메뉴 건너뛰기




Volumn 59, Issue 4, 2010, Pages 599-607

Homeostasis of peripheral FoxP3+ CD4+ regulatory T cells in patients with early and late stage breast cancer

Author keywords

Breast cancer; Clinical trial; Regulatory T cell

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DOXORUBICIN; GAMMA INTERFERON; TAXANE DERIVATIVE; TRANSCRIPTION FACTOR FOXP3; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN;

EID: 77449101222     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-009-0780-x     Document Type: Article
Times cited : (39)

References (44)
  • 2
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: multiple varieties of t regulatory cells
    • DOI 10.1016/j.immuni.2006.08.003, PII S1074761306003578
    • Shevach EM (2006) From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 25:195-201 (Pubitemid 44224153)
    • (2006) Immunity , vol.25 , Issue.2 , pp. 195-201
    • Shevach, E.M.1
  • 3
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W (2006) Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 6:295-307
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 4
    • 43949105866 scopus 로고    scopus 로고
    • Regulatory T cells and immune tolerance
    • Sakaguchi S, Yamaguchi T, Nomura T, Ono M (2008) Regulatory T cells and immune tolerance. Cell 133:775-787
    • (2008) Cell , vol.133 , pp. 775-787
    • Sakaguchi, S.1    Yamaguchi, T.2    Nomura, T.3    Ono, M.4
  • 5
    • 0348013075 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory cells have marked and sustained effects on CD8+ T cell activation
    • Camara NO, Sebille F, Lechler RI (2003) Human CD4+ CD25+ regulatory cells have marked and sustained effects on CD8+ T cell activation. Eur J Immunol 33:3473-3483
    • (2003) Eur J Immunol , vol.33 , pp. 3473-3483
    • Camara, N.O.1    Sebille, F.2    Lechler, R.I.3
  • 6
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+ CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton AM, Shevach EM (2000) Suppressor effector function of CD4+ CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 164:183-190
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 10
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, Alvarez X, Cheng P et al (2004) Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 10:942-949
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3    Alvarez, X.4    Cheng, P.5
  • 11
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+ CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F (2003) An essential role for Scurfin in CD4+ CD25+ T regulatory cells. Nat Immunol 4:337-342
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 13
    • 33646240855 scopus 로고    scopus 로고
    • Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
    • USA
    • Gavin MA, Torgerson TR, Houston E, DeRoos P, Ho WY et al (2006) Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci USA 103:6659-6664
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 6659-6664
    • Gavin, M.A.1    Torgerson, T.R.2    Houston, E.3    Deroos, P.4    Ho, W.Y.5
  • 14
    • 34247172466 scopus 로고    scopus 로고
    • IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells
    • DOI 10.1097/CJI.0b013e3180336787, PII 0000237120070400000005
    • Ahmadzadeh M, Antony PA, Rosenberg SA (2007) IL-2 and IL15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother 30:294-302 (Pubitemid 46586645)
    • (2007) Journal of Immunotherapy , vol.30 , Issue.3 , pp. 294-302
    • Ahmadzadeh, M.1    Antony, P.A.2    Rosenberg, S.A.3
  • 16
    • 0022517682 scopus 로고
    • + suppressors of delayed sensitivity precedes the production of suppressors of protective immunity
    • DiGiacomoA,NorthRJ(1986)Tcellsuppressorsofantitumorimmunity: theproductionofLy-1-, 2+suppressorsofdelayedsensitivityprecedestheproductionofsuppressorsofprotect iveimmunity.JExpMed164:1179-1192(Pubitemid16031615)
    • (1986) Journal of Experimental Medicine , vol.164 , Issue.4 , pp. 1179-1192
    • Digiacomo, A.1    North, R.J.2
  • 17
    • 4644342928 scopus 로고    scopus 로고
    • Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
    • Turk MJ, Guevara-Patino JA, Rizzuto GA, Engelhorn ME, Sakaguchi S et al (2004) Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J Exp Med 200:771-782
    • (2004) J Exp Med , vol.200 , pp. 771-782
