-
1
-
-
0027521914
-
Apoptosis: Final common pathway of photoreceptor death in rd, rs and rhodopsin mutant mice
-
Chang GQ, Hao Y, Wong F. Apoptosis: final common pathway of photoreceptor death in rd, rs and rhodopsin mutant mice. Neuron. 1993;11:595-605.
-
(1993)
Neuron
, vol.11
, pp. 595-605
-
-
Chang, G.Q.1
Hao, Y.2
Wong, F.3
-
3
-
-
4344565195
-
Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse
-
Hackam AS, Strom R, Liu D, et al. Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Invest Ophthalmol Vis Sci. 2004;45:2929-2942.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 2929-2942
-
-
Hackam, A.S.1
Strom, R.2
Liu, D.3
-
4
-
-
0033134010
-
Amelioration of retinal photic injury in albino rats by dimethylthiourea
-
Carmody RJ, McGowan AJ, Cotter TG. Amelioration of retinal photic injury in albino rats by dimethylthiourea. Exp Cell Res. 1999;248:520-530.
-
(1999)
Exp Cell Res
, vol.248
, pp. 520-530
-
-
Carmody, R.J.1
McGowan, A.J.2
Cotter, T.G.3
-
5
-
-
33744913540
-
Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death
-
Lohr HR, Kuntchithapautham K, Sharma AK, Rohrer B. Multiple, parallel cellular suicide mechanisms participate in photoreceptor cell death. Exp Eye Res. 2006;83:380-389.
-
(2006)
Exp Eye Res
, vol.83
, pp. 380-389
-
-
Lohr, H.R.1
Kuntchithapautham, K.2
Sharma, A.K.3
Rohrer, B.4
-
6
-
-
0025687417
-
Amelioration of retinal photic injury in albino rats by dimethylthiourea
-
Lam S, Tso MO, Gurne DH. Amelioration of retinal photic injury in albino rats by dimethylthiourea. Arch Ophthalmol. 1990;108:1751-1757.
-
(1990)
Arch Ophthalmol
, vol.108
, pp. 1751-1757
-
-
Lam, S.1
Tso, M.O.2
Gurne, D.H.3
-
7
-
-
0032925854
-
Functional protection of photoreceptors from light-induced damage by dimethylthiourea and Ginkgo biloba extract
-
Ranchon I, Gorrand JM, Cluzel J, Droy-Lefaix MT, Doly M. Functional protection of photoreceptors from light-induced damage by dimethylthiourea and Ginkgo biloba extract. Invest Ophthalmol Vis Sci. 1999;40:1191-1199.
-
(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 1191-1199
-
-
Ranchon, I.1
Gorrand, J.M.2
Cluzel, J.3
Droy-Lefaix, M.T.4
Doly, M.5
-
8
-
-
35248831880
-
Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa
-
Komeima K, Rogers BS, Campochiaro PA. Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa. J Cell Physiol. 2007;213:809-815.
-
(2007)
J Cell Physiol
, vol.213
, pp. 809-815
-
-
Komeima, K.1
Rogers, B.S.2
Campochiaro, P.A.3
-
9
-
-
0037407743
-
Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors
-
Rotstein NP, Politi LE, German OL, Girotti R. Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors. Invest Ophthalmol Vis Sci. 2003;44:2252-2259.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 2252-2259
-
-
Rotstein, N.P.1
Politi, L.E.2
German, O.L.3
Girotti, R.4
-
10
-
-
0034733910
-
Sphingosine-1-phosphate: Signaling inside and out
-
Spiegel S, Milstien S. Sphingosine-1-phosphate: signaling inside and out. FEBS Lett. 2000;476:55-57.
-
(2000)
FEBS Lett
, vol.476
, pp. 55-57
-
-
Spiegel, S.1
Milstien, S.2
-
11
-
-
0028537064
-
The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation
-
Kolesnick RN, Haimovitz-Friedman A, Fuks Z. The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation. Biochem Cell Biol. 1994;72:471-474.
