메뉴 건너뛰기




Volumn 7, Issue 1, 2010, Pages 1-7

An overview of IL-7 biology and its use in immunotherapy

Author keywords

Aging; IL 7; Immunotherapy

Indexed keywords

CD27 ANTIGEN; CD31 ANTIGEN; CD4 ANTIGEN; CD45RA ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR7; IMMUNOMODULATING AGENT; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT INTERLEUKIN 7;

EID: 77649169182     PISSN: 1547691X     EISSN: 1547691X     Source Type: Journal    
DOI: 10.3109/15476910903453296     Document Type: Conference Paper
Times cited : (84)

References (61)
  • 1
    • 0031587826 scopus 로고    scopus 로고
    • Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
    • Akashi, K., Kondo, M., vonFreedenJeffry, U., Murray, R., and Weissman, I. L. 1997. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89:1033-1041.
    • (1997) Cell , vol.89 , pp. 1033-1041
    • Akashi, K.1    Kondo, M.2    Von Freeden Jeffry, U.3    Murray, R.4    Weissman, I.L.5
  • 3
    • 0034292431 scopus 로고    scopus 로고
    • A profound deficiency in thymic progenitor cells in mice lacking Jak3
    • Baird, A. M., Lucas, J. A., and Berg, L. J. 2000. A profound deficiency in thymic progenitor cells in mice lacking Jak3. J. Immunol. 165:3680-3688.
    • (2000) J. Immunol. , vol.165 , pp. 3680-3688
    • Baird, A.M.1    Lucas, J.A.2    Berg, L.J.3
  • 4
    • 4544331713 scopus 로고    scopus 로고
    • Activation of PI3K is indispensable for IL-7-mediated viability, proliferation, glucose use, and growth of T-cell acute lymphoblastic leukemia cells
    • Barata, J. T., Silva, A., Brandao, J. G., Nadler, L. M., Cardoso, A. A., and Boussiotis, V. A. 2004. Activation of PI3K is indispensable for IL-7-mediated viability, proliferation, glucose use, and growth of T-cell acute lymphoblastic leukemia cells. J. Exp. Med. 200:659-669.
    • (2004) J. Exp. Med. , vol.200 , pp. 659-669
    • Barata, J.T.1    Silva, A.2    Brandao, J.G.3    Nadler, L.M.4    Cardoso, A.A.5    Boussiotis, V.A.6
  • 5
    • 0030791028 scopus 로고    scopus 로고
    • Distinct roles for signals relayed through the common cytokine receptor-γ chain and IL-7 receptor-α chain in natural T-cell development
    • Boesteanu, A., Silva, A. D., Nakajima, H., Leonard, W. J., Peschon, J. J., and Joyce, S. 1997. Distinct roles for signals relayed through the common cytokine receptor-γ chain and IL-7 receptor-α chain in natural T-cell development. J. Exp. Med. 186:331-336.
    • (1997) J. Exp. Med. , vol.186 , pp. 331-336
    • Boesteanu, A.1    Silva, A.D.2    Nakajima, H.3    Leonard, W.J.4    Peschon, J.J.5    Joyce, S.6
  • 7
    • 0343812092 scopus 로고    scopus 로고
    • IL-7 receptor and VDJ recombination: Trophic versus mechanistic actions
    • Candeias, S., Muegge, K., and Durum, S. K. 1997. IL-7 receptor and VDJ recombination: Trophic versus mechanistic actions. Immunity 6:501-508.
    • (1997) Immunity , vol.6 , pp. 501-508
    • Candeias, S.1    Muegge, K.2    Durum, S.K.3
  • 11
    • 3843124199 scopus 로고    scopus 로고
    • Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function
    • Chu, Y. W., Memon, S. A., Sharrow, S. O., Hakim, F. T., Eckhaus, M., Lucas, P. J., and Gress, R. E. 2004. Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function. Blood 104:1110-1119.
    • (2004) Blood , vol.104 , pp. 1110-1119
    • Chu, Y.W.1    Memon, S.A.2    Sharrow, S.O.3    Hakim, F.T.4    Eckhaus, M.5    Lucas, P.J.6    Gress, R.E.7
  • 12
    • 18644373047 scopus 로고    scopus 로고
    • PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
    • Dakic, A., Metcalf, D., Di Rago, L., Mifsud, S., Wu, L.,and Nutt, S. L. 2005. PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis. J. Exp. Med. 201:1487-1502.
    • (2005) J. Exp. Med. , vol.201 , pp. 1487-1502
    • Dakic, A.1    Metcalf, D.2    Di Rago, L.3    Mifsud, S.4    Wu, L.5    Nutt, S.L.6
  • 13
