메뉴 건너뛰기




Volumn 71, Issue 1, 1998, Pages 95-105

Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells

Author keywords

Apoptosis; Caspase; Glutamate toxicity; Glutathione; Protein kinase C

Indexed keywords

AURINTRICARBOXYLIC ACID; CYCLOHEXIMIDE; DACTINOMYCIN; GLUTAMIC ACID; GLUTATHIONE; PROTEIN KINASE C;

EID: 0031813589     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71010095.x     Document Type: Article
Times cited : (304)

References (74)
  • 1
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M., Dypbukt J. M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S. A., and Nicotera P. (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15, 961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 2
    • 0025250519 scopus 로고
    • Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells
    • Araki S., Simada Y., Kaji K., and Hayashi H. (1990) Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells. Biochem. Biophys. Res. Commun. 172, 1081-1085.
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 1081-1085
    • Araki, S.1    Simada, Y.2    Kaji, K.3    Hayashi, H.4
  • 3
    • 0029125857 scopus 로고
    • Aging, energy, and oxidative stress in neurodegenerative diseases
    • Beal M. F. (1995) Aging, energy, and oxidative stress in neurodegenerative diseases. Ann. Neurol. 38, 357-366.
    • (1995) Ann. Neurol. , vol.38 , pp. 357-366
    • Beal, M.F.1
  • 4
    • 0027787791 scopus 로고
    • Bcl-2 prevents killing of neuronal cells by glutamate but not by amyloid beta protein
    • Behl C., Hovey L., Krajewski S., Schubert D., and Reed J. C. (1993) Bcl-2 prevents killing of neuronal cells by glutamate but not by amyloid beta protein. Biochem. Biophys. Res. Commun. 197, 949-956.
    • (1993) Biochem. Biophys. Res. Commun. , vol.197 , pp. 949-956
    • Behl, C.1    Hovey, L.2    Krajewski, S.3    Schubert, D.4    Reed, J.C.5
  • 5
    • 0028207907 scopus 로고
    • Amyloid β peptide induces necrosis rather than apoptosis
    • Behl C., Davis J. B., Klier F. G., and Schubert D. (1994) Amyloid β peptide induces necrosis rather than apoptosis. Brain Res. 645, 253-264.
    • (1994) Brain Res. , vol.645 , pp. 253-264
    • Behl, C.1    Davis, J.B.2    Klier, F.G.3    Schubert, D.4
  • 7
    • 0015896004 scopus 로고
    • The inhibition of nucleic-acid binding proteins by aurintricarboxylic acid
    • Blumenthal T. and Landers T. A. (1973) The inhibition of nucleic-acid binding proteins by aurintricarboxylic acid. Biochem. Biophys. Res. Commun. 55, 680-688.
    • (1973) Biochem. Biophys. Res. Commun. , vol.55 , pp. 680-688
    • Blumenthal, T.1    Landers, T.A.2
  • 8
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/Superoxide in cortical cell cultures
    • Bonfoco E., Kraine D., Ankarcrona M., Nicotera P., and Lipton S. A. (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/Superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. USA 92, 7162-7166.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7162-7166
    • Bonfoco, E.1    Kraine, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 10
    • 0029077393 scopus 로고
    • NMDA and kainate induce internucleosomal DNA cleavage associated with both apoptotic and necrotic cell death in the neonatal rat brain
    • Campagne M. L., Lucassen P. J., Vermeulen J. P., and Balazs R. (1995) NMDA and kainate induce internucleosomal DNA cleavage associated with both apoptotic and necrotic cell death in the neonatal rat brain. Eur. J. Neurosci. 7, 1627-1640.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1627-1640
    • Campagne, M.L.1    Lucassen, P.J.2    Vermeulen, J.P.3    Balazs, R.4
  • 11
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D. W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1, 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 12
    • 0025283961 scopus 로고
    • Developmental cell death: Morphological diversity and multiple mechanisms
    • Clarke P. G. H. (1990) Developmental cell death: morphological diversity and multiple mechanisms. Anat. Embryol. (Berl.) 181, 195-213.
