Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 7, 2009, Pages 2429-2434

  Palgi, Mari ^a   Lindström, Riitta ^a   Peränen, Johan ^a   Piepponen, T Petteri ^b   Saarma, Mart ^a   Heino, Tapio I ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Development; Dopamine; Drosophila; Glia; Neurite

Indexed keywords

DROSOPHILA PROTEIN; NEUROTROPHIC FACTOR; PROTEIN DMMANF; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CENTRAL NERVOUS SYSTEM; DOPAMINERGIC NERVE CELL; DROSOPHILA; INVERTEBRATE; NERVE FIBER DEGENERATION; PARKINSON DISEASE; PRIORITY JOURNAL;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; DOPAMINE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURITES; NEURONS; PARKINSON DISEASE; SEQUENCE HOMOLOGY, AMINO ACID;

INVERTEBRATA; MAMMALIA; VERTEBRATA;

EID: 60549115250     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0810996106     Document Type: Article

References (48)

1. Loughlin SE, Fallon JH (1993) Neurotrophic Factors (Academic, San Diego), p 599.
2. Evans JR, Barker RA (2008) Neurotrophic factors as a therapeutic target for Parkinson's disease. Expert Opin Ther Targets 12:437-447.
3. Bothwell M (2006) Evolution of the neurotrophin signaling system in invertebrates. Brain Behav Evol 68:124-132.
4. Benito-Gutierrez E, Garcia-Fernandez J, Comella JX (2006) Origin and evolution of the Trk family of neurotrophic receptors. Mol Cell Neurosci 31:179-192.
5. Sugaya R, Ishimaru S, Hosoya T, Saigo K, Emori Y (1994) A Drosophila homolog of human proto-oncogene ret transiently expressed in embryonic neuronal precursor cells including neuroblasts and CNS cells. Mech Dev 45:139-145.
6. Airaksinen MS, Holm L, Hätinen T (2006) Evolution of the GDNF family ligands and receptors. Brain Behav Evol 68:181-190.
7. Zhu B, et al. (2008) Drosophila neurotrophins reveal a common mechanism for nervous system formation. PLoS Biol 6:e284.
8. Prokop A, Bray S, Harrison E, Technau GM (1998) Homeotic regulation of segment-specific differences in neuroblast numbers and proliferation in the Drosophila central nervous system. Mech Dev 74:99-110.
9. Bello BC, Hirth F, Gould AP (2003) A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis. Neuron 37:209-219.
10. Lundell MJ, Lee HK, Perez E, Chadwell L (2003) The regulation of apoptosis by Numb/Notch signaling in the serotonin lineage of Drosophila. Development 130:4109-4121.
11. Miguel-Aliaga I, Thor S (2004) Segment-specific prevention of pioneer neuron apoptosis by cell-autonomous, postmitotic Hox gene activity. Development 131:6093-6105.
12. Bergmann A, Tugentman M, Shilo BZ, Steller H (2002) Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling. Dev Cell 2:159-170.
13. Hidalgo A, Kinrade EF, Georgiou M (2001) The Drosophila neuregulin vein maintains glial survival during axon guidance in the CNS. Dev Cell 1:679-690.
14. Sepp KJ, Auld VJ (2003) Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development. J Neurosci 23:8221-8230.
15. Booth GE, Kinrade EF, Hidalgo A (2000) Glia maintain follower neuron survival during Drosophila CNS development. Development 127:237-244.
16. Petrova P, et al. (2003) MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. J Mol Neurosci 20:173-188.
17. Lindholm P, et al. (2007) Novel neurotrophic factor CDNF protects and rescues midbrain dopaminergic neurons in vivo. Nature 448:73-77.
18. Apostolou A, Shen Y, Liang Y, Luo J, Fang S (2008) Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death. Exp Cell Res 314:2454-2467.
19. Wright TR (1987) The genetics of biogenic amine metabolism, sclerotization, and melanization in Drosophila melanogaster. Adv Genet 24:127-222.
20. Urban J, Technau GM (1997) Cell lineage and cell fate specification in the embryonic CNS of Drosophila. Semin Cell Dev Biol 8:391-400.
