메뉴 건너뛰기




Volumn 26, Issue 1, 2010, Pages 77-84

Roles of the prostaglandin E2 receptors EP subtypes in Alzheimer's disease

Author keywords

Alzheimer's disease; Inflammation; Prostaglandin E2; Prostaglandin E2 receptors

Indexed keywords

AMYLOID BETA PROTEIN; CYCLOOXYGENASE 2; MISOPROSTOL; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN E2 RECEPTOR EP1; PROSTAGLANDIN E2 RECEPTOR EP2; PROSTAGLANDIN E2 RECEPTOR EP3; PROSTAGLANDIN E2 RECEPTOR EP4; UNCLASSIFIED DRUG;

EID: 76649098525     PISSN: 16737067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12264-010-0703-z     Document Type: Short Survey
Times cited : (12)

References (46)
  • 1
    • 53949088425 scopus 로고    scopus 로고
    • Genetic predisposition to inflammation: A new risk factor of Alzheimer's disease
    • 10.1007/s12264-008-0619-z 1:CAS:528:DC%2BD1MXhtVyrsLrO 18839025
    • Y. Wan G. Wang S.D. Chen 2008 Genetic predisposition to inflammation: a new risk factor of Alzheimer's disease Neurosci Bull 24 314 322 10.1007/s12264-008-0619-z 1:CAS:528:DC%2BD1MXhtVyrsLrO 18839025
    • (2008) Neurosci Bull , vol.24 , pp. 314-322
    • Wan, Y.1    Wang, G.2    Chen, S.D.3
  • 3
    • 0038375640 scopus 로고    scopus 로고
    • Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: Systematic review and meta-analysis of observational studies
    • 10.1136/bmj.327.7407.128 1:CAS:528:DC%2BD3sXmsl2nu7o%3D 12869452
    • M. Etminan S. Gill A. Samii 2003 Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies BMJ 327 128 10.1136/bmj.327.7407.128 1:CAS:528:DC%2BD3sXmsl2nu7o%3D 12869452
    • (2003) BMJ , vol.327 , pp. 128
    • Etminan, M.1    Gill, S.2    Samii, A.3
  • 5
    • 3242803587 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: A systematic review
    • DOI 10.1159/000078501
    • C.A. Szekely J.E. Thorne P.P. Zandi M. Ek E. Messias J.C. Breitner, et al. 2004 Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review Neuroepidemiology 23 159 169 10.1159/000078501 15279021 (Pubitemid 38980441)
    • (2004) Neuroepidemiology , vol.23 , Issue.4 , pp. 159-169
    • Szekely, C.A.1    Thorne, J.E.2    Zandi, P.P.3    Ek, M.4    Messias, E.5    Breitner, J.C.S.6    Goodman, S.N.7
  • 6
    • 0037088914 scopus 로고    scopus 로고
    • Microglial activation and beta-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice
    • 1:CAS:528:DC%2BD38XisVGisbo%3D 11896164
    • P.T. Jantzen K.E. Connor G. DiCarlo G.L. Wenk J.L. Wallace A.M. Rojiani, et al. 2002 Microglial activation and beta-amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice J Neurosci 22 2246 2254 1:CAS:528:DC%2BD38XisVGisbo%3D 11896164
    • (2002) J Neurosci , vol.22 , pp. 2246-2254
    • Jantzen, P.T.1    Connor, K.E.2    Dicarlo, G.3    Wenk, G.L.4    Wallace, J.L.5    Rojiani, A.M.6
  • 7
    • 0034254924 scopus 로고    scopus 로고
    • Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease
    • 1:CAS:528:DC%2BD3cXlt1Gltbk%3D 10908610
    • G.P. Lim F. Yang T. Chu P. Chen W. Beech B. Teter, et al. 2000 Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease J Neurosci 20 5709 5714 1:CAS:528:DC%2BD3cXlt1Gltbk%3D 10908610
    • (2000) J Neurosci , vol.20 , pp. 5709-5714
    • Lim, G.P.1    Yang, F.2    Chu, T.3    Chen, P.4    Beech, W.5    Teter, B.6
  • 8
    • 0041921071 scopus 로고    scopus 로고
    • Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease
    • 1:CAS:528:DC%2BD3sXmvFaisLg%3D 12930788
    • Q. Yan J. Zhang H. Liu S. Babu-Khan R. Vassar A.L. Biere, et al. 2003 Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease J Neurosci 23 7504 7509 1:CAS:528:DC%2BD3sXmvFaisLg%3D 12930788
    • (2003) J Neurosci , vol.23 , pp. 7504-7509
    • Yan, Q.1    Zhang, J.2    Liu, H.3    Babu-Khan, S.4    Vassar, R.5    Biere, A.L.6
  • 9
    • 46049108790 scopus 로고    scopus 로고
    • No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies
    • 10.1212/01.wnl.0000313933.17796.f6 1:CAS:528:DC%2BD1cXmsFylsrg%3D 18509093
    • C.A. Szekely R.C. Green J.C. Breitner T. Ostbye A.S. Beiser M.M. Corrada, et al. 2008 No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies Neurology 70 2291 2298 10.1212/01.wnl.0000313933.17796.f6 1:CAS:528:DC%2BD1cXmsFylsrg%3D 18509093
    • (2008) Neurology , vol.70 , pp. 2291-2298
    • Szekely, C.A.1    Green, R.C.2    Breitner, J.C.3    Ostbye, T.4    Beiser, A.S.5    Corrada, M.M.6
  • 10
    • 44949084672 scopus 로고    scopus 로고
    • Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology
    • 10.1212/01.wnl.0000313813.48505.86 1:STN:280:DC%2BD1czmtVOjtQ%3D%3D 18519870
    • Z. Arvanitakis F. Grodstein J.L. Bienias J.A. Schneider R.S. Wilson J.F. Kelly, et al. 2008 Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology Neurology 70 2219 2225 10.1212/01.wnl.0000313813. 48505.86 1:STN:280:DC%2BD1czmtVOjtQ%3D%3D 18519870
    • (2008) Neurology , vol.70 , pp. 2219-2225
    • Arvanitakis, Z.1    Grodstein, F.2    Bienias, J.L.3    Schneider, J.A.4    Wilson, R.S.5    Kelly, J.F.6
  • 11
    • 26944469609 scopus 로고    scopus 로고
    • Anti-inflammatory mechanism of non-steroidal anti-inflammatory drugs
    • 1:CAS:528:DC%2BD28XpvFKqtLk%3D
    • B. Zhang G.H. Du 2005 Anti-inflammatory mechanism of non-steroidal anti-inflammatory drugs Chin Pharm Bull 21 905 910 1:CAS:528: DC%2BD28XpvFKqtLk%3D
    • (2005) Chin Pharm Bull , vol.21 , pp. 905-910
    • Zhang, B.1    Du, G.H.2
  • 12
    • 0042904882 scopus 로고    scopus 로고
    • Aβ42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain
    • DOI 10.1074/jbc.M304824200
    • S. Weggen J.L. Eriksen S.A. Sagi C.U. Pietrzik T.E. Golde E.H. Koo 2003 Abeta42-lowering nonsteroidal anti-inflammatory drugs preserve intramembrane cleavage of the amyloid precursor protein (APP) and ErbB-4 receptor and signaling through the APP intracellular domain J Biol Chem 278 30748 30754 10.1074/jbc.M304824200 1:CAS:528:DC%2BD3sXmtFeqsLk%3D 12777371 (Pubitemid 36994581)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.33 , pp. 30748-30754
    • Weggen, S.1    Eriksen, J.L.2    Sagi, S.A.3    Pietrzik, C.U.4    Golde, T.E.5    Koo, E.H.6
  • 14
    • 27744462871 scopus 로고    scopus 로고
    • 2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease
    • DOI 10.1523/JNEUROSCI.3591-05.2005
    • X. Liang Q. Wang T. Hand L. Wu R.M. Breyer T.J. Montine, et al. 2005 Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease J Neurosci 25 10180 10187 10.1523/JNEUROSCI.3591-05.2005 1:CAS:528:DC%2BD2MXht1Wqt77I 16267225 (Pubitemid 41636214)
    • (2005) Journal of Neuroscience , vol.25 , Issue.44 , pp. 10180-10187
    • Liang, X.1    Wang, Q.2    Hand, T.3    Wu, L.4    Breyer, R.M.5    Montine, T.J.6    Andreasson, K.7
