-
1
-
-
0016840934
-
The metabolism of lipids in mouse pancreatic islets. The biosynthesis of triacylglycerols and phospholipids
-
Berne C. 1975a. The metabolism of lipids in mouse pancreatic islets. The biosynthesis of triacylglycerols and phospholipids. Biochem J 152:667-673.
-
(1975)
Biochem J
, vol.152
, pp. 667-673
-
-
Berne, C.1
-
2
-
-
0016775657
-
The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies
-
Berne C. 1975b. The metabolism of lipids in mouse pancreatic islets. The oxidation of fatty acids and ketone bodies. Biochem J 152:661-666.
-
(1975)
Biochem J
, vol.152
, pp. 661-666
-
-
Berne, C.1
-
3
-
-
41149178575
-
Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids
-
Bikopoulos G, da Silva Pimenta A, Lee SC, Lakey JR, Der SD, Chan CB, Ceddia RB, Wheeler MB, Rozakis-Adcock M. 2008. Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids. J Endocrinol 196:455-464.
-
(2008)
J Endocrinol
, vol.196
, pp. 455-464
-
-
Bikopoulos, G.1
da Silva2
Pimenta, A.3
Lee, S.C.4
Lakey, J.R.5
SD, D.6
Chan, C.B.7
Ceddia, R.B.8
Wheeler, M.B.9
Rozakis-Adcock, M.10
-
4
-
-
3042591440
-
Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue
-
Boucher A, Lu D, Burgess SC, Telemaque-Potts S, Jensen MV, Mulder H, Wang MY, Unger RH, Sherry AD, Newgard CB. 2004. Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue. J Biol Chem 279:27263-27271.
-
(2004)
J Biol Chem
, vol.279
, pp. 27263-27271
-
-
Boucher, A.1
Lu, D.2
Burgess, S.C.3
Telemaque-Potts, S.4
Jensen, M.V.5
Mulder, H.6
Wang, M.Y.7
Unger, R.H.8
Sherry, A.D.9
Newgard, C.B.10
-
5
-
-
0031054064
-
Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1
-
Brun T, Assimacopoulos-Jeannet F, Corkey BE, Prentki M. 1997. Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. Diabetes 46:393-400.
-
(1997)
Diabetes
, vol.46
, pp. 393-400
-
-
Brun, T.1
Assimacopoulos-Jeannet, F.2
Corkey, B.E.3
Prentki, M.4
-
6
-
-
25844454854
-
Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis
-
Busch AK, Gurisik E, Cordery DV, Sudlow M, Denyer GS, Laybutt DR, Hughes WE, Biden TJ. 2005. Increased fatty acid desaturation and enhanced expression of stearoyl coenzyme A desaturase protects pancreatic beta-cells from lipoapoptosis. Diabetes 54:2917-2924.
-
(2005)
Diabetes
, vol.54
, pp. 2917-2924
-
-
Busch, A.K.1
Gurisik, E.2
Cordery, D.V.3
Sudlow, M.4
Denyer, G.S.5
Laybutt, D.R.6
Hughes, W.E.7
Biden, T.J.8
-
7
-
-
0034681341
-
Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes
-
Clifford GM, Londos C, Kraemer FB, Vernon RG, Yeaman SJ. 2000. Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes. J Biol Chem 275:5011-5015.
-
(2000)
J Biol Chem
, vol.275
, pp. 5011-5015
-
-
Clifford, G.M.1
Londos, C.2
Kraemer, F.B.3
Vernon, R.G.4
Yeaman, S.J.5
-
8
-
-
0031683543
-
Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
-
Dobbins RL, Chester MW, Daniels MB, McGarry JD, Stein DT. 1998. Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans. Diabetes 47:1613-1618.
-
(1998)
Diabetes
, vol.47
, pp. 1613-1618
-
-
Dobbins, R.L.1
Chester, M.W.2
Daniels, M.B.3
McGarry, J.D.4
Stein, D.T.5
-
9
-
-
0036260126
-
The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats
-
Dobbins RL, Szczepaniak LS, Myhill J, Tamura Y, Uchino H, Giacca A, McGarry JD. 2002. The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. Diabetes 51:1825-1833.
