-
1
-
-
33645304322
-
Imidazolium receptors for the recognition of anions [J]
-
YOON J, KIM SK, SINGH NJ, et al. Imidazolium receptors for the recognition of anions [J]. Chem Soc Rev, 2006, 35 (4): 355-360.
-
(2006)
Chem Soc Rev
, vol.35
, Issue.4
, pp. 355-360
-
-
YOON, J.1
KIM, S.K.2
SINGH, N.J.3
-
2
-
-
33750501769
-
Chiral imidazole metalloenzyme models: Synthesis and enantioselective hydrolysis for α-amino acid esters [J]
-
JIANG HY, ZHOU CH, LUO K, et al. Chiral imidazole metalloenzyme models: Synthesis and enantioselective hydrolysis for α-amino acid esters [J]. J Mol Cat A: Chem, 2006,260 (1-2): 288-294.
-
(2006)
J Mol Cat A: Chem
, vol.260
, Issue.1-2
, pp. 288-294
-
-
JIANG, H.Y.1
ZHOU, C.H.2
LUO, K.3
-
4
-
-
1942438208
-
Propargylic sulfones possessing a 2-nitroimidazole function: Novel hypoxic-cell radio-sensitizers with intracellular non-protein thiol depletion ability [J]
-
TANABE K, KOJIMA R, HATTA H, et al. Propargylic sulfones possessing a 2-nitroimidazole function: novel hypoxic-cell radio-sensitizers with intracellular non-protein thiol depletion ability [J]. Bioorg Med Chem Lett, 2004,14 (10): 2633-2635.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.10
, pp. 2633-2635
-
-
TANABE, K.1
KOJIMA, R.2
HATTA, H.3
-
5
-
-
28544433163
-
Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3[J]
-
MILLER TJ, SCHNEIDER RJ, MILLER JA, et al. Photoreceptor cell apoptosis induced by the 2-nitroimidazole radiosensitizer, CI-1010, is mediated by p53-linked activation of caspase-3[J]. Neurotoxicology, 2006,27 (1): 44-59.
-
(2006)
Neurotoxicology
, vol.27
, Issue.1
, pp. 44-59
-
-
MILLER, T.J.1
SCHNEIDER, R.J.2
MILLER, J.A.3
-
6
-
-
1542314927
-
Synthesis of a novel nitroimidazole-spermidine derivative as a tumor-targeted hypoxia-selective cytotoxin[J]
-
PAPADOPOULOU MV, ROSENZWEIG HS, BLOOMER WD. Synthesis of a novel nitroimidazole-spermidine derivative as a tumor-targeted hypoxia-selective cytotoxin[J]. Bioorg Med Chem Lett, 2004,14(6): 1519-1522.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.6
, pp. 1519-1522
-
-
PAPADOPOULOU, M.V.1
ROSENZWEIG, H.S.2
BLOOMER, W.D.3
-
7
-
-
4444317357
-
Angiogenesis inhibitor TX-1898: Syntheses of the enantiomers of sterically diverse haloacetylearbamoyl-2-nitroimidazole hypoxic cell radiosensitizers[J]
-
JIN CZ, NAGASAWA H, SHIMAMURA M, et al. Angiogenesis inhibitor TX-1898: syntheses of the enantiomers of sterically diverse haloacetylearbamoyl-2-nitroimidazole hypoxic cell radiosensitizers[J]. Bioorg Med Chem, 2004,12(18): 4917-4927.
-
(2004)
Bioorg Med Chem
, vol.12
, Issue.18
, pp. 4917-4927
-
-
JIN, C.Z.1
NAGASAWA, H.2
SHIMAMURA, M.3
-
8
-
-
4544333863
-
Synthesis and biological evaluation of 1-benzyl-5-(3-biphenyl-2-yl-propyl)-1H-imidazole as novel farnesyl transferase inhibitor [J]
-
LIN NH, WANG L, WANG XL, et al. Synthesis and biological evaluation of 1-benzyl-5-(3-biphenyl-2-yl-propyl)-1H-imidazole as novel farnesyl transferase inhibitor [J]. Bioorg Med Chem Lett, 2004,14 (20): 5057-5062.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.20
, pp. 5057-5062
-
-
LIN, N.H.1
WANG, L.2
WANG, X.L.3
-
9
-
-
20144388523
-
Design, synthesis and activity of achiral analogs of 2 -quinolones and indoles as non-thiol farnesyl transferase inhibitors[J]
-
LI Q, WOODS KW, WANG WB, et al. Design, synthesis and activity of achiral analogs of 2 -quinolones and indoles as non-thiol farnesyl transferase inhibitors[J]. Bioorg Med Chem Lett, 2005, 15(8): 2033-2039.
