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Volumn 191, Issue 5, 2005, Pages 694-701

T cell activation in HIV-seropositive Ugandans: Differential associations with viral load, CD4+ T cell depletion, and coinfection

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; HLA DR ANTIGEN;

EID: 13944252473     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/427516     Document Type: Article
Times cited : (82)

References (47)
  • 1
    • 0036534655 scopus 로고    scopus 로고
    • Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infection
    • Giorgi JV, Lyles RH, Matud JL, et al. Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infection. J Acquir Immune Defic Syndr 2002; 29:346-05.
    • (2002) J Acquir Immune Defic Syndr , vol.29 , pp. 346-305
    • Giorgi, J.V.1    Lyles, R.H.2    Matud, J.L.3
  • 2
    • 0037105617 scopus 로고    scopus 로고
    • CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load
    • Sousa AE, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino RM. CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load. J Immunol 2002; 169:3400-6.
    • (2002) J Immunol , vol.169 , pp. 3400-3406
    • Sousa, A.E.1    Carneiro, J.2    Meier-Schellersheim, M.3    Grossman, Z.4    Victorino, R.M.5
  • 3
    • 0041327667 scopus 로고    scopus 로고
    • Persistent immune activation in HIV-1 infection is associated with progression to AIDS
    • Hazenberg MD, Otto SA, van Benthem BH, et al. Persistent immune activation in HIV-1 infection is associated with progression to AIDS. AIDS 2003; 17:1881-8.
    • (2003) AIDS , vol.17 , pp. 1881-1888
    • Hazenberg, M.D.1    Otto, S.A.2    Van Benthem, B.H.3
  • 4
    • 0032955651 scopus 로고    scopus 로고
    • Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage
    • Giorgi JV, Hultin LE, McKeating JA, et al. Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis 1999; 179:859-70.
    • (1999) J Infect Dis , vol.179 , pp. 859-870
    • Giorgi, J.V.1    Hultin, L.E.2    McKeating, J.A.3
  • 5
    • 0032512268 scopus 로고    scopus 로고
    • Expression of CD38 on CD8 T cells predicts maintenance of high viraemia in HAART-treated HIV-1-infected children. Highly active antiretroviral therapy
    • Vigano A, Saresella M, Rusconi S, Ferrante P, Clerici M. Expression of CD38 on CD8 T cells predicts maintenance of high viraemia in HAART-treated HIV-1-infected children. Highly active antiretroviral therapy. Lancet 1998; 352:1905-6.
    • (1998) Lancet , vol.352 , pp. 1905-1906
    • Vigano, A.1    Saresella, M.2    Rusconi, S.3    Ferrante, P.4    Clerici, M.5
  • 6
    • 0041326880 scopus 로고    scopus 로고
    • Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy
    • Hunt PW, Deeks SG, Rodriguez B, et al. Continued CD4 cell count increases in HIV-infected adults experiencing 4 years of viral suppression on antiretroviral therapy. AIDS 2003; 17:1907-15.
    • (2003) AIDS , vol.17 , pp. 1907-1915
    • Hunt, P.W.1    Deeks, S.G.2    Rodriguez, B.3
  • 8
    • 0023694580 scopus 로고
    • AIDS as immune system activation: A model for pathogenesis
    • Ascher MS, Sheppard HW. AIDS as immune system activation: a model for pathogenesis. Clin Exp Immunol 1988; 73:165-7.
    • (1988) Clin Exp Immunol , vol.73 , pp. 165-167
    • Ascher, M.S.1    Sheppard, H.W.2
  • 9
    • 0032568603 scopus 로고    scopus 로고
    • Multiple modes of cellular activation and virus transmission in HIV infection: A role for chronically and latently infected cells in sustaining viral replication
    • Grossman ZM, Feinberg B, Paul WE. Multiple modes of cellular activation and virus transmission in HIV infection: a role for chronically and latently infected cells in sustaining viral replication. Proc Natl Acad Sci USA 1998; 95:6314-9.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6314-6319
    • Grossman, Z.M.1    Feinberg, B.2    Paul, W.E.3
  • 10
    • 0033624622 scopus 로고    scopus 로고
    • The impact of HIV on naive T-cell homeostasis
    • Grossman Z, Paul WE. The impact of HIV on naive T-cell homeostasis. Nat Med 2000; 6:976-7.
