Dissecting the mechanism of insulin resistance using a novel heterodimerization strategy to activate akt

Journal of Biological Chemistry

Volumn 285, Issue 8, 2010, Pages 5232-5239

  Ng, Yvonne ^a,b   Ramm, Georg ^a,c   James, David E ^a,b  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

3T3-L1 ADIPOCYTES; CHRONIC EXPOSURE; CHRONIC INSULIN; CONTROL-CELL; DEXAMETHASONES; FEED-FORWARD; GLUCOSE TRANSPORTER 4; HETERODIMERIZATION; INHIBITORY MECHANISM; INSULIN RECEPTORS; INSULIN RESISTANCE; INSULIN SIGNALING; MAMMALIAN TARGET; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3-KINASE; WORTMANNIN;

DEFECTS; GLUCOSE; MAMMALS; PHOSPHORYLATION;

INSULIN;

DEXAMETHASONE; GLUCOSE TRANSPORTER 4; HEMAGGLUTININ; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE B BETA; WORTMANNIN; AKT2 PROTEIN, MOUSE; ANTIDIABETIC AGENT; ANTIINFLAMMATORY AGENT; SLC2A4 PROTEIN, MOUSE;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; INSULIN RESISTANCE; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN LOCALIZATION; ANIMAL; DRUG EFFECT; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TRANSPORT;

MAMMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3-L1 CELLS; ANIMALS; ANTI-INFLAMMATORY AGENTS; DEXAMETHASONE; ENZYME ACTIVATION; GLUCOSE TRANSPORTER TYPE 4; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MICE; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 77949321235     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.060632     Document Type: Article

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