., Kalkkinen N., Timmusk T., Tuominen R.K., and Saarma M. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. Nature 448 (2007) 73-77
25. Lindvall O., Ernfors P., Bengzon J., Kokaia Z., Smith M.L., Siesjö B.K., and Persson H. Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc. Natl. Acad. Sci. USA 89 (1992) 648-652
26. Lothman E.W., Bertram E.H., Bekenstein J.W., and Perlin J.B. Self-sustaining limbic status epilepticus induced by continuous hippocampal stimulation: electrographic and behavioral characteristics. Epilepsy Res. 3 (1989) 107-119
27. Mizobuchi N., Hoseki J., Kubota H., Toyokuni S., Nozaki J., Naitoh M., Koizumi A., and Nagata K. ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element. Cell Struct. Funct. 32 (2007) 41-50
28. Oo T.F., and Burke R.E. The time course of developmental cell death in phenotypically defined dopaminergic neurons of the substantia nigra. Brain Res. Dev. Brain Res. 98 (1997) 191-196
29. Patel N.K., Bunnage M., Plaha P., Svendsen C.N., Heywood P., and Gill S.S. Intraputamenal infusion of glial cell line-derived neurotrophic factor in PD: a two-year outcome study. Ann. Neurol. 57 (2005) 298-302
30. Petrova P.S., Raibekas A., Pevsner J., Vigo N., Anafi M., Moore M.K., Peaire A.E., Shridhar V., Smith D.I., Kelly J., Durocher Y., and Commissiong J.W. MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J. Mol. Neurosci. 20 (2003) 173-187
31. Peränen J., and Furuhjelm J. Expression, purification and properties of Rab8 function in actin cortical skeleton organization and polarized transport. Methods Enzymol. 329 (2001) 188-196
32. Peränen J., Rikkonen M., Hyvönen M., and Kääriäinen L. T7 vectors with a modified T7lac promoter for expression of proteins in Escherichia coli. Anal. Biochem. 236 (1996) 371-373
33. Poutanen M., Salusjärvi L., Ruohonen L., Penttilä M., and Kalkkinen N. Use of matrix-assisted laser desorption/ionization time-of-flight mass mapping and nanospray liquid chromatography/electrospray ionization tandem mass spectrometry sequence tag analysis for high sensitivity identification of yeast proteins separated by two-dimensional gel electrophoresis. Rapid Commun. Mass Spectrom. 15 (2001) 1685-1692
34. Racine R.J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32 (1972) 281-294
35. Reeben M., Laurikainen A., Hiltunen J.O., Castrén E., and Saarma M. The messenger RNAs for both glial cell line-derived neurotrophic factor receptors, c-RET and GDNFRα, are induced in the rat brain in response to kainite-induced excitation. Neuroscience 83 (1998) 151-159
36. Sauer H., Rosenblad C., and Björklund A. Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc. Natl. Acad. Sci. USA 92 (1995) 8935-8939
37. Schaar D.G., Sieber B.A., Dreyfus C.F., and Black I.B. Regional and cell-specific expression of GDNF in rat brain. Exp. Neurol. 124 (1993) 368-371
38. Schäbitz W.R., Steigleder T., Cooper-Kuhn C.M., Schwab S., Sommer C., Schneider A., and Kuhn H.G. Intravenous brain-derived neurotrophic factor enhances poststroke sensorimotor recovery and stimulates neurogenesis. Stroke 38 (2007) 2165-2172
39. Smith M.L., Auer R.N., and Siesjö B.K. The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol. 64 (1984) 319-332
40. Springer J.E., Mu X., Bergmann L.W., and Trojanowski J.Q. Expression of GDNF mRNA in rat and human nervous tissue. Exp. Neurol. 127 (1994) 167-170
41. Strömberg I., Björklund L., Johansson M., Tomac A., Collins F., Olson L., Hoffer B., and Humpel C. Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo. Exp. Neurol. 124 (1993) 401-412
42. Suvanto P., Hiltunen J.O., Arumäe U., Moshnyakov M., Sariola H., Sainio K., and Saarma M. Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization. Eur. J. Neurosci. 8 (1996) 816-822
43. Tomac A., Lindqvist E., Lin L.F., Ögren S.O., Young D., Hoffer B.J., and Olson L. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 373 (1995) 335-339
44. Trupp M., Ryden M., Jornvall H., Funakoshi H., Timmusk T., Arenas E., and Ibanez C.F. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J. Cell Biol. 130 (1995) 137-148