21. Ito K, Urban J, Technau GM (1995) Distribution, classification and development of Drosophila glial cells during late embryogenesis. Rouxs Arch Dev Biol 204:284-307.
22. Bellen HJ, et al. (2004) The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics 167:761-781.
23. Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
24. Chou TB, Perrimon N (1996) The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144:1673-1679.
25. Friggi-Grelin F, et al. (2003) Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase. J Neurobiol 54:618-627.
26. Budnik V, Martin-Morris L, White K (1986) Perturbed pattern of catecholamine-containing neurons in mutant Drosophila deficient in the enzyme dopa decarboxylase. J Neurosci 6:3682-3691.
27. Landgraf M, Sanchez-Soriano N, Technau GM, Urban J, Prokop A (2003) Charting the Drosophila neuropile: a strategy for the standardised characterisation of genetically amenable neurites. Dev Biol 260:207-225.
28. Budnik V, White K (1988) Catecholamine-containing neurons in Drosophila melanogaster: Distribution and development. J Comp Neurol 268:400-413.
29. Payre F (2004) Genetic control of epidermis differentiation in Drosophila. Int J Dev Biol 48:207-215.
30. Raff M, Whitmore A, Finn J (2002) Axonal self-destruction and neurodegeneration. Science 296:868-871.
31. Clarke PG (1990) Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol 195-213.
32. Wang HQ, Takahashi R (2007) Expanding insights on the involvement of endoplasmic reticulum stress in Parkinson's disease. Antioxid Redox Signal 9:553-561.
33. Watts RJ, Schuldiner O, Perrino J, Larsen C, Luo L (2004) Glia engulf degenerating axons during developmental axon pruning. Curr Biol 14:678-684.
34. MacDonald JM, et al. (2006) The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons. Neuron 50:869-881.
35. Awasaki T, et al. (2006) Essential role of the apoptotic cell engulfment genes draper and ced-6 in programmed axon pruning during Drosophila metamorphosis. Neuron 50:855-867.
36. Whitworth A, Wes P, Pallanck L (2006) Drosophila models pioneer a new approach to drug discovery for Parkinson's disease. Drug Discov Today 11:119-126.
37. Coulom H, Birman S (2004) Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. J Neurosci 24:10993-10998.
38. Wodarz A, Hinz U, Engelbert M, Knust E (1995) Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila. Cell 82:67-76.
39. O'Donnell KH, Chen CT, Wensink PC (1994) Insulating DNA directs ubiquitous transcription of the Drosophila melanogaster alpha 1-tubulin gene. Mol Cell Biol 14:6398-6408.
40. Fujioka M, et al. (2003) Even-skipped, acting as a repressor, regulates axonal projections in Drosophila. Development 130:5385-5400.
41. Hrdlicka L, et al. (2002) Analysis of twenty-four Gal4 lines in Drosophila melanogaster. Genesis 4:51-57.
42. Zhou L, et al. (1997) Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells. Proc Natl Acad Sci USA 94:5131-5136.
43. Peränen J, Furuhjelm J (2001) Expression, purification, and properties of Rab8 function in actin cortical skeleton organization and polarized transport. Methods Enzymol 329:188-196.
44. Peränen J, Rikkonen M, Hyvönen M, Kääriäinen L (1996) T7 vectors with modified T7lac promoter for expression of proteins in Escherichia coli. Anal Biochem 236:371-373.
45. Patel NH (1994) Imaging neuronal subsets and other cell types in whole-mount Drosophila embryos and larvae using antibody probes. Methods Cell Biol 44:445-487.
46. Palgi J, Stumpf E, Otonkoski T (2000) Transcription factor expression and hormone production in pancreatic AR42J cells. Mol Cell Endocrinol 165:41-49.
47. Budnik V, Gorczyca M, Prokop A (2006) Selected methods for the anatomical study of Drosophila embryonic and larval neuromuscular junctions. Int Rev Neurobiol 75:323-365.
48. Airavaara M, et al. (2006) In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered. Synapse 59:321-329.