    • (2000) Nat Med , vol.6 , pp. 976-977
    • Grossman, Z.1    Paul, W.E.2
  • 13
    • 0032032504 scopus 로고    scopus 로고
    • Direct HIV cytopathicity cannot account for CD4 decline in AIDS in the presence of homeostasis: A worst-case dynamic analysis
    • Anderson RW, Ascher MS, Sheppard HW. Direct HIV cytopathicity cannot account for CD4 decline in AIDS in the presence of homeostasis: a worst-case dynamic analysis. J Acquir Immune Defic Syndr Hum Retrovirol 1998; 17:245-52.
    • (1998) J Acquir Immune Defic Syndr Hum Retrovirol , vol.17 , pp. 245-252
    • Anderson, R.W.1    Ascher, M.S.2    Sheppard, H.W.3
  • 14
    • 0034765697 scopus 로고    scopus 로고
    • Distribution of lymphocyte subsets in healthy human immunodeficiency virus-negative adult Ethiopians from two geographic locales
    • Kassu A, Tsegaye A, Petros B, et al. Distribution of lymphocyte subsets in healthy human immunodeficiency virus-negative adult Ethiopians from two geographic locales. Clin Diagn Lab Immunol 2001; 8:1171-6.
    • (2001) Clin Diagn Lab Immunol , vol.8 , pp. 1171-1176
    • Kassu, A.1    Tsegaye, A.2    Petros, B.3
  • 15
    • 0034882135 scopus 로고    scopus 로고
    • Helminths, human immunodeficiency virus and tuberculosis
    • Borkow G, Weisman Z, Leng Q, et al. Helminths, human immunodeficiency virus and tuberculosis. Scand J Infect Dis 2001; 33:568-71.
    • (2001) Scand J Infect Dis , vol.33 , pp. 568-571
    • Borkow, G.1    Weisman, Z.2    Leng, Q.3
  • 16
    • 0030025111 scopus 로고    scopus 로고
    • Immune dysregulation in Ethiopian immigrants in Israel: Relevance to helminth infections?
    • Bentwich Z, Weisman Z, Moroz C, Bar-Yehuda S, Kalinkovich A. Immune dysregulation in Ethiopian immigrants in Israel: relevance to helminth infections? Clin Exp Immunol 1996; 103:239-43.
    • (1996) Clin Exp Immunol , vol.103 , pp. 239-243
    • Bentwich, Z.1    Weisman, Z.2    Moroz, C.3    Bar-Yehuda, S.4    Kalinkovich, A.5
  • 17
    • 0033791524 scopus 로고    scopus 로고
    • Immune activation in Africa is environmentally-driven and is associated with upregulation of CCR5
    • Italian-Ugandan AIDS Project
    • Clerici M, Butto S, Lukwiya M, et al. Immune activation in Africa is environmentally-driven and is associated with upregulation of CCR5. Italian-Ugandan AIDS Project. AIDS 2000; 14:2083-92.
    • (2000) AIDS , vol.14 , pp. 2083-2092
    • Clerici, M.1    Butto, S.2    Lukwiya, M.3
  • 18
    • 0346656812 scopus 로고    scopus 로고
    • AIDS in Africa: The impact of coinfections on the pathogenesis of HIV-1 infection
    • Lawn SD. AIDS in Africa: the impact of coinfections on the pathogenesis of HIV-1 infection. J Infect 2004;48:1-12.
    • (2004) J Infect , vol.48 , pp. 1-12
    • Lawn, S.D.1
  • 19
    • 0347758636 scopus 로고    scopus 로고
    • Population-based hematologic and immunologic reference values for a healthy Ugandan population
    • Lugada ES, Mermin J, Kaharuza F, et al. Population-based hematologic and immunologic reference values for a healthy Ugandan population. Clin Diagn Lab Immunol 2004; 11:29-34.
    • (2004) Clin Diagn Lab Immunol , vol.11 , pp. 29-34
    • Lugada, E.S.1    Mermin, J.2    Kaharuza, F.3
  • 20
    • 0031751647 scopus 로고    scopus 로고
    • + T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection
    • + T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection. J Infect Dis 1998; 178:I279-87.
    • (1998) J Infect Dis , vol.178
    • Orendi, J.M.1    Bloern, A.C.2    Borleffs, J.C.3
  • 22
    • 0030668834 scopus 로고    scopus 로고
    • Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression
    • Liu Z, Cumberland WG, Hultin LE, Prince HE, Detels R, Giorgi JV. Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquir Immune Defic Syndr Hum Retrovirol 1997; 16:83-92.
