메뉴 건너뛰기




Volumn 23, Issue 4, 2010, Pages 1133-1138

p38 MAPK plays a distinct role in sulforaphane-induced up-regulation of ARE-dependent enzymes and down-regulation of COX-2 in human bladder cancer cells

Author keywords

Antioxidant response element; Bladder cancer; Isothiocyanate; p38 MAPK; Sulforaphane

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANISOMYCIN; CYCLOOXYGENASE 2; GLUTATHIONE TRANSFERASE A1; MITOGEN ACTIVATED PROTEIN KINASE P38; SULFORAPHANE; THIOREDOXIN REDUCTASE 1;

EID: 77949430099     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000742     Document Type: Article
Times cited : (37)

References (31)
  • 1
    • 0036045433 scopus 로고    scopus 로고
    • Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells
    • Basten GP, Bao Y and Williamson G: Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells. Carcinogenesis 23: 1399-1404, 2002.
    • (2002) Carcinogenesis , vol.23 , pp. 1399-1404
    • Basten, G.P.1    Bao, Y.2    Williamson, G.3
  • 2
    • 33748166145 scopus 로고    scopus 로고
    • Evaluation of isothiocyanates as potent inducers of carcinogen-detoxifying enzymes in the urinary bladder: Critical nature of in vivo bioassay
    • Munday R, Zhang Y, Fahey JW, Jobson HE, Munday CM, Li J and Stephenson KK: Evaluation of isothiocyanates as potent inducers of carcinogen-detoxifying enzymes in the urinary bladder: critical nature of in vivo bioassay. Nutr Cancer 54: 223-231, 2006.
    • (2006) Nutr Cancer , vol.54 , pp. 223-231
    • Munday, R.1    Zhang, Y.2    Fahey, J.W.3    Jobson, H.E.4    Munday, C.M.5    Li, J.6    Stephenson, K.K.7
  • 3
    • 33646087882 scopus 로고    scopus 로고
    • The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells
    • Tang L, Li G, Song L and Zhang Y: The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells. Anti-cancer Drugs 17: 297-305, 2006.
    • (2006) Anti-cancer Drugs , vol.17 , pp. 297-305
    • Tang, L.1    Li, G.2    Song, L.3    Zhang, Y.4
  • 4
    • 33846153232 scopus 로고    scopus 로고
    • Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts
    • Zhang Y, Munday R, Jobson HE, Munday CM, Lister C, Wilson P, Fahey JW and Mhawech-Fauceglia P: Induction of GST and NQO1 in cultured bladder cells and in the urinary bladders of rats by an extract of broccoli (Brassica oleracea italica) sprouts. J Agric Food Chem 54: 9370-9376, 2006.
    • (2006) J Agric Food Chem , vol.54 , pp. 9370-9376
    • Zhang, Y.1    Munday, R.2    Jobson, H.E.3    Munday, C.M.4    Lister, C.5    Wilson, P.6    Fahey, J.W.7    Mhawech-Fauceglia, P.8
  • 5
    • 0033381747 scopus 로고    scopus 로고
    • The role of human glutathione S-transferases M1 and T1 in individual susceptibility to bladder cancer
    • Salagovic J, Kalina I, Habalova V, Hrivnak M, Valansky L and Biros E: The role of human glutathione S-transferases M1 and T1 in individual susceptibility to bladder cancer. Physiol Res 48: 465-471, 1999.
    • (1999) Physiol Res , vol.48 , pp. 465-471
    • Salagovic, J.1    Kalina, I.2    Habalova, V.3    Hrivnak, M.4    Valansky, L.5    Biros, E.6
  • 7
    • 14644436340 scopus 로고    scopus 로고
    • Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells
    • Wang W, Wang S, Howie AF, Beckett GJ, Mithen R and Bao Y: Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells. J Agric Food Chem 53: 1417-1421, 2005.
    • (2005) J Agric Food Chem , vol.53 , pp. 1417-1421
    • Wang, W.1    Wang, S.2    Howie, A.F.3    Beckett, G.J.4    Mithen, R.5    Bao, Y.6
  • 8
    • 0345700812 scopus 로고    scopus 로고
    • Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation
    • Zhang J, Svehlikova V, Bao Y, Howie AF, Beckett GJ and Williamson G: Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation. Carcinogenesis 24: 497-503, 2003.
    • (2003) Carcinogenesis , vol.24 , pp. 497-503
    • Zhang, J.1    Svehlikova, V.2    Bao, Y.3    Howie, A.F.4    Beckett, G.J.5    Williamson, G.6
  • 9
    • 41549166452 scopus 로고    scopus 로고
    • Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes
    • Li D, Wu K, Howie AF, Beckett GJ, Wang W and Bao Y: Synergy between broccoli sprout extract and selenium in the upregulation of thioredoxin reductase in human hepatocytes. Food Chem 110: 193-198, 2008.
    • (2008) Food Chem , vol.110 , pp. 193-198