-
(2002)
Diabetes
, vol.51
, pp. 1825-1833
-
-
Dobbins, R.L.1
Szczepaniak, L.S.2
Myhill, J.3
Tamura, Y.4
Uchino, H.5
Giacca, A.6
McGarry, J.D.7
-
10
-
-
53849110273
-
Lipases in the pancreatic beta-cell: Implications for insulin secretion
-
Fex M, Mulder H. 2008. Lipases in the pancreatic beta-cell: Implications for insulin secretion. Biochem Soc Trans 36:885-890.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 885-890
-
-
Fex, M.1
Mulder, H.2
-
11
-
-
3843052408
-
Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact
-
Fex M, Olofsson CS, Fransson U, Bacos K, Lindvall H, Sorhede-Winzell M, Rorsman P, Holm C, Mulder H. 2004. Hormone-sensitive lipase deficiency in mouse islets abolishes neutral cholesterol ester hydrolase activity but leaves lipolysis, acylglycerides, fat oxidation, and insulin secretion intact. Endocrinology 145:3746-3753.
-
(2004)
Endocrinology
, vol.145
, pp. 3746-3753
-
-
Fex, M.1
Olofsson, C.S.2
Fransson, U.3
Bacos, K.4
Lindvall, H.5
Sorhede-Winzell, M.6
Rorsman, P.7
Holm, C.8
Mulder, H.9
-
12
-
-
33845528419
-
-
Fex M, Lucas S, Winzell MS, Ahren B, Holm C, Mulder H. 2006. {beta}-Cell lipases and insulin secretion. Diabetes 55(Suppl 2): S24-S31.
-
Fex M, Lucas S, Winzell MS, Ahren B, Holm C, Mulder H. 2006. {beta}-Cell lipases and insulin secretion. Diabetes 55(Suppl 2): S24-S31.
-
-
-
-
13
-
-
59049098636
-
Stearoyl-CoAdesaturase andits relationtohighcarbohydrate diets and obesity
-
FlowersMT, Ntambi JM.2009. Stearoyl-CoAdesaturase andits relationtohighcarbohydrate diets and obesity. Biochim Biophys Acta 1791:85-91.
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 85-91
-
-
Flowers, M.T.1
Ntambi, J.M.2
-
14
-
-
34248198871
-
Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice
-
Flowers JB, Rabaglia ME, Schueler KL, Flowers MT, Lan H, Keller MP, Ntambi JM, Attie AD. 2007. Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice. Diabetes 56:1228-1239.
-
(2007)
Diabetes
, vol.56
, pp. 1228-1239
-
-
Flowers, J.B.1
Rabaglia, M.E.2
Schueler, K.L.3
Flowers, M.T.4
Lan, H.5
Keller, M.P.6
Ntambi, J.M.7
Attie, A.D.8
-
15
-
-
70349611130
-
Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca2+-channels from secretory vesicles
-
Hoppa MB, Collins S, Ramracheya R, Hodson L, Amisten S, Zhang Q, Johnson P, Ashcroft FM, Rorsman P. 2009. Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca2+-channels from secretory vesicles. Cell Metabolism 10:455-465.
-
(2009)
Cell Metabolism
, vol.10
, pp. 455-465
-
-
Hoppa, M.B.1
Collins, S.2
Ramracheya, R.3
Hodson, L.4
Amisten, S.5
Zhang, Q.6
Johnson, P.7
Ashcroft, F.M.8
Rorsman, P.9
-
16
-
-
0141755328
-
A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes
-
Kashyap S, Belfort R, Gastaldelli A, Pratipanawatr T, Berria R, Pratipanawatr W, Bajaj M, Mandarino L, DeFronzo R, Cusi K. 2003. A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes. Diabetes 52:2461-2474.
-
(2003)
Diabetes
, vol.52
, pp. 2461-2474
-
-
Kashyap, S.1
Belfort, R.2
Gastaldelli, A.3
Pratipanawatr, T.4
Berria, R.5
Pratipanawatr, W.6
Bajaj, M.7
Mandarino, L.8
DeFronzo, R.9
Cusi, K.10
-
17
-
-
0042531617
-
Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis
-
Kelpe CL, Moore PC, Parazzoli SD, Wicksteed B, Rhodes CJ, Poitout V. 2003. Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis. J Biol Chem 278:30015-30021.
