Tree-type algorithm for statistical analysis in chronic toxicity studies

Journal of Toxicological Sciences

Volumn 23, Issue 3, 1998, Pages 173-181

  Hamada, Chikuma ^a   Yoshino, Kei ^b   Matsumoto, Kazuhiko ^b   Nomura, Mamoru ^c   Yoshimura, Isao ^d  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN TOBACCO INC   (Japan)

^c DAIICHI SANKYO CO   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Decision tree; Statistical analysis and Repeated toxicity studies; Tree type algorithm

Indexed keywords

ALGORITHM; CHRONIC TOXICITY; DATA ANALYSIS; HUMAN; JAPAN; REVIEW; STATISTICAL ANALYSIS;

RODENTIA;

EID: 0031694156     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.23.3_173     Document Type: Review

References (15)

1. Box, G.E.P.(1954): Some theorems on quadratic forms applied in the study of analysis of variance problems. I. Effect of inequality of variance in the one-way classification. Ann. Math. Stat., 290-302
2. Draper, N.R. and Smith, H.(1968): Applied Regression Analysis. John Wiley and Sons, New York.
3. Dunnett, C.W.(1975): A multiple comparison procedure for comparing several treatments with a control. JASA, 50, 1096-1121
4. Hamada, C., Yoshino, K., Abe, I., Matsumoto, K., Nomura,M. and Yoshimura, I.(1997):A study on the consistency between statistical evaluation and toxicological judgment. Drug Inf. J., 31-2, 413-421.
5. Hamada, C., Yoshino, K., Abe, I., Matsumoto, K., Nomura, M.and Yoshimura, I.(1998): Detection of an outlier and evaluation of its influence in chronic toxicity studies. Drug Inf. J., 32-1, 101-112.
6. Healey, G.F. (1997): How to achieve standardization of statistical methods in toxicology.Drug Inf. J., 31-2, 395-401.
7. Hothorn, L.A. , Lin, K., Hamada, C. and Rebel, W.(1997): Recommendation for biostatistics of repeated toxicity studies. Drug Inf. J., 31-2, 327-334.
8. Kobayashi, K., Watanabe, K. and Inoue, H.(1995): Questioning the usefulness of the non-parametric analysis of quantitative data into ranked data in toxicology studies. J. Toxicol. Sci., 20, 47-53
9. Levene, H.(1960): Robust tests for the equality of variance. In Contributions to Probability and Statistics, (Olkin, I., ed.) 278-292, Stanford University Press, Stanford.
10. SAS Institute Inc.(1992): SAS/STAT User's Guide Version 6 Fourth Edition. SAS Institute Inc.,Cary, NC.
11. SAS Institute Inc.(1993): SAS/INSIGHT® User's Guide Version 6 Second Edition, SAS Institute Inc., Cary, NC.
12. Yamazaki, M., Noguchi, Y., Tanda, M. and Shintani, S.(1981): Statistical methods appropriate for general toxicological studies in rats. Algorithms for multiple comparisons of treatment groups with control. J. Takeda Res. Lab., 40, 163-187 (in Japanese).
13. Uesaka, H.(1995): Handbook of statistics in medicine, (ed. Tango, T. and Miyahara, H.) Asakura Publishing Corp.,Tokyo, 58-63 (in Japanese).
14. Weisberg, S.(1985): Applied Linear Regression, Second Edition. John Wiley and Sons, New York.
15. Williams, D.A.(1971): A test for differences between treatment means when several dose levels are compared with a zero dose control. Biometrics, 27, 103-117.