  • 15
    • 3042601107 scopus 로고    scopus 로고
    • 2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons
    • DOI 10.1016/j.neuint.2004.02.005, PII S019701860400035X
    • T. Takadera Y. Shiraishi T. Ohyashiki 2004 Prostaglandin E2 induced caspase-dependent apoptosis possibly through activation of EP2 receptors in cultured hippocampal neurons Neurochem Int 45 713 719 10.1016/j.neuint.2004.02. 005 1:CAS:528:DC%2BD2cXlsVart7g%3D 15234114 (Pubitemid 38844893)
    • (2004) Neurochemistry International , vol.45 , Issue.5 , pp. 713-719
    • Takadera, T.1    Shiraishi, Y.2    Ohyashiki, T.3
  • 16
    • 27844525476 scopus 로고    scopus 로고
    • 2 receptors EP2 and EP4 protects cultured neurons against oxidative stress and cell death following β-amyloid exposure
    • DOI 10.1111/j.1460-9568.2005.04427.x
    • V. Echeverria A. Clerman S. Dore 2005 Stimulation of PGE receptors EP2 and EP4 protects cultured neurons against oxidative stress and cell death following beta-amyloid exposure Eur J Neurosci 22 2199 2206 10.1111/j.1460-9568. 2005.04427.x 16262658 (Pubitemid 41653533)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.9 , pp. 2199-2206
    • Echeverria, V.1    Clerman, A.2    Dore, S.3
  • 17
    • 4243088105 scopus 로고    scopus 로고
    • Effect of hypercholesterolemia and of oxidative stress on the nitric oxide-cGMP pathway
    • DOI 10.1016/j.neuint.2004.04.007, PII S0197018604000749
    • H. Slawik B. Volk B. Fiebich M. Hull 2004 Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum Neurochem Int 45 653 660 10.1016/j.neuint.2004.04.007 1:CAS:528:DC%2BD2cXmtlChtrY%3D 15234107 (Pubitemid 38844886)
    • (2004) Neurochemistry International , vol.45 , Issue.5 , pp. 653-659
    • Francois, M.1    Kojda, G.2
  • 18
    • 17444410014 scopus 로고    scopus 로고
    • Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons
    • 1:CAS:528:DC%2BD2MXktlOht74%3D 15912885
    • F.S. Shie K.S. Montine R.M. Breyer T.J. Montine 2005 Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons Brain Pathol 15 134 138 1:CAS:528: DC%2BD2MXktlOht74%3D 15912885
    • (2005) Brain Pathol , vol.15 , pp. 134-138
    • Shie, F.S.1    Montine, K.S.2    Breyer, R.M.3    Montine, T.J.4
  • 20
    • 18244380066 scopus 로고    scopus 로고
    • 2 EP2 receptor in permanent focal cerebral ischemia
    • DOI 10.1002/ana.20461
    • D. Liu L. Wu R. Breyer M.P. Mattson K. Andreasson 2005 Neuroprotection by the PGE2 EP2 receptor in permanent focal cerebral ischemia Ann Neurol 57 758 761 10.1002/ana.20461 1:CAS:528:DC%2BD2MXkvFykt7c%3D 15852374 (Pubitemid 40628868)
    • (2005) Annals of Neurology , vol.57 , Issue.5 , pp. 758-761
    • Liu, D.1    Wu, L.2    Breyer, R.3    Mattson, M.P.4    Andreasson, K.5
  • 23
    • 22344439814 scopus 로고    scopus 로고
    • Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2
    • 1:CAS:528:DC%2BD2MXlvVSqu7s%3D 15855407
    • H. Fujino S. Salvi J.W. Regan 2005 Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2 Mol Pharmacol 68 251 259 1:CAS:528:DC%2BD2MXlvVSqu7s%3D 15855407
    • (2005) Mol Pharmacol , vol.68 , pp. 251-259
    • Fujino, H.1    Salvi, S.2    Regan, J.W.3
  • 24
    • 34249729416 scopus 로고    scopus 로고
    • Prostaglandin E receptors
    • DOI 10.1074/jbc.R600038200