    • 26844492214 scopus 로고    scopus 로고
    • SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T-cells, limiting their autoimmune potential
    • Davey, G. M., Starr, R., Cornish, A. L., Burghardt, J. T., Alexander, W. S., Carbone, F. R., Surh, C. D., and Heath, W. R. 2005. SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T-cells, limiting their autoimmune potential. J. Exp. Med. 202:1099-1108.
    • (2005) J. Exp. Med. , vol.202 , pp. 1099-1108
    • Davey, G.M.1    Starr, R.2    Cornish, A.L.3    Burghardt, J.T.4    Alexander, W.S.5    Carbone, F.R.6    Surh, C.D.7    Heath, W.R.8
  • 14
    • 0028878330 scopus 로고
    • Lymphoid development in mice with a targeted deletion of the interleukin-2 receptor-γ Chain
    • Disanto, J. P., Muller, W., Guygrand, D., Fischer, A., and Rajewsky, K. 1995. Lymphoid development in mice with a targeted deletion of the interleukin-2 receptor-γ chain. Proc. Natl. Acad. Sci. USA 92:377-381.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 377-381
    • Disanto, J.P.1    Muller, W.2    Guygrand, D.3    Fischer, A.4    Rajewsky, K.5
  • 15
    • 0032441260 scopus 로고    scopus 로고
    • Interleukin-7 receptor control of T-cell receptor-γ gene rearrangement: Role of receptor-associated chains and locus accessibility
    • Durum, S. K., Candeias, S., Nakajima, H., Leonard, W. J., Baird, A. M., Berg, L. J., and Muegge, K. 1998. Interleukin-7 receptor control of T-cell receptor-γ gene rearrangement: Role of receptor-associated chains and locus accessibility. J. Exp. Med. 188:2233-2241.
    • (1998) J. Exp. Med. , vol.188 , pp. 2233-2241
    • Durum, S.K.1    Candeias, S.2    Nakajima, H.3    Leonard, W.J.4    Baird, A.M.5    Berg, L.J.6    Muegge, K.7
  • 18
    • 0028874974 scopus 로고
    • Interleukin-7 can induce the activation of Jak-1, Jak-3, and Stat-5 proteins in murine T-cells
    • Foxwell, B. M. J., Beadling, C., Guschin, D., Kerr, I., and Cantrell, D. 1995. Interleukin-7 can induce the activation of Jak-1, Jak-3, and Stat-5 proteins in murine T-cells. Eur. J. Immunol. 25:3041-3046.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3041-3046
    • Foxwell, B.M.J.1    Beadling, C.2    Guschin, D.3    Kerr, I.4    Cantrell, D.5
  • 20
    • 0035471754 scopus 로고    scopus 로고
    • Interleukin-7: Master regulator of peripheral T-cell homeostasis?
    • Fry, T. J., and Mackall, C. L. 2001. Interleukin-7: Master regulator of peripheral T-cell homeostasis?Trends Immunol. 22:564-571.
    • (2001) Trends Immunol. , vol.22 , pp. 564-571
    • Fry, T.J.1    MacKall, C.L.2
  • 21
    • 0027153201 scopus 로고
    • - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • -triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150:4244-4252.
    • (1993) J. Immunol. , vol.150 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 24
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B-cell stages in normal mouse bone marrow
    • Hardy, R. R., Carmack, C. E., Shinton, S. A., Kemp, J. D., and Hayakawa, K. 1991. Resolution and characterization of pro-B and pre-pro-B-cell stages in normal mouse bone marrow. J. Exp. Med. 173:1213-1225.
    • (1991) J. Exp. Med. , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 25
    • 38549096234 scopus 로고    scopus 로고
    • Shaping and reshaping CD8+ T-cell memory
    • Harty, J. T., and Badovinac, V. P. 2008. Shaping and reshaping CD8+ T-cell memory. Nat. Rev. Immunol. 8:107-119.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 107-119
    • Harty, J.T.1    Badovinac, V.P.2
  • 27
    • 40149099723 scopus 로고    scopus 로고
    • Critical roles of the PI3K/Akt signaling pathway in T-cell development
    • Juntilla, M. M., and Koretzky, G. A. 2008. Critical roles of the PI3K/Akt signaling pathway in T-cell development. Immunol. Lett. 116:104-110.
    • (2008) Immunol. Lett. , vol.116 , pp. 104-110