-
(2003)
J Biol Chem
, vol.278
, pp. 30015-30021
-
-
Kelpe, C.L.1
Moore, P.C.2
Parazzoli, S.D.3
Wicksteed, B.4
Rhodes, C.J.5
Poitout, V.6
-
18
-
-
9244231766
-
Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress
-
Kharroubi I, Ladriere L, Cardozo AK, Dogusan Z, Cnop M, Eizirik DL. 2004. Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: Role of nuclear factor-kappaB and endoplasmic reticulum stress. Endocrinology 145:5087-5096.
-
(2004)
Endocrinology
, vol.145
, pp. 5087-5096
-
-
Kharroubi, I.1
Ladriere, L.2
Cardozo, A.K.3
Dogusan, Z.4
Cnop, M.5
Eizirik, D.L.6
-
19
-
-
33748489928
-
BCL-6: A possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells
-
Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL, Cnop M. 2006. BCL-6: A possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells. Diabetologia 49:2350-2358.
-
(2006)
Diabetologia
, vol.49
, pp. 2350-2358
-
-
Kharroubi, I.1
Lee, C.H.2
Hekerman, P.3
Darville, M.I.4
Evans, R.M.5
Eizirik, D.L.6
Cnop, M.7
-
20
-
-
19444384126
-
Obesity and fat quantification in lean tissues using three-point Dixon MR imaging
-
Kovanlikaya A, Mittelman SD, Ward A, Geffner ME, Dorey F, Gilsanz V. 2005. Obesity and fat quantification in lean tissues using three-point Dixon MR imaging. Pediatr Radiol 35:601-607.
-
(2005)
Pediatr Radiol
, vol.35
, pp. 601-607
-
-
Kovanlikaya, A.1
Mittelman, S.D.2
Ward, A.3
Geffner, M.E.4
Dorey, F.5
Gilsanz, V.6
-
21
-
-
40449106191
-
Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic {beta}-cells
-
Lai E, Bikopoulos G, Wheeler MB, Rozakis-Adcock M, Volchuk A. 2008. Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic {beta}-cells. Am J Physiol Endocrinol Metab 294:E540-E550.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Lai, E.1
Bikopoulos, G.2
Wheeler, M.B.3
Rozakis-Adcock, M.4
Volchuk, A.5
-
22
-
-
33746419647
-
Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects
-
Larson-Meyer DE, Heilbronn LK, Redman LM, Newcomer BR, Frisard MI, Anton S, Smith SR, Alfonso A, Ravussin E. 2006. Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects. Diabetes Care 29:1337-1344.
-
(2006)
Diabetes Care
, vol.29
, pp. 1337-1344
-
-
Larson-Meyer, D.E.1
Heilbronn, L.K.2
Redman, L.M.3
Newcomer, B.R.4
Frisard, M.I.5
Anton, S.6
Smith, S.R.7
Alfonso, A.8
Ravussin, E.9
-
23
-
-
55149108075
-
Nonalcoholic fatty liver disease: The potential role of nutritional management
-
Leclercq IA, Horsmans Y. 2008. Nonalcoholic fatty liver disease: The potential role of nutritional management. Curr Opin Clin Nutr Metab Care 11:766-773.
-
(2008)
Curr Opin Clin Nutr Metab Care
, vol.11
, pp. 766-773
-
-
Leclercq, I.A.1
Horsmans, Y.2
-
24
-
-
0036318319
-
Lipotoxicity in human pancreatic islets and the protective effect of metformin
-
Lupi R, Del Guerra S, Fierabracci V, Marselli L, Novelli M, Patane G, Boggi U, Mosca F, Piro S, Del Prato S, Marchetti P. 2002. Lipotoxicity in human pancreatic islets and the protective effect of metformin. Diabetes 51(Suppl 1): S134-S137.
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 1
-
-
Lupi, R.1
Del Guerra, S.2
Fierabracci, V.3
Marselli, L.4
Novelli, M.5
Patane, G.6
Boggi, U.7
Mosca, F.8
Piro, S.9
Del Prato, S.10
Marchetti, P.11
-
25
-
-
1642414416
-
-
Lupi R, Del Guerra S, Marselli L, BuglianiM, Boggi U,Mosca F,Marchetti P, Del Prato S. 2004. Rosiglitazone prevents the impairment of human islet function induced by fatty acids: Evidence for a role of PPARgamma2 in the modulation of insulin secretion. Am J Physiol Endocrinol Metab 286:E560-E567.
