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Volumn 36, Issue 5, 1998, Pages 429-436

2-ethylhexanoic acid: Subchronic oral toxicity studies in the rat and mouse

Author keywords

[No Author keywords available]

Indexed keywords

HEXANOIC ACID DERIVATIVE; PLASTICIZER;

EID: 0031835129     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(97)00168-3     Document Type: Article
Times cited : (16)

References (27)
  • 1
    • 0016703454 scopus 로고
    • The metabolism of 2-ethylhexanol in rats
    • Albro P. W. The metabolism of 2-ethylhexanol in rats. Xenobiotica. 5:1975;25-636.
    • (1975) Xenobiotica , vol.5 , pp. 25-636
    • Albro, P.W.1
  • 4
    • 0017873422 scopus 로고
    • Studies on lipid biosynthesis and cholesterol content of liver and serum lipoproteins in rats fed various phthalate esters
    • Bell F. P., Patt C. S., Brundage B., Gillies P. J., Phillips W. A. Studies on lipid biosynthesis and cholesterol content of liver and serum lipoproteins in rats fed various phthalate esters. Lipids. 13:1977;66-74.
    • (1977) Lipids , vol.13 , pp. 66-74
    • Bell, F.P.1    Patt, C.S.2    Brundage, B.3    Gillies, P.J.4    Phillips, W.A.5
  • 5
    • 0019824670 scopus 로고
    • Review of the hepatic response to hypolipidaemic drugs in rodents and assessment of its toxicological significance to man
    • Cohen A. J., Grasso P. Review of the hepatic response to hypolipidaemic drugs in rodents and assessment of its toxicological significance to man. Food and Cosmetics Toxicology. 19:1981;585-605.
    • (1981) Food and Cosmetics Toxicology , vol.19 , pp. 585-605
    • Cohen, A.J.1    Grasso, P.2
  • 8
    • 0025139836 scopus 로고
    • Asymmetric synthesis and teratogenic activity of (R)- and (S)-2-ethylhexanoic acid, a metabolite of the plasticizer di(2-ethylhexyl)phthalate
    • Hauck R. S., Wegner C., Blumtritt P., Fuhrhop J. H., Nau H. Asymmetric synthesis and teratogenic activity of (R)- and (S)-2-ethylhexanoic acid, a metabolite of the plasticizer di(2-ethylhexyl)phthalate. Life Sciences. 46:1990;513-518.
    • (1990) Life Sciences , vol.46 , pp. 513-518
    • Hauck, R.S.1    Wegner, C.2    Blumtritt, P.3    Fuhrhop, J.H.4    Nau, H.5
  • 10
    • 0022560393 scopus 로고
    • Carcinogenic potential of phthalic acid esters and related compound: Structure-activity relationships
    • Kluwe W. M. Carcinogenic potential of phthalic acid esters and related compound: structure-activity relationships. Environmental Health Perspectives. 65:1986;271-278.
    • (1986) Environmental Health Perspectives , vol.65 , pp. 271-278
    • Kluwe, W.M.1
  • 11
    • 0342693841 scopus 로고
    • Effects of di-2-ethyl hexyl phthalate and four metabolites on rodent hepatocyte gap junctional intercellular communication
    • Lington A. W., Kalimi G. H., Nikiforov A. I., Klaunig J. E. Effects of di-2-ethyl hexyl phthalate and four metabolites on rodent hepatocyte gap junctional intercellular communication. Toxicologist. 14:1994;57a.
    • (1994) Toxicologist , vol.14
    • Lington, A.W.1    Kalimi, G.H.2    Nikiforov, A.I.3    Klaunig, J.E.4
  • 12
    • 0024217587 scopus 로고
    • Induction of cytosolic and microsomal epoxide hydrolases in mouse liver by peroxisome proliferators, with special emphasis on structural analogues of 2-ethylhexanoic acid
    • Lundgren B., Meijer J., Birberg W., Pilotti A., DePierre J. W. Induction of cytosolic and microsomal epoxide hydrolases in mouse liver by peroxisome proliferators, with special emphasis on structural analogues of 2-ethylhexanoic acid. Chemico-Biological Interactions. 68:1988;219-240.
    • (1988) Chemico-Biological Interactions , vol.68 , pp. 219-240
    • Lundgren, B.1    Meijer, J.2    Birberg, W.3    Pilotti, A.4    DePierre, J.W.5
  • 13
    • 0024582579 scopus 로고
    • 2-ethylhexanoic acid inhibits urea synthesis and stimulates carnitine acetyltransferase activity in rat liver mitochondria
