Design and synthesis of novel 3,4-disubstituted pyrazoles for nanomedicine applications against malignant gliomas

European Journal of Medicinal Chemistry

Volumn 45, Issue 5, 2010, Pages 2024-2033

  Comes Franchini, Mauro ^a   Bonini, Bianca Flavia ^a   Camaggi, Carlo Maurizio ^a   Gentili, Denis ^a   Pession, Annalisa ^b   Rani, Monica ^b   Strocchi, Elena ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b BELLARIA HOSPITAL   (Italy)

Author keywords

Docking; Drug delivery; Glioblastoma; Nanomedicine; Pyrazoles

Indexed keywords

12 AMINO N (1,3 DIPHENYL 1H PYRAZOL 4 YL)DODECANAMIDE; 12 AMINO N (1,3 DIPHENYL 1H PYRAZOL 4 YL)DODECANETHIOAMIDE; 12 AMINO N [1 METHYL 3 (PYRID 2 YL) 1H PYRAZOL 4 YL]DODECANAMIDE; 2 METHOXY N (1,3 DIPHENYL 1H PYRAZOL 4 YL)BENZAMIDE; 4 AMINO 1,3 DIPHENYL PYRAZOLE; MACROGOL; N (1,3 DIPHENYL 1H PYRAZOL 4 YL) 11 MERCAPTOUNDECANAMIDE; N (1,3 DIPHENYL 1H PYRAZOL 4 YL)DODECANAMIDE; PHORBOL DIBUTYRATE; POLYGLACTIN; PYRAZOLE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; GLIOBLASTOMA; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MOLECULAR DOCKING; NANOMEDICINE; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; GLIOMA; HUMANS; MICELLES; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NANOMEDICINE; PYRAZOLES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77949485944     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.01.014     Document Type: Article

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