    • (1990) Anat. Embryol. (Berl.) , vol.181 , pp. 195-213
    • Clarke, P.G.H.1
  • 14
    • 0029050456 scopus 로고
    • Cell death: Current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo
    • Columbano A. (1995) Cell death: current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo. J. Cell. Biochem. 58, 181-190.
    • (1995) J. Cell. Biochem. , vol.58 , pp. 181-190
    • Columbano, A.1
  • 15
    • 0024315565 scopus 로고
    • Viability measurements in mammalian cell systems
    • Cook J. A. and Mitchell J. B. (1989) Viability measurements in mammalian cell systems. Anal. Biochem. 179, 1-7.
    • (1989) Anal. Biochem. , vol.179 , pp. 1-7
    • Cook, J.A.1    Mitchell, J.B.2
  • 17
    • 0028232469 scopus 로고
    • Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line
    • Davis J. B. and Maher P. (1994) Protein kinase C activation inhibits glutamate-induced cytotoxicity in a neuronal cell line. Brain Res. 652, 169-173.
    • (1994) Brain Res. , vol.652 , pp. 169-173
    • Davis, J.B.1    Maher, P.2
  • 18
    • 0027215170 scopus 로고
    • Glutamate-induced neuronal death is not programmed cell death in cerebellar culture
    • Dessi F., Charriaut-Marlangue C., Khrestchatisky M., and Ben-Ari Y. (1993) Glutamate-induced neuronal death is not programmed cell death in cerebellar culture. J. Neurochem. 60, 1953-1955.
    • (1993) J. Neurochem. , vol.60 , pp. 1953-1955
    • Dessi, F.1    Charriaut-Marlangue, C.2    Khrestchatisky, M.3    Ben-Ari, Y.4
  • 19
    • 0025002717 scopus 로고
    • Lack of excitotoxic cell death in serum-free cultures of rat cerebral cortex
    • Erdo S. L., Michler A., Wolff J. R., and Tytko H. (1990) Lack of excitotoxic cell death in serum-free cultures of rat cerebral cortex. Brain Res. 526, 328-332.
    • (1990) Brain Res. , vol.526 , pp. 328-332
    • Erdo, S.L.1    Michler, A.2    Wolff, J.R.3    Tytko, H.4
  • 20
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden A. I., Demediuk P., Panter S. S., and Vink R. (1989) The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244, 798-800.
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 21
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch S. M. and Francis H. (1994) Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124, 619-626.
    • (1994) J. Cell Biol. , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 22
    • 0028206292 scopus 로고
    • Cytotoxic effects of glutamic acid on PC12 cells
    • Froissard P. and Duval D. (1994) Cytotoxic effects of glutamic acid on PC12 cells. Neurochem. Int. 24, 485-493.
    • (1994) Neurochem. Int. , vol.24 , pp. 485-493
    • Froissard, P.1    Duval, D.2
  • 23
    • 0030927533 scopus 로고    scopus 로고
    • Role of glutathione metabolism in the glutamate-induced programmed cell death of neuronal-like PC12 cells
    • Froissard P., Monrocq H., and Duval D. (1997) Role of glutathione metabolism in the glutamate-induced programmed cell death of neuronal-like PC12 cells. Eur. J. Pharmacol. 326, 93-99.
    • (1997) Eur. J. Pharmacol. , vol.326 , pp. 93-99
    • Froissard, P.1    Monrocq, H.2    Duval, D.3
  • 24
    • 0022508122 scopus 로고
    • Amino acid neurotoxicity: Relationship to neuronal depolarisation in rat cerebellar slices
    • Garthwaite J., Garthwaite G., and Hajos F. (1986) Amino acid neurotoxicity: relationship to neuronal depolarisation in rat cerebellar slices. Neuroscience 18, 449-460.
    • (1986) Neuroscience , vol.18 , pp. 449-460
    • Garthwaite, J.1    Garthwaite, G.2    Hajos, F.3
  • 25
    • 0026689242 scopus 로고
    • Apoptosis: A different type of cell death
    • Gerschenson L. E. and Rotello R. J. (1992) Apoptosis: a different type of cell death. FASEB J. 6, 2450-2455.