-
Lupi R, Del Guerra S, Marselli L, BuglianiM, Boggi U,Mosca F,Marchetti P, Del Prato S. 2004. Rosiglitazone prevents the impairment of human islet function induced by fatty acids: Evidence for a role of PPARgamma2 in the modulation of insulin secretion. Am J Physiol Endocrinol Metab 286:E560-E567.
-
-
-
-
26
-
-
24944526652
-
Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro
-
Moffitt JH, Fielding BA, Evershed R, Berstan R, Currie JM, Clark A. 2005. Adverse physicochemical properties of tripalmitin in beta cells lead to morphological changes and lipotoxicity in vitro. Diabetologia 48:1819-1829.
-
(2005)
Diabetologia
, vol.48
, pp. 1819-1829
-
-
Moffitt, J.H.1
Fielding, B.A.2
Evershed, R.3
Berstan, R.4
Currie, J.M.5
Clark, A.6
-
27
-
-
0032933607
-
Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells
-
Mulder H, Holst LS, Svensson H, Degerman E, Sundler F, Ahren B, Rorsman P, Holm C. 1999. Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in beta-cells. Diabetes 48:228-232.
-
(1999)
Diabetes
, vol.48
, pp. 228-232
-
-
Mulder, H.1
Holst, L.S.2
Svensson, H.3
Degerman, E.4
Sundler, F.5
Ahren, B.6
Rorsman, P.7
Holm, C.8
-
28
-
-
3142753961
-
Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases
-
Nakamura MT, Nara TY. 2004. Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases. Annu Rev Nutr 24:345-376.
-
(2004)
Annu Rev Nutr
, vol.24
, pp. 345-376
-
-
Nakamura, M.T.1
Nara, T.Y.2
-
29
-
-
52249114681
-
The islet beta-cell: Fuel responsive and vulnerable
-
Nolan CJ, Prentki M. 2008. The islet beta-cell: Fuel responsive and vulnerable. Trends Endocrinol Metab 19:285-291.
-
(2008)
Trends Endocrinol Metab
, vol.19
, pp. 285-291
-
-
Nolan, C.J.1
Prentki, M.2
-
30
-
-
33845517309
-
Fatty acid signaling in the {beta}-cell and insulin secretion
-
Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M. 2006. Fatty acid signaling in the {beta}-cell and insulin secretion. Diabetes 55(Suppl 2): S16-S23.
-
(2006)
Diabetes
, vol.55
, Issue.SUPPL. 2
-
-
Nolan, C.J.1
Madiraju, M.S.2
Delghingaro-Augusto, V.3
Peyot, M.L.4
Prentki, M.5
-
31
-
-
34347382713
-
Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane
-
Olofsson CS, Collins S, Bengtsson M, Eliasson L, Salehi A, Shimomura K, Tarasov A, Holm C, Ashcroft F, Rorsman P. 2007. Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane. Diabetes 56:1888-1897.
-
(2007)
Diabetes
, vol.56
, pp. 1888-1897
-
-
Olofsson, C.S.1
Collins, S.2
Bengtsson, M.3
Eliasson, L.4
Salehi, A.5
Shimomura, K.6
Tarasov, A.7
Holm, C.8
Ashcroft, F.9
Rorsman, P.10
-
32
-
-
0018119115
-
Lipomatosis of the pancreas in autopsy material and its relation to age and overweight
-
Olsen TS. 1978. Lipomatosis of the pancreas in autopsy material and its relation to age and overweight. Acta Pathol Microbiol Scand [A] 86A:367-373.
-
(1978)
Acta Pathol Microbiol Scand
, vol.86 A
, Issue.A
, pp. 367-373
-
-
Olsen, T.S.1
-
33
-
-
1042291856
-
Fasting plasma free fatty acids and risk of type 2 diabetes: The atherosclerosis risk in communities study
-
PankowJS,DuncanBB, SchmidtMI,BallantyneCM, CouperDJ,HoogeveenRC, Golden SH. 2004. Fasting plasma free fatty acids and risk of type 2 diabetes: The atherosclerosis risk in communities study. Diabetes Care 27:77-82.
