Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors

Arthritis and Rheumatism

Volumn 62, Issue 3, 2010, Pages 683-693

  Sacre, Sandra ^a   Medghalchi, Mino ^b   Gregory, Bernard ^b   Brennan, Fionula ^b   Williams, Richard ^b  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CITALOPRAM; COLLAGEN; FLUOXETINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 6; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; EX VIVO STUDY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PAW EDEMA; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIUM;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CITALOPRAM; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; FLUOXETINE; HUMANS; MACROPHAGES; MALE; MICE; MICE, INBRED DBA; SEROTONIN UPTAKE INHIBITORS; SYNOVIAL MEMBRANE; TOLL-LIKE RECEPTORS;

EID: 77649124410     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27304     Document Type: Article

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