-
(2005)
Bioorg Med Chem Lett
, vol.15
, Issue.8
, pp. 2033-2039
-
-
LI, Q.1
WOODS, K.W.2
WANG, W.B.3
-
10
-
-
0037424681
-
Aryl tetrahydropyridine inhibitors of farnesyl transferase: Bioavailable analogues with improved cellular potency[J]
-
GWALTNEY SL 2ND, O'CONNOR SJ, NELSON LT, et al. Aryl tetrahydropyridine inhibitors of farnesyl transferase: bioavailable analogues with improved cellular potency[J]. Bioorg Med Chem Lett, 2003, 13(7): 1363-1366.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, Issue.7
, pp. 1363-1366
-
-
GWALTNEY 2ND, S.L.1
O'CONNOR, S.J.2
NELSON, L.T.3
-
11
-
-
12444299958
-
Discovery of potent imidazole and cyanophenyl containing farnesyl transferase inhibitors with improved oral bioavailability[J]
-
TONG YS, LIN NH, WANG L, et al. Discovery of potent imidazole and cyanophenyl containing farnesyl transferase inhibitors with improved oral bioavailability[J]. Bioorg Med Chem Lett, 2003, 13(9): 1571-1574.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, Issue.9
, pp. 1571-1574
-
-
TONG, Y.S.1
LIN, N.H.2
WANG, L.3
-
12
-
-
34248177357
-
Impact on farnesyl transferase inhibition of 4-chlorophenyl moietyreplacement in the Zarnestra series [J]
-
ANGIBAUD P, MEBELLEC L, MEYER C, et al. Impact on farnesyl transferase inhibition of 4-chlorophenyl moietyreplacement in the Zarnestra series [J]. Eur J Med Chem, 2007, 42 (5): 702-714.
-
(2007)
Eur J Med Chem
, vol.42
, Issue.5
, pp. 702-714
-
-
ANGIBAUD, P.1
MEBELLEC, L.2
MEYER, C.3
-
13
-
-
5344263089
-
Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyl transferase inhibitors[J]
-
LI Q, CLAIBORNE A, LI T M, et al. Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyl transferase inhibitors[J]. Bioorg Med Chem Lett, 2004,14(21): 5367-5370.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.21
, pp. 5367-5370
-
-
LI, Q.1
CLAIBORNE, A.2
LI, T.M.3
-
14
-
-
0037424690
-
Novel and selective imidazole-containing biphenyl inhibitors of protein farnesyl transferase [J]
-
CURTIN ML, FLORJANCIC AS, COHEN J, et al. Novel and selective imidazole-containing biphenyl inhibitors of protein farnesyl transferase [J]. Bioorg Med Chem Lett, 2003, 13 (7): 1367-1371.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, Issue.7
, pp. 1367-1371
-
-
CURTIN, M.L.1
FLORJANCIC, A.S.2
COHEN, J.3
-
15
-
-
8644276405
-
Synthesis and biological evaluation of 4-imidazolylflavans as nonsteroidal aromatase inhibitors[J]
-
CHRISTELLE P, SAMIR Y, CATHERINE F, et al. Synthesis and biological evaluation of 4-imidazolylflavans as nonsteroidal aromatase inhibitors[J]. Bioorg Chem, 2004,32(6): 494-503.