-
(1994)
Biochem Cell Biol
, vol.72
, pp. 471-474
-
-
Kolesnick, R.N.1
Haimovitz-Friedman, A.2
Fuks, Z.3
-
12
-
-
66349086742
-
Bioactive sphingolipids: Metabolism and function
-
Bartke N, Hannun YA. Bioactive sphingolipids: metabolism and function. J Lipid Res. 2008;50:S91-S96.
-
(2008)
J Lipid Res
, vol.50
-
-
Bartke, N.1
Hannun, Y.A.2
-
13
-
-
38549152194
-
Principles of bioactive lipid signalling
-
Hannun YA, Obeid LM. Principles of bioactive lipid signalling. Nat Rev Mol Cell Biol. 2008;9:139-150.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
14
-
-
0030448021
-
Functions of ceramide in coordinating cellular responses to stress
-
Hannun YA. Functions of ceramide in coordinating cellular responses to stress. Science. 1996;274:1855-1859.
-
(1996)
Science
, vol.274
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
16
-
-
0037135626
-
The ceramide-centric universe of lipidmediated cell regulation: Stress encounters of the lipid kind
-
Hannun YA, Obeid LM. The ceramide-centric universe of lipidmediated cell regulation: stress encounters of the lipid kind. J Biol Chem. 2002;277:25847-25850.
-
(2002)
J Biol Chem
, vol.277
, pp. 25847-25850
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
17
-
-
0029148660
-
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
-
Bose R, Verheij M, Haimovitz-Friedman A, Scott K, Fuks Z, Kolesnick RN. Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell. 1995;82:405-414.
-
(1995)
Cell
, vol.82
, pp. 405-414
-
-
Bose, R.1
Verheij, M.2
Haimovitz-Friedman, A.3
Scott, K.4
Fuks, Z.5
Kolesnick, R.N.6
-
18
-
-
0034859079
-
Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicintreated human breast carcinoma cells
-
Gouaze V, Mirault ME, Carpentier S, Salvayre R, Levade T, Andrieu-Abadie N. Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicintreated human breast carcinoma cells. Mol Pharmacol. 2001;60:488-496.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 488-496
-
-
Gouaze, V.1
Mirault, M.E.2
Carpentier, S.3
Salvayre, R.4
Levade, T.5
Andrieu-Abadie, N.6
-
19
-
-
0029101644
-
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
-
Zamzami N, Marchetti P, Castedo M, et al. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med. 1995;182:367-377.
-
(1995)
J Exp Med
, vol.182
, pp. 367-377
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
-
20
-
-
0030066567
-
Ceramide induces apoptosis in cultured mesencephalic neurons
-
Brugg B, Michel PP, Agid Y, Ruberg M. Ceramide induces apoptosis in cultured mesencephalic neurons. J Neurochem. 1996;66:733-739.
-
(1996)
J Neurochem
, vol.66
, pp. 733-739
-
-
Brugg, B.1
Michel, P.P.2
Agid, Y.3
Ruberg, M.4
-
21
-
-
0029987190
-
Staurosporine induces programmed cell death in embryonic neurons and activation of the ceramide pathway
-
Wiesner DA, Dawson G. Staurosporine induces programmed cell death in embryonic neurons and activation of the ceramide pathway. J Neurochem. 1996;66:1418-1425.
-
(1996)
J Neurochem
, vol.66
, pp. 1418-1425
-
-
Wiesner, D.A.1
Dawson, G.2
-
22
-
-
0037203316
-
Sphingosine in apoptosis signaling
-
Cuvillier O. Sphingosine in apoptosis signaling. Biochim Biophys Acta. 2002;1585:153-162.
-
(2002)
Biochim Biophys Acta
, vol.1585
, pp. 153-162
-
-
Cuvillier, O.1
-
23
-
-
0028900748
-
Induction of apoptosis by sphingosine in human leukemic HL-60 cells: A possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation
-
Ohta H, Sweeney EA, Masamune A, Yatomi Y, Hakomori S, Igarashi Y. Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation. Cancer Res. 1995;55:691-697.