    • Manninen A., Kröger S., Liesivuori J., Savolainen H. 2-Ethylhexanoic acid inhibits urea synthesis and stimulates carnitine acetyltransferase activity in rat liver mitochondria. Archives of Toxicology. 63:1989;160-161.
    • (1989) Archives of Toxicology , vol.63 , pp. 160-161
    • Manninen, A.1    Kröger, S.2    Liesivuori, J.3    Savolainen, H.4
  • 15
    • 0023802938 scopus 로고
    • Forestomach lesions induced by butylated hydroxyanisole and ethylene dibromide: A scientific and regulatory perspective
    • Moch R. W. Forestomach lesions induced by butylated hydroxyanisole and ethylene dibromide: a scientific and regulatory perspective. Toxicologic Pathology. 16:1988;172-183.
    • (1988) Toxicologic Pathology , vol.16 , pp. 172-183
    • Moch, R.W.1
  • 16
    • 0018172473 scopus 로고
    • Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds
    • Moody D. E., Reddy J. K. Hepatic peroxisome (microbody) proliferation in rats fed plasticizers and related compounds. Toxicology and Applied Pharmacology. 45:1978;497-504.
    • (1978) Toxicology and Applied Pharmacology , vol.45 , pp. 497-504
    • Moody, D.E.1    Reddy, J.K.2
  • 17
    • 0020066337 scopus 로고
    • Serum triglycerides and cholesterol contents in male rats receiving diets containing plasticizers and analogues of the ester 2-ethylhexanol
    • Moody D. E., Reddy J. K. Serum triglycerides and cholesterol contents in male rats receiving diets containing plasticizers and analogues of the ester 2-ethylhexanol. Toxicology Letters. 10:1982;379-383.
    • (1982) Toxicology Letters , vol.10 , pp. 379-383
    • Moody, D.E.1    Reddy, J.K.2
  • 18
    • 0007328602 scopus 로고
    • Technical Report No. 212, National Toxicology Program, Research Triangle Park, NC
    • 1 Mice. Technical Report No. 212, National Toxicology Program, Research Triangle Park, NC.
    • (1982) 1 Mice
  • 19
    • 0007328602 scopus 로고
    • Technical Report No. 217, National Toxicology Program, Research Triangle Park, NC
    • 1 Mice (Feed Study). Technical Report No. 217, National Toxicology Program, Research Triangle Park, NC.
    • (1982) 1 Mice (Feed Study)
  • 20
    • 0027508981 scopus 로고
    • Strain differences in susceptibility to di-2-ethylhexyl phthalate-induced testicular atrophy in mice
    • Oishi S. Strain differences in susceptibility to di-2-ethylhexyl phthalate-induced testicular atrophy in mice. Toxicology Letters. 66:1993;47-52.
    • (1993) Toxicology Letters , vol.66 , pp. 47-52
    • Oishi, S.1
  • 24
    • 0015957351 scopus 로고
    • Influence of dietary fat and di-2-ethylhexyl phthalate on tissue lipids in rats
    • Stein M. S., Caasi P. I., Nair P. P. Influence of dietary fat and di-2-ethylhexyl phthalate on tissue lipids in rats. Journal of Nutrition. 104:1974;187-191.
    • (1974) Journal of Nutrition , vol.104 , pp. 187-191
    • Stein, M.S.1    Caasi, P.I.2    Nair, P.P.3
  • 26
    • 0344482784 scopus 로고    scopus 로고
    • Maternal exposure to 2-ethylhexanoic acid (EHXA), 2-ethylhexanol (EHXO), and valproic acid (VPA). Results in alterations in maternal and embryonic zinc status
    • Taubeneck M. W., Uriu-Hare J. Y., Commisso J. F., Borschers A. T., Bui L. M., Faber W., Keen C. L. Maternal exposure to 2-ethylhexanoic acid (EHXA), 2-ethylhexanol (EHXO), and valproic acid (VPA). Results in alterations in maternal and embryonic zinc status. Teratology. 53:1996;88a.
    • (1996) Teratology , vol.53
    • Taubeneck, M.W.1    Uriu-Hare, J.Y.2    Commisso, J.F.3    Borschers, A.T.4    Bui, L.M.5    Faber, W.6    Keen, C.L.7
  • 27
    • 0344914039 scopus 로고
    • Dynamac Corporation, 11140 Rockville Pike, Rockville, MD 20852
    • Union Carbide Corporation (1983). Letter with attachments from TR. Tyler to L. Borghi, Dynamac Corporation, 11140 Rockville Pike, Rockville, MD 20852.
    • (1983) Letter with Attachments from TR. Tyler to L. Borghi


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