    • (1997) J Acquir Immune Defic Syndr Hum Retrovirol , vol.16 , pp. 83-92
    • Liu, Z.1    Cumberland, W.G.2    Hultin, L.E.3    Prince, H.E.4    Detels, R.5    Giorgi, J.V.6
  • 23
    • 0035676515 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy responders exhibit a phenotypic lymphocyte pattern comparable to that of long-term nonprogressors
    • Knapp S, Lenz P, Gerlitz S, Rieger A, Meier X, Stingl G. Highly active antiretroviral therapy responders exhibit a phenotypic lymphocyte pattern comparable to that of long-term nonprogressors. Int Arch Allergy Immunol 2001; 126:248-56.
    • (2001) Int Arch Allergy Immunol , vol.126 , pp. 248-256
    • Knapp, S.1    Lenz, P.2    Gerlitz, S.3    Rieger, A.4    Meier, X.5    Stingl, G.6
  • 24
    • 0032762069 scopus 로고    scopus 로고
    • Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection
    • Dyrhol-Riise AM, Voltersvik P, Olofsson J, Asjo B. Activation of CD8 T cells normalizes and correlates with the level of infectious provirus in tonsils during highly active antiretroviral therapy in early HIV-1 infection. AIDS 1999; 13:2365-76.
    • (1999) AIDS , vol.13 , pp. 2365-2376
    • Dyrhol-Riise, A.M.1    Voltersvik, P.2    Olofsson, J.3    Asjo, B.4
  • 25
    • 0036932579 scopus 로고    scopus 로고
    • Immune activation in patients infected with HIV type 1 and maintaining suppression of viral replication by highly active antiretroviral therapy
    • Almeida CA, Price P, French MA. Immune activation in patients infected with HIV type 1 and maintaining suppression of viral replication by highly active antiretroviral therapy. AIDS Res Hum Retroviruses 2002; 18:1351-5.
    • (2002) AIDS Res Hum Retroviruses , vol.18 , pp. 1351-1355
    • Almeida, C.A.1    Price, P.2    French, M.A.3
  • 26
    • 0035423912 scopus 로고    scopus 로고
    • Immune activation correlates better than HIV plasma viral load with CD4 T-cell decline during HIV infection
    • Leng Q, Borkow G, Weisman Z, Stein M, Kalinkovich A, Bentwich Z. Immune activation correlates better than HIV plasma viral load with CD4 T-cell decline during HIV infection. J Acquir Immune Defic Syndr 2001; 27:389-97.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 389-397
    • Leng, Q.1    Borkow, G.2    Weisman, Z.3    Stein, M.4    Kalinkovich, A.5    Bentwich, Z.6
  • 27
    • 0037388893 scopus 로고    scopus 로고
    • + T cell subsets and activation status in HIV-1 infected and uninfected adult Ethiopians
    • + T cell subsets and activation status in HIV-1 infected and uninfected adult Ethiopians. Clin Exp Immunol 2003; 132:113-9.
    • (2003) Clin Exp Immunol , vol.132 , pp. 113-119
    • Kassu, A.1    Tsegaye, A.2    Wolday, D.3
  • 28
    • 0030060368 scopus 로고    scopus 로고
    • Immunophenotypic and molecular analyses of acquired immune deficiency syndrome-related and Epstein-Barr virus-associated lymphomas: A comparative study
    • Carbone A, Dolcetti R, Gloghini A, et al. Immunophenotypic and molecular analyses of acquired immune deficiency syndrome-related and Epstein-Barr virus-associated lymphomas: a comparative study. Hum Pathol 1996; 27:133-46.
    • (1996) Hum Pathol , vol.27 , pp. 133-146
    • Carbone, A.1    Dolcetti, R.2    Gloghini, A.3
  • 29
    • 0032564581 scopus 로고    scopus 로고
    • Immune activation in HIV-infected African individuals
    • Rizzardini G, Trabattoni D, Saresella M, et al. Immune activation in HIV-infected African individuals. AIDS 1998; 12:2387-96.
    • (1998) AIDS , vol.12 , pp. 2387-2396
    • Rizzardini, G.1    Trabattoni, D.2    Saresella, M.3
  • 30
    • 0028904083 scopus 로고
    • Immune activation is a dominant factor in the pathogenesis of African AIDS
    • Bentwich Z, Kalinkovich A, Weisman Z. Immune activation is a dominant factor in the pathogenesis of African AIDS. Immunol Today 1995; 16:187-91.
