Efficacy of sulforaphane is mediated by p38 MAP kinase and caspase-7 activations in ER-positive and COX-2-expressed human breast cancer cells

European Journal of Cancer Prevention

Volumn 16, Issue 6, 2007, Pages 505-510

  Jo, Eun Hye ^a   Kim, Sung Hoon ^c   Ahn, Nam Shik ^a   Park, Joon Suk ^a,b   Hwang, Jae Woong ^a   Lee, Yong Soon ^a,b   Kang, Kyung Sun ^a,b  

^a Konkuk University   (South Korea)

^b Seoul National University   (South Korea)

^c Kyung Hee University   (South Korea)

Author keywords

Caspase 7; Chemoprevention; Human breast cancer; MAPK; Sulforaphane

Indexed keywords

CASPASE 7; CYCLOOXYGENASE 2; ESTROGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; SULFORAPHANE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER PREVENTION; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMOBILIZED CELL; PHENOTYPE; PRIORITY JOURNAL; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASE 7; CELL LINE, TRANSFORMED; CELL NUCLEUS SHAPE; CELL PROLIFERATION; CELL SURVIVAL; CYCLOOXYGENASE 2; CYTOPROTECTION; DRUG EVALUATION, PRECLINICAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASMS, HORMONE-DEPENDENT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, ESTROGEN; THIOCYANATES; TREATMENT OUTCOME; TUMOR CELLS, CULTURED;

EID: 37349028270     PISSN: 09598278     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.cej.0000243856.97479.3b     Document Type: Article

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