-
(2004)
Bioorg Chem
, vol.32
, Issue.6
, pp. 494-503
-
-
CHRISTELLE, P.1
SAMIR, Y.2
CATHERINE, F.3
-
16
-
-
19444374982
-
Synthesis and characterization of azole isoflavone inhibitors of aromatase [J]
-
HACKETT JC, KIM YW, SU B, et al. Synthesis and characterization of azole isoflavone inhibitors of aromatase [J]. Bioorg Hed Chem Lett, 2005 13 (2): 4063-4070.
-
(2005)
Bioorg Hed Chem Lett
, vol.13
, Issue.2
, pp. 4063-4070
-
-
HACKETT, J.C.1
KIM, Y.W.2
SU, B.3
-
17
-
-
34249930470
-
Targeting cytochrome P450 enzymes: A new approach in anti-cancer drug development[J]
-
BRUNO RD, NJAR VCO. Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development[J]. Bioorg Med Chem, 2007, 15(15): 5047-5060.
-
(2007)
Bioorg Med Chem
, vol.15
, Issue.15
, pp. 5047-5060
-
-
BRUNO, R.D.1
NJAR, V.C.O.2
-
18
-
-
11144354613
-
C17,20-lyase inhibitors I. Structure-based de novo design and SAR study of C17,20-lyase inhibitors[J]
-
MATSUANAGA N, KAKU T, ITOH F, et al. C17,20-lyase inhibitors I. Structure-based de novo design and SAR study of C17,20-lyase inhibitors[J]. Bioorg Med Chem, 2004,12 (9): 2251-2273.
-
(2004)
Bioorg Med Chem
, vol.12
, Issue.9
, pp. 2251-2273
-
-
MATSUANAGA, N.1
KAKU, T.2
ITOH, F.3
-
19
-
-
3242754330
-
C17,20-lyase inhibitors. Part 2: Design, synthesis and structure-activity relationships of (2-naphthylmethyl) -1H-imidazoles as novel C 17,20 -lyase inhibitors[J]
-
MATSUNAGA N, KAKU T, OJIDA A, et al. C17,20-lyase inhibitors. Part 2: Design, synthesis and structure-activity relationships of (2-naphthylmethyl) -1H-imidazoles as novel C 17,20 -lyase inhibitors[J]. Bioorg Med Chem, 2004, 12(16):4313-4136.
-
(2004)
Bioorg Med Chem
, vol.12
, Issue.16
, pp. 4313-4136
-
-
MATSUNAGA, N.1
KAKU, T.2
OJIDA, A.3
-
20
-
-
2642569934
-
Application of organic carbamates in drug design. Part 1: Anticancer agents-recent reports[J]
-
RAY S, CHATURVEDI D. Application of organic carbamates in drug design. Part 1: anticancer agents-recent reports[J]. Drugs Fut, 2004,29(4):343-357.
-
(2004)
Drugs Fut
, vol.29
, Issue.4
, pp. 343-357
-
-
RAY, S.1
CHATURVEDI, D.2
-
21
-
-
0037044112
-
Novel benzimidazole derivatives selectively inhibit endothelial cell growth and suppress angiogenesis in vitro and in vivo [J]
-
HORI A, IMAEDA Y, KUBO KJ, et al. Novel benzimidazole derivatives selectively inhibit endothelial cell growth and suppress angiogenesis in vitro and in vivo [J]. Cancer Lett, 2002, 183 (1): 53-60.
-
(2002)
Cancer Lett
, vol.183
, Issue.1
, pp. 53-60
-
-
HORI, A.1
IMAEDA, Y.2
KUBO, K.J.3
-
22
-
-
8544257047
-
Synthesis of C8-linked pyrrolo [2, 1-c] [1,4] benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity[J]
-
KAMAL A, RAMULU P, SRINIVAS O, et al. Synthesis of C8-linked pyrrolo [2, 1-c] [1,4] benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity[J]. Bioorg Med Chem Lett, 2004,14(18): 4791-4794.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.18
, pp. 4791-4794
-
-
KAMAL, A.1
RAMULU, P.2
SRINIVAS, O.3
-
23
-
-
1842426000
-
Some fused heterocyclic compounds as eukaryotic topoisomerase II inhibitors[J]
-
PINAR A, YURDAKUL P, YILDIZ I, et al. Some fused heterocyclic compounds as eukaryotic topoisomerase II inhibitors[J]. Biochem Biophys Res Commun, 2004,317(2): 670-674.