-
(1995)
Cancer Res
, vol.55
, pp. 691-697
-
-
Ohta, H.1
Sweeney, E.A.2
Masamune, A.3
Yatomi, Y.4
Hakomori, S.5
Igarashi, Y.6
-
24
-
-
0034717184
-
Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells
-
Cuvillier O, Edsall L, Spiegel S. Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells. J Biol Chem. 2000;275:15691-15700.
-
(2000)
J Biol Chem
, vol.275
, pp. 15691-15700
-
-
Cuvillier, O.1
Edsall, L.2
Spiegel, S.3
-
25
-
-
0037436579
-
Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration
-
Acharya U, Patel S, Koundakjian E, Nagashima K, Han X, Acharya JK. Modulating sphingolipid biosynthetic pathway rescues photoreceptor degeneration. Science. 2003;299:1740-1743.
-
(2003)
Science
, vol.299
, pp. 1740-1743
-
-
Acharya, U.1
Patel, S.2
Koundakjian, E.3
Nagashima, K.4
Han, X.5
Acharya, J.K.6
-
26
-
-
0346373649
-
Mutation of CERKL, a novel human ceramide kinase gene, causes autosomal recessive retinitis pigmentosa (RP26)
-
Tuson M, Marfany G, Gonzalez-Duarte R. Mutation of CERKL, a novel human ceramide kinase gene, causes autosomal recessive retinitis pigmentosa (RP26). Am J Hum Genet. 2004;74:128-138.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 128-138
-
-
Tuson, M.1
Marfany, G.2
Gonzalez-Duarte, R.3
-
27
-
-
59249100880
-
Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress
-
Tuson M, Garanto A, González-Duarte R, Marfany G. Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress. Mol Vis. 2009;15:168-180.
-
(2009)
Mol Vis
, vol.15
, pp. 168-180
-
-
Tuson, M.1
Garanto, A.2
González-Duarte, R.3
Marfany, G.4
-
29
-
-
33746874469
-
Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells
-
Sanvicens N, Cotter TG. Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells. J Neurochem. 2006;98:1432-1444.
-
(2006)
J Neurochem
, vol.98
, pp. 1432-1444
-
-
Sanvicens, N.1
Cotter, T.G.2
-
30
-
-
1242296816
-
Ceramidase expression facilitates membrane turnover and endocytosis of rhodopsin in photoreceptors
-
Acharya U, Mowen MB, Nagashima K, Acharya JK. Ceramidase expression facilitates membrane turnover and endocytosis of rhodopsin in photoreceptors. Proc Natl Acad Sci U S A. 2004;101:1922-1926.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1922-1926
-
-
Acharya, U.1
Mowen, M.B.2
Nagashima, K.3
Acharya, J.K.4
-
31
-
-
0029888029
-
Heterologous retinal cultured neurons and cell adhesion molecules induce clustering of acetylcholine receptors and polynucleation in mouse muscle BC3H-1 clonal cell line
-
Politi LE, Bouzat C, de los Santos EB, Barrantes FJ. Heterologous retinal cultured neurons and cell adhesion molecules induce clustering of acetylcholine receptors and polynucleation in mouse muscle BC3H-1 clonal cell line. J Neurosci Res. 1996;43:639-651.
-
(1996)
J Neurosci Res
, vol.43
, pp. 639-651
-
-
Politi, L.E.1
Bouzat, C.2
de los Santos, E.B.3
Barrantes, F.J.4
-
32
-
-
0030005641
-
Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro
-
Rotstein NP, Aveldaño MI, Barrantes FJ, Politi LE. Docosahexaenoic acid is required for the survival of rat retinal photoreceptors in vitro. J Neurochem. 1996;66:1851-1859.
-
(1996)
J Neurochem
, vol.66
, pp. 1851-1859
-
-
Rotstein, N.P.1
Aveldaño, M.I.2
Barrantes, F.J.3
Politi, L.E.4
-
33
-
-
0020412918
-
Regulation of neurite growth in purified retina neuronal cultures: Effects of PNPF, a substratum-bound, neurite-promoting factor
-
Adler R. Regulation of neurite growth in purified retina neuronal cultures: effects of PNPF, a substratum-bound, neurite-promoting factor. J Neurosci Res. 1982;8:165-177.