    • Li, D.1    Wu, K.2    Howie, A.F.3    Beckett, G.J.4    Wang, W.5    Bao, Y.6
  • 10
    • 0035212419 scopus 로고    scopus 로고
    • Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)
    • Kong AN, Owuor E, Yu R, Hebbar V, Chen C, Hu R and Mandlekar S: Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). Drug Metab Rev 33: 255-271, 2001.
    • (2001) Drug Metab Rev , vol.33 , pp. 255-271
    • Kong, A.N.1    Owuor, E.2    Yu, R.3    Hebbar, V.4    Chen, C.5    Hu, R.6    Mandlekar, S.7
  • 12
    • 0034687543 scopus 로고    scopus 로고
    • Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes
    • Zipper LM and Mulcahy RT: Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes. Biochem Biophys Res Commun 278: 484-492, 2000.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 484-492
    • Zipper, L.M.1    Mulcahy, R.T.2
  • 13
    • 33749019130 scopus 로고    scopus 로고
    • Mechanism of action of sulforaphane: Inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response elementmediated heme oxygenase-1 in human hepatoma HepG2 cells
    • Keum YS, Yu S, Chang PP, Yuan X, Kim JH, Xu C, Han J, Agarwal A and Kong AN: Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response elementmediated heme oxygenase-1 in human hepatoma HepG2 cells. Cancer Res 66: 8804-8813, 2006.
    • (2006) Cancer Res , vol.66 , pp. 8804-8813
    • Keum, Y.S.1    Yu, S.2    Chang, P.P.3    Yuan, X.4    Kim, J.H.5    Xu, C.6    Han, J.7    Agarwal, A.8    Kong, A.N.9
  • 14
    • 0032483712 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in tumorigenesis (Part II)
    • Taketo MM: Cyclooxygenase-2 inhibitors in tumorigenesis (Part II). J Natl Cancer Inst 90: 1609-1620, 1998.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1609-1620
    • Taketo, M.M.1
  • 15
    • 0037366062 scopus 로고    scopus 로고
    • Cyclooxygenase-2 is highly expressed in carcinoma in situ and T1 transitional cell carcinoma of the bladder
    • Shariat SF, Kim JH, Ayala GE, Kho K, Wheeler TM and Lerner SP: Cyclooxygenase-2 is highly expressed in carcinoma in situ and T1 transitional cell carcinoma of the bladder. J Urol 169: 938-942, 2003.
    • (2003) J Urol , vol.169 , pp. 938-942
    • Shariat, S.F.1    Kim, J.H.2    Ayala, G.E.3    Kho, K.4    Wheeler, T.M.5    Lerner, S.P.6
  • 16
    • 67649417900 scopus 로고    scopus 로고
    • Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-kappaB-DNA-binding activity in human bladder T24 cells
    • Shan Y, Wu K, Wang W, Wang S, Lin N, Zhao R, Cassidy A and Bao Y: Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-kappaB-DNA-binding activity in human bladder T24 cells. Int J Oncol 34: 1129-1134, 2009.
    • (2009) Int J Oncol , vol.34 , pp. 1129-1134
    • Shan, Y.1    Wu, K.2    Wang, W.3    Wang, S.4    Lin, N.5    Zhao, R.6    Cassidy, A.7    Bao, Y.8
  • 17
    • 47049088244 scopus 로고    scopus 로고
    • p38 MAPK activation and mitochondrial depolarization mediate the cytotoxicity of Taiwan cobra phospholipase A2 on human neuroblastoma SK-N-SH cells
    • Chen KC, Kao PH, Lin SR and Chang LS: p38 MAPK activation and mitochondrial depolarization mediate the cytotoxicity of Taiwan cobra phospholipase A2 on human neuroblastoma SK-N-SH cells. Toxicol Lett 180: 53-58, 2008.
    • (2008) Toxicol Lett , vol.180 , pp. 53-58
    • Chen, K.C.1    Kao, P.H.2    Lin, S.R.3    Chang, L.S.4
  • 19
    • 37349028270 scopus 로고    scopus 로고
    • Efficacy of sulforaphane is mediated by p38 MAP kinase and caspase-7 activations in ER-positive and COX-2-expressed human breast cancer cells
    • Jo EH, Kim SH, Ahn NS, Park JS, Hwang JW, Lee YS and Kang KS: Efficacy of sulforaphane is mediated by p38 MAP kinase and caspase-7 activations in ER-positive and COX-2-expressed human breast cancer cells. Eur J Cancer Prev 16: 505-510, 2007.
    • (2007) Eur J Cancer Prev , vol.16 , pp. 505-510
    • Jo, E.H.1    Kim, S.H.2    Ahn, N.S.3    Park, J.S.4    Hwang, J.W.5    Lee, Y.S.6    Kang, K.S.7
  • 20
    • 0034623211 scopus 로고    scopus 로고
    • Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor
    • Alam J, Wicks C, Stewart D, Gong P, Touchard C, Otterbein S, Choi AM, Burow ME and Tou J: Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J Biol Chem 275: 27694-27702, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 27694-27702
