Severe retinal degeneration caused by a novel rhodopsin mutation

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 2, 2010, Pages 1059-1065

  Liu, Haiquan ^a   Wang, Meng ^a   Xia, Chun Hong ^a   Du, Xin ^b   Flannery, John G ^a   Ridge, Kevin D ^c   Beutler, Bruce ^b   Gong, Xiaohua ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; RHODOPSIN; ETHYLNITROSOUREA;

A WAVE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B WAVE; CONTROLLED STUDY; DISEASE SEVERITY; DNA SEQUENCE; ELECTRORETINOGRAPHY; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; HISTOPATHOLOGY; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; LINKAGE ANALYSIS; MALE; MOUSE; MOUSE MUTANT; NONHUMAN; OPHTHALMOSCOPY; PATHOGENESIS; PHENOTYPE; PHOTORECEPTOR CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; RETINA BLOOD VESSEL; RETINA DEGENERATION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; WILD TYPE; ANIMAL; C57BL MOUSE; DOMINANT GENE; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PATHOPHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA MUTATIONAL ANALYSIS; ELECTRORETINOGRAPHY; ETHYLNITROSOUREA; GENES, DOMINANT; GENOME-WIDE ASSOCIATION STUDY; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OPHTHALMOSCOPY; PHENOTYPE; PHOTORECEPTOR CELLS, VERTEBRATE; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; RETINAL DEGENERATION; RHODOPSIN;

EID: 77449113158     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-3585     Document Type: Article

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