-
(1982)
J Neurosci Res
, vol.8
, pp. 165-177
-
-
Adler, R.1
-
34
-
-
0027327212
-
Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide: Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B
-
Dbaibo GS, Obeid LM, Hannun YA. Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide: dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B. J Biol Chem. 1993;268:17762-17766.
-
(1993)
J Biol Chem
, vol.268
, pp. 17762-17766
-
-
Dbaibo, G.S.1
Obeid, L.M.2
Hannun, Y.A.3
-
35
-
-
17544366509
-
(1S,2R)-D-erythro-2-(Nmyristoylamino)-1-phenyl-1-propanol as an inhibitor of ceramidase
-
Bielawska A, Greenberg MS, Perry D, et al. (1S,2R)-D-erythro-2-(Nmyristoylamino)-1-phenyl-1-propanol as an inhibitor of ceramidase. J Biol Chem. 1996;271:12646-12654.
-
(1996)
J Biol Chem
, vol.271
, pp. 12646-12654
-
-
Bielawska, A.1
Greenberg, M.S.2
Perry, D.3
-
36
-
-
0024388154
-
Differential susceptibility of isolated mouse retinal neurons and photoreceptors to kainic acid toxicity: In vitro studies
-
Abrams L, Politi L, Adler R. Differential susceptibility of isolated mouse retinal neurons and photoreceptors to kainic acid toxicity: in vitro studies. Invest Ophthalmol Vis Sci. 1989;30:2300-2308.
-
(1989)
Invest Ophthalmol Vis Sci
, vol.30
, pp. 2300-2308
-
-
Abrams, L.1
Politi, L.2
Adler, R.3
-
37
-
-
0032189348
-
Proteasome inhibitors: Valuable new tools for cell biologists
-
Lee DH, Goldberg AL. Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol. 1998;8:397-403.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 397-403
-
-
Lee, D.H.1
Goldberg, A.L.2
-
38
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37:911-917.
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
39
-
-
0037066697
-
Apoptotic effect of sphingosine 1-phosphate and increased sphingosine 1-phosphate hydrolysis on mesangial cells cultured at low cell density
-
Gennero I, Fauvel J, Nieto M, et al. Apoptotic effect of sphingosine 1-phosphate and increased sphingosine 1-phosphate hydrolysis on mesangial cells cultured at low cell density. J Biol Chem. 2002;277:12724-12734.
-
(2002)
J Biol Chem
, vol.277
, pp. 12724-12734
-
-
Gennero, I.1
Fauvel, J.2
Nieto, M.3
-
40
-
-
0034761025
-
Effect of GDNF on neuroblast proliferation and photoreceptor survival: Additive protection with docosahexaenoic acid
-
Politi LE, Rotstein NP, Carri NG. Effect of GDNF on neuroblast proliferation and photoreceptor survival: additive protection with docosahexaenoic acid. Invest Ophthalmol Vis Sci. 2001;42:3008-3015.
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 3008-3015
-
-
Politi, L.E.1
Rotstein, N.P.2
Carri, N.G.3
-
41
-
-
0035165071
-
Effects of docosahexaenoic acid on retinal development: Cellular and molecular aspects
-
Politi LE, Rotstein NP, Carri N. Effects of docosahexaenoic acid on retinal development: cellular and molecular aspects. Lipids. 2001;36:927-935.
-
(2001)
Lipids
, vol.36
, pp. 927-935
-
-
Politi, L.E.1
Rotstein, N.P.2
Carri, N.3
-
42
-
-
0019311061
-
Monoclonal antibodies which recognize different cell types in the rat retina
-
Barnstable CJ. Monoclonal antibodies which recognize different cell types in the rat retina. Nature. 1980;286:231-235.
