Synthesis of 2-acetamido-1,2-dideoxy-d-galacto-nojirimycin [DGJNAc] from d-glucuronolactone: the first sub-micromolar inhibitor of α-N-acetylgalactosaminidases

Tetrahedron Letters

Volumn 51, Issue 17, 2010, Pages 2222-2224

  Best, Daniel ^a   Chairatana, Phoom ^a   Glawar, Andreas F G ^a,b   Crabtree, Elizabeth ^a,b   Butters, Terry D ^b   Wilson, Francis X ^e   Yu, Chu Yi ^d   Wang, Wu Bao ^d   Jia, Yue Mei ^d   Adachi, Isao ^c   Kato, Atsushi ^c   Fleet, George W J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF TOYAMA   (Japan)

^d INSTITUTE OF CHEMISTRY   (China)

^e SUMMIT PLC   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 ACETAMIDO 1,2 DIDEOXY GALACTO NOJIRIMYCIN; ALPHA N ACETYLGALACTOSAMINIDASE; BETA N ACETYLHEXOSAMINIDASE; GLUCURONOLACTONE; NOJIRIMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; ENANTIOMER; ENZYME INHIBITION; SYNTHESIS;

CHARONIA;

EID: 77949568804     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.02.063     Document Type: Article

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