Oral repeated-dose toxicity studies and toxicokinetic studies of telithromycin in rats

Japanese Journal of Chemotherapy

Volumn 51, Issue SUPPL. 1, 2003, Pages 103-114

  Omosu, Mikio ^a   Eluard, B ^b   Thien Aubert, H ^b   Stepniewski, J P ^b   Vidal, J M ^b   Bode, G ^b   Roeder, V ^a   Bonnat, C ^b   Lenfant, B ^b   Sacre Salem, B ^b   Guffroy, M ^b   Detilleux, P G ^b  

^a Aventis Pharma Ltd   (Japan)

^b SANOFI   (France)

Author keywords

Rats; Repeated dose toxicity study; Telithromycin; Toxicokinetic study

Indexed keywords

LIVER ENZYME; TELITHROMYCIN;

ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; AUTOPSY; BILE DUCT DISEASE; CECUM; CELL DEATH; CELL INFILTRATION; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG TOXICITY; HISTOPATHOLOGY; ILEUM DISEASE; INCIDENCE; INTESTINE FLORA; JEJUNUM DISEASE; LIPIDOSIS; LIVER CELL; LIVER DYSFUNCTION; LIVER HYPERTROPHY; LIVER NECROSIS; LIVER WEIGHT; LUNG DISEASE; MESENTERY LYMPH NODE; MONONUCLEAR CELL; MULTINUCLEAR CELL; MULTIPLE DRUG DOSE; NONHUMAN; ORGAN SIZE; RAT; SEX RATIO; SPLEEN DISEASE; TOXICOKINETICS; WEIGHT REDUCTION;

EID: 0142210349     PISSN: 13407007     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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