-
(1980)
Nature
, vol.286
, pp. 231-235
-
-
Barnstable, C.J.1
-
44
-
-
0035090339
-
Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicininduced apoptosis of MCF7 breast adenocarcinoma cells
-
Cuvillier O, Nava VE, Murthy SK, et al. Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicininduced apoptosis of MCF7 breast adenocarcinoma cells. Cell Death Differ. 2001;8:162-171.
-
(2001)
Cell Death Differ
, vol.8
, pp. 162-171
-
-
Cuvillier, O.1
Nava, V.E.2
Murthy, S.K.3
-
45
-
-
38449115096
-
Lutein and zeaxanthin protect photoreceptors from apoptosis induced by oxidative stress: Relation with docosahexaenoic acid
-
Chucair AJ, Rotstein NP, Sangiovanni JP, During A, Chew EY, Politi LE. Lutein and zeaxanthin protect photoreceptors from apoptosis induced by oxidative stress: relation with docosahexaenoic acid. Invest Ophthalmol Vis Sci. 2007;48:5168-5177.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 5168-5177
-
-
Chucair, A.J.1
Rotstein, N.P.2
Sangiovanni, J.P.3
During, A.4
Chew, E.Y.5
Politi, L.E.6
-
46
-
-
0030807556
-
Apoptosis of retinal photoreceptors during development in vitro: Protective effect of docosahexaenoic acid
-
Rotstein NP, Aveldaño MI, Barrantes FJ, Roccamo AM, Politi LE. Apoptosis of retinal photoreceptors during development in vitro: protective effect of docosahexaenoic acid. J Neurochem. 1997;2:504-513.
-
(1997)
J Neurochem
, vol.2
, pp. 504-513
-
-
Rotstein, N.P.1
Aveldaño, M.I.2
Barrantes, F.J.3
Roccamo, A.M.4
Politi, L.E.5
-
47
-
-
33645801577
-
Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: Modulation of sphingolipid levels and the induction of apoptosis
-
Taha TA, Kitatani K, El-Alwani M, Bielawski J, Hannun YA, Obeid LM. Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis. FASEB J. 2006;20:482-484.
-
(2006)
FASEB J
, vol.20
, pp. 482-484
-
-
Taha, T.A.1
Kitatani, K.2
El-Alwani, M.3
Bielawski, J.4
Hannun, Y.A.5
Obeid, L.M.6
-
48
-
-
27744547965
-
Sphingosine kinase1 and Sphingosine kinase2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism
-
Maceyka M, Sankala H, Hait NC, et al. Sphingosine kinase1 and Sphingosine kinase2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. J Biol Chem. 2005;280:37118-37129.
-
(2005)
J Biol Chem
, vol.280
, pp. 37118-37129
-
-
Maceyka, M.1
Sankala, H.2
Hait, N.C.3
-
50
-
-
0033974782
-
Ceramide in the eukaryotic stress response
-
Hannun YA, Luberto C. Ceramide in the eukaryotic stress response. Trends Cell Biol. 2000;10:73-80.
-
(2000)
Trends Cell Biol
, vol.10
, pp. 73-80
-
-
Hannun, Y.A.1
Luberto, C.2
-
51
-
-
33747603712
-
Sphingosine and ceramide signalling in apoptosis
-
Woodcock J. Sphingosine and ceramide signalling in apoptosis. IUBMB Life. 2006;58:462-466.
-
(2006)
IUBMB Life
, vol.58
, pp. 462-466
-
-
Woodcock, J.1
-
52
-
-
0027973628
-
A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils
-
Ohta H, Yatomi Y, Sweeney EA, Hakomori S, Igarashi Y. A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils. FEBS Lett. 1994;355:267-270.
-
(1994)
FEBS Lett
, vol.355
, pp. 267-270
-
-
Ohta, H.1
Yatomi, Y.2
Sweeney, E.A.3
Hakomori, S.4
Igarashi, Y.5
-
53
-
-
0032549509
-
Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide
-
Sweeney EA, Inokuchi J, Igarashi Y. Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide. FEBS Lett. 1998;425:61-65.