    • (1992) FASEB J. , vol.6 , pp. 2450-2455
    • Gerschenson, L.E.1    Rotello, R.J.2
  • 27
    • 0028940994 scopus 로고
    • Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate
    • Greene J. G. and Greenamyre J. T. (1995) Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate. J. Neurochem. 64, 2332-2338.
    • (1995) J. Neurochem. , vol.64 , pp. 2332-2338
    • Greene, J.G.1    Greenamyre, J.T.2
  • 29
    • 0029048295 scopus 로고
    • Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro
    • Gwag B. J., Lobner D., Koh J. Y., Wie M. B., and Choi D. W. (1995) Blockade of glutamate receptors unmasks neuronal apoptosis after oxygen-glucose deprivation in vitro. Neuroscience 68, 615-619.
    • (1995) Neuroscience , vol.68 , pp. 615-619
    • Gwag, B.J.1    Lobner, D.2    Koh, J.Y.3    Wie, M.B.4    Choi, D.W.5
  • 30
    • 0029763211 scopus 로고    scopus 로고
    • DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease
    • Han Z., Malik N., Carter T., Reeves W. H., Wyche J. H., and Hendrickson E. A. (1996) DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease. J. Biol. Chem. 271, 25035-25040.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25035-25040
    • Han, Z.1    Malik, N.2    Carter, T.3    Reeves, W.H.4    Wyche, J.H.5    Hendrickson, E.A.6
  • 31
    • 0024595042 scopus 로고
    • Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
    • Hansen M. B., Nielsen S. E., and Berg K. (1989) Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol. Methods 119, 203-210.
    • (1989) J. Immunol. Methods , vol.119 , pp. 203-210
    • Hansen, M.B.1    Nielsen, S.E.2    Berg, K.3
  • 32
    • 0026009737 scopus 로고
    • Nerve cell death induced by kainic acid and quinolinic acid does not involve apoptosis
    • Ignatowicz E., Vezzani A.-M., Rizzi M., and D'Incalci M. (1991) Nerve cell death induced by kainic acid and quinolinic acid does not involve apoptosis. Neuroreport 2, 651-654.
    • (1991) Neuroreport , vol.2 , pp. 651-654
    • Ignatowicz, E.1    Vezzani, A.-M.2    Rizzi, M.3    D'Incalci, M.4
  • 33
    • 0028878716 scopus 로고
    • Expression of bcl-2 inhibits necrotic neural cell death
    • Kane D. J., Ord T., Anton R., and Bredesen D. E. (1995) Expression of bcl-2 inhibits necrotic neural cell death. J. Neurosci. Res. 40, 269-275.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 269-275
    • Kane, D.J.1    Ord, T.2    Anton, R.3    Bredesen, D.E.4
  • 34
    • 0021363552 scopus 로고
    • Epidermal growth factor and tumor promoters prevent DNA fragmentation by different mechanisms
    • Kanter P., Leister K. J., Tomei L. D., Wenner P. A., and Wenner C. E. (1984) Epidermal growth factor and tumor promoters prevent DNA fragmentation by different mechanisms. Biochem. Biophys. Res. Commun. 118, 392-399.
    • (1984) Biochem. Biophys. Res. Commun. , vol.118 , pp. 392-399
    • Kanter, P.1    Leister, K.J.2    Tomei, L.D.3    Wenner, P.A.4    Wenner, C.E.5
  • 36
    • 77956801270 scopus 로고
    • Anatomical methods in cell death
    • (Schwartz L. M. and Osborne B. A., eds), Academic Press, San Diego
    • Kerr J. F. R., Gobe G. C., Winterford C. M., and Harmon B. V. (1995) Anatomical methods in cell death, in Cell Death (Schwartz L. M. and Osborne B. A., eds), pp. 1-26. Academic Press, San Diego.