-
(2004)
Diabetes Care
, vol.27
, pp. 77-82
-
-
Pankow, J.S.1
Duncan, B.B.2
Schmidt, M.I.3
Ballantyne, C.M.4
Couper, D.J.5
Hoogeveen, R.C.6
Golden, S.H.7
-
34
-
-
0031753344
-
Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes
-
Paolisso G, Tagliamonte MR, Rizzo MR, Gualdiero P, Saccomanno F, Gambardella A, Giugliano D, D'Onofrio F, Howard BV. 1998. Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes. Diabetologia 41:1127-1132.
-
(1998)
Diabetologia
, vol.41
, pp. 1127-1132
-
-
Paolisso, G.1
Tagliamonte, M.R.2
Rizzo, M.R.3
Gualdiero, P.4
Saccomanno, F.5
Gambardella, A.6
Giugliano, D.7
D'Onofrio, F.8
Howard, B.V.9
-
35
-
-
0033565662
-
Metabolic characteristics of a human hepatoma cell line stably transfected with hormone-sensitive lipase
-
Pease RJ, Wiggins D, Saggerson ED, Tree J, Gibbons GF. 1999. Metabolic characteristics of a human hepatoma cell line stably transfected with hormone-sensitive lipase. Biochem J 341(Pt 2): 453-460.
-
(1999)
Biochem J
, vol.341
, Issue.PART 2
, pp. 453-460
-
-
Pease, R.J.1
Wiggins, D.2
Saggerson, E.D.3
Tree, J.4
Gibbons, G.F.5
-
36
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW. 2001. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
37
-
-
85120591717
-
-
Pinnick KE, Collins SC, Londos C, Gauguier D, Clark A, Fielding BA. 2008. Pancreatic ectopic fat is characterized by adipocyte infiltration and altered lipid composition. Obesity (Silver Spring) 16:522-530.
-
Pinnick KE, Collins SC, Londos C, Gauguier D, Clark A, Fielding BA. 2008. Pancreatic ectopic fat is characterized by adipocyte infiltration and altered lipid composition. Obesity (Silver Spring) 16:522-530.
-
-
-
-
38
-
-
0034630397
-
Electrospray ionization mass spectrometric analyses of phospholipids from INS-1 insulinoma cells: Comparison to pancreatic islets and effects of fatty acid supplementation on phospholipid composition and insulin secretion
-
Ramanadham S, Hsu F, Zhang S, Bohrer A, Ma Z, Turk J. 2000. Electrospray ionization mass spectrometric analyses of phospholipids from INS-1 insulinoma cells: Comparison to pancreatic islets and effects of fatty acid supplementation on phospholipid composition and insulin secretion. Biochim Biophys Acta 1484:251-266.
-
(2000)
Biochim Biophys Acta
, vol.1484
, pp. 251-266
-
-
Ramanadham, S.1
Hsu, F.2
Zhang, S.3
Bohrer, A.4
Ma, Z.5
Turk, J.6
-
39
-
-
0037196713
-
Delta6-, stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations
-
Ramanadham S, Zhang S, Ma Z, Wohltmann M, Bohrer A, Hsu FF, Turk J. 2002. Delta6-, stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations. Biochim Biophys Acta 1580:40-56.
-
(2002)
Biochim Biophys Acta
, vol.1580
, pp. 40-56
-
-
Ramanadham, S.1
Zhang, S.2
Ma, Z.3
Wohltmann, M.4
Bohrer, A.5
Hsu, F.F.6
Turk, J.7
-
40
-
-
33751507676
-
Adipose tissue, hepatic, and skeletal muscle insulin sensitivity in extremely obese subjects with acanthosis nigricans
-
Reeds DN, Stuart CA, Perez O, Klein S. 2006. Adipose tissue, hepatic, and skeletal muscle insulin sensitivity in extremely obese subjects with acanthosis nigricans. Metabolism 55:1658-1663.
-
(2006)
Metabolism
, vol.55
, pp. 1658-1663
-
-
Reeds, D.N.1
Stuart, C.A.2
Perez, O.3
Klein, S.4
-
41
-
-
12144291143
-
A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli
-
Roduit R, Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Masse F, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M. 2004. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. Diabetes 53:1007-1019.
