Effect of hypercholesterolemia and of oxidative stress on the nitric oxide-cGMP pathway

Neurochemistry International

Volumn 45, Issue 6, 2004, Pages 955-961

  Francois, Michèle ^a   Kojda, Georg ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Atherosclerosis; Cardiovascular disease; Endothelial dysfunction; Nitric oxide; Oxidative stress

Indexed keywords

CHOLESTEROL; CYCLIC GMP; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; MEMBRANE PROTEIN; NITRIC OXIDE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ATHEROSCLEROSIS; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR DISEASE; CONFERENCE PAPER; ENDOTHELIUM LESION; ENZYME ACTIVITY; FEEDBACK SYSTEM; HYPERCHOLESTEROLEMIA; INFLAMMATION; INTIMA; NITRATION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RABBIT; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; UPREGULATION; VASCULAR RING; VASODILATATION;

ANIMALS; BLOOD PLATELETS; BLOOD VESSELS; CYCLIC GMP; GUANYLATE CYCLASE; HUMANS; HYPERCHOLESTEROLEMIA; NITRIC OXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION;

ORYCTOLAGUS CUNICULUS;

EID: 4243088105     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2004.03.026     Document Type: Conference Paper

References (62)

1. Azuma H., Ishikawa M., Sekizaki S. Endothelium-dependent inhibition of platelet aggregation. Br. J. Pharmacol. 88:1986;411-415
2. Bauersachs J., Bouloumié A., Mülsch A., Wiener G., Fleming I., Busse R. Vasodilator dysfunction in aged spontaneously hypertensive rats: changes in NO sythase III and soluble guanylyl cyclase expression, and in superoxide anion production. Cardiovasc. Res. 37(3):1998;772-779
3. Benjamin N., Dutton J.A.E., Ritter J.M. Human vascular smooth muscle cells inhibit platelet aggregation when incubated with glyceryl trinitrate: evidence for generation of nitric oxide. Br. J. Pharmacol. 102:1991;847-850
4. Bohlen H.G., Lash J.M. Active and passive arteriolar regulation in spontaneously hypertensive rats. Hypertension. 23:1994;757-764
5. Bonini M.G., Augusto O. Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite. J. Biol. Chem. 276:2001;9749-9754
6. Brandes R.P., Kim D.Y., Schmitz-Winnenthal F.H., Amidi M., Gödecke A., Mülsch A., Busse R. Increased nitrovasodilator sensitivity in endothelial nitric oxide synthase knockout mice: role of soluble guanylyl cyclase. Hypertension. 35:2000;231-236
7. Busse R., Fleming I. Endothelial dysfunction in atherosclerosis. J. Vasc. Res. 33:1996;181-194
8. 2+ influx. Circ. Res. 84:1999;210-219
9. Denicola A., Souza J.M., Radi R. Diffusion of peroxynitrite across erythrocyte membranes. Proc. Natl. Acad. Sci. U.S.A. 95:1998;3566-3571
10. Filippov G., Bloch D.B., Bloch K.D. Nitric oxide decreases stability of mRNAs encoding soluble guanylate cyclase subunits in rat pulmonary artery smooth muscle cells. J. Clin. Invest. 100:1997;942-948
11. Freedman J.E., Sauter R., Battinelli E.M., Ault K., Knowles C., Huang P.L., Loscalzo J. Deficient platelet-derived nitric oxide and enhanced hemostasis in mice lacking the NOSIII gene. Circ. Res. 84:1999;1416-1421
12. Friebe A., Koesling D. Regulation of nitric oxide-sensitive guanylyl cyclase. Circ. Res. 93:2003;96-105
13. Friebe A., Wedel B., Harteneck C., Foerster J., Schultz G., Koesling D. Functions of conserved cysteines of soluble guanylyl cyclase. Biochemistry. 36:1997;1194-1198
14. Geiger J., Nolte C., Walter U. Regulation of calcium mobilization and entry in human platelets by endothelium-derived factors. Am. J. Physiol. Cell Physiol. 267:1994;C236-C244
15. Gewaltig M.T., Kojda G. Vasoprotection by nitric oxide: mechanisms and therapeutic potential. Cardiovasc. Res. 55:2002;250-260
16. 2·: a pulse radiolysis study. Free Radic. Biol. Med. 19:1995;505-510
17. Horowitz A., Menice C.B., Laporte R., Morgan K.G. Mechanisms of smooth muscle contraction. Physiol. Rev. 76:1996;967-1003
18. Hussain M.B., Hobbs A.J., MacAllister R.J. Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta. Br. J. Pharmacol. 128:1999;1082-1088
