Lactacidosis modulates glutathione metabolism and oxidative glutamate toxicity

Journal of Neurochemistry

Volumn 113, Issue 2, 2010, Pages 502-514

  Lewerenz, Jan ^a   Dargusch, Richard ^b   Maher, Pamela ^b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Acidosis; Glutathione; Lactate; Neuroprotection; Oxidative stress

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACETYLCYSTEINE; ACIVICIN; CYSTINE; FISETIN; GLUTAMIC ACID; GLUTATHIONE; LACTIC ACID; QUERCETIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; GLUTATHIONE METABOLISM; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; LACTIC ACIDOSIS; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ACIDOSIS; ANIMALS; ANTIOXIDANTS; ASTROCYTES; CELL LINE, TRANSFORMED; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CYSTINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; FLAVONOIDS; GLUTAMIC ACID; GLUTATHIONE; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MICE; NEURONS; OXIDATIVE STRESS; QUERCETIN; SULFUR ISOTOPES; TIME FACTORS; TRITIUM;

ANIMALIA;

EID: 77949678956     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06621.x     Document Type: Article

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