    • (1995) Cell Death , pp. 1-26
    • Kerr, J.F.R.1    Gobe, G.C.2    Winterford, C.M.3    Harmon, B.V.4
  • 38
    • 0029069295 scopus 로고
    • ICE-like proteases in apoptosis
    • Kumar S. (1995) ICE-like proteases in apoptosis. Trends Biochem. Sci. 20, 198-202.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 198-202
    • Kumar, S.1
  • 40
    • 0027252546 scopus 로고
    • Contributory mechanisms in the causation of neurodegenerative diseases
    • Lees G. J. (1993) Contributory mechanisms in the causation of neurodegenerative diseases. Neuroscience 54, 287-322.
    • (1993) Neuroscience , vol.54 , pp. 287-322
    • Lees, G.J.1
  • 41
    • 0030867994 scopus 로고    scopus 로고
    • A role of 12-lipoxygenase in nerve cell death caused by glutathione depletion
    • Li Y., Maher P., and Schubert D. (1997) A role of 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 19, 453-463.
    • (1997) Neuron , vol.19 , pp. 453-463
    • Li, Y.1    Maher, P.2    Schubert, D.3
  • 42
    • 0029844831 scopus 로고    scopus 로고
    • The role of monoamine metabolism in oxidative glutamate toxicity
    • Maher P. and Davis J. B. (1996) The role of monoamine metabolism in oxidative glutamate toxicity. Neuroscience 16, 6394-6401.
    • (1996) Neuroscience , vol.16 , pp. 6394-6401
    • Maher, P.1    Davis, J.B.2
  • 43
    • 1842376234 scopus 로고    scopus 로고
    • Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin
    • Mansat V., Bettaieb A., Levade T., Laurent G., and Jaffrezou J. P. (1997) Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. FASEB J. 11, 695-702.
    • (1997) FASEB J. , vol.11 , pp. 695-702
    • Mansat, V.1    Bettaieb, A.2    Levade, T.3    Laurent, G.4    Jaffrezou, J.P.5
  • 44
    • 0027411586 scopus 로고
    • Apoptosis: Suicide, murder or execution?
    • Martin S. J. (1993). Apoptosis: suicide, murder or execution? Trends Cell Biol. 3, 141-144.
    • (1993) Trends Cell Biol. , vol.3 , pp. 141-144
    • Martin, S.J.1
  • 45
    • 0024402595 scopus 로고
    • Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C
    • McConkey D. J., Hartzell P., Jondal M., and Orrenius S. (1989) Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C. J. Biol. Chem. 264, 13399-13402.
    • (1989) J. Biol. Chem. , vol.264 , pp. 13399-13402
    • McConkey, D.J.1    Hartzell, P.2    Jondal, M.3    Orrenius, S.4
  • 46
    • 0029199452 scopus 로고
    • The end of the (cell) line: Methods for the study of apoptosis in vitro
    • (Schwartz L. M. and Osborne B. A., eds), Academic Press, San Diego
    • McGahon A. J., Martin S. J., Bissonnette R. P., Mahboubi A., Shi Y., Mogil R. J., Nishioka W. K., and Green D. R. (1995) The end of the (cell) line: methods for the study of apoptosis in vitro, in Cell Death (Schwartz L. M. and Osborne B. A., eds), pp. 153-185. Academic Press, San Diego.
    • (1995) Cell Death , pp. 153-185
    • McGahon, A.J.1    Martin, S.J.2    Bissonnette, R.P.3    Mahboubi, A.4    Shi, Y.5    Mogil, R.J.6    Nishioka, W.K.7    Green, D.R.8
  • 47
    • 0027071804 scopus 로고
    • Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
    • Mesner P. W., Winters T. R., and Green S. H, (1992) Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons. J. Cell Biol. 119, 1669-1680.
    • (1992) J. Cell Biol. , vol.119 , pp. 1669-1680
    • Mesner, P.W.1    Winters, T.R.2    Green, S.H.3
  • 48
    • 0024446419 scopus 로고
    • Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line
    • Miyamoto M., Murphy T. H., Schnaar R. L., and Coyle J. T. (1989) Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line. J. Pharmacol. Exp. Ther. 250, 1132-1140.
