Relation between statistics and treatment-related changes obtained from toxicity studies in rats: If detected a significant difference in low or middle dose for quantitative values, this change is considered as incidental change?

Journal of Toxicological Sciences

Volumn 35, Issue 1, 2010, Pages 79-85

  Kobayashi, Katsumi ^a   Sakuratani, Yuki ^a   Abe, Takemaru ^a   Nishikawa, Satoshi ^a   Yamada, Jun ^a   Hirose, Akihiko ^b   Kamata, Eiichi ^b   Hayashi, Makoto ^a,c  

^a NATIONAL INSTITUTE OF TECHNOLOGY AND EVALUATION   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c Biosafety Research Center   (Japan)

Author keywords

Historical control data; Incidental change; Rodents; Standard deviation and error; Statistics; Toxicity

Indexed keywords

CHEMICAL COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; INTERMETHOD COMPARISON; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; RELIABILITY; STATISTICS; TOXICITY TESTING;

RATTUS; RODENTIA;

EID: 76749156276     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.35.79     Document Type: Article

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