-
1
-
-
0027982995
-
Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity
-
Chen L, McGowan P, Ashe S, et al. Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity. J Exp Med, 1994, 179: 523-532.
-
(1994)
J Exp Med
, vol.179
, pp. 523-532
-
-
Chen, L.1
McGowan, P.2
Ashe, S.3
-
4
-
-
0026537347
-
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
-
Harding F A, McArthur J G, Gross J A, et al. CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature, 1992, 356: 607-609.
-
(1992)
Nature
, vol.356
, pp. 607-609
-
-
Harding, F.A.1
McArthur, J.G.2
Gross, J.A.3
-
5
-
-
2442585121
-
Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
-
Chen L. Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. Nat Rev Immunol, 2004, 4: 336-347.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 336-347
-
-
Chen, L.1
-
6
-
-
0036214017
-
The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
-
Carreno B M, Collins M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu Rev Immunol, 2002, 20: 29-53.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 29-53
-
-
Carreno, B.M.1
Collins, M.2
-
7
-
-
0035967157
-
Structural basis for co-stimulation by the human CTLA-4/B7-2 complex
-
Schwartz J C, Zhang X, Fedorov A A, et al. Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature, 2001, 410: 604-608.
-
(2001)
Nature
, vol.410
, pp. 604-608
-
-
Schwartz, J.C.1
Zhang, X.2
Fedorov, A.A.3
-
8
-
-
0035967146
-
Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses
-
Stamper C C, Zhang Y, Tobin J F, et al. Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses. Nature, 2001, 410: 608-611.
-
(2001)
Nature
, vol.410
, pp. 608-611
-
-
Stamper, C.C.1
Zhang, Y.2
Tobin, J.F.3
-
9
-
-
0037089648
-
Ligand binding sites of inducible costimulator and high avidity mutants with improved function
-
Wang S, Zhu G, Tamada K, et al. Ligand binding sites of inducible costimulator and high avidity mutants with improved function. J Exp Med, 2002, 195: 1033-1041.
-
(2002)
J Exp Med
, vol.195
, pp. 1033-1041
-
-
Wang, S.1
Zhu, G.2
Tamada, K.3
-
10
-
-
12144290320
-
Structural and functional analysis of the costimulatory receptor programmed death-1
-
Zhang X, Schwartz J C, Guo X, et al. Structural and functional analysis of the costimulatory receptor programmed death-1. Immunity, 2004, 20: 337-347.
-
(2004)
Immunity
, vol.20
, pp. 337-347
-
-
Zhang, X.1
Schwartz, J.C.2
Guo, X.3
-
11
-
-
0038185203
-
Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction
-
Wang S, Bajorath J, Flies D B, et al. Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J Exp Med, 2003, 197: 1083-1091.
-
(2003)
J Exp Med
, vol.197
, pp. 1083-1091
-
-
Wang, S.1
Bajorath, J.2
Flies, D.B.3
-
12
-
-
42949160646
-
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
-
Lin D Y, Tanaka Y, Iwasaki M, et al. The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc Natl Acad Sci USA, 2008, 105: 3011-3016.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3011-3016
-
-
Lin, D.Y.1
Tanaka, Y.2
Iwasaki, M.3
-
13
-
-
48749095324
-
Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2
-
Lazar-Molnar E, Yan Q, Cao E, et al. Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2. Proc Natl Acad Sci USA, 2008, 105: 10483-10488.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10483-10488
-
-
Lazar-Molnar, E.1
Yan, Q.2
Cao, E.3
-
14
-
-
4444369694
-
B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse
-
Pentcheva-Hoang T, Egen J G, Wojnoonski K, et al. B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse. Immunity, 2004, 21: 401-413.
-
(2004)
Immunity
, vol.21
, pp. 401-413
-
-
Pentcheva-Hoang, T.1
Egen, J.G.2
Wojnoonski, K.3
-
15
-
-
36749010774
-
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
-
Pentcheva-Hoang T, Chen L, Pardoll D M, et al. Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability. Proc Natl Acad Sci USA, 2007, 104: 17765-17770.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 17765-17770
-
-
Pentcheva-Hoang, T.1
Chen, L.2
Pardoll, D.M.3
-
16
-
-
0024539057
-
Structure of tumour necrosis factor
-
Jones E Y, Stuart D I, Walker N P. Structure of tumour necrosis factor. Nature, 1989, 338: 225-228.
-
(1989)
Nature
, vol.338
, pp. 225-228
-
-
Jones, E.Y.1
Stuart, D.I.2
Walker, N.P.3
-
17
-
-
0028353492
-
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
-
Smith C A, Farrah T, Goodwin R G. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell, 1994, 76: 959-962.
-
(1994)
Cell
, vol.76
, pp. 959-962
-
-
Smith, C.A.1
Farrah, T.2
Goodwin, R.G.3
-
19
-
-
0027211704
-
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
-
Banner D W, D'Arcy A, Janes W, et al. Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation. Cell, 1993, 73: 431-445.