    • Turk, M.J.1    Guevara-Patino, J.A.2    Rizzuto, G.A.3    Engelhorn, M.E.4    Sakaguchi, S.5
  • 18
    • 21144454780 scopus 로고    scopus 로고
    • Recruitment of latent pools of highavidity CD8(+) T cells to the antitumor immune response
    • Ercolini AM, Ladle BH, Manning EA, Pfannenstiel LW, Armstrong TD et al (2005) Recruitment of latent pools of highavidity CD8(+) T cells to the antitumor immune response. J Exp Med 201:1591-1602
    • (2005) J Exp Med , vol.201 , pp. 1591-1602
    • Ercolini, A.M.1    Ladle, B.H.2    Manning, E.A.3    Pfannenstiel, L.W.4    Armstrong, T.D.5
  • 19
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor α) monoclonal antibody
    • OnizukaS,TawaraI,ShimizuJ,SakaguchiS,FujitaTetal(1999) Tumorrejectionbyinvivoadministrationofanti-CD25(interleukin2receptoralpha) monoclonalantibody.CancerRes59:3128-3133(Pubitemid29316012)
    • (1999) Cancer Research , vol.59 , Issue.13 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 20
    • 0033571105 scopus 로고    scopus 로고
    • Induction of tumor immunity by removing CD25+ CD4+ T cells: A common basis between tumor immunity and autoimmunity
    • Shimizu J, Yamazaki S, Sakaguchi S (1999) Induction of tumor immunity by removing CD25+ CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol 163:5211-5218
    • (1999) J Immunol , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 21
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller RP, van Duivenvoorde LM, van Elsas A, Schumacher TN, Wildenberg ME et al (2001) Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 194:823-832
    • (2001) J Exp Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    Van Duivenvoorde, L.M.2    Van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5
  • 23
    • 27444435581 scopus 로고    scopus 로고
    • 389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • AttiaP,MakerAV,HaworthLR,Rogers-FreezerL,RosenbergSA(2005) InabilityofafusionproteinofIL-2anddiphtheriatoxin(DenileukinDiftitox,DAB389IL-2, ONTAK)-eliminateregulatoryTlymphocytesinpatientswithmelanoma.JImmunother28: 582-592(Pubitemid41533092)
    • (2005) Journal of Immunotherapy , vol.28 , Issue.6 , pp. 582-592
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3    Rogers-Freezer, L.4    Rosenberg, S.A.5
  • 26
    • 44949111435 scopus 로고    scopus 로고
    • Partial reduction of human FoxP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration
    • Powell DJ Jr, Attia P, Ghetie V, Schindler J, Vitetta ES et al (2008) Partial reduction of human FoxP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration. J Immunother 31:189-198
    • (2008) J Immunother , vol.31 , pp. 189-198
    • Powell Jr., D.J.1    Attia, P.2    Ghetie, V.3    Schindler, J.4    Vitetta, E.S.5
  • 28
    • 50949115267 scopus 로고    scopus 로고
    • Depletion of human regulatory T cells specifically enhances antigen specific immune responses to cancer vaccines
    • Morse MA, Hobeika AC, Osada T, Serra D, Niedzwiecki D et al (2008) Depletion of human regulatory T cells specifically enhances antigen specific immune responses to cancer vaccines. Blood 112:610-618
    • (2008) Blood , vol.112 , pp. 610-618
    • Morse, M.A.1    Hobeika, A.C.2    Osada, T.3    Serra, D.4    Niedzwiecki, D.5
  • 29
    • 34247261531 scopus 로고    scopus 로고
    • Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
    • DOI 10.1200/JCO.2006.05.9584
    • Bates GJ, Fox SB, Han C, Leek RD, Garcia JF et al (2006) Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse. J Clin Oncol 24:5373-5380 (Pubitemid 46623168)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.34 , pp. 5373-5380
    • Bates, G.J.1    Fox, S.B.2    Han, C.3    Leek, R.D.4    Garcia, J.F.5    Harris, A.L.6    Banham, A.H.7
  • 31
    • 0037687355 scopus 로고    scopus 로고
    • Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: First report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741
    • Citron ML, Berry DA, Cirrincione C, Hudis C, Winer EP et al (2003) Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J Clin Oncol 21:1431-1439
    • (2003) J Clin Oncol , vol.21 , pp. 1431-1439
    • Citron, M.L.1    Berry, D.A.2    Cirrincione, C.3    Hudis, C.4    Winer, E.P.5
  • 32
    • 34247270770 scopus 로고    scopus 로고