    • (1989) J. Pharmacol. Exp. Ther. , vol.250 , pp. 1132-1140
    • Miyamoto, M.1    Murphy, T.H.2    Schnaar, R.L.3    Coyle, J.T.4
  • 49
    • 0025688292 scopus 로고
    • Induction and expression of long and short term neurosecretory potentiation in a neural cell line
    • Morimoto B. H. and Koshland D. E. (1990) Induction and expression of long and short term neurosecretory potentiation in a neural cell line. Neuron 5, 875-880.
    • (1990) Neuron , vol.5 , pp. 875-880
    • Morimoto, B.H.1    Koshland, D.E.2
  • 50
    • 0029738086 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
    • Morris E. J. and Geller H. M. (1996) Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity. J. Cell Biol. 134, 757-770.
    • (1996) J. Cell Biol. , vol.134 , pp. 757-770
    • Morris, E.J.1    Geller, H.M.2
  • 51
    • 0023833551 scopus 로고
    • Calcium-dependent glutamate cytotoxicity in a neuronal cell line
    • Murphy T. H., Malouf A. T., Sastre A., Schnaar R. L., and Coyle J. T. (1988) Calcium-dependent glutamate cytotoxicity in a neuronal cell line. Brain Res. 444, 325-332.
    • (1988) Brain Res. , vol.444 , pp. 325-332
    • Murphy, T.H.1    Malouf, A.T.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 52
    • 0024678458 scopus 로고
    • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • Murphy T. H., Miyamoto M., Sastre A., Schnaar R. L., and Coyle J. T. (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2, 1547-1558.
    • (1989) Neuron , vol.2 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 53
    • 0025355933 scopus 로고
    • Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake
    • Murphy T. H., Schnaar R. L., and Coyle J. T. (1990) Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake. FASEB J. 4, 1624-1633.
    • (1990) FASEB J. , vol.4 , pp. 1624-1633
    • Murphy, T.H.1    Schnaar, R.L.2    Coyle, J.T.3
  • 54
    • 0028804835 scopus 로고
    • Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures
    • Newell D. W., Barth A., Papermaster V., and Malouf A. T. (1995) Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. J. Neurosci. 15, 7702-7711.
    • (1995) J. Neurosci. , vol.15 , pp. 7702-7711
    • Newell, D.W.1    Barth, A.2    Papermaster, V.3    Malouf, A.T.4
  • 55
    • 0029670265 scopus 로고    scopus 로고
    • ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis
    • Nicholson D. W. (1996) ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis. Nat. Biotechnol. 14, 297-301.
    • (1996) Nat. Biotechnol. , vol.14 , pp. 297-301
    • Nicholson, D.W.1
  • 57
    • 0027468201 scopus 로고
    • Vulnerability of oligodendroglia to glutamate: Pharmacology, mechanisms and prevention
    • Oka A., Belliveau M. J., Rosenberg P. A., and Volpe J. J. (1993) Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms and prevention. J. Neurosci. 13, 1441-1453.
    • (1993) J. Neurosci. , vol.13 , pp. 1441-1453
    • Oka, A.1    Belliveau, M.J.2    Rosenberg, P.A.3    Volpe, J.J.4
  • 58
    • 0029066460 scopus 로고
    • A neuroprotective compound, aurin tricarboxylic acid, stimulates the tyrosine phosphorylation cascade in PC12 cells
    • Okada N. and Koizumi S. (1995) A neuroprotective compound, aurin tricarboxylic acid, stimulates the tyrosine phosphorylation cascade in PC12 cells. J. Biol. Chem. 270, 16464-16469.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16464-16469
    • Okada, N.1    Koizumi, S.2
  • 59
    • 0029927422 scopus 로고    scopus 로고
    • The role of proteases during apoptosis
    • Patel T., Gores G. J., and Kaufmann S. H. (1996) The role of proteases during apoptosis. FASEB J. 10, 587-597.
    • (1996) FASEB J. , vol.10 , pp. 587-597
    • Patel, T.1    Gores, G.J.2    Kaufmann, S.H.3
  • 61
    • 0028246870 scopus 로고
    • Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione
    • Ratan R., Murphy T. H., and Baraban J. M. (1994) Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J. Neurosci. 14, 4385-4392.