    • Alam, J.1    Wicks, C.2    Stewart, D.3    Gong, P.4    Touchard, C.5    Otterbein, S.6    Choi, A.M.7    Burow, M.E.8    Tou, J.9
  • 21
    • 0036708902 scopus 로고    scopus 로고
    • Antioxidants and oxidants regulated signal transduction pathways
    • Owuor ED and Kong AN: Antioxidants and oxidants regulated signal transduction pathways. Biochem Pharmacol 64: 765-770, 2002.
    • (2002) Biochem Pharmacol , vol.64 , pp. 765-770
    • Owuor, E.D.1    Kong, A.N.2
  • 22
    • 19444379739 scopus 로고    scopus 로고
    • Nrf2 as a novel molecular target for chemoprevention
    • Lee JS and Surh YJ: Nrf2 as a novel molecular target for chemoprevention. Cancer Lett 224: 171-184, 2005.
    • (2005) Cancer Lett , vol.224 , pp. 171-184
    • Lee, J.S.1    Surh, Y.J.2
  • 23
    • 40449129950 scopus 로고    scopus 로고
    • Inhibition of urinary bladder carcinogenesis by broccoli sprouts
    • Munday R, Mhawech-Fauceglia P, Munday CM, et al: Inhibition of urinary bladder carcinogenesis by broccoli sprouts. Cancer Res 68: 1593-1600, 2008.
    • (2008) Cancer Res , vol.68 , pp. 1593-1600
    • Munday, R.1    Mhawech-Fauceglia, P.2    Munday, C.M.3
  • 24
    • 19344367171 scopus 로고    scopus 로고
    • Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucininduced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells
    • Jakubikova J, Sedlak J, Mithen R and Bao Y: Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucininduced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells. Biochem Pharmacol 69: 1543-1552, 2005.
    • (2005) Biochem Pharmacol , vol.69 , pp. 1543-1552
    • Jakubikova, J.1    Sedlak, J.2    Mithen, R.3    Bao, Y.4
  • 25
    • 23844505236 scopus 로고    scopus 로고
    • Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells
    • Tang L and Zhang Y: Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells. Mol Cancer Ther 4: 1250-1259, 2005.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1250-1259
    • Tang, L.1    Zhang, Y.2
  • 26
    • 34247622975 scopus 로고    scopus 로고
    • Effect of sulforaphane on cell growth, G(0)/G(1) phase cell progression and apoptosis in human bladder cancer T24 cells
    • Shan Y, Sun C, Zhao X, Wu K, Cassidy A and Bao Y: Effect of sulforaphane on cell growth, G(0)/G(1) phase cell progression and apoptosis in human bladder cancer T24 cells. Int J Oncol 29: 883-888, 2006.
    • (2006) Int J Oncol , vol.29 , pp. 883-888
    • Shan, Y.1    Sun, C.2    Zhao, X.3    Wu, K.4    Cassidy, A.5    Bao, Y.6
  • 27
    • 52449089630 scopus 로고    scopus 로고
    • Direct and indirect antioxidant properties of inducers of cytoprotective proteins
    • Dinkova-Kostova AT and Talalay P: Direct and indirect antioxidant properties of inducers of cytoprotective proteins. Mol Nutr Food Res 52: S128-S138, 2008.
    • (2008) Mol Nutr Food Res , vol.52
    • Dinkova-Kostova, A.T.1    Talalay, P.2
  • 28
    • 0036124306 scopus 로고    scopus 로고
    • Modes of activation of mitogen-activated protein kinases and their roles in cepharanthine-induced apoptosis in human leukemia cells
    • Wu J, Suzuki H, Akhand AA, Zhou YW, Hossain K and Nakashima I: Modes of activation of mitogen-activated protein kinases and their roles in cepharanthine-induced apoptosis in human leukemia cells. Cell Signal 14: 509-515, 2006.
    • (2006) Cell Signal , vol.14 , pp. 509-515
    • Wu, J.1    Suzuki, H.2    Akhand, A.A.3    Zhou, Y.W.4    Hossain, K.5    Nakashima, I.6
  • 29
    • 0034757779 scopus 로고    scopus 로고
    • Cell cycle regulation by p38 MAP kinases
    • Ambrosino C and Nebreda AR: Cell cycle regulation by p38 MAP kinases. Biol Cell 93: 47-51, 2001.
    • (2001) Biol Cell , vol.93 , pp. 47-51
    • Ambrosino, C.1    Nebreda, A.R.2
  • 30
    • 38049065866 scopus 로고    scopus 로고
    • Effect of Hibiscus anthocyanins-rich extract induces apoptosis of proliferating smooth muscle cell via activation of P38 MAPK and p53 pathway
    • Lo CW, Huang HP, Lin HM, Chien CT and Wang CJ: Effect of Hibiscus anthocyanins-rich extract induces apoptosis of proliferating smooth muscle cell via activation of P38 MAPK and p53 pathway. Mol Nutr Food Res 51: 1452-1460, 2007.
    • (2007) Mol Nutr Food Res , vol.51 , pp. 1452-1460
    • Lo, C.W.1    Huang, H.P.2    Lin, H.M.3    Chien, C.T.4    Wang, C.J.5
  • 31


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.