Polyglutamine-expanded ataxin-7 causes cerebellar dysfunction by inducing transcriptional dysregulation

Neurochemistry International

Volumn 56, Issue 2, 2010, Pages 329-339

  Chou, An Hsun ^a   Chen, Chia Yang ^b   Chen, Si Ying ^b   Chen, Wei June ^b   Chen, Ying Ling ^b,c   Weng, Yi Shin ^a   Wang, Hung Li ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Ataxin 7; Cerebellum; Polyglutamine expanded ataxin 7; SCA7 transgenic mice; Spinocerebellar ataxia type 7

Indexed keywords

ATAXIN 7; MESSENGER RNA; POLYGLUTAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA; CEREBELLUM DISEASE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; MICROARRAY ANALYSIS; MOTOR DYSFUNCTION; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK FACTOR; SPINOCEREBELLAR DEGENERATION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINOCEREBELLAR ATAXIAS; TRANSCRIPTION, GENETIC;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 77149137999     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.11.003     Document Type: Article

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