19. Ignarro L.J., Cirino G., Casini A., Napoli C. Nitric oxide as a signaling molecule in the vascular system: an overview. J. Cardiovasc. Pharmacol. 34:1999;879-886
20. Ignarro L.J., Wood K.S., Wolin M.S. Activation of purified soluble guanylate cyclase by protoporphyrin IX. Proc. Natl. Acad. Sci. U.S.A. 79:1982;2870-2873
21. Ischiropoulos H., Zhu L., Chen J., Tsai M., Martin J.C., Smith C.D., Beckman J.S. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch. Biochem. Biophys. 298:1992;431-437
22. Khairutdinov R.F., Coddington J.W., Hurst J.K. Permeation of phospholipid membranes by peroxynitrite. Biochemistry. 39:2000;14238-14249
23. Kober T., Konig I., Weber M., Kojda G. Diethyldithiocarbamate inhibits the catalytic activity of xanthine oxidase. FEBS Lett. 551:2003;99-103
24. Koesling D. Modulators of soluble guanylyl cyclase. Naunyn Schmiedebergs Arch. Pharmacol. 358:1998;123-126
25. Kojda G., Harrison D.G. Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure. Cardiovasc. Res. 43:1999;562-571
26. Kojda G., Kottenberg K., Hacker A., Noack E. Alterations of the vascular and the myocardial guanylate cyclase/cGMP-system induced by long-term hypertension in rats. Pharm. Acta Helv. 73:1998a;27-35
27. Kojda G., Kottenberg K., Nix P., Schlüter K.D., Piper H.M., Noack E. Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes. Circ. Res. 78:1996;91-101
28. Kojda G., Laursen J.B., Ramasamy S., Kent J.D., Kurz S., Burchfield J., Shesely E.G., Harrison D.G. Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial nitric oxide synthase: contributions of NOS isoforms to blood pressure and heart rate control. Cardiovasc. Res. 42:1999;206-213
29. Kojda G., Patzner M., Hacker A., Noack E. Nitric oxide inhibits vascular bioactivation of glyceryl trinitrate. A novel mechanism to explain preferential venodilation of organic nitrates. Mol. Pharmacol. 53:1998b;547-554
30. Kottenberg-Assenmacher E., Weber M., Kojda G. The effect of hypercholesterolemia on platelet soluble guanylyl cyclase. Vasc. Pharmacol. 40:2003;141-147
31. Laber U., Kober T., Schmitz V., Schrammel A., Meyer W., Mayer B., Weber M., Kojda G. Effect of hypercholesterolemia on expression and function of vascular soluble guanylyl cyclase. Circulation. 105:2002;855-860
32. Loscalzo J. Nitric oxide insufficiency, platelet activation, and arterial thrombosis. Circ. Res. 88:2001;756-762
33. Lucas K.A., Pitari G.M., Kazerounian S., Ruiz-Stewart I., Park J., Schulz S., Chepenik K.P., Waldman S.A. Guanylyl cyclases and signaling by cyclic GMP. Pharmacol. Rev. 52:2000;375-414
34. Massberg S., Sausbier M., Klatt P., Bauer M., Pfeifer A., Siess W., Fässler R., Ruth P., Krombach F., Hofmann F. Increased adhesion and aggregation of platelets lacking cyclic guanosine 3′,5′- monophosphate kinase I. J. Exp. Med. 189:1999;1255-1263
35. Moncada S., Rees D.D., Schulz R., Palmer R.M.J. Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. Proc. Natl. Acad. Sci. U.S.A. 88:1991;2166-2170
36. Moritoki H., Tanioka A., Maeshiba Y., Iwamoto T., Ishida Y., Araki H. Age-associated decrease in histamine-induced vasodilation may be due to reduction of cyclic GMP formation. Br. J. Pharmacol. 95:1988;1015-1022
37. Moro M.A., Russell R.J., Cellek S., Lizasoain I., Su Y.C., Darley-Usmar V.M., Radomski M.W., Moncada S. cGMP mediates the vascular and platelet actions of nitric oxide: Confirmation using an inhibitor of the soluble guanylyl cyclase. Proc. Natl. Acad. Sci. U.S.A. 93:1996;1480-1485
38. Mourlon-Le Grand M.C., Benessiano J., Levy B.I. cGMP pathway and mechanical properties of carotid artery wall in WKY rats and SHR: role of endothelium. Am. J. Physiol. Heart Circ. Physiol. 263:1992;H61-H67
39. Mullershausen F., Russwurm M., Koesling D., Friebe A. The enhanced NO-induced cGMP response induced by long-term L-NAME treatment is not due to enhanced expression of NO-sensitive guanylyl cyclase. Vasc. Pharmacol. 40:2003;161-165
40. Mülsch, A., Weber, M., Klös, S., Behrens, M., Lauer, N., Kojda, G., 2000. Impairment of soluble guanylyl cyclase by peroxynitrite (Ref Type: Abstract). Circulation 102(18)II, 351.