    • Y. Sugimoto S. Narumiya 2007 Prostaglandin E receptors J Biol Chem 282 11613 11617 10.1074/jbc.R600038200 1:CAS:528:DC%2BD2sXktFemtbs%3D 17329241 (Pubitemid 47100657)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.16 , pp. 11613-11617
    • Sugimoto, Y.1    Narumiya, S.2
  • 25
    • 17144380506 scopus 로고    scopus 로고
    • Microglia lacking e Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity
    • 1:CAS:528:DC%2BD2MXjsFaksLc%3D 15793296
    • F.S. Shie R.M. Breyer T.J. Montine 2005 Microglia lacking E Prostanoid Receptor subtype 2 have enhanced Abeta phagocytosis yet lack Abeta-activated neurotoxicity Am J Pathol 166 1163 1172 1:CAS:528:DC%2BD2MXjsFaksLc%3D 15793296
    • (2005) Am J Pathol , vol.166 , pp. 1163-1172
    • Shie, F.S.1    Breyer, R.M.2    Montine, T.J.3
  • 26
    • 29544440041 scopus 로고    scopus 로고
    • Prostaglandin EP1 receptor contributes to excitotoxicity and focal ischemic brain damage
    • DOI 10.1093/toxsci/kfj022
    • A.S. Ahmad S. Saleem M. Ahmad S. Dore 2006 Prostaglandin EP1 receptor contributes to excitotoxicity and focal ischemic brain damage Toxicol Sci 89 265 270 10.1093/toxsci/kfj022 1:CAS:528:DC%2BD2MXhtlagtLfM 16237196 (Pubitemid 43013774)
    • (2006) Toxicological Sciences , vol.89 , Issue.1 , pp. 265-270
    • Ahmad, A.S.1    Saleem, S.2    Ahmad, M.3    Dore, S.4
  • 27
    • 33644504214 scopus 로고    scopus 로고
    • 2 deteriorates N-methyl-D-aspartate receptor-mediated cytotoxicity possibly by activating EP2 receptors in cultured cortical neurons
    • DOI 10.1016/j.lfs.2005.08.026, PII S0024320505010398
    • T. Takadera T. Ohyashiki 2006 Prostaglandin E2 deteriorates N-methyl-D-aspartate receptor-mediated cytotoxicity possibly by activating EP2 receptors in cultured cortical neurons Life Sci 78 1878 1883 10.1016/j.lfs.2005.08.026 1:CAS:528:DC%2BD28Xhsl2hsbs%3D 16309709 (Pubitemid 43295588)
    • (2006) Life Sciences , vol.78 , Issue.16 , pp. 1878-1883
    • Takadera, T.1    Ohyashiki, T.2
  • 28
    • 2942598274 scopus 로고    scopus 로고
    • 2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia
    • DOI 10.1016/j.neulet.2004.03.013, PII S0304394004002927
    • A.M. Pooler A.A. Arjona R.K. Lee R.J. Wurtman 2004 Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia Neurosci Lett 362 127 130 10.1016/j.neulet.2004.03.013 1:CAS:528:DC%2BD2cXktlCqsb8%3D 15193769 (Pubitemid 38759083)
    • (2004) Neuroscience Letters , vol.362 , Issue.2 , pp. 127-130
    • Pooler, A.M.1    Arjona, A.A.2    Lee, R.K.3    Wurtman, R.J.4
  • 29
    • 34250620551 scopus 로고    scopus 로고
    • Divergent effects of prostaglandin receptor signaling on neuronal survival
    • DOI 10.1016/j.neulet.2007.05.055, PII S0304394007006386
    • L. Wu Q. Wang X. Liang K. Andreasson 2007 Divergent effects of prostaglandin receptor signaling on neuronal survival Neurosci Lett 421 253 258 10.1016/j.neulet.2007.05.055 1:CAS:528:DC%2BD2sXmvVOgs7Y%3D 17574754 (Pubitemid 46935366)
    • (2007) Neuroscience Letters , vol.421 , Issue.3 , pp. 253-258
    • Wu, L.1    Wang, Q.2    Liang, X.3    Andreasson, K.4
  • 30
    • 4444271426 scopus 로고    scopus 로고
    • Mechanisms involved in prostaglandin E2-mediated neuroprotection against TNF-α: Possible involvement of multiple signal transduction and β-catenin/T-cell factor
    • DOI 10.1016/j.jneuroim.2004.05.012, PII S0165572804001882