    • (1995) Immunol Today , vol.16 , pp. 187-191
    • Bentwich, Z.1    Kalinkovich, A.2    Weisman, Z.3
  • 31
    • 9144252521 scopus 로고    scopus 로고
    • Immunophenotyping of blood lymphocytes at birth, during childhood, and during adulthood in HIV-1-uninfected Ethiopians
    • Tsegaye A, Wolday D, Otto S, et al. Immunophenotyping of blood lymphocytes at birth, during childhood, and during adulthood in HIV-1-uninfected Ethiopians. Clin Immunol 2003; 109:338-46.
    • (2003) Clin Immunol , vol.109 , pp. 338-346
    • Tsegaye, A.1    Wolday, D.2    Otto, S.3
  • 32
    • 0028246838 scopus 로고
    • Selective increase of activation antigens HLA-DR and CD38 on CD4+ CD45RO+ T lymphocytes during HIV-1 infection
    • Kestens L, Vanham G, Vereecken C, et al. Selective increase of activation antigens HLA-DR and CD38 on CD4+ CD45RO+ T lymphocytes during HIV-1 infection. Clin Exp Immunol 1994; 95:436-41.
    • (1994) Clin Exp Immunol , vol.95 , pp. 436-441
    • Kestens, L.1    Vanham, G.2    Vereecken, C.3
  • 33
    • 0032511914 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study
    • Bisset LR, Cone RW, Huber W, et al. Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study. AIDS 1998; 12:2115-23.
    • (1998) AIDS , vol.12 , pp. 2115-2123
    • Bisset, L.R.1    Cone, R.W.2    Huber, W.3
  • 34
    • 0032550369 scopus 로고    scopus 로고
    • + T lymphocytes in HIV-1 infection as measured by Ki-67 antigen
    • + T lymphocytes in HIV-1 infection as measured by Ki-67 antigen. J Exp Med 1998; 187:1295-303.
    • (1998) J Exp Med , vol.187 , pp. 1295-1303
    • Sachsenberg, N.1    Perelson, A.S.2    Yerly, S.3
  • 35
    • 0343920019 scopus 로고    scopus 로고
    • T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: A longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART)
    • Hazenberg MD, Stuart JW, Otto SA, et al. T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART). Blood 2000; 95:249-55.
    • (2000) Blood , vol.95 , pp. 249-255
    • Hazenberg, M.D.1    Stuart, J.W.2    Otto, S.A.3
  • 36
    • 0031662093 scopus 로고    scopus 로고
    • Effect of immune activation on the dynamics of human immunodeficiency virus replication and on the distribution of viral quasispecies
    • Ostrowski MA, Krakauer DC, Li Y, et al. Effect of immune activation on the dynamics of human immunodeficiency virus replication and on the distribution of viral quasispecies. J Virol 1998; 72:7772-84.
    • (1998) J Virol , vol.72 , pp. 7772-7784
    • Ostrowski, M.A.1    Krakauer, D.C.2    Li, Y.3
  • 37
    • 0030209725 scopus 로고    scopus 로고
    • Effect of Mycobacterium tuberculosis on HIV replication: Role of immune activation
    • Goletti D, Weissman D, Jackson RW, et al. Effect of Mycobacterium tuberculosis on HIV replication: role of immune activation. J Immunol 1996; 157:1271-8.
    • (1996) J Immunol , vol.157 , pp. 1271-1278
    • Goletti, D.1    Weissman, D.2    Jackson, R.W.3
  • 38
    • 0030153588 scopus 로고    scopus 로고
    • Immune response and AIDS
    • Stanley SK. Immune response and AIDS. TB HIV 1996; 11:12-3.
    • (1996) TB HIV , vol.11 , pp. 12-13
    • Stanley, S.K.1
  • 40
    • 0037562834 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1 RNA levels and CD4 lymphocyte counts, during treatment for active tuberculosis, in South African patients
    • Morris L, Martin DJ, Bredell H, et al. Human immunodeficiency virus-1 RNA levels and CD4 lymphocyte counts, during treatment for active tuberculosis, in South African patients. J Infect Dis 2003; 187:1967-71.