-
(2004)
Diabetes
, vol.53
, pp. 1007-1019
-
-
Roduit, R.1
Nolan, C.2
Alarcon, C.3
Moore, P.4
Barbeau, A.5
Delghingaro-Augusto, V.6
Przybykowski, E.7
Morin, J.8
Masse, F.9
Massie, B.10
Ruderman, N.11
Rhodes, C.12
Poitout, V.13
Prentki, M.14
-
42
-
-
0037093532
-
Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: Effects on cell metabolism and insulin secretion
-
Rubi B, Antinozzi PA, Herrero L, Ishihara H, Asins G, Serra D, Wollheim CB, Maechler P, Hegardt FG. 2002. Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: Effects on cell metabolism and insulin secretion. Biochem J 364:219-226.
-
(2002)
Biochem J
, vol.364
, pp. 219-226
-
-
Rubi, B.1
Antinozzi, P.A.2
Herrero, L.3
Ishihara, H.4
Asins, G.5
Serra, D.6
Wollheim, C.B.7
Maechler, P.8
Hegardt, F.G.9
-
43
-
-
0032861252
-
Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells
-
Segall L, Lameloise N, Assimacopoulos-Jeannet F, Roche E, Corkey P, Thumelin S, Corkey BE, Prentki M. 1999. Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells. Am J Physiol 277:E521-E528.
-
(1999)
Am J Physiol
, vol.277
-
-
Segall, L.1
Lameloise, N.2
Assimacopoulos-Jeannet, F.3
Roche, E.4
Corkey, P.5
Thumelin, S.6
Corkey, B.E.7
Prentki, M.8
-
44
-
-
0029888870
-
Essentiality of circulating fatty acids for glucosestimulated insulin secretion in the fasted rat
-
Stein DT, Esser V, Stevenson BE, Lane KE, Whiteside JH, Daniels MB, Chen S, McGarry JD. 1996. Essentiality of circulating fatty acids for glucosestimulated insulin secretion in the fasted rat. J Clin Invest 97:2728-2735.
-
(1996)
J Clin Invest
, vol.97
, pp. 2728-2735
-
-
Stein, D.T.1
Esser, V.2
Stevenson, B.E.3
Lane, K.E.4
Whiteside, J.H.5
Daniels, M.B.6
Chen, S.7
McGarry, J.D.8
-
45
-
-
36049000864
-
Pancreatic fat content and beta-cell function in men with and without type 2 diabetes
-
Tushuizen ME, Bunck MC, Pouwels PJ, Bontemps S, van Waesberghe JH, Schindhelm RK, Mari A, Heine RJ, Diamant M. 2007. Pancreatic fat content and beta-cell function in men with and without type 2 diabetes. Diabetes Care 30:2916-2921.
-
(2007)
Diabetes Care
, vol.30
, pp. 2916-2921
-
-
Tushuizen, M.E.1
Bunck, M.C.2
Pouwels, P.J.3
Bontemps, S.4
van Waesberghe, J.H.5
Schindhelm, R.K.6
Mari, A.7
Heine, R.J.8
Diamant, M.9
-
46
-
-
1342286820
-
Monounsaturated fatty acids protect against beta-cell apoptosis induced by saturated fatty acids, serum withdrawal or cytokine exposure
-
Welters HJ, Tadayyon M, Scarpello JH, Smith SA, Morgan NG. 2004. Monounsaturated fatty acids protect against beta-cell apoptosis induced by saturated fatty acids, serum withdrawal or cytokine exposure. FEBS Lett 560:103-108.
-
(2004)
FEBS Lett
, vol.560
, pp. 103-108
-
-
Welters, H.J.1
Tadayyon, M.2
Scarpello, J.H.3
Smith, S.A.4
Morgan, N.G.5
-
47
-
-
0028268936
-
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
-
Zhou YP, Grill VE. 1994. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93:870-876.
-
(1994)
J Clin Invest
, vol.93
, pp. 870-876
-
-
Zhou, Y.P.1
Grill, V.E.2
-
48
-
-
0029787332
-
Inhibitory effects of fatty acids on glucoseregulated B-cell function: Association with increased islet triglyceride stores and altered effect of fatty acid oxidation on glucose metabolism
-
Zhou YP, Ling ZC, Grill VE. 1996. Inhibitory effects of fatty acids on glucoseregulated B-cell function: Association with increased islet triglyceride stores and altered effect of fatty acid oxidation on glucose metabolism. Metabolism 45:981-986.
-
(1996)
Metabolism
, vol.45
, pp. 981-986
-
-
Zhou, Y.P.1
Ling, Z.C.2
Grill, V.E.3
|