-
(1993)
Cell
, vol.73
, pp. 431-445
-
-
Banner, D.W.1
D'Arcy, A.2
Janes, W.3
-
21
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol E A, Borriello F, Schweitzer A N, et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity, 1995, 3: 541-547.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
-
22
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse P, Penninger J M, Timms E, et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science, 1995, 270: 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
23
-
-
0038153907
-
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
-
Phan G Q, Yang J C, Sherry R M, et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc Natl Acad Sci USA, 2003, 100: 8372-8377.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8372-8377
-
-
Phan, G.Q.1
Yang, J.C.2
Sherry, R.M.3
-
24
-
-
65349185047
-
The clinical utility of inhibiting CD28- mediated costimulation
-
Linsley P S, Nadler S G. The clinical utility of inhibiting CD28- mediated costimulation. Immunol Rev, 2009, 229: 307-321.
-
(2009)
Immunol Rev
, vol.229
, pp. 307-321
-
-
Linsley, P.S.1
Nadler, S.G.2
-
25
-
-
0026738641
-
Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg
-
Lenschow D J, Zeng Y, Thistlethwaite J R, et al. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg. Science, 1992, 257: 789-792.
-
(1992)
Science
, vol.257
, pp. 789-792
-
-
Lenschow, D.J.1
Zeng, Y.2
Thistlethwaite, J.R.3
-
26
-
-
20044386299
-
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties
-
Larsen C P, Pearson T C, Adams A B, et al. Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am J Transplant, 2005, 5: 443-453.
-
(2005)
Am J Transplant
, vol.5
, pp. 443-453
-
-
Larsen, C.P.1
Pearson, T.C.2
Adams, A.B.3
-
28
-
-
0028675006
-
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
-
Linsley P S, Greene J L, Brady W, et al. Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity, 1994, 1: 793-801.
-
(1994)
Immunity
, vol.1
, pp. 793-801
-
-
Linsley, P.S.1
Greene, J.L.2
Brady, W.3
-
29
-
-
0027937702
-
Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1
-
Peach R J, Bajorath J, Brady W, et al. Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. J Exp Med, 1994, 180: 2049-2058.
-
(1994)
J Exp Med
, vol.180
, pp. 2049-2058
-
-
Peach, R.J.1
Bajorath, J.2
Brady, W.3
-
30
-
-
20044386299
-
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties
-
Larsen C P, Pearson T C, Adams A B, et al. Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. Am J Transplant, 2005, 5: 443-453.
-
(2005)
Am J Transplant
, vol.5
, pp. 443-453
-
-
Larsen, C.P.1
Pearson, T.C.2
Adams, A.B.3
-
31
-
-
33644829825
-
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways
-
Cardona K, Korbutt G S, Milas Z, et al. Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways. Nat Med, 2006, 12: 304-306.
-
(2006)
Nat Med
, vol.12
, pp. 304-306
-
-
Cardona, K.1
Korbutt, G.S.2
Milas, Z.3
-
32
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
Dong H, Zhu G, Tamada K, et al. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med, 1999, 5: 1365-1369.
-
(1999)
Nat Med
, vol.5
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
-
33
-
-
0035794314
-
B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
-
Tseng S Y, Otsuji M, Gorski K, et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med, 2001, 193: 839-846.
-
(2001)
J Exp Med
, vol.193
, pp. 839-846
-
-
Tseng, S.Y.1
Otsuji, M.2
Gorski, K.3
-
34
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura H, Nose M, Hiai H, et al. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity, 1999, 11: 141-151.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
-
35
-
-
0035846991
-
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice
-
Nishimura H, Okazaki T, Tanaka Y, et al. Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. Science, 2001, 291: 319-322.
-
(2001)
Science
, vol.291
, pp. 319-322
-
-
Nishimura, H.1
Okazaki, T.2
Tanaka, Y.3
-
36
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman Y, Wood C R, Chernova T, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol, 2001, 2: 261-268.
-
(2001)
Nat Immunol
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
-
37
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman G J, Long A J, Iwai Y, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med, 2000, 192: 1027-1034.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
-
39
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
Butte M J, Keir M E, Phamduy T B, et al. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity, 2007, 27: 111-122.
-
(2007)
Immunity
, vol.27
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
-
40
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H, Strome S E, Salomao D R, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med, 2002, 8: 793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
-
41
-
-
65349156913
-
Costimulatory and coinhibitory receptors in anti-tumor immunity
-
Driessens G, Kline J, Gajewski T F. Costimulatory and coinhibitory receptors in anti-tumor immunity. Immunol Rev, 2009, 229: 126-144.
-
(2009)
Immunol Rev
, vol.229
, pp. 126-144
-
-
Driessens, G.1
Kline, J.2
Gajewski, T.F.3
-
42
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber D L, Wherry E J, Masopust D, et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature, 2006, 439: 682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
-
43
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir M E, Butte M J, Freeman G J, et al. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol, 2008, 26: 677-704.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
|