    • Juntilla, M.M.1    Koretzky, G.A.2
  • 29
    • 0346103729 scopus 로고    scopus 로고
    • A role for TCR affinity in regulating naive T-cell homeostasis
    • Kieper, W. C., Burghardt, J. T., and Surh, C. D. 2004. A role for TCR affinity in regulating naive T-cell homeostasis. J. Immunol. 172:40-44.
    • (2004) J. Immunol. , vol.172 , pp. 40-44
    • Kieper, W.C.1    Burghardt, J.T.2    Surh, C.D.3
  • 30
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo, M., Weissman, I. L., and Akashi, K. 1997. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91:661-672.
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 31
    • 34447281286 scopus 로고    scopus 로고
    • A role for "self" in T-cell activation
    • Krogsgaard, M., Juang, J., and Davis, M. M. 2007. A role for "self" in T-cell activation. Semin. Immunol. 19:236-244.
    • (2007) Semin. Immunol. , vol.19 , pp. 236-244
    • Krogsgaard, M.1    Juang, J.2    Davis, M.M.3
  • 32
    • 0033025703 scopus 로고    scopus 로고
    • Thymic selection by a single MHC/peptide ligand: Autoreactive T-cells are low-affinity cells
    • Lee, D. S., Ahn, C., Ernst, B., Sprent, J., and Surh, C. D. 1999. Thymic selection by a single MHC/peptide ligand: Autoreactive T-cells are low-affinity cells. Immunity 10:83-92.
    • (1999) Immunity , vol.10 , pp. 83-92
    • Lee, D.S.1    Ahn, C.2    Ernst, B.3    Sprent, J.4    Surh, C.D.5
  • 33
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by Il-2, Il-4, Il-7, Il-13, and Il-15
    • Lin, J. X., Migone, T. S., Tsang, M., Friedmann, M., Weatherbee, J. A., Zhou, L., Yamauchi, A., Bloom, E. T., Mietz, J., John, S., and Leonard, W. J. 1995. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by Il-2, Il-4, Il-7, Il-13, and Il-15. Immunity 2:331-339.
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.X.1    Migone, T.S.2    Tsang, M.3    Friedmann, M.4    Weatherbee, J.A.5    Zhou, L.6    Yamauchi, A.7    Bloom, E.T.8    Mietz, J.9    John, S.10    Leonard, W.J.11
  • 36
    • 0030726968 scopus 로고    scopus 로고
    • The common cytokine receptor-γ chain controls survival of γ T-cells
    • Malissen, M., Pereira, P., Gerber, D. J., Malissen, B., and DiSanto, J. P. 1997. The common cytokine receptor-γ chain controls survival ofγ T-cells. J. Exp. Med. 186:1277-1285.
    • (1997) J. Exp. Med. , vol.186 , pp. 1277-1285
    • Malissen, M.1    Pereira, P.2    Gerber, D.J.3    Malissen, B.4    Disanto, J.P.5
  • 38
    • 33846632842 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression: Intelligent design
    • Mazzucchelli, R., and Durum, S. K. 2007. Interleukin-7 receptor expression: Intelligent design. Nat. Rev. Immunol. 7:144-154.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 144-154
    • Mazzucchelli, R.1    Durum, S.K.2
  • 43
    • 67649976634 scopus 로고    scopus 로고
    • Functions of γc cytokines in immune homeostasis: Current and potential clinical applications
    • Overwijk, W. W., and Schluns, K. S. 2009. Functions of γc cytokines in immune homeostasis: Current and potential clinical applications. Clin. Immunol. 132:153-165.
    • (2009) Clin. Immunol. , vol.132 , pp. 153-165
    • Overwijk, W.W.1    Schluns, K.S.2
  • 44
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7Rα transcription by IL-7 and other pro-survival cytokines: A novel mechanism for maximizing IL-7-dependent T-cell survival
    • Park, J. H., Yu, Q., Erman, B., Appelbaum, J. S., Montoya-Durango, D., Grimes, H. L., and Singer, A. 2004. Suppression of IL7Rα transcription by IL-7 and other pro-survival cytokines: A novel mechanism for maximizing IL-7-dependent T-cell survival. Immunity 21:289-302.
    • (2004) Immunity , vol.21 , pp. 289-302
    • Park, J.H.1    Yu, Q.2    Erman, B.3    Appelbaum, J.S.4    Montoya-Durango, D.5    Grimes, H.L.6    Singer, A.7
  • 47
    • 0024332461 scopus 로고
