Looking glass inhibitors: both enantiomeric N-benzyl derivatives of 1,4-dideoxy-1,4-imino-d-lyxitol [a potent competitive inhibitor of α-d-galactosidase] and of 1,4-dideoxy-1,4-imino-l-lyxitol [a weak competitive inhibitor of α-d-galactosidase] inhibit naringinase, an α-l-rhamnosidase competitively

Tetrahedron Asymmetry

Volumn 20, Issue 20, 2009, Pages 2368-2373

  Mercer, Thomas B ^a   Jenkinson, Sarah F ^a   Bartholomew, Barbara ^b   Nash, Robert J ^b   Miyauchi, Saori ^c   Kato, Atsushi ^c   Fleet, George W J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Phytoquest Limited   (United Kingdom)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIDEOXY 1,4 IMINO DEXTRO LYXITOL N BENZYL DERIVATIVE; 1,4 DIDEOXY 1,4 IMINO LEVO LYXITOL N BENZYL DERIVATIVE; ACETONITRILE DERIVATIVE; ALCOHOL; ALPHA GALACTOSIDASE; ALPHA LEVO RHAMNOSIDASE; BENZHYDRYL DERIVATIVE; BENZYL DERIVATIVE; DIAZOMETHANE; ENZYME; IMINOSUGAR; LACTONE DERIVATIVE; NARINGINASE; RHAMNOSE; RIBONOLACTONE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; COMPETITIVE INHIBITION; DRUG SYNTHESIS; ENANTIOMER; ENZYME INHIBITION; PRIORITY JOURNAL;

EID: 72149116465     PISSN: 09574166     EISSN: 1362511X     Source Type: Journal    
DOI: 10.1016/j.tetasy.2009.10.004     Document Type: Article

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