-
(1998)
FEBS Lett
, vol.425
, pp. 61-65
-
-
Sweeney, E.A.1
Inokuchi, J.2
Igarashi, Y.3
-
54
-
-
9344268261
-
Sphingosine mediates FTY720-induced apoptosis in LLC-PK1 cells
-
Lee WJ, Yoo HS, Suh PG, Oh S, Lim JS, Lee YM. Sphingosine mediates FTY720-induced apoptosis in LLC-PK1 cells. Exp Mol Med. 2004;36:420-427.
-
(2004)
Exp Mol Med
, vol.36
, pp. 420-427
-
-
Lee, W.J.1
Yoo, H.S.2
Suh, P.G.3
Oh, S.4
Lim, J.S.5
Lee, Y.M.6
-
55
-
-
6944241423
-
Sphingosine-dependent apoptosis: A unified concept based on multiple mechanisms operating in concert
-
Suzuki E, Handa K, Toledo MS, Hakomori S. Sphingosine-dependent apoptosis: a unified concept based on multiple mechanisms operating in concert. Proc Natl Acad Sci U S A. 2004;101:14788-14793.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14788-14793
-
-
Suzuki, E.1
Handa, K.2
Toledo, M.S.3
Hakomori, S.4
-
56
-
-
4644229867
-
Sphingosine contributes to glucocorticoid-induced apoptosis of thymocytes independently of the mitochondrial pathway
-
Lépine S, Lakatos B, Courageot MP, Stunff LE, Sulpice JC, Giraud E. Sphingosine contributes to glucocorticoid-induced apoptosis of thymocytes independently of the mitochondrial pathway. J Immunol. 2004;173:3783-3790.
-
(2004)
J Immunol
, vol.173
, pp. 3783-3790
-
-
Lépine, S.1
Lakatos, B.2
Courageot, M.P.3
Stunff, L.E.4
Sulpice, J.C.5
Giraud, E.6
-
57
-
-
0026317132
-
Inhibition of sphingolipid biosynthesis by fumonisins: Implications for diseases associated with Fusarium moniliforme
-
Wang E, Norred WP, Bacon CW, Riley RT, Merrill AH Jr. Inhibition of sphingolipid biosynthesis by fumonisins: implications for diseases associated with Fusarium moniliforme. J Biol Chem. 1991;266:14486-14490.
-
(1991)
J Biol Chem
, vol.266
, pp. 14486-14490
-
-
Wang, E.1
Norred, W.P.2
Bacon, C.W.3
Riley, R.T.4
Merrill Jr., A.H.5
-
58
-
-
0027074149
-
Biosynthesis of sphingolipids: Dihydroceramide and not sphinganine is desaturated by cultured cells
-
Rother J, van Echten G, Schwarzmann G, Sandhoff K. Biosynthesis of sphingolipids: dihydroceramide and not sphinganine is desaturated by cultured cells. Biochem Biophys Res Commun. 1992;189:14-20.
-
(1992)
Biochem Biophys Res Commun
, vol.189
, pp. 14-20
-
-
Rother, J.1
van Echten, G.2
Schwarzmann, G.3
Sandhoff, K.4
-
59
-
-
0034629140
-
Cloning of an alkaline ceramidase from Saccharomyces cerevisiae: An enzyme with reverse (CoA-independent) ceramide synthase activity
-
Mao C, Xu R, Bielawska A, Obeid LM. Cloning of an alkaline ceramidase from Saccharomyces cerevisiae: an enzyme with reverse (CoA-independent) ceramide synthase activity. J Biol Chem. 2000;275:6876-6884.
-
(2000)
J Biol Chem
, vol.275
, pp. 6876-6884
-
-
Mao, C.1
Xu, R.2
Bielawska, A.3
Obeid, L.M.4
-
60
-
-
33645751575
-
Drosophila melanogaster scramblases modulate synaptic transmission
-
Acharya U, Edwards MB, Jorquera RA, et al. Drosophila melanogaster scramblases modulate synaptic transmission. J Cell Biol. 2006;173:69-82.