    • Peripheral T-lymphocytes: Expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo
    • Rocha, B., Dautigny, N., and Pereira, P. 1989. Peripheral T-lymphocytes: Expansion potential and homeostatic regulation of pool sizes and CD4/CD8 ratios in vivo. Eur. J. Immunol. 19:905-911.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 905-911
    • Rocha, B.1    Dautigny, N.2    Pereira, P.3
  • 50
    • 0027258121 scopus 로고
    • Functional and phenotypic analysis of thymocytes in SCID mice. Evidence for functional response transitions before and after the SCID arrest point
    • Rothenberg, E. V., Chen, D., and Diamond, R. A. 1993. Functional and phenotypic analysis of thymocytes in SCID mice. Evidence for functional response transitions before and after the SCID arrest point. J. Immunol. 151:3530-3546.
    • (1993) J. Immunol. , vol.151 , pp. 3530-3546
    • Rothenberg, E.V.1    Chen, D.2    Diamond, R.A.3
  • 51
    • 0034689009 scopus 로고    scopus 로고
    • The interleukin 7 receptor is required for T-cell receptor-γ locus accessibility to the VDJ recombinase
    • Schlissel, M. S., Durum, S. D., and Muegge, K. 2000. The interleukin 7 receptor is required for T-cell receptor-γ locus accessibility to the VDJ recombinase. J. Exp. Med. 191:1045-1050.
    • (2000) J. Exp. Med. , vol.191 , pp. 1045-1050
    • Schlissel, M.S.1    Durum, S.D.2    Muegge, K.3
  • 52
    • 33846513615 scopus 로고    scopus 로고
    • The p85α regulatory subunit of class IA phosphoinositide 3-kinase regulates beta-selection in thymocyte development
    • Shiroki, F., Matsuda, S., Doi, T., Fujiwara, M., Mochizuki, Y., Kadowaki, T., Suzuki, H., and Koyasu, S. 2007. The p85α regulatory subunit of class IA phosphoinositide 3-kinase regulates beta-selection in thymocyte development. J. Immunol. 178:1349-1356.
    • (2007) J. Immunol. , vol.178 , pp. 1349-1356
    • Shiroki, F.1    Matsuda, S.2    Doi, T.3    Fujiwara, M.4    Mochizuki, Y.5    Kadowaki, T.6    Suzuki, H.7    Koyasu, S.8
  • 56
    • 57449097558 scopus 로고    scopus 로고
    • Homeostasis of naive and memory T-cells
    • Surh, C. D., and Sprent, J. 2008. Homeostasis of naive and memory T-cells. Immunity 29:848-862.
    • (2008) Immunity , vol.29 , pp. 848-862
    • Surh, C.D.1    Sprent, J.2
  • 57
    • 0034665901 scopus 로고    scopus 로고
    • Role of common cytokine receptor-γ chain- and Jak3-dependent signaling in the proliferation and survival of murine mast cells
    • Suzuki, K., Nakajima, H., Watanabe, N., Kagami, S., Suto, A., Saito, Y., Saito, T., and Iwamoto, I. 2000. Role of common cytokine receptor-γ chain- and Jak3-dependent signaling in the proliferation and survival of murine mast cells. Blood 96:2172-2180.
    • (2000) Blood , vol.96 , pp. 2172-2180
    • Suzuki, K.1    Nakajima, H.2    Watanabe, N.3    Kagami, S.4    Suto, A.5    Saito, Y.6    Saito, T.7    Iwamoto, I.8
  • 60
    • 31344480910 scopus 로고    scopus 로고
    • Cytokine signal transduction is suppressed in pre-selection double-positive thymocytes and restored by positive selection
    • Yu, Q., Park, J. H., Doan, L. L., Erman, B., Feigenbaum, L., and Singer, A. 2006. Cytokine signal transduction is suppressed in pre-selection double-positive thymocytes and restored by positive selection. J. Exp. Med. 203:165-175.
    • (2006) J. Exp. Med. , vol.203 , pp. 165-175
    • Yu, Q.1    Park, J.H.2    Doan, L.L.3    Erman, B.4    Feigenbaum, L.5    Singer, A.6
  • 61
    • 33745207614 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin in normal and pathogenic T-cell development and function
    • Ziegler, S. F., and Liu, Y. J. 2006. Thymic stromal lymphopoietin in normal and pathogenic T-cell development and function. Nat. Immunol. 7:709-714.
    • (2006) Nat. Immunol. , vol.7 , pp. 709-714
    • Ziegler, S.F.1    Liu, Y.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.