    • E.O. Lee Y.J. Shin Y.H. Chong 2004 Mechanisms involved in prostaglandin E2-mediated neuroprotection against TNF-alpha: possible involvement of multiple signal transduction and betacatenin/T-cell factor J Neuroimmunol 155 21 31 10.1016/j.jneuroim.2004.05.012 1:CAS:528:DC%2BD2cXntlSnsro%3D 15342193 (Pubitemid 39165774)
    • (2004) Journal of Neuroimmunology , vol.155 , Issue.1-2 , pp. 21-31
    • Lee, E.O.1    Shin, Y.J.2    Chong, Y.H.3
  • 31
    • 0034670173 scopus 로고    scopus 로고
    • Pharmacology of the receptors for the phorbol ester tumor promoters: Multiple receptors with different biochemical properties
    • DOI 10.1016/S0006-2952(00)00470-6, PII S0006295200004706
    • M.G. Kazanietz M.J. Caloca P. Eroles T. Fujii M.L. Garcia-Bermejo M. Reilly, et al. 2000 Pharmacology of the receptors for the phorbol ester tumor promoters: multiple receptors with different biochemical properties Biochem Pharmacol 60 1417 1424 10.1016/S0006-2952(00)00470-6 1:CAS:528: DC%2BD3cXntVWgsrs%3D 11020443 (Pubitemid 30742605)
    • (2000) Biochemical Pharmacology , vol.60 , Issue.10 , pp. 1417-1424
    • Kazanietz, M.G.1    Caloca, M.J.2    Eroles, P.3    Fujii, T.4    Garcia-Bermejo, M.L.5    Reilly, M.6    Wang, H.7
  • 32
    • 23644454848 scopus 로고    scopus 로고
    • The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation
    • DOI 10.1016/j.brainres.2005.05.043, PII S0006899305007791
    • L. Hui D.S. Pei Q.G. Zhang Q.H. Guan G.Y. Zhang 2005 The neuroprotection of insulin on ischemic brain injury in rat hippocampus through negative regulation of JNK signaling pathway by PI3K/Akt activation Brain Res 1052 1 9 10.1016/j.brainres.2005.05.043 1:CAS:528:DC%2BD2MXnslyisbo%3D 16018989 (Pubitemid 41116281)
    • (2005) Brain Research , vol.1052 , Issue.1 , pp. 1-9
    • Hui, L.1    Pei, D.-S.2    Zhang, Q.-G.3    Guan, Q.-H.4    Zhang, G.-Y.5
  • 34
    • 0036221333 scopus 로고    scopus 로고
    • The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut
    • 1:CAS:528:DC%2BD38Xis1Kju70%3D 11927615
    • K. Kabashima T. Saji T. Murata M. Nagamachi T. Matsuoka E. Segi, et al. 2002 The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut J Clin Invest 109 883 893 1:CAS:528: DC%2BD38Xis1Kju70%3D 11927615
    • (2002) J Clin Invest , vol.109 , pp. 883-893
    • Kabashima, K.1    Saji, T.2    Murata, T.3    Nagamachi, M.4    Matsuoka, T.5    Segi, E.6
  • 36
    • 27444436866 scopus 로고    scopus 로고
    • Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity
    • DOI 10.1002/glia.20220
    • F.S. Shie K.S. Montine R.M. Breyer T.J. Montine 2005 Microglial EP2 is critical to neurotoxicity from activated cerebral innate immunity Glia 52 70 77 10.1002/glia.20220 15920732 (Pubitemid 41532139)
    • (2005) GLIA , vol.52 , Issue.1 , pp. 70-77
    • Shie, F.-S.1    Montine, K.S.2    Breyer, R.M.3    Montine, T.J.4
  • 37
    • 33846668868 scopus 로고    scopus 로고
    • 2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein
    • DOI 10.1186/1742-2094-4-2
    • J. Jin F.S. Shie J. Liu Y. Wang J. Davis A.M. Schantz, et al. 2007 Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alphasynuclein J Neuroinflammation 4 2 10.1186/1742-2094-4-2 17204153 (Pubitemid 46189718)
    • (2007) Journal of Neuroinflammation , vol.4 , pp. 2
    • Jin, J.1    Shie, F.-S.2    Liu, J.3    Wang, Y.4    Davis, J.5    Schantz, A.M.6    Montine, K.S.7    Montine, T.J.8    Zhang, J.9