    • (1994) J. Neurosci. , vol.14 , pp. 4385-4392
    • Ratan, R.1    Murphy, T.H.2    Baraban, J.M.3
  • 62
  • 64
    • 0029954311 scopus 로고    scopus 로고
    • Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
    • Schulz J. B., Weller M., and Klockgether T. (1996) Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J. Neurosci. 16, 4696-4706.
    • (1996) J. Neurosci. , vol.16 , pp. 4696-4706
    • Schulz, J.B.1    Weller, M.2    Klockgether, T.3
  • 66
    • 0028586834 scopus 로고
    • Cycloheximide and actinomycin D block the toxic effect of glutamic acid on PC12 cells
    • Serghini R., Froissard P., Sola B., and Duval D. (1994) Cycloheximide and actinomycin D block the toxic effect of glutamic acid on PC12 cells. Neuroreport 6, 29-32.
    • (1994) Neuroreport , vol.6 , pp. 29-32
    • Serghini, R.1    Froissard, P.2    Sola, B.3    Duval, D.4
  • 67
    • 0029891535 scopus 로고    scopus 로고
    • Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: Possible involvement of common mediators in apoptotic and necrotic signal transductions
    • Shimizu S., Eguchi Y., Kamiike W., Waguri S., Uchiyama Y., Matsuda H., and Tsujimoto Y. (1996) Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions. Oncogene 12, 2045-2050.
    • (1996) Oncogene , vol.12 , pp. 2045-2050
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Waguri, S.4    Uchiyama, Y.5    Matsuda, H.6    Tsujimoto, Y.7
  • 68
    • 0019842691 scopus 로고
    • Cell damage in the brain: A speculative hypothesis
    • Siesjö B. K. (1981) Cell damage in the brain: a speculative hypothesis. J. Cereb. Blood Flow Metab. 1, 155-185.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 155-185
    • Siesjö, B.K.1
  • 69
    • 0025677250 scopus 로고
    • Intracellular thiols regulate activation of nuclear factor kB and transcription of human immunodeficiency virus
    • Staal F. J. T., Roederer M., and Herzenberg L. A. (1990) Intracellular thiols regulate activation of nuclear factor kB and transcription of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 87, 9943-9947.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9943-9947
    • Staal, F.J.T.1    Roederer, M.2    Herzenberg, L.A.3
  • 70
    • 0025970107 scopus 로고
    • Glutamate neurotoxicity and the inhibition of protein synthesis in the hippocampal slice
    • Vornov J. J. and Coyle J. T. (1991) Glutamate neurotoxicity and the inhibition of protein synthesis in the hippocampal slice, J. Neurochem. 56, 996-1006.
    • (1991) J. Neurochem. , vol.56 , pp. 996-1006
    • Vornov, J.J.1    Coyle, J.T.2
  • 71
    • 0027658225 scopus 로고
    • Role of proteolysis in apoptosis: Involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes
    • Weaver V. M., Lach B., Walker P. R., and Sikorska M. (1993) Role of proteolysis in apoptosis: involvement of serine proteases in internucleosomal DNA fragmentation in immature thymocytes. Biochem. Cell. Biol. 71, 488-500.
    • (1993) Biochem. Cell. Biol. , vol.71 , pp. 488-500
    • Weaver, V.M.1    Lach, B.2    Walker, P.R.3    Sikorska, M.4
  • 72
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z., Kickens M., Raingeaud J., Davis R. J., and Greenberg M. E. (1995) Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Kickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 73
    • 0029157932 scopus 로고
    • Excitotoxicity at both NMDA and non-NMDA glutamate receptors is antagonized by aurintricarboxylic acid: Evidence for differing mechanisms of action
    • Zeevalk G. D., Schoepp D., and Nicklas W. J. (1995) Excitotoxicity at both NMDA and non-NMDA glutamate receptors is antagonized by aurintricarboxylic acid: evidence for differing mechanisms of action. J. Neurochem. 64, 1749-1758.
    • (1995) J. Neurochem. , vol.64 , pp. 1749-1758
    • Zeevalk, G.D.1    Schoepp, D.2    Nicklas, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.