Polyglutamine domain modulates the TBP-TFIIB interaction: Implications for its normal function and neurodegeneration

Nature Neuroscience

Volumn 10, Issue 12, 2007, Pages 1519-1528

  Friedman, Meyer J ^a   Shah, Anjali G ^a   Fang, Zhi Hui ^a   Ward, Elizabeth G ^a   Warren, Stephen T ^a   Li, Shihua ^a   Li, Xiao Jiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 1; POLYGLUTAMINE; SPINOCEREBELLAR ATAXIA 17 PROTEIN; TATA BINDING PROTEIN ASSOCIATED FACTOR; TRANSCRIPTION FACTOR IIB; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; GENE OVEREXPRESSION; MOUSE; NERVE DEGENERATION; NEURITIS; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SPINOCEREBELLAR DEGENERATION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; WEIGHT REDUCTION;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; NEOPLASM PROTEINS; NEURODEGENERATIVE DISEASES; NEURONS; POLYGLUTAMIC ACID; RATS; TATA-BOX BINDING PROTEIN; TRANSCRIPTION FACTOR TFIIB; TRANSFECTION;

EID: 36448930958     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn2011     Document Type: Article

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