  • 38
    • 0036082805 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity
    • 1:CAS:528:DC%2BD38XltFSksrs%3D 12037188
    • C. Chen J.C. Magee N.G. Bazan 2002 Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity J Neurophysiol 87 2851 2857 1:CAS:528:DC%2BD38XltFSksrs%3D 12037188
    • (2002) J Neurophysiol , vol.87 , pp. 2851-2857
    • Chen, C.1    Magee, J.C.2    Bazan, N.G.3
  • 41
    • 0041876229 scopus 로고    scopus 로고
    • Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid β42 production by direct modulation of γ-secretase activity
    • DOI 10.1074/jbc.M303592200
    • S. Weggen J.L. Eriksen S.A. Sagi C.U. Pietrzik V. Ozols A. Fauq, et al. 2003 Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gammasecretase activity J Biol Chem 278 31831 31837 10.1074/jbc.M303592200 1:CAS:528:DC%2BD3sXmsVOntbY%3D 12805356 (Pubitemid 37048365)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.34 , pp. 31831-31837
    • Weggen, S.1    Eriksen, J.L.2    Sagi, S.A.3    Pietrzik, C.U.4    Ozols, V.5    Fauq, A.6    Golde, T.E.7    Koo, E.H.8
  • 42
    • 43849096436 scopus 로고    scopus 로고
    • Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia
    • 10.1016/j.neulet.2008.04.054 1:CAS:528:DC%2BD1cXmtlWhsrs%3D 18472336
    • J. Li X. Liang Q. Wang R.M. Breyer L. McCullough K. Andreasson 2008 Misoprostol, an anti-ulcer agent and PGE2 receptor agonist, protects against cerebral ischemia Neurosci Lett 438 210 215 10.1016/j.neulet.2008.04.054 1:CAS:528:DC%2BD1cXmtlWhsrs%3D 18472336
    • (2008) Neurosci Lett , vol.438 , pp. 210-215
    • Li, J.1    Liang, X.2    Wang, Q.3    Breyer, R.M.4    McCullough, L.5    Andreasson, K.6
  • 44
    • 3843129633 scopus 로고    scopus 로고
    • 2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis
    • DOI 10.1002/ana.20179
    • M. Bilak L. Wu Q. Wang N. Haughey K. Conant C. St Hillaire, et al. 2004 PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis Ann Neurol 56 240 248 10.1002/ana.20179 1:CAS:528:DC%2BD2cXnt1enurg%3D 15293276 (Pubitemid 39037919)
    • (2004) Annals of Neurology , vol.56 , Issue.2 , pp. 240-248
    • Bilak, M.1    Wu, L.2    Wang, Q.3    Haughey, N.4    Conant, K.5    St. Hillaire, C.6    Andreasson, K.7
  • 45
    • 0035369623 scopus 로고    scopus 로고
    • Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
    • DOI 10.1016/S0959-4388(00)00211-7
    • A. Brunet S.R. Datta M.E. Greenberg 2001 Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway Curr Opin Neurobiol 11 297 305 10.1016/S0959-4388(00)00211-7 1:CAS:528: DC%2BD3MXks1Oktbw%3D 11399427 (Pubitemid 32524094)
    • (2001) Current Opinion in Neurobiology , vol.11 , Issue.3 , pp. 297-305
    • Brunet, A.1    Datta, S.R.2    Greenberg, M.E.3
  • 46
    • 18844418172 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced expression of cyclooxygenase-2 in PC-12 cells by triptolide
    • 1:CAS:528:DC%2BD28XhvF2jtbY%3D
    • W. Chen Y.D. Shen H.P. Yao G.S. Zhao 2005 Inhibition of lipopolysaccharide-induced expression of cyclooxygenase-2 in PC-12 cells by triptolide Chin Pharm J 40 274 277 1:CAS:528:DC%2BD28XhvF2jtbY%3D
    • (2005) Chin Pharm J , vol.40 , pp. 274-277
    • Chen, W.1    Shen, Y.D.2    Yao, H.P.3    Zhao, G.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.