    • Phase III trial comparing doxorubicin plus cyclophosphamide with docetaxel plus cyclophosphamide as adjuvant therapy for operable breast cancer
    • Jones SE, Savin MA, Holmes FA, O'Shaughnessy JA, Blum. JL et al (2006) Phase III trial comparing doxorubicin plus cyclophosphamide with docetaxel plus cyclophosphamide as adjuvant therapy for operable breast cancer. J Clin Oncol 24:5381-5387
    • (2006) J Clin Oncol , vol.24 , pp. 5381-5387
    • Jones, S.E.1    Savin, M.A.2    Holmes, F.A.3    O'Shaughnessy, J.A.4    Blum, J.L.5
  • 33
    • 53149092106 scopus 로고    scopus 로고
    • CD28 costimulation is essential for human T regulatory expansion and function
    • Golovina TN, Mikheeva T, Suhoski MM, Aqui NA, Tai VC et al (2008) CD28 costimulation is essential for human T regulatory expansion and function. J Immunol 181:2855-2868
    • (2008) J Immunol , vol.181 , pp. 2855-2868
    • Golovina, T.N.1    Mikheeva, T.2    Suhoski, M.M.3    Aqui, N.A.4    Tai, V.C.5
  • 34
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B 57:289-300
    • (1995) J R Statist Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 35
    • 38049110724 scopus 로고    scopus 로고
    • Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259.D as the outlier with lower sensitivity
    • Pillai V, Karandikar NJ (2008) Attack on the clones? Human FOXP3 detection by PCH101, 236A/E7, 206D, and 259D reveals 259.D as the outlier with lower sensitivity. Blood 111:463-464
    • (2008) Blood , vol.111 , pp. 463-464
    • Pillai, V.1    Karandikar, N.J.2
  • 36
    • 35448930435 scopus 로고    scopus 로고
    • - T cells by T-cell receptor stimulation is transforming growth factor-β-dependent but does not confer a regulatory phenotype
    • DOI 10.1182/blood-2007-06-094656
    • Tran DQ, Ramsey H, Shevach EM (2007) Induction of FOXP3 expression in naive human CD4+ FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood 110:2983-2990 (Pubitemid 350006952)
    • (2007) Blood , vol.110 , Issue.8 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 37
    • 49649113444 scopus 로고    scopus 로고
    • Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3
    • Zheng Y, Manzotti CN, Burke F, Dussably L, Qureshi O et al (2008) Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3. J Immunol 181:1683-1691
    • (2008) J Immunol , vol.181 , pp. 1683-1691
    • Zheng, Y.1    Manzotti, C.N.2    Burke, F.3    Dussably, L.4    Qureshi, O.5
  • 38
    • 58149399352 scopus 로고    scopus 로고
    • FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions
    • Ahmadzadeh M, Felipe-Silva A, Heemskerk B, Powell DJ Jr, Wunderlich JR et al (2008) FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions. Blood 112:49534960
    • (2008) Blood , vol.112 , pp. 49534960
    • Ahmadzadeh, M.1    Felipe-Silva, A.2    Heemskerk, B.3    Jr, P.D.J.4    Wunderlich, J.R.5
  • 39
    • 65949111746 scopus 로고    scopus 로고
    • FOXP3 defines regulatory T cells in human tumor and autoimmune disease
    • Kryczek I, Liu R, Wang G, Wu K, Shu X et al (2009) FOXP3 defines regulatory T cells in human tumor and autoimmune disease. Cancer Res 69:3995-4000
    • (2009) Cancer Res , vol.69 , pp. 3995-4000
    • Kryczek, I.1    Liu, R.2    Wang, G.3    Wu, K.4    Shu, X.5
  • 41
    • 33646182056 scopus 로고    scopus 로고
    • Are regulatory T-cells linked with aging?
    • Dejaco C, Duftner C, Schirmer M (2006) Are regulatory T-cells linked with aging? Exp Gerontol 41:339-345
    • (2006) Exp Gerontol , vol.41 , pp. 339-345
    • Dejaco, C.1    Duftner, C.2    Schirmer, M.3
  • 43
    • 49649117750 scopus 로고    scopus 로고
    • Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation
    • Lages CS, Suffia I, Velilla PA, Huang B, Warshaw G et al (2008) Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J Immunol 181:1835-1848
    • (2008) J Immunol , vol.181 , pp. 1835-1848
    • Lages, C.S.1    Suffia, I.2    Velilla, P.A.3    Huang, B.4    Warshaw, G.5
  • 44
    • 70350496784 scopus 로고    scopus 로고
    • Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells
    • Rech AJ, Vonderheide RH (2009) Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells. Ann N Y Acad Sci 1174:99-106
    • (2009) Ann N y Acad Sci , vol.1174 , pp. 99-106
    • Rech, A.J.1    Vonderheide, R.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.