Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 7, 2010, Pages 2229-2233

  Cohen, Frederick ^a   Koehler, Michael F T ^a   Bergeron, Philippe ^a   Elliott, Linda O ^b   Flygare, John A ^a   Franklin, Matthew C ^a   Gazzard, Lewis ^a   Keteltas, Stephen F ^a   Lau, Kevin ^a   Ly, Cuong Q ^a   Tsui, Vickie ^a   Fairbrother, Wayne J ^a  

^a GENENTECH INC   (United States)

^b Department of Biochemical Pharmacology ^*  (United States)

Author keywords

IAP antagonist; Peptidomimetic; Protein protein interaction

Indexed keywords

AMIDE; LIVIN; THIAZOLE DERIVATIVE; X LINKED INHIBITOR OF APOPTOSIS;

ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; FLUORESCENCE POLARIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMIDES; BINDING SITES; BIOMIMETICS; CRYSTALLOGRAPHY, X-RAY; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MODELS, MOLECULAR; PEPTIDES; THIAZOLES;

EID: 77949488829     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.02.021     Document Type: Article

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