-
(2006)
J Cell Biol
, vol.173
, pp. 69-82
-
-
Acharya, U.1
Edwards, M.B.2
Jorquera, R.A.3
-
61
-
-
37549061432
-
Cell-nonautonomous function of ceramidase in photoreceptor homeostasis
-
Acharya JK, Dasgupta U, Rawat SS, et al. Cell-nonautonomous function of ceramidase in photoreceptor homeostasis. Neuron. 2008;57:69-79.
-
(2008)
Neuron
, vol.57
, pp. 69-79
-
-
Acharya, J.K.1
Dasgupta, U.2
Rawat, S.S.3
-
62
-
-
0031928816
-
Metabolic fate of exogenous sphingosine in neuroblastoma neuro2A cells: Dose-dependence and biological effects
-
Riboni L, Bassi R, Caminiti A, Prinetti A, Viani P, Tettamanti G. Metabolic fate of exogenous sphingosine in neuroblastoma neuro2A cells: dose-dependence and biological effects. Ann N Y Acad Sci. 1998;845:46-56.
-
(1998)
Ann N Y Acad Sci
, vol.845
, pp. 46-56
-
-
Riboni, L.1
Bassi, R.2
Caminiti, A.3
Prinetti, A.4
Viani, P.5
Tettamanti, G.6
-
63
-
-
0034662612
-
Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells
-
Nava VE, Cuvillier O, Edsall LC, et al. Sphingosine enhances apoptosis of radiation-resistant prostate cancer cells. Cancer Res. 2000;60:4468-4474.
-
(2000)
Cancer Res
, vol.60
, pp. 4468-4474
-
-
Nava, V.E.1
Cuvillier, O.2
Edsall, L.C.3
-
64
-
-
50049090026
-
Ceramidases: Regulators of cellular responses mediated by ceramide, sphingosine and sphingosine-1-phosphate
-
Mao C, Obeid LM. Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine and sphingosine-1-phosphate. Biochim Biophys Acta. 2008;1781:424-434.
-
(2008)
Biochim Biophys Acta
, vol.1781
, pp. 424-434
-
-
Mao, C.1
Obeid, L.M.2
-
65
-
-
1842330849
-
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species: Role of mitochondrial glutathione
-
García-Ruiz C, Colell A, Mar M, Morales A, Fernandez-Checai JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species: role of mitochondrial glutathione. J Biol Chem. 1997;272:11369-11377.
-
(1997)
J Biol Chem
, vol.272
, pp. 11369-11377
-
-
García-Ruiz, C.1
Colell, A.2
Mar, M.3
Morales, A.4
Fernandez-Checai, J.C.5
-
66
-
-
56949105142
-
Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system
-
Okada T, Kajimoto T, Jahangeer S, Nakamura S-i. Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system. Cellular Sign. 2009;21:7-13.
-
(2009)
Cellular Sign
, vol.21
, pp. 7-13
-
-
Okada, T.1
Kajimoto, T.2
Jahangeer, S.3
Nakamura, S.-I.4
-
67
-
-
50949088162
-
Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling
-
Lebman DA, Spiegel S. Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling. J Lipid Res. 2008;49:1388-1394.
-
(2008)
J Lipid Res
, vol.49
, pp. 1388-1394
-
-
Lebman, D.A.1
Spiegel, S.2
-
68
-
-
70349238786
-
Sphingosine-1-phosphate is a key regulator of photoreceptors and differentiation in retina photoreceptors
-
Miranda GE, Abrahan CE, Politi LE, Rotstein NP. Sphingosine-1-phosphate is a key regulator of photoreceptors and differentiation in retina photoreceptors. Invest Ophthalmol Vis Sci. 2009;50(9):4416-4428.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, Issue.9
, pp. 4416-4428
-
-
Miranda, G.E.1
Abrahan, C.E.2
Politi, L.E.3
Rotstein, N.P.4
-
69
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
Spiegel S, Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol. 2003;4:397-407.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
|