41. Nguyen B.L., Saitoh M., Ware J.A. Interaction of nitric oxide and cGMP with signal transduction in activated platelets. Am. J. Physiol. Heart Circ. Physiol. 261:1991;H1043-H1052
42. Papapetropoulos A., Marczin N., Mora G., Milici A., Murad F., Catravas J.D. Regulation of vascular smooth muscle soluble guanylate cyclase activity, mRNA, and protein levels by cAMP-elevating agents. Hypertension. 26:1995;696-704
43. Pfeiffer S., Schmidt K., Mayer B. Dityrosine formation outcompetes tyrosine nitration at low steady-state concentrations of peroxynitrite: implications for tyrosine modification by nitric oxide/superoxide in vivo. J. Biol. Chem. 275:2000;6346-6352
44. Preik M., Kelm M., Feelisch M., Strauer B.E. Impaired effectiveness of nitric oxide-donors in resistance arteries of patients with arterial hypertension. J. Hypertension. 14:1996;903-908
45. Radi R., Beckman J.S., Bush K.M., Freeman B.A. Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266:1991;4244-4250
46. Radomski M.W., Moncada S. Regulation of vascular hemostasis by nitric oxide. Thromb. Haemost. 70:1993;36-41
47. Radomski M.W., Palmer R.M., Moncada S. The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide. Br. J. Pharmacol. 92:1987;639-646
48. Rao G.H., Krishnamurthi S., Raij L., White J.G. Influence of nitric oxide on agonist-mediated calcium mobilization in platelets. Biochem. Med. Metab. Biol. 43:1990;271-275
49. Robinson B.F., Dobbs R.J., Bayley S. Response of forearm resistance vessels to verapamil and sodium nitroprusside in normotensive and hypertensive men: evidence for a functional abnormality of vascular smooth muscle in primary hypertension. Clin. Sci. (Colch.). 63:1982;33-42
50. Romero N., Denicola A., Souza J.M., Radi R. Diffusion of peroxynitrite in the presence of carbon dioxide. Arch. Biochem. Biophys. 368:1999;23-30
51. Ronson R.S., Nakamura M., Vinten-Johansen J. The cardiovascular effects and implications of peroxynitrite. Cardiovasc. Res. 44:1999;47-59
52. Ross R. Mechanisms of disease: Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340:1999;115-126
53. Schlossmann J., Ammendola A., Ashman K., Zong X., Huber A., Neubauer G., Wang G.X., Allescher H.D., Korth M., Wilm M., Hofmann F., Ruth P. Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta. Nature. 404:2000;197-201
54. Schmidt K., Andrew P., Schrammel A., Groschner K., Schmitz V., Kojda G., Mayer B. Comparison of neuronal and endothelial isoforms of nitric oxide synthase in stably transfected HEK 293 cells. Am. J. Physiol. Heart Circ. Physiol. 281:2001;H2053-H2061
55. Schrammel A., Pfeiffer S., Schmidt K., Koesling D., Mayer B. Activation of soluble guanylyl cyclase by the nitrovasodilator 3-morpholinosydnonimine involves formation of S-nitrosoglutathione. Mol. Pharmacol. 54:1998;207-212
56. Shirasaki Y., Su C., Lee T.J., Kolm P., Cline W.H., Nickols G.A. Endothelial modulation of vascular relaxation to nitrovasodilators in aging and hypertension. J. Pharmacol. Exp. Ther. 239:1986;861-866
57. Teravainen T.L., Mervaala E.M., Porsti I., Laakso J., Vapaatalo H., Karppanen H. Influence of age and dietary sodium on the cardiovascular and renal effects of ramipril in spontaneously hypertensive rats. Methods Find. Exp. Clin. Pharmacol. 19:1997;311-321
58. Tremoli E., Colli S., Maderna P., Baldassarre D., Di Minno G. Hypercholesterolemia and platelets. Semin. Thromb. Hemost. 19:1993;115-121
59. 2+ stores. Circ. Res. 84:1999;201-209
60. Weber M., Lauer N., Mulsch A., Kojda G. The effect of peroxynitrite on the catalytic activity of soluble guanylyl cyclase. Free Radic. Biol. Med. 31:2001;1360-1367
61. Wolin M.S., Wood K.S., Ignarro L.J. Guanylate cyclase from bovine lung. A kinetic analysis of the regulation of the purified soluble enzyme by protoporphyrin IX, heme, and nitrosyl-heme. J. Biol. Chem. 257:1982;13312-13320
62. Yamashita T., Kawashima S., Ohashi Y., Ozaki M., Rikitake Y., Inoue N., Hirata K., Akita H., Yokoyama M. Mechanisms of reduced nitric oxide/cGMP-mediated vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase. Hypertension. 36:2000;97-102