    • (2003) J Infect Dis , vol.187 , pp. 1967-1971
    • Morris, L.1    Martin, D.J.2    Bredell, H.3
  • 41
    • 0034534903 scopus 로고    scopus 로고
    • T cell activation, apoptosis and cytokine dysregulation in the (co)pathogenesis of HIV and pulmonary tuberculosis (TB)
    • Hertoghe T, Wajja A, Ntambi L, et al. T cell activation, apoptosis and cytokine dysregulation in the (co)pathogenesis of HIV and pulmonary tuberculosis (TB). Clin Exp Immunol 2000; 122:350-7.
    • (2000) Clin Exp Immunol , vol.122 , pp. 350-357
    • Hertoghe, T.1    Wajja, A.2    Ntambi, L.3
  • 42
    • 0031766130 scopus 로고    scopus 로고
    • The effect of acute infectious illnesses on plasma human immunodeficiency virus (HIV) type 1 load and the expression of serologic markers of immune activation among HIV-infected adults
    • Sulkowski MS, Chaisson RE, Karp CL, Moore RD, Margolick JB, Quinn TC. The effect of acute infectious illnesses on plasma human immunodeficiency virus (HIV) type 1 load and the expression of serologic markers of immune activation among HIV-infected adults. J Infect Dis 1998; 178:1642-8.
    • (1998) J Infect Dis , vol.178 , pp. 1642-1648
    • Sulkowski, M.S.1    Chaisson, R.E.2    Karp, C.L.3    Moore, R.D.4    Margolick, J.B.5    Quinn, T.C.6
  • 43
    • 0035341952 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1) plasma virus load and markers of immune activation among HIV-infected female sex workers with sexually transmitted diseases in Abidjan, Cote d'Ivoire
    • Nkengasong JN, Kestens L, Ghys PD, et al. Human immunodeficiency virus type 1 (HIV-1) plasma virus load and markers of immune activation among HIV-infected female sex workers with sexually transmitted diseases in Abidjan, Cote d'Ivoire. J Infect Dis 2001; 183:1405-8.
    • (2001) J Infect Dis , vol.183 , pp. 1405-1408
    • Nkengasong, J.N.1    Kestens, L.2    Ghys, P.D.3
  • 44
    • 0035407752 scopus 로고    scopus 로고
    • Lack of induction of interleukin-2-receptor-alpha in patients with tuberculosis and human immunodeficiency virus co-infection: Implications for pathogenesis
    • Lawn SD, Rudolph D, Ackah A, Coulibaly D, Wiktor S, Lal RB. Lack of induction of interleukin-2-receptor-alpha in patients with tuberculosis and human immunodeficiency virus co-infection: implications for pathogenesis. Trans R Soc Trop Med Hyg 2001; 95:449-52.
    • (2001) Trans R Soc Trop Med Hyg , vol.95 , pp. 449-452
    • Lawn, S.D.1    Rudolph, D.2    Ackah, A.3    Coulibaly, D.4    Wiktor, S.5    Lal, R.B.6
  • 45
    • 0042128344 scopus 로고    scopus 로고
    • Changes in levels of immune activation and reconstitution markers among HIV-1-infected Africans receiving antiretroviral therapy
    • Koblavi-Deme S, Maran M, Kabran N, et al. Changes in levels of immune activation and reconstitution markers among HIV-1-infected Africans receiving antiretroviral therapy. AIDS 2003; 17(Suppl 3):S17-22.
    • (2003) AIDS , vol.17 , Issue.SUPPL. 3
    • Koblavi-Deme, S.1    Maran, M.2    Kabran, N.3
  • 46
    • 0037169219 scopus 로고    scopus 로고
    • Inter- and intra-genic intersubtype HIV-1 recombination in rural and semi-urban Uganda
    • Yirrell DL, Kaleebu P, Morgan D, et al. Inter- and intra-genic intersubtype HIV-1 recombination in rural and semi-urban Uganda. AIDS 2002; 16:279-86.
    • (2002) AIDS , vol.16 , pp. 279-286
    • Yirrell, D.L.1    Kaleebu, P.2    Morgan, D.3
  • 47
    • 0033791350 scopus 로고    scopus 로고
    • Cellular immunity to human immunodeficiency virus type 1 (HIV-1) clades: Relevance to HIV-1 vaccine trials in Uganda
    • Cao H, Mani I, Vincent R, et al. Cellular immunity to human immunodeficiency virus type 1 (HIV-1) clades: relevance to HIV-1 vaccine trials in Uganda. J Infect Dis 2000; 182:1350-6.
    • (2000) J Infect Dis , vol.182 , pp. 1350-1356
    • Cao, H.1    Mani, I.2    Vincent, R.3


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