Noncatalytic interactions between glutathione S-transferases and nitroalkene fatty acids modulate nitroalkene-mediated activation of peroxisomal proliferator-activated receptor γ

Biochemistry

Volumn 48, Issue 19, 2009, Pages 4159-4169

  Bates, Darcy J P ^a   Lively, Mark O ^a   Gorczynski, Michael J ^b   King, S Bruce ^b   Townsend, Alan J ^a   Morrow, Charles S ^a,b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR RESPONSE; COVALENT BOND FORMATION; GLUTATHIONE; GLUTATHIONE S-TRANSFERASES; MCF-7 CELLS; NANOMOLAR RANGE; NATURALLY OCCURRING; NITROALKENES; NON-CATALYTIC; NON-ENZYMATIC; NUCLEAR TARGETS; OA TREATMENT; POTENT INHIBITION; PROLIFERATOR; REPORTER GENE;

ACIDS; BIOCHEMISTRY; ENZYMES; FATTY ACIDS; LIGANDS; SYSTEM THEORY;

TRANSCRIPTION;

FATTY ACID DERIVATIVE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE A4; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; MULTIDRUG RESISTANCE PROTEIN 1; NITROLINOLEIC ACID; NITROOLEIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL STRAIN MCF 7; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; TRANSCRIPTION INITIATION;

ALKENES; BREAST NEOPLASMS; CELL LINE, TUMOR; FATTY ACIDS; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; KINETICS; NITRO COMPOUNDS; PPAR GAMMA; RECOMBINANT PROTEINS; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 66049125104     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900224c     Document Type: Article

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