-
(2004)
Biochem Biophys Res Commun
, vol.317
, Issue.2
, pp. 670-674
-
-
PINAR, A.1
YURDAKUL, P.2
YILDIZ, I.3
-
24
-
-
33846914936
-
Synthesis of 3-(1H-benzimidazol-2-yl) -5-isoquinolin-4-yl pyrazolo [1,2-b] pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor[J]
-
HUANG S, LIN R H, YU Y, et al. Synthesis of 3-(1H-benzimidazol-2-yl) -5-isoquinolin-4-yl pyrazolo [1,2-b] pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor[J]. Bioorg Med Chem Lett, 2007,17(5): 1243-1245.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, Issue.5
, pp. 1243-1245
-
-
HUANG, S.1
LIN, R.H.2
YU, Y.3
-
25
-
-
33749258555
-
Novel imidazole-based combretastatin A-4 analogues: Evaluation of their in vitro antitumor activity and molecular modeling study of their binding to the colchicine site of tubulin[J]
-
FABIO B, SILVIA C, SUSANNA M, et al. Novel imidazole-based combretastatin A-4 analogues: evaluation of their in vitro antitumor activity and molecular modeling study of their binding to the colchicine site of tubulin[J]. Bioorg Med Chem Lett, 2006,16(22): 5757-5762.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, Issue.22
, pp. 5757-5762
-
-
FABIO, B.1
SILVIA, C.2
SUSANNA, M.3
-
26
-
-
0035913167
-
Synthesis and anticancer activity of novel chiral D-glucose derived bis-benzinvidazoles and analogues [J]
-
ZHOU CH, HASSENER A. Synthesis and anticancer activity of novel chiral D-glucose derived bis-benzinvidazoles and analogues [J]. Carbohydr Res, 2001,333(4): 313-326.
-
(2001)
Carbohydr Res
, vol.333
, Issue.4
, pp. 313-326
-
-
ZHOU, C.H.1
HASSENER, A.2
-
27
-
-
11144355069
-
Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors [J]
-
WHITE AW, CURTIN NJ, EASTMAN BW, et al. Potentiation of cytotoxic drug activity in human tumour cell lines, by amine-substituted 2-arylbenzimidazole-4-carboxamide PARP-1 inhibitors [J]. Bioorg Med Chem Lett, 2004,14(10): 2433-2437.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, Issue.10
, pp. 2433-2437
-
-
WHITE, A.W.1
CURTIN, N.J.2
EASTMAN, B.W.3
-
28
-
-
2642569934
-
Application of organic carbamates in drug design. Part 1: Anticancer agents-recent reports [J]
-
RAY S, CHATURVED D. Application of organic carbamates in drug design. Part 1: anticancer agents-recent reports [J]. Drugs Fut, 2004,29(4): 343-357.
-
(2004)
Drugs Fut
, vol.29
, Issue.4
, pp. 343-357
-
-
RAY, S.1
CHATURVED, D.2
-
29
-
-
35348909638
-
Selective guanosine binding and cytotoxicity of a benzimidazole derived dinickel complex[J]
-
CHEN ZF, WANG XY, ZHU YG, et al. Selective guanosine binding and cytotoxicity of a benzimidazole derived dinickel complex[J]. J Inorg Biochem, 2007,101(11-12): 1894-1902.
-
(2007)
J Inorg Biochem
, vol.101
, Issue.11-12
, pp. 1894-1902
-
-
CHEN, Z.F.1
WANG, X.Y.2
ZHU, Y.G.3
-
30
-
-
17944366919
-
Zoledronic acid: Pharmacologic profile of a potent bisphosphonate[J]
-
GREEN JR. Zoledronic acid: pharmacologic profile of a potent bisphosphonate[J]. J Org Chem, 2005, 690(10): 2439-2448.
-
(2005)
J Org Chem
, vol.690
, Issue.10
, pp. 2